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1 Result Found

  • Article
  • Open Access
11 Citations
4,570 Views
18 Pages

Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models

  • Manuela Magni,
  • Beatrice Bossi,
  • Paola Conforti,
  • Maura Galimberti,
  • Fabio Dezi,
  • Tiziana Lischetti,
  • Xiaoling He,
  • Roger A. Barker,
  • Chiara Zuccato and
  • Ira Espuny-Camacho
  • + 1 author

29 October 2022

In vitro models of corticogenesis from pluripotent stem cells (PSCs) have greatly improved our understanding of human brain development and disease. Among these, 3D cortical organoid systems are able to recapitulate some aspects of in vivo cytoarchit...