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Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson’s Disease
- Mark P. Epping-Jordan,
- Françoise Girard,
- Anne-Sophie Bessis,
- Vincent Mutel,
- Christelle Boléa,
- Francis Derouet,
- Abdelhak Bessif,
- Brice Mingard,
- Stéphanie Barbier and
- Sonia Poli
- + 4 authors
Parkinson’s disease (PD) patients suffer not only from the primary motor symptoms of the disease but also from a range of non-motor symptoms (NMS) that cause disability and low quality of life. Excessive glutamate activity in the basal ganglia...