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Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor
- David S. Lee,
- Rachel A. O’Keefe,
- Patrick K. Ha,
- Jennifer R. Grandis and
- Daniel E. Johnson
Cyclic STAT3 decoy (CS3D) is a second-generation, double-stranded oligodeoxynucleotide (ODN) that mimics a genomic response element for signal transducer and activator of transcription 3 (STAT3), an oncogenic transcription factor. CS3D competitively...