Search Results (2,521)

We report on the welding of optical borosilicate glass to an unpolished copper substrate (surface Ra of 0.27 µm and Rz of 1.89 µm) using bursts of femtosecond laser pulses. The present paper puts forth the hypothesis that glass–metal welding with a gap is contingent upon the ejection of molten jets of glass. We have ascertained the impact of pulse energy and focal position on weldability. This finding serves to substantiate our initial hypothesis and provides a framework for understanding the conditions under which this hypothesis is applicable. Under optimal conditions, but without the assistance of any clamping system, our welded samples maintained a breaking resistance of up to 10.9 MPa. Full article

Illegal mining operations induce cascading ecosystem degradation by causing extensive ground subsidence, necessitating accurate underground goaf localization for effectively induced-hazard mitigation. The conventional locating method applied the synthetic aperture radar interferometry (InSAR) technique to obtain ground deformation to estimate underground goaf parameters, and the locating accuracy was crucially contingent upon the appropriateness of nonlinear deformation function models selection and the precision of geological parameters acquisition. However, conventional model-driven underground goaf locating frameworks often fail to sufficiently integrate prior geological information during the model selection process, potentially leading to increased positioning errors. In order to enhance the operational efficiency and locating accuracy of underground goaf, deformation model selection must be aligned with site-specific geological conditions under varying cases of prior information. To address these challenges, this study categorizes prior geological information into three different hierarchical levels (detailed, moderate, and limited) to systematically investigate the correlations between model selection and prior information. Subsequently, field validation was carried out by applying two different non-linear deformation function models, Probability Integral Model (PIM) and Okada Dislocation Model (ODM), with three different prior geological information conditions. The quantitative performance results indicate that, (1) under a detailed prior information condition, PIM achieves enhanced dimensional parameter estimation accuracy with 6.9% reduction in maximum relative error; (2) in a moderate prior information condition, both models demonstrate comparable estimation performance; and (3) for a limited prior information condition, ODM exhibits superior parameter estimation capability showing 3.4% decrease in maximum relative error. Furthermore, this investigation discusses the influence of deformation spatial resolution, the impacts of azimuth determination methodologies, and performance comparisons between non-hybrid and hybrid optimization algorithms. This study demonstrates that aligning the selection of deformation models with different types of prior geological information significantly improves the accuracy of underground goaf detection. The findings offer practical guidelines for selecting optimal models based on varying information scenarios, thereby enhancing the reliability of disaster evaluation and mitigation strategies related to illegal mining. Full article

Using waste biomass as a raw material for the combined production of electricity and heat offers corresponding energy, economic, environmental and resource efficiency benefits. The study examines both the performance of a system for combined energy production based on the Organic Rankine Cycle (ORC) utilizing wood biomass and the market interest in its deployment within Bulgaria. Its objective is to propose a technically and economically viable solution for the recovery of waste biomass through the combined production of electricity and heat while simultaneously assessing the readiness of industrial and municipal sectors to adopt such systems. The cogeneration plant incorporates an ORC module enhanced with three additional economizers that capture residual heat from flue gases. Operating on 2 t/h of biomass, the system delivers 1156 kW of electric power and 3660 kW of thermal energy, recovering an additional 2664 kW of heat. The overall energy efficiency reaches 85%, with projected annual revenues exceeding EUR 600,000 and a reduction in carbon dioxide emissions of over 5800 t/yr. These indicators can be achieved through optimal installation and operation. When operating at a reduced load, however, the specific fuel consumption increases and the overall efficiency of the installation decreases. The marketing survey results indicate that 75% of respondents express interest in adopting such technologies, contingent upon the availability of financial incentives. The strongest demand is observed for systems with capacities up to 1000 kW. However, significant barriers remain, including high initial investment costs and uneven access to raw materials. The findings confirm that the developed system offers a technologically robust, environmentally efficient and market-relevant solution, aligned with the goals of energy independence, sustainability and the transition to a low-carbon economy. Full article

This study investigates the role of Big Data Analytics Capabilities (BDACs) in ambidexterity explorative innovation (EXPLRI) and exploitative (EXPLOI) innovation for achieving a sustainable performance (SP) in the manufacturing sector of a resource-constrained developing economy. While a BDAC has been widely linked to innovation in developed economies, its effectiveness in developing contexts shaped by indigenous innovation practices like Jugaad remains underexplored. Anchored in the Resource-Based View (RBV) and Dynamic Capabilities (DC) theory, we propose a model where the BDAC enhances both EXPLRI and EXPLOI, which subsequently leads to an improved sustainable performance. We further examine the Jugaad capability as a cultural moderator. Using survey data from 418 manufacturing firms and analyzed via Partial Least Squares Structural Equation Modeling (PLS-SEM), results confirm that BDA capabilities significantly boost both types of innovations, which positively impact sustainable performance dimensions. Notably, Jugaad positively moderates the relationship between EXPLOI and financial, innovation, and operational performance but negatively moderates the link between EXPLRI and innovation performance. These findings highlight the nuanced influence of culturally embedded innovation practices in BDAC-driven ecosystems. This study contributes by extending the RBV–DC framework to include cultural innovation capabilities and empirically validating the contingent role of Jugaad in enhancing or constraining innovation outcomes. This study also validated the Jugaad capability measurement instrument for the first time in the context of Pakistan. For practitioners, aligning data analytics strategies with local innovative cultures is vital for sustainable growth in emerging markets. Full article

The safe and reliable operation of autonomous vehicles is contingent on comprehensive testing. However, the operational scenarios are inexhaustible. Corner cases, which critically influence autonomous vehicle safety, occur at an extremely low probability and follow a long-tail distribution. Corner cases can be defined as combinations of driving task and scenario elements. These scenarios are characterized by low probability, high risk, and a tendency to reveal functional limitations inherent to autonomous driving systems, triggering anomalous behavior. This study constructs a novel corner case dataset using naturalistic driving data, specifically tailored for autonomous vehicle testing. A scenario marginality quantification method is designed to analyze multi-source naturalistic driving data, enabling efficient extraction of corner cases. Heterogeneous scenarios are systematically transformed, resulting in a dataset characterized by diverse interaction behaviors and standardized formatting. The results indicate that the scenario marginality of the dataset constructed in this study is 2.78 times that of mainstream naturalistic driving datasets, and the scenarios exhibit considerable diversity. The trajectory and velocity fluctuations, quantified at 0.013 m and 0.021 m/s, respectively, are consistent with the kinematic characteristics of real-world driving scenarios. These results collectively demonstrate the dataset’s high marginality, diversity, and applicability. Full article

Palindromic antimicrobial peptides (PAMs) constitute versatile scaffolds for the design and optimization of anticancer agents with applications in therapy, diagnosis, and/or monitoring. In the present study, fluorolabeled peptides derived from the palindromic sequence RWQWRWQWR containing fluorescent probes, such as 2-Aminobenzoyl, 5(6)-Carboxyfluorescein, and Rhodamine B, were obtained. RP-HPLC analysis revealed that the palindromic peptide conjugated to Rhodamine B (RhB-RWQWRWQWR) exhibited the presence of isomers, likely corresponding to the open-ring and spiro-lactam forms of the fluorescent probe. This equilibrium is dependent on the peptide sequence, as the RP-HPLC analysis of dimeric peptide (RhB-RRWQWR-hF-KKLG)₂K-Ahx did not reveal the presence of isomers. The antibacterial activity of the fluorescent peptides depends on the probe attached to the sequence and the bacterial strain tested. Notably, some fluorescent peptides showed activity against reference strains as well as sensitive, resistant, and multidrug-resistant clinical isolates of E. coli, S. aureus, and E. faecalis. Fluorolabeled peptides 1-Abz (MIC = 62 µM), RhB-1 (MIC = 62 µM), and Abz-1 (MIC = 31 µM) exhibited significant activity against clinical isolates of E. coli, S. aureus, and E. faecalis, respectively. The RhB-1 (IC₅₀ = 61 µM), Abz-1 (IC₅₀ = 87 µM), and RhB-2 (IC₅₀ = 35 µM) peptides exhibited a rapid, significant, and concentration-dependent cytotoxic effect on HeLa cells, accompanied by morphological changes characteristic of apoptosis. RhB-1 (IC₅₀ = 18 µM) peptide also exhibited significant cytotoxic activity against breast cancer cells MCF-7. These conjugates remain valuable for elucidating the possible mechanisms of action of these novel anticancer peptides. Rhodamine-labeled peptides displayed cytotoxicity comparable to that of their unlabeled analogues, suggesting that cellular internalization constitutes a critical early step in their mechanism of action. These findings suggest that cell death induced by both unlabeled and fluorolabeled peptides proceeds predominantly via apoptosis and is likely contingent upon peptide internalization. Functionalization at the N-terminal end of the palindromic sequence can be evaluated to develop systems for transporting non-protein molecules into cancer cells. Full article

Background/Objective: The COVID-19 pandemic profoundly transformed social life worldwide, indiscriminately affecting individuals across all age groups. Children have not been exempted from the risk of severe illness and death caused by COVID-19. Objective: This paper sought to describe the clinical findings, laboratory and imaging results, and hospital care provided for severe and critical cases of COVID-19 in unvaccinated children, with or without severe asthma, hospitalized in a public referral service for COVID-19 treatment in the Brazilian state of Pernambuco. Methods: This was a case series study of severe and critical COVID-19 in hospitalized, unvaccinated children, with or without severe asthma, conducted in a public referral hospital between March 2020 and June 2021. Results: The case series included 80 children, aged from 1 month to 11 years, with the highest frequency among those under 2 years old (58.8%) and a predominance of males (65%). Respiratory diseases, including severe asthma, were present in 73.8% of the cases. Pediatric multisystem inflammatory syndrome occurred in 15% of the children, some of whom presented with cardiac involvement. Oxygen therapy was required in 65% of the cases, mechanical ventilation in 15%, and 33.7% of the children required intensive care in a pediatric intensive care unit. Pulmonary infiltrates and ground-glass opacities were common findings on chest X-rays and CT scans; inflammatory markers were elevated, and the most commonly used medications were antibiotics, bronchodilators, and corticosteroids. Conclusions: This case series has identified key characteristics of children with severe and critical COVID-19 during a period when vaccines were not yet available in Brazil for the study age group. However, the persistence of low vaccination coverage, largely due to parental vaccine hesitancy, continues to leave children vulnerable to potentially severe illness from COVID-19. These findings may inform the development of public health emergency contingency plans, as well as clinical protocols and care pathways, which can guide decision-making in pediatric care and ensure appropriate clinical management, ultimately improving the quality of care provided. Full article

This study investigates the critical capabilities and integration mechanisms that enable organizations to achieve substantive sustainability transformations. Using a mixed-methods approach combining survey data (n = 234), in-depth interviews (n = 42), and comparative case studies (n = 6), the research identifies how organizations effectively navigate sustainability paradoxes while developing integration practices that embed sustainability throughout organizational systems. Our research is primarily grounded in paradox theory, complemented by insights from organizational learning theory, institutional logics, and power dynamics perspectives to develop a comprehensive theoretical framework. Statistical analysis reveals strong relationships between paradox navigation capabilities and transformation outcomes (β = 0.31, p < 0.01), with integration practices emerging as the strongest predictor of sustainability success (β = 0.42, p < 0.01). Qualitative findings illuminate four essential integration mechanisms—governance integration, strategic integration, operational integration, and performance integration—and their temporal development. The significant interaction between power mobilization and integration practices (β = 0.19, p < 0.01) demonstrates that structural interventions are insufficient without attention to power relationships. The research contributes to sustainability science by advancing theory on paradoxical tensions in transformation processes, demonstrating how organizations can transcend the gap between sustainability rhetoric and substantive action through both structural integration and power-conscious approaches. By identifying contextual contingencies across sectors and organizational types, the study challenges universal prescriptions for sustainability transformation, offering instead a nuanced framework for creating organizational conditions conducive to context-specific transformation toward more sustainable futures. Our findings offer practical guidance for organizations navigating the complex landscape of sustainability transformation and contribute to the implementation of UN Sustainable Development Goals, particularly SDG 12 (Responsible Consumption and Production) and SDG 17 (Partnerships for the Goals). Full article

Numerous studies have demonstrated that in residential areas of Western cities, both luxury and legacy effects significantly shape tree species diversity dynamics. However, the specific mechanisms driving these diversity patterns in China, where urbanization has progressed at an unprecedented pace, remain poorly understood. In this study we selected 20 residential settlements and 7 key socio-economic properties to investigate the change trend of tree diversity (2006–2021) and its socio-economic driving factors in Beijing. Our results demonstrate significant increases in total, native, and exotic tree species richness between 2006 and 2021 (p < 0.05), with average increases of 36%, 26%, and 55%, respectively. Total and exotic tree Shannon-Wiener indices, as well as exotic tree Simpson’s index, were also significantly higher in 2021 (p < 0.05). Housing prices was the dominant driver shaping total and exotic tree diversity, showing significant positive correlations with both metrics. In contrast, native tree diversity exhibited a strong positive association with neighborhood age. Our findings highlight two dominant mechanisms: legacy effect, where older neighborhoods preserve native diversity through historical planting practices, and luxury effect, where affluent communities drive exotic species proliferation through ornamental landscaping initiatives. These findings elucidate the dual dynamics of legacy conservation and luxury-driven cultivation in urban forest development, revealing how historical contingencies and contemporary socioeconomic forces jointly shape tree diversity patterns in urban ecosystems. Full article

Academic English support is crucial for English as an Additional Language (EAL) nursing students in English-medium nursing education programmes. However, empirical research on content and language integrated learning (CLIL) within this specific context remains limited. This study, informed by recent advancements in translanguaging and trans-semiotising (TL-TS) theory, investigates the patterns of teacher collaboration in nursing CLIL and its impact when employing a TL-TS pedagogical approach. Analysis of students’ pre- and post-tests and multimodal classroom interactions reveals that effective collaboration between nursing specialists and language experts in CLIL can be fostered by (1) aligning with language education principles through the incorporation of internally persuasive discourse (IPD) about language learning and TL-TS practices; (2) simulating potential professional contingencies and co-developing coping strategies using TL-TS; and (3) elucidating nursing language norms through TL-TS and IPD. We advocate for re-imagination of CLIL in English-medium nursing education through an organistic–procedural TL perspective and highlight its potential to enhance EAL nursing students’ development of language proficiency and professional competencies. Full article

This study synthesizes the rapidly expanding evidence on how digital technologies reshape international trade, with a particular focus on small and medium-sized enterprises (SMEs). Guided by two research questions—(RQ1) How do digital tools influence the volume and composition of cross-border trade? and (RQ2) How do these effects vary by countries’ development level and firm size?—we conducted a PRISMA-compliant systematic literature review covering 2010–2024. Searches across eight major databases yielded 1857 records; after duplicate removal, title/abstract screening, full-text assessment, and Mixed Methods Appraisal Tool (MMAT 2018) quality checks, 86 peer-reviewed English-language studies were retained. Findings reveal three dominant technology clusters: (1) e-commerce platforms and cloud services, (2) IoT-enabled supply chain solutions, and (3) emerging AI analytics. E-commerce and cloud adoption consistently raise export intensity—doubling it for digitally mature SMEs—while AI applications are the fastest-growing research strand, particularly in East Asia and Northern Europe. However, benefits are uneven: firms in low-infrastructure settings face higher fixed digital costs, and cybersecurity and regulatory fragmentation remain pervasive obstacles. By integrating trade economics with development and SME internationalization studies, this review offers the first holistic framework that links national digital infrastructure and policy support to firm-level export performance. It shows that the trade-enhancing effects of digitalization are contingent on robust broadband penetration, affordable cloud access, and harmonized data-governance regimes. Policymakers should, therefore, prioritize inclusive digital-readiness programs, while business leaders should invest in complementary capabilities—data analytics, cyber-risk management, and cross-border e-logistics—to fully capture digital trade gains. This balanced perspective advances theory and practice on building resilient, equitable digital trade ecosystems. Full article

Color is a primary determinant of the value of jadeite jade, but the petrological provenance of the chromogenic elements of jadeite jade remains uncertain. The characteristics of the associated chromite in Myanmar jadeite jade were systematically investigated through a series of tests, including polarized microscopy, microarea X-ray fluorescence spectroscopy (micro-XRF) mapping, electron probe microanalysis (EPMA), and backscattered electron (BSE) imaging. The results demonstrate that the chromite composition in Myanmar jadeite jade is characterized by a high concentration of Cr₂O₃ (46.18–67.11 wt.%), along with a notable abundance of MnO (1.68–9.13 wt.%) compared with the chromite from the adjacent Myitkyina peridotite. The diffusion of chromium (Cr) and manganese (Mn) in jadeite jade is accomplished by accompanying the metamorphic pathway of Mn-rich chromite → kosmochlor → chromian jadeite → jadeite. In the subsequent phase of jadeite jade formation, the chromium-rich omphacite veins generated by the fluid enriched in Ca and Mg along the fissures of kosmochlor and chromian jadeite play a role in the physical diffusion of Cr and Mn. The emergence of the lavender hue in jadeite is contingent upon the presence of a relatively high concentration of Mn (approximately 100–1000 ppmw) and the simultaneous absence of Cr, which would otherwise serve as a more effective chromophore (no Cr or up to a dozen ppmw). The distinctive Mn-rich chromite represents the primary origin of the chromogenic element Cr (green) and, perhaps more notably, an overlooked provider of Mn (lavender) in Myanmar jadeite jade. Full article

In the context of small and medium-sized enterprises (SMEs), organizational resilience has emerged as a critical capability for navigating dynamic and turbulent environments. The ability of firms to sustain their performance despite external disruptions, particularly those arising from market and technological change, is paramount for achieving long-term sustainability. This study offers a novel contribution by examining how two key dimensions of environmental turbulence—market turbulence and technological turbulence—moderate the relationship between organizational resilience capacity and sustainability performance. Our empirical findings, based on data from 423 SMEs, demonstrate that while organizational resilience positively correlates with sustainability performance, this relationship is significantly weakened under high levels of market and technological turbulence, indicating a negative moderating effect. These results advance resource-based and dynamic capabilities theory by highlighting the contingent nature of resilience in unstable contexts. Furthermore, this study provides practical guidance. SMEs should strategically invest in resilience-building efforts and continuously adapt their strategies in response to environmental fluctuations. Targeted approaches to managing different forms of turbulence and forming resilience-oriented collaborations can enhance sustainability outcomes. This research makes significant contributions to theory and practice; however, there are limitations that future research should take into account in order to appropriately utilize this study’s findings. Full article

Power system infrastructure is exposed to a range of threats, including both naturally occurring events and intentional attacks. Traditional vulnerability assessment models, typically based on the N-1 criterion, do not account for the intentionality of disruptive agents. This paper presents a game-theoretic approach to protecting power system infrastructure against deliberate attacks, taking into account the effects of demand response. The interaction between the disruptive agent and the system operator is modeled as a leader–follower Stackelberg game. The leader, positioned in the upper-level optimization problem, must decide which elements to render out of service, anticipating the reaction of the follower (the system operator), who occupies the lower-level problem. The Stackelberg game is reformulated as a bilevel optimization model and solved using a metaheuristic approach. To evaluate the applicability of the proposed method, a 24-bus test system was employed. The results demonstrate that integrating demand response significantly enhances system resilience, compelling the disruptive agent to adopt alternative attack strategies that lead to lower overall disruption. The proposed model serves as a valuable decision-support tool for system operators and planners seeking to improve the robustness and security of electrical networks against disruptive agents. Full article

With good reason, Vatican II encourages the Eastern ecclesial realities to preserve and, if necessary, to rediscover their own traditions (also, even if not only, for ecumenical reasons). There are, however, certain aspects of the heritage of the Eastern Churches that require urgent revision in a spirit of consistency with the teachings of the Council. This is undoubtedly the case with regard to the anti-Jewish elements so specific to the entire Christian tradition (more or less generalised insults and judgments; substitutionary and appropriative perspectives; a purely instrumental use of the Jewish scriptures) and, in the absence of full reception of the Council, still reflected in the public prayers of the Romanian Greek-Catholic Church, to the detriment of that spirit of respect, fraternity, and dialogue theoretically embraced throughout the Catholic world today. In the light of Nostra aetate §4 and the subsequent developments that flowed from it, I shall try in this contribution to outline some possible criteria for reforming the offices of Holy Week, aiming to show that—at least in this particular case—it is not enough merely to refer to the OE, let alone to use it to justify a comfortable tendency towards inertia. Apart from the fact that it is this very Decree that speaks of a possible and necessary organic progress, we cannot ignore the more general spirit of renewal of the Council and its other documents (the NA, the SC, the DV, the GS). The challenge would be to engender a creative fidelity, which—while preserving the best of tradition—surpasses certain of its contingent elements. Full article