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30 pages, 1130 KiB  
Review
Beyond the Backbone: A Quantitative Review of Deep-Learning Architectures for Tropical Cyclone Track Forecasting
by He Huang, Difei Deng, Liang Hu, Yawen Chen and Nan Sun
Remote Sens. 2025, 17(15), 2675; https://doi.org/10.3390/rs17152675 (registering DOI) - 2 Aug 2025
Abstract
Accurate forecasting of tropical cyclone (TC) tracks is critical for disaster preparedness and risk mitigation. While traditional numerical weather prediction (NWP) systems have long served as the backbone of operational forecasting, they face limitations in computational cost and sensitivity to initial conditions. In [...] Read more.
Accurate forecasting of tropical cyclone (TC) tracks is critical for disaster preparedness and risk mitigation. While traditional numerical weather prediction (NWP) systems have long served as the backbone of operational forecasting, they face limitations in computational cost and sensitivity to initial conditions. In recent years, deep learning (DL) has emerged as a promising alternative, offering data-driven modeling capabilities for capturing nonlinear spatiotemporal patterns. This paper presents a comprehensive review of DL-based approaches for TC track forecasting. We categorize all DL-based TC tracking models according to the architecture, including recurrent neural networks (RNNs), convolutional neural networks (CNNs), Transformers, graph neural networks (GNNs), generative models, and Fourier-based operators. To enable rigorous performance comparison, we introduce a Unified Geodesic Distance Error (UGDE) metric that standardizes evaluation across diverse studies and lead times. Based on this metric, we conduct a critical comparison of state-of-the-art models and identify key insights into their relative strengths, limitations, and suitable application scenarios. Building on this framework, we conduct a critical cross-model analysis that reveals key trends, performance disparities, and architectural tradeoffs. Our analysis also highlights several persistent challenges, such as long-term forecast degradation, limited physical integration, and generalization to extreme events, pointing toward future directions for developing more robust and operationally viable DL models for TC track forecasting. To support reproducibility and facilitate standardized evaluation, we release an open-source UGDE conversion tool on GitHub. Full article
(This article belongs to the Section AI Remote Sensing)
15 pages, 560 KiB  
Article
Exploring the Material Feasibility of a LiFePO4-Based Energy Storage System
by Caleb Scarlett and Vivek Utgikar
Energies 2025, 18(15), 4102; https://doi.org/10.3390/en18154102 (registering DOI) - 1 Aug 2025
Abstract
This paper analyzes the availability of lithium resources required to support a global decarbonized energy system featuring electrical energy storage based on lithium iron phosphate (LFP) batteries. A net-zero carbon grid consisting of existing nuclear and hydro capacity, with the balance being a [...] Read more.
This paper analyzes the availability of lithium resources required to support a global decarbonized energy system featuring electrical energy storage based on lithium iron phosphate (LFP) batteries. A net-zero carbon grid consisting of existing nuclear and hydro capacity, with the balance being a 50/50 mix of wind and solar power generation, is assumed to satisfy projected world electrical demand in 2050, incorporating the electrification of transportation. The battery electrical storage capacity needed to support this grid is estimated and translated into the required number of nominal 10 MWh LFP storage plants similar to the ones currently in operation. The total lithium required for the global storage system is determined from the number of nominal plants and the inventory of lithium in each plant. The energy required to refine this amount of lithium is accounted for in the estimation of the total lithium requirement. Comparison of the estimated lithium requirements with known global lithium resources indicates that a global storage system consisting only of LFP plants would require only around 12.3% of currently known lithium reserves in a high-economic-growth scenario. The overall cost for a global LFP-based grid-scale energy storage system is estimated to be approximately USD 17 trillion. Full article
(This article belongs to the Collection Renewable Energy and Energy Storage Systems)
29 pages, 3508 KiB  
Article
Assessment of the Energy Efficiency of Individual Means of Transport in the Process of Optimizing Transport Environments in Urban Areas in Line with the Smart City Idea
by Grzegorz Augustyn, Jerzy Mikulik, Wojciech Lewicki and Mariusz Niekurzak
Energies 2025, 18(15), 4079; https://doi.org/10.3390/en18154079 (registering DOI) - 1 Aug 2025
Viewed by 136
Abstract
One of the fundamental goals of contemporary mobility is to optimize transport processes in urban areas. The solution in this area seems to be the implementation of the idea of sustainable transport systems based on the Smart City concept. The article presents a [...] Read more.
One of the fundamental goals of contemporary mobility is to optimize transport processes in urban areas. The solution in this area seems to be the implementation of the idea of sustainable transport systems based on the Smart City concept. The article presents a case study—an assessment of the possibilities of changing mobility habits based on the idea of sustainable urban transport, taking into account the criterion of energy consumption of individual means of transport. The analyses are based on a comparison of selected means of transport occurring in the urban environment according to several key parameters for the optimization and efficiency of transport processes, i.e., cost, time, travel comfort, and impact on the natural environment, while simultaneously linking them to the criterion of energy consumption of individual means of transport. The analyzed parameters currently constitute the most important group of challenges in the area of shaping and planning optimal and sustainable urban transport. The presented research was used to indicate the connections between various areas of optimization of the transport process and the energy efficiency of individual modes of transport. Analyses have shown that the least time-consuming process of urban mobility is associated with the highest level of CO2 emissions and, at the same time, the highest level of energy efficiency. However, combining public transport with other means of transport can meet most of the transport expectations of city residents, also in terms of energy optimization. The research results presented in the article can contribute to the creation of a strategy for the development of the transport network based on the postulates of increasing the optimization and efficiency of individual means of transport in urban areas. At the same time, recognizing the criterion of energy intensity of means of transport as leading in the development of sustainable urban mobility. Thus, confirming the important role of existing transport systems in the process of shaping and planning sustainable urban mobility in accordance with the idea of Smart City. Full article
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12 pages, 257 KiB  
Article
Evaluating the Diagnostic Potential of the FIB-4 Index for Cystic Fibrosis-Associated Liver Disease in Adults: A Comparison with Transient Elastography
by Stephen Armstrong, Kingston Rajiah, Aaron Courtenay, Nermeen Ali and Ahmed Abuelhana
J. Clin. Med. 2025, 14(15), 5404; https://doi.org/10.3390/jcm14155404 (registering DOI) - 31 Jul 2025
Viewed by 147
Abstract
Background/Objectives: Cystic fibrosis-associated liver disease (CFLD) is a significant complication in individuals with cystic fibrosis (CF), contributing to morbidity and mortality, with no universally accepted, reliable, non-invasive diagnostic tool for early detection. Current diagnostic methods, including liver biopsy and imaging, remain resource-intensive [...] Read more.
Background/Objectives: Cystic fibrosis-associated liver disease (CFLD) is a significant complication in individuals with cystic fibrosis (CF), contributing to morbidity and mortality, with no universally accepted, reliable, non-invasive diagnostic tool for early detection. Current diagnostic methods, including liver biopsy and imaging, remain resource-intensive and invasive. Non-invasive biomarkers like the Fibrosis-4 (FIB-4) index have shown promise in diagnosing liver fibrosis in various chronic liver diseases. This study explores the potential of the FIB-4 index to predict CFLD in an adult CF population and assesses its correlation with transient elastography (TE) as a potential diagnostic tool. The aim of this study is to evaluate the diagnostic performance of the FIB-4 index for CFLD in adults with CF and investigate its relationship with TE-based liver stiffness measurements (LSM). Methods: The study was conducted in a regional cystic fibrosis unit, including 261 adult CF patients. FIB-4 scores were calculated using an online tool (mdcalc.com) based on patient age, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and platelet count. In parallel, 29 patients underwent liver stiffness measurement using TE (Fibroscan®). Statistical analyses included non-parametric tests for group comparisons and Pearson’s correlation to assess the relationship between FIB-4 scores and TE results. Results: The mean FIB-4 score in patients diagnosed with CFLD was higher (0.99 ± 0.83) compared to those without CFLD (0.64 ± 0.38), although the difference was not statistically significant (p > 0.05). TE results for CFLD patients (5.9 kPa) also did not show a significant difference compared to non-CFLD patients (4.2 ± 1.6 kPa, p > 0.05). However, a positive correlation (r = 0.401, p = 0.031) was found between FIB-4 scores and TE-based LSM, suggesting a potential complementary diagnostic role. Conclusions: The FIB-4 index, while not sufficient as a standalone diagnostic tool for CFLD in adults with CF, demonstrates potential when used in conjunction with other diagnostic methods like TE. This study introduces a novel approach for integrating non-invasive diagnostic markers in CF care, offering a pathway for future clinical practice. The combination of FIB-4 and TE could serve as an accessible, cost-effective alternative to invasive diagnostic techniques, improving early diagnosis and management of CFLD in the CF population. Additionally, future research should explore the integration of these tools with emerging biomarkers and clinical features to refine diagnostic algorithms for CFLD, potentially reducing reliance on liver biopsies and improving patient outcomes. Full article
(This article belongs to the Section Intensive Care)
18 pages, 2664 KiB  
Article
Analysis of Heat Exchange Efficiency and Influencing Factors of Energy Tunnels: A Case Study of the Torino Metro in Italy
by Mei Yin, Pengcheng Liu and Zhenhuang Wu
Buildings 2025, 15(15), 2704; https://doi.org/10.3390/buildings15152704 (registering DOI) - 31 Jul 2025
Viewed by 138
Abstract
Both ground source heat pumps (GSHPs) and energy underground structures are engineered systems that utilize shallow geothermal energy. However, due to the construction complexity and associated costs of energy tunnels, their heat exchange efficiency relative to GSHPs remains a topic worthy of in-depth [...] Read more.
Both ground source heat pumps (GSHPs) and energy underground structures are engineered systems that utilize shallow geothermal energy. However, due to the construction complexity and associated costs of energy tunnels, their heat exchange efficiency relative to GSHPs remains a topic worthy of in-depth investigation. In this study, a thermal–hydraulic (TH) coupled finite element model was developed based on a section of the Torino Metro Line in Italy to analyze the differences in and influencing factors of heat transfer performance between energy tunnels and GSHPs. The model was validated by comparing the outlet temperature curves under both winter and summer loading conditions. Based on this validated model, a parametric analysis was conducted to examine the effects of the tunnel air velocity, heat carrier fluid velocity, and fluid type. The results indicate that, under identical environmental conditions, energy tunnels exhibit higher heat exchange efficiency than conventional GSHP systems and are less sensitive to external factors such as fluid velocity. Furthermore, a comparison of different heat carrier fluids, including alcohol-based fluids, refrigerants, and water, revealed that the fluid type significantly affects thermal performance, with the refrigerant R-134a outperforming ethylene glycol and water in both heating and cooling efficiency. Full article
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18 pages, 4971 KiB  
Article
Sustainable Production of Bacterial Cellulose in a Rotary Disk Bioreactor: Grape Pomace as a Replacement for the Carbon Source
by Rodrigo Cáceres, Patricio Oyarzún, Juan Pablo Vargas, Francisca Cuevas, Kelly Torres, Elizabeth Elgueta, Irene Martínez and Dariela Núñez
Fermentation 2025, 11(8), 441; https://doi.org/10.3390/fermentation11080441 (registering DOI) - 31 Jul 2025
Viewed by 154
Abstract
Bacterial nanocellulose (BNC) is a highly pure biopolymer with promising applications in the biomedical, food, and textile industries. However, the high production costs and low yields obtained in static conditions limit its scalability and industrial applications. This study addresses the sustainable production of [...] Read more.
Bacterial nanocellulose (BNC) is a highly pure biopolymer with promising applications in the biomedical, food, and textile industries. However, the high production costs and low yields obtained in static conditions limit its scalability and industrial applications. This study addresses the sustainable production of BNC using a rotary disk bioreactor (RDB) and explores the use of grape pomace extract as an alternative carbon source for BNC production. Parameters such as the BNC production and biomass yield were evaluated using Komagataeibacter xylinus ATCC 53524 under different operational conditions (disk surface, rotation speed, and number of disks). The results showed that cellulose production increased using silicone-coated disks at 7–9 rpm (up to 2.72 g L−1), while higher yields (5.23 g L−1) were achieved when using grape pomace extract as the culture medium in comparison with conventional HS medium. FTIR and TGA characterizations confirmed that BNC obtained with grape pomace extract presents the same thermal and chemical characteristics than BNC produced with HS medium. This work provides insight into the feasibility of upscaling BNC production using a bioprocessing strategy, combining production in the RDB system and the use of an agro-industrial waste as a sustainable and cost-effective alternative. Full article
(This article belongs to the Section Fermentation Process Design)
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16 pages, 1932 KiB  
Article
Parsing Old English with Universal Dependencies—The Impacts of Model Architectures and Dataset Sizes
by Javier Martín Arista, Ana Elvira Ojanguren López and Sara Domínguez Barragán
Big Data Cogn. Comput. 2025, 9(8), 199; https://doi.org/10.3390/bdcc9080199 - 30 Jul 2025
Viewed by 233
Abstract
This study presents the first systematic empirical comparison of neural architectures for Universal Dependencies (UD) parsing in Old English, thus addressing central questions in computational historical linguistics and low-resource language processing. We evaluate three approaches—a baseline spaCy pipeline, a pipeline with a pretrained [...] Read more.
This study presents the first systematic empirical comparison of neural architectures for Universal Dependencies (UD) parsing in Old English, thus addressing central questions in computational historical linguistics and low-resource language processing. We evaluate three approaches—a baseline spaCy pipeline, a pipeline with a pretrained tok2vec component, and a MobileBERT transformer-based model—across datasets ranging from 1000 to 20,000 words. Our results demonstrate that the pretrained tok2vec model consistently outperforms alternatives, because it achieves 83.24% UAS and 74.23% LAS with the largest dataset, whereas the transformer-based approach substantially underperforms despite higher computational costs. Performance analysis reveals that basic tagging tasks reach 85–90% accuracy, while dependency parsing achieves approximately 75% accuracy. We identify critical scaling thresholds, with substantial improvements occurring between 1000 and 5000 words and diminishing returns beyond 10,000 words, which provides insights into scaling laws for historical languages. Technical analysis reveals that the poor performance of the transformer stems from parameter-to-data ratio mismatches (1250:1) and the unique orthographic and morphological characteristics of Old English. These findings defy assumptions about transformer superiority in low-resource scenarios and establish evidence-based guidelines for researchers working with historical languages. The broader significance of this study extends to enabling an automated analysis of three million words of extant Old English texts and providing a framework for optimal architecture selection in data-constrained environments. Our results suggest that medium-complexity architectures with monolingual pretraining offer superior cost–benefit trade-offs compared to complex transformer models for historical language processing. Full article
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40 pages, 3463 KiB  
Review
Machine Learning-Powered Smart Healthcare Systems in the Era of Big Data: Applications, Diagnostic Insights, Challenges, and Ethical Implications
by Sita Rani, Raman Kumar, B. S. Panda, Rajender Kumar, Nafaa Farhan Muften, Mayada Ahmed Abass and Jasmina Lozanović
Diagnostics 2025, 15(15), 1914; https://doi.org/10.3390/diagnostics15151914 - 30 Jul 2025
Viewed by 345
Abstract
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, [...] Read more.
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, cross-domain ML applications, and a critical discussion on ethical integration in smart diagnostics. The review focuses on the role of big data analysis and ML towards better diagnosis, improved efficiency of operations, and individualized care for patients. It explores the principal challenges of data heterogeneity, privacy, computational complexity, and advanced methods such as federated learning (FL) and edge computing. Applications in real-world settings, such as disease prediction, medical imaging, drug discovery, and remote monitoring, illustrate how ML methods, such as deep learning (DL) and natural language processing (NLP), enhance clinical decision-making. A comparison of ML models highlights their value in dealing with large and heterogeneous healthcare datasets. In addition, the use of nascent technologies such as wearables and Internet of Medical Things (IoMT) is examined for their role in supporting real-time data-driven delivery of healthcare. The paper emphasizes the pragmatic application of intelligent systems by highlighting case studies that reflect up to 95% diagnostic accuracy and cost savings. The review ends with future directions that seek to develop scalable, ethical, and interpretable AI-powered healthcare systems. It bridges the gap between ML algorithms and smart diagnostics, offering critical perspectives for clinicians, data scientists, and policymakers. Full article
(This article belongs to the Special Issue Machine-Learning-Based Disease Diagnosis and Prediction)
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16 pages, 324 KiB  
Review
Social Nudging for Sustainable Electricity Use: Behavioral Interventions in Energy Conservation Policy
by Pratik Mochi, Kartik Pandya, Karen Byskov Lindberg and Magnus Korpås
Sustainability 2025, 17(15), 6932; https://doi.org/10.3390/su17156932 - 30 Jul 2025
Viewed by 304
Abstract
Traditional energy conservation policies have primarily relied on economic incentives and informational campaigns. However, recent insights from behavioral and social sciences indicate that subtle behavioral interventions, particularly social nudges, can significantly influence household electricity use. This paper presents a structured review of 23 [...] Read more.
Traditional energy conservation policies have primarily relied on economic incentives and informational campaigns. However, recent insights from behavioral and social sciences indicate that subtle behavioral interventions, particularly social nudges, can significantly influence household electricity use. This paper presents a structured review of 23 recent field studies examining how social nudging strategies, such as peer comparison, group identity, and normative messaging, have contributed to measurable reductions in electricity consumption. By analyzing intervention outcomes across different regions and formats, we identify key success factors, limitations, and policy implications. Special attention is given to ethical considerations, fairness in implementation, and potential challenges in sustaining behavior change. This study offers a framework for integrating social nudges into future energy policies, emphasizing their role as low-cost, scalable tools for promoting sustainable energy behavior. Full article
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22 pages, 6682 KiB  
Article
An FR4-Based Oscillator Loading an Additional High-Q Cavity for Phase Noise Reduction Using SISL Technology
by Jingwen Han, Ningning Yan and Kaixue Ma
Electronics 2025, 14(15), 3041; https://doi.org/10.3390/electronics14153041 - 30 Jul 2025
Viewed by 140
Abstract
An FR4-based X-band low phase noise oscillator loading an additional high-Q cavity resonator was designed in this study using substrate-integrated suspended line (SISL) technology. The additional resonator was coupled to an oscillator by the transmission line (coupling TL). The impact of the [...] Read more.
An FR4-based X-band low phase noise oscillator loading an additional high-Q cavity resonator was designed in this study using substrate-integrated suspended line (SISL) technology. The additional resonator was coupled to an oscillator by the transmission line (coupling TL). The impact of the additional resonator on startup conditions, Q factor enhancement, and phase noise reduction was thoroughly investigated. Three oscillators loading an additional high-Q cavity resonator, loading an additional high-Q cavity resonator and performing partial dielectric extraction, and loading an original parallel feedback oscillator for comparison were presented. The experimental results showed that the proposed oscillator had a low phase noise of −131.79 dBc/Hz at 1 MHz offset from the carrier frequency of 10.088 GHz, and the FOM was −197.79 dBc/Hz. The phase noise was reduced by 1.66 dB through loading the additional resonator and further reduced by 1.87 dB through partially excising the substrate. To the best of our knowledge, the proposed oscillator showed the lowest phase noise and FOM compared with other all-FR4-based oscillators. The cost of fabrication was markedly reduced. The proposed oscillator also has the advantages of compact size and self-packaging properties. Full article
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28 pages, 8824 KiB  
Article
Platform Approaches in the AEC Industry: Stakeholder Perspectives and Case Study
by Layla Mujahed, Gang Feng and Jianghua Wang
Buildings 2025, 15(15), 2684; https://doi.org/10.3390/buildings15152684 - 30 Jul 2025
Viewed by 197
Abstract
The architecture, engineering, and construction (AEC) industry faces challenges related to inefficiencies and fragmentation that highlight the need for advanced construction technologies and drive interest in innovative solutions such as the platform approach to design. This study assessed platform-based building design through (1) [...] Read more.
The architecture, engineering, and construction (AEC) industry faces challenges related to inefficiencies and fragmentation that highlight the need for advanced construction technologies and drive interest in innovative solutions such as the platform approach to design. This study assessed platform-based building design through (1) interviews with practitioners from China, Jordan, and the UK, which helped to define the platform approach in the AEC industry and the challenges involved, and (2) a residential building design simulation conducted to evaluate the potential of the platform approach. The simulated design’s materials costs, energy efficiency, and construction time were compared with those of the traditional building design. The results of the comparison corroborate the interview findings concerning practitioners’ perspectives on platform definition, benefits, challenges, and implementation. The findings also demonstrate the potential of the platform approach to enhance productivity and scalability through modularization, kit-of-parts configuration, and standardization. This research bridges the gap between theory and practice by supporting shareholder perspectives on building design and construction with the results of a simulated platform approach to a real-world design project. This research addresses the urgent need to better understand and test the platform approach to achieve material, energy, and construction time savings through collaborative and practice-informed design. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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24 pages, 11697 KiB  
Article
Layered Production Allocation Method for Dual-Gas Co-Production Wells
by Guangai Wu, Zhun Li, Yanfeng Cao, Jifei Yu, Guoqing Han and Zhisheng Xing
Energies 2025, 18(15), 4039; https://doi.org/10.3390/en18154039 - 29 Jul 2025
Viewed by 162
Abstract
The synergistic development of low-permeability reservoirs such as deep coalbed methane (CBM) and tight gas has emerged as a key technology to reduce development costs, enhance single-well productivity, and improve gas recovery. However, due to fundamental differences between coal seams and tight sandstones [...] Read more.
The synergistic development of low-permeability reservoirs such as deep coalbed methane (CBM) and tight gas has emerged as a key technology to reduce development costs, enhance single-well productivity, and improve gas recovery. However, due to fundamental differences between coal seams and tight sandstones in their pore structure, permeability, water saturation, and pressure sensitivity, significant variations exist in their flow capacities and fluid production behaviors. To address the challenges of production allocation and main reservoir identification in the co-development of CBM and tight gas within deep gas-bearing basins, this study employs the transient multiphase flow simulation software OLGA to construct a representative dual-gas co-production well model. The regulatory mechanisms of the gas–liquid distribution, deliquification efficiency, and interlayer interference under two typical vertical stacking relationships—“coal over sand” and “sand over coal”—are systematically analyzed with respect to different tubing setting depths. A high-precision dynamic production allocation method is proposed, which couples the wellbore structure with real-time monitoring parameters. The results demonstrate that positioning the tubing near the bottom of both reservoirs significantly enhances the deliquification efficiency and bottomhole pressure differential, reduces the liquid holdup in the wellbore, and improves the synergistic productivity of the dual-reservoirs, achieving optimal drainage and production performance. Building upon this, a physically constrained model integrating real-time monitoring data—such as the gas and liquid production from tubing and casing, wellhead pressures, and other parameters—is established. Specifically, the model is built upon fundamental physical constraints, including mass conservation and the pressure equilibrium, to logically model the flow paths and phase distribution behaviors of the gas–liquid two-phase flow. This enables the accurate derivation of the respective contributions of each reservoir interval and dynamic production allocation without the need for downhole logging. Validation results show that the proposed method reliably reconstructs reservoir contribution rates under various operational conditions and wellbore configurations. Through a comparison of calculated and simulated results, the maximum relative error occurs during abrupt changes in the production capacity, approximately 6.37%, while for most time periods, the error remains within 1%, with an average error of 0.49% throughout the process. These results substantially improve the timeliness and accuracy of the reservoir identification. This study offers a novel approach for the co-optimization of complex multi-reservoir gas fields, enriching the theoretical framework of dual-gas co-production and providing technically adaptive solutions and engineering guidance for multilayer unconventional gas exploitation. Full article
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19 pages, 775 KiB  
Article
Optimization of Mining Sequence for Ion-Adsorbed Rare Earth Mining Districts Incorporating Environmental Costs
by Lu Yi, Yi Zeng and Minggui Zheng
Sustainability 2025, 17(15), 6871; https://doi.org/10.3390/su17156871 - 29 Jul 2025
Viewed by 133
Abstract
The mining sequence of ionic rare earth mineral mining districts is related to the effective utilization of rare earth mineral resources and the protection of ecological environment. This study establishes an optimization model for the mining sequence of ion-adsorption rare earth mining districts [...] Read more.
The mining sequence of ionic rare earth mineral mining districts is related to the effective utilization of rare earth mineral resources and the protection of ecological environment. This study establishes an optimization model for the mining sequence of ion-adsorption rare earth mining districts that incorporates environmental costs, using the net present value (NPV) of the mining district and the net present value of environmental costs (CE) as objective functions. The model is applied to optimize the mining sequence of Mining District L. The results demonstrate that (1) Four algorithms, namely NSGA-II, NSGA-III, IBEA, and MOEA/D, were selected for comparison. The analysis based on the distribution of solutions, hypervolume values (HV), and computational time revealed that the IBEA exhibited superior performance. (2) The IBEA was employed to solve the multi-objective optimization problem, yielding a set of 30 optimal solutions. Different NPVs corresponded to different CE values, with the CE value increasing correspondingly as the NPV increased. (3) The weighted method was employed to transform the multi-objective optimization problem into a single-objective formulation. Using a genetic algorithm (GA), the optimal solution yielded a decision variable sequence for mining order as [2, 5, 8, 4, 1, 9, 6, 7, 3, 10, 11], with the net present value (NPV) of mining district profits reaching CNY 76,640.65 million and the environmental cost NPV amounting to CNY 19,469.18 million. Compared with the mining sequence optimization scheme that did not consider CE, although the NPV decreased by CNY 3.3266 million, the CE was reduced by CNY 10.6993 million. The mining sequence optimization model with environmental costs constructed in this paper provides a scientific decision-making basis for mining enterprises to consider the mining sequence in mining districts, minimize the damage to the ecological environment, and promote the coordinated progress of resource development and sustainable development. Full article
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11 pages, 556 KiB  
Article
Added Value of SPECT/CT in Radio-Guided Occult Localization (ROLL) of Non-Palpable Pulmonary Nodules Treated with Uniportal Video-Assisted Thoracoscopy
by Demetrio Aricò, Lucia Motta, Giulia Giacoppo, Michelangelo Bambaci, Paolo Macrì, Stefania Maria, Francesco Barbagallo, Nicola Ricottone, Lorenza Marino, Gianmarco Motta, Giorgia Leone, Carlo Carnaghi, Vittorio Gebbia, Domenica Caponnetto and Laura Evangelista
J. Clin. Med. 2025, 14(15), 5337; https://doi.org/10.3390/jcm14155337 - 29 Jul 2025
Viewed by 219
Abstract
Background/Objectives: The extensive use of computed tomography (CT) has led to a significant increase in the detection of small and non-palpable pulmonary nodules, necessitating the use of invasive methods for definitive diagnosis. Video-assisted thoracoscopic surgery (VATS) has become the preferred procedure for nodule [...] Read more.
Background/Objectives: The extensive use of computed tomography (CT) has led to a significant increase in the detection of small and non-palpable pulmonary nodules, necessitating the use of invasive methods for definitive diagnosis. Video-assisted thoracoscopic surgery (VATS) has become the preferred procedure for nodule resections; however, intraoperative localization remains challenging, especially for deep or subsolid lesions. This study explores whether SPECT/CT improves the technical and clinical outcomes of radio-guided occult lesion localization (ROLL) before uniportal video-assisted thoracoscopic surgery (u-VATS). Methods: This is a retrospective study involving consecutive patients referred for the resection of pulmonary nodules who underwent CT-guided ROLL followed by u-VATS between September 2017 and December 2024. From January 2023, SPECT/CT was systematically added after planar imaging. The cohort was divided into a planar group and a planar + SPECT/CT group. The inclusion criteria involved nodules sized ≤ 2 cm, with ground glass or solid characteristics, located at a depth of <6 cm from the pleural surface. 99mTc-MAA injected activity, timing, the classification of planar and SPECT/CT image findings (focal uptake, multisite with focal uptake, multisite without focal uptake), spillage, and post-procedure complications were evaluated. Statistical analysis was performed, with continuous data expressed as the median and categorical data as the number. Comparisons were made using chi-square tests for categorical variables and the Mann–Whitney U test for procedural duration. Cohen’s kappa coefficient was calculated to assess agreement between imaging modalities. Results: In total, 125 patients were selected for CT-guided radiotracer injection followed by uniportal-VATS. The planar group and planar + SPECT/CT group comprised 60 and 65 patients, respectively. Focal uptake was detected in 68 (54%), multisite with focal uptake in 46 (36.8%), and multisite without focal uptake in 11 patients (8.8%). In comparative analyses between planar and SPECT/CT imaging in 65 patients, 91% exhibited focal uptake, revealing significant differences in classification for 40% of the patients. SPECT/CT corrected the classification of 23 patients initially categorized as multisite with focal uptake to focal uptake, improving localization accuracy. The mean procedure duration was 39 min with SPECT/CT. Pneumothorax was more frequently detected with SPECT/CT (43% vs. 1.6%). The intraoperative localization success rate was 96%. Conclusions: SPECT/CT imaging in the ROLL procedure for detecting pulmonary nodules before u-VATs demonstrates a significant advantage in reclassifying radiotracer positioning compared to planar imaging. Considering its limited impact on surgical success rates and additional procedural time, SPECT/CT should be reserved for technically challenging cases. Larger sample sizes, multicentric and prospective randomized studies, and formal cost–utility analyses are warranted. Full article
(This article belongs to the Section Nuclear Medicine & Radiology)
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16 pages, 1443 KiB  
Article
Organomineral Fertilizer in Planting of Potato Cultivars Ágata and Atlantic
by Mara Lúcia Martins Magela, José Magno Queiroz Luz, Regina Maria Quintão Lana, Rayssa Camargo de Oliveira, Luciana Nunes Gontijo, Rafael Resende Finzi, Gabriel Mascarenhas Maciel and Ana Carolina Silva Siquieroli
Agronomy 2025, 15(8), 1833; https://doi.org/10.3390/agronomy15081833 - 29 Jul 2025
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Abstract
Given the importance of potatoes in Brazilian agribusiness and the need to establish sustainable production systems, interest has increased in the implementation of more efficient fertilization methods for the cultivation. Thus, the objective of this study was to evaluate the response of the [...] Read more.
Given the importance of potatoes in Brazilian agribusiness and the need to establish sustainable production systems, interest has increased in the implementation of more efficient fertilization methods for the cultivation. Thus, the objective of this study was to evaluate the response of the cultivars Ágata and Atlantic to fertilization with a pelleted organomineral source in comparison to conventional fertilization performed with a mineral source. A causal block design was used with five treatments [100% of the recommendation for fertilization with mineral sources 03-35-06; and 100%, 80%, 60%, and 40% of the recommended dose with organomineral fertilizer (02-20-05)] in four replications, totaling 20 plots. The application of the organomineral in plant fertilization can be an interesting source of fertilizer for the cultivation of Ágata and Atlantic potatoes and can be applied with dose adjustments. For the cultivar Ágata, the doses of 100% and 80% organomineral fertilizer together with mineral fertilization resulted in the highest total yields. The lower doses (60% and 40%) made it possible to obtain a higher percentage of special potatoes, considered to be of the highest commercial value, than 80% of the organomineral fertilizers and 100% mineral standard. For the Atlantic cultivar, the total yield responses to organomineral were like those obtained with exclusively mineral fertilization. These findings indicate that organomineral fertilizers can be used efficiently with adjusted doses, maintaining productivity and tuber quality while potentially reducing fertilizer input costs and environmental impacts, contributing to more sustainable potato cropping systems. Full article
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