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21 pages, 29247 KB  
Article
Public Access Dimensions of Landscape Changes in Parks and Reserves: Case Studies of Erosion Impacts and Responses in a Changing Climate
by Shane Orchard, Aubrey Miller and Pascal Sirguey
GeoHazards 2026, 7(1), 12; https://doi.org/10.3390/geohazards7010012 - 15 Jan 2026
Viewed by 166
Abstract
This study investigates flooding and erosion impacts and human responses in Aoraki Mount Cook and Westland Tai Poutini national parks in Aotearoa New Zealand. These fast-eroding landscapes provide important test cases and insights for considering the public access dimensions of climate change. Our [...] Read more.
This study investigates flooding and erosion impacts and human responses in Aoraki Mount Cook and Westland Tai Poutini national parks in Aotearoa New Zealand. These fast-eroding landscapes provide important test cases and insights for considering the public access dimensions of climate change. Our objectives were to explore and characterise the often-overlooked role of public access as a ubiquitous concern for protected areas and other area-based conservation approaches that facilitate connections between people and nature alongside their protective functions. We employed a mixed-methods approach including volunteered geographic information (VGI) from a park user survey (n = 273) and detailed case studies of change on two iconic mountaineering routes based on geospatial analyses of digital elevation models spanning 1986–2022. VGI data identified 36 adversely affected locations while 21% of respondents also identified beneficial aspects of recent landscape changes. Geophysical changes could be perceived differently by different stakeholders, illustrating the potential for competing demands on management responses. Impacts of rainfall-triggered erosion events were explored in case studies of damaged access infrastructure (e.g., roads, tracks, bridges). Adaptive responses resulted from formal or informal (park user-led) actions including re-routing, rebuilding, or abandonment of pre-existing infrastructure. Three widely transferable dimensions of public access management are identified: providing access that supports the core functions of protected areas; evaluating the impacts of both physical changes and human responses to them; and managing tensions between stakeholder preferences. Improved attention to the role of access is essential for effective climate change adaptation in parks and reserves. Full article
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22 pages, 856 KB  
Article
Evaluating the Social Value of a Marine Plastics Upcycling Project in Japan
by Aya Yoshida, Yamato Hosoi, Masafumi Hagiwara, Shingo Kanezawa and Toshiya Kayama
Environments 2026, 13(1), 29; https://doi.org/10.3390/environments13010029 - 1 Jan 2026
Viewed by 662
Abstract
Marine plastic pollution poses severe ecological and economic threats, while people with disabilities (PwDs) often face limited meaningful employment opportunities. This study evaluated a unique social enterprise in Japan that addresses both challenges through upcycling marine plastic waste into accessories while providing employment [...] Read more.
Marine plastic pollution poses severe ecological and economic threats, while people with disabilities (PwDs) often face limited meaningful employment opportunities. This study evaluated a unique social enterprise in Japan that addresses both challenges through upcycling marine plastic waste into accessories while providing employment for PwDs. Using the Social Return on Investment (SROI) methodology, we assessed the project’s social and environmental impacts over one year (2020). Data was collected through stakeholder surveys, interviews, and operational records. The analysis identified 15 outcomes across six stakeholder groups, including income generation, environmental awareness-raising, and sustained volunteer engagement. The project achieved an SROI ratio of 3.50, indicating that every JPY 1 invested generated JPY 3.50 in social value. Media exposure (30.5%), employment income (25.6%), and volunteer motivation (18.5%) comprised 74% of the total value. Despite processing only 50 kg of marine plastic annually, the project demonstrated significant symbolic impact through behavior change and public awareness. Key challenges include limited production capacity, wage constraints, and gender-biased consumer demographics. This case illustrates how small-scale, community-based upcycling initiatives can generate multidimensional social value by integrating environmental conservation with social inclusion objectives. Full article
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16 pages, 2423 KB  
Article
Citizen Science for Assessment of Microplastics on Beaches: A Case Study in Mexico
by Ana Isabel Hernández-Soriano, Arely Areanely Cruz-Salas, Natalia Paulina Martínez-Toledo, Mariana Elizabeth Ballesteros-López, Alethia Vázquez-Morillas and Juan Carlos Alvarez-Zeferino
Microplastics 2025, 4(4), 105; https://doi.org/10.3390/microplastics4040105 - 11 Dec 2025
Viewed by 1005
Abstract
Microplastic pollution is a global environmental problem that affects marine and coastal ecosystems, and whose traditional monitoring is often expensive and limited in coverage. In this citizen science project, through the active participation of 26 local volunteers, data were gathered on the abundance [...] Read more.
Microplastic pollution is a global environmental problem that affects marine and coastal ecosystems, and whose traditional monitoring is often expensive and limited in coverage. In this citizen science project, through the active participation of 26 local volunteers, data were gathered on the abundance and types of microplastics present on various Mexican beaches, while also promoting public awareness. Participants received materials and basic training to identify and collect microplastics using a standardized methodology, which enabled the creation of a broad and representative database consisting of 63 samples from 42 different beaches. A total of 1500 particles were collected, of which 75.13% were microplastics. The average success rate in collecting microplastics among the volunteers was 63.7 ± 34.7%. The results revealed a considerable diversity of microplastics in the studied areas, with a mean concentration of 3.5 MP/m ± 3.4 MP/m, fragments as the most common type identified (45% of the total), white as the predominant color (43%) and polyethylene as the polymer with the highest proportion (31%). This citizen science approach proved to be an effective tool for environmental monitoring, as the median value of correct identification of microplastics in this study was 80%. This method facilitates large-scale data collection and contributes to community engagement in marine conservation. Moreover, although it needs improvement, the advantages of this methodology are evident in its ability to complement traditional scientific studies and support more informed and participatory public policies in plastic waste management. Full article
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14 pages, 8477 KB  
Article
Reestablishment and Conservation Implications of the Milu Deer Population in Poyang Lake
by Zhibin Cheng, Zhenyu Zhong, Bin Xiong, Xinghua Zhong, Jialiang Ma, Daoli Liu, Chenmiao Feng, Qingyun Guo, Qingxun Zhang, Jiade Bai and Kun Cheng
Animals 2025, 15(23), 3446; https://doi.org/10.3390/ani15233446 - 29 Nov 2025
Viewed by 493
Abstract
Reintroduction has been recognized as a vital approach to protecting and restoring wild populations of rare and endangered species. Although numerous reintroduction programs have been launched worldwide, in-depth studies on population establishment, dynamics, distribution patterns, and challenges remain limited. The Milu (Elaphurus [...] Read more.
Reintroduction has been recognized as a vital approach to protecting and restoring wild populations of rare and endangered species. Although numerous reintroduction programs have been launched worldwide, in-depth studies on population establishment, dynamics, distribution patterns, and challenges remain limited. The Milu (Elaphurus davidianus), endemic to China and once declared Extinct in the Wild by the IUCN, has become one of the most successful examples of global endangered species reintroduction since the initiation of its recovery program in 1985. Focusing on the reintroduction project in the Poyang Lake basin—China’s largest freshwater lake—this study analyzed 14 years of monitoring data to examine the processes of population re-establishment, demographic trends, and spatiotemporal distribution of the species, while also identifying major ongoing challenges. Findings reveal the following: (1) the acclimatization process was essential for 10 individuals first reintroduced in 2013, and then 30 individuals joined to the growing population, followed by the largest-scale release of 47 in 2018, which finally led to eight consecutive years of natural reproduction, with a theoretically estimated population of 89 individuals until August 2025; (2) among 1697 individual sightings in 238 monitoring events, 952 records can be distinguished between male and female individuals (sex ratio = 1:1.63), yielding a mean herd size of 7.28 ± 0.68 individuals per sighting event—although numbers rose slightly in 2024, a declining trend was observed from 2019 to 2023 (from 11.26 to 5.13); (3) the Milu have expanded their range across eastern Poyang Lake, demonstrating a behavioral patterns of migrating out of the lake zone during flood seasons and returning in dry season; (4) the restoration of the Milu population is a systematic endeavor, in which government support and the participation of conservation professionals, scientists, volunteers, media, and the public are critical factors; and (5) ongoing threats such as human disturbance (e.g., habitat degradation) and climate change continue to jeopardize long-term population viability. This study offers important scientific insights into the recovery of endangered wildlife globally and underscores the essential role of governmental commitment, long-term monitoring, and multi-stakeholder collaboration in species reintroduction efforts. Full article
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15 pages, 944 KB  
Article
Key Factors Influencing Volunteer Engagement in Grassland Burning Activities Conducted by Pastoral Associations: A Case Study of Aso-Kujyu National Park
by Momoko Mogi, Yuuto Okuyama, Reiko Machida, Hijiri Shimojima and Thomas Jones
Conservation 2025, 5(4), 60; https://doi.org/10.3390/conservation5040060 - 20 Oct 2025
Viewed by 675
Abstract
In Aso Kujyu National Park, grassland landscapes are being conserved through volunteer activities to support controlled burns of fields, and the current status of grasslands is being assessed through surveys of natural resources. In discussing the continuation of grassland management in the future, [...] Read more.
In Aso Kujyu National Park, grassland landscapes are being conserved through volunteer activities to support controlled burns of fields, and the current status of grasslands is being assessed through surveys of natural resources. In discussing the continuation of grassland management in the future, it is necessary to investigate the reasons and factors that lead pastoral associations to request volunteers for managed burning. On the other hand, there are no studies on the reasons why pastoral associations choose to request volunteers to support controlled burns, or the factors behind this choice. Thus, to support multi-stakeholder management of national parks, this study investigates the mechanisms of volunteer engagement in pastoral-led prescribed burning initiatives in Aso Kujyu National Park and key drivers facilitating their engagement involvement. A questionnaire survey was conducted among 161 pastoral associations in the Aso area regarding the introduction of volunteers to support controlled burns. A total of 52 associations responded to the survey, corresponding to a 32% response rate. The results of a discriminant analysis revealed that the pastoral cooperatives that had introduced volunteers did not have enough workers and did not oppose the participation of outsiders, while those that had not employed volunteers had a sufficient number of workers and felt resistance towards the participation of outsiders. Full article
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14 pages, 511 KB  
Article
Body Temperature, Metabolic, and Circulatory Changes After 8 Days of Water-Only Fasting in Healthy Middle-Aged Men
by Ilona Pokora, Piotr Wyderka, Wiesław Pilis and Karol Pilis
J. Clin. Med. 2025, 14(16), 5735; https://doi.org/10.3390/jcm14165735 - 13 Aug 2025
Viewed by 3935
Abstract
Background: Maintaining thermal homeostasis is a basic function of the human body. This homeostasis depends largely on the body’s nutritional status and other conditions related to it. Aim: The present study investigated the impact of 8 days of water-only fasting (8DW-F) on selected [...] Read more.
Background: Maintaining thermal homeostasis is a basic function of the human body. This homeostasis depends largely on the body’s nutritional status and other conditions related to it. Aim: The present study investigated the impact of 8 days of water-only fasting (8DW-F) on selected features of thermal homeostasis, taking into account somatic, metabolic, and circulatory changes in middle-aged men. Methods: A total of 13 healthy men took part in the experiment. Volunteers were examined twice: after a mixed diet (C) and after using 8DW-F. At baseline, the following were recorded: body mass (BM), body fat (FM), fat-free mass (FFM), and total water (TBW), along with basal metabolic rate (BMR) and body surface area (BSA). Then, after 30 min of sitting under thermoneutral conditions, the following measurements were taken: eardrum temperature (Ti), skin temperatures (Tsk), heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), oxygen uptake (VO2), and respiratory exchange ratio (RER). The following were then calculated: average body (MTB) and skin temperature (MTsk), resting metabolic rate (RMR), body to skin temperature gradient (g), and whole-body thermal conductivity (C). Results: The results showed that 8DW-F cause a significant reduction in most somatic variables as well as SBP and BMR (p < 0.001), RMR (p < 0.05) with no changes in Ti, MTsk, MTB, or C and g (p = 0.09). There were also significant correlations between Δ MTB × Δ BMR (p < 0.05) and Δ RMR × Δ VO2 (p < 0.001). Moreover, changes in the C range correlated with Δ RMR (p < 0.005) and Δ DBP (p < 0.05). Conclusions: 8DW-F reduced resting metabolic heat production in the studied men, but sufficient heat conservation ensured that thermal homeostasis was maintained under thermally neutral conditions. Full article
(This article belongs to the Section Sports Medicine)
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22 pages, 766 KB  
Article
Predicting GPS Use Among Visitors in Capçaleres del Ter i del Freser Natural Park (Catalonia, Spain)
by Sara Hamza-Mayora, Estela Inés Farías-Torbidoni and Demir Barić
Tour. Hosp. 2025, 6(3), 137; https://doi.org/10.3390/tourhosp6030137 - 12 Jul 2025
Viewed by 1025
Abstract
The increasing use of Global Positioning System (GPS) tools reshapes nature-based recreational practices. While previous research has examined the role of GPS technologies in outdoor recreation, limited attention has been given to the specific factors driving GPS use in nature-based settings such as [...] Read more.
The increasing use of Global Positioning System (GPS) tools reshapes nature-based recreational practices. While previous research has examined the role of GPS technologies in outdoor recreation, limited attention has been given to the specific factors driving GPS use in nature-based settings such as natural parks. This case study examines the sociodemographic, behavioural, motivational and experiential factors influencing GPS use among visitors to the Capçaleres del Ter i del Freser Natural Park (Catalonia, Spain). A structured visitor survey (n = 999) was conducted over a one-year period and a hierarchical binary logistic regression model was applied to evaluate the explanatory contribution of four sequential variable blocks. The results showed that the behavioural factors (i.e., physical activity intensity) emerged as the strongest predictor of GPS use. Additionally, the final model demonstrated that visitors who were younger, engaged in higher-intensity physical activities, motivated by health-related goals, undertook longer routes, and reported more positive experiences were significantly more likely to use GPS tools during their visit. These findings highlight the need to adapt communication strategies to diverse visitor profiles and leverage volunteered geographic information (VGI) for improved visitor monitoring, flow management, and adaptive conservation planning. Full article
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15 pages, 262 KB  
Article
Volunteering in Environmental Organizations and Subjective Well-Being: Evidence from a Nationally Representative, Longitudinal Dataset in the US
by Onur Sapci, Aliaksandr Amialchuk and Jon D. Elhai
World 2025, 6(3), 94; https://doi.org/10.3390/world6030094 - 4 Jul 2025
Viewed by 2642
Abstract
This study uses a nationally representative longitudinal dataset in the US to examine the long-term association of volunteering for environmental, recycling, and conservation groups with a person’s (a) willingness to continue to volunteer later in life and (b) several measures of their mental [...] Read more.
This study uses a nationally representative longitudinal dataset in the US to examine the long-term association of volunteering for environmental, recycling, and conservation groups with a person’s (a) willingness to continue to volunteer later in life and (b) several measures of their mental and physical well-being including perceived social status, optimism, psychological stress, suicidal thoughts and attempts, depressive symptoms and general self-reported physical health. By using Add Health data, we match responses to an environmental volunteerism question in Wave III (2002) with subjective well-being responses in Wave V (2016–2018) to examine the long-term association between these variables. After excluding missing responses, the analysis sample consists of 9800 individuals. After using linear survey regression analyses and several techniques based on propensity scores (stratification, weighting, matching) two key results emerged: first, being involved in environmental groups and organizations early in life showed a significant positive association with more hours spent on volunteering or community service work later in life; and second, people who volunteer in early adulthood are more optimistic, more sociable, have a higher perceived social status, display less stress and depressive symptoms. Full article
24 pages, 757 KB  
Review
Citizen Science for Soil Monitoring and Protection in Europe: Insights from the PREPSOIL Project Under the European Soil Mission
by Karel Charvát, Jaroslav Šmejkal, Petr Horák, Markéta Kollerová, Šárka Horáková and Pierre Renault
Sustainability 2025, 17(11), 5042; https://doi.org/10.3390/su17115042 - 30 May 2025
Cited by 1 | Viewed by 1757
Abstract
Citizen science (CS) is increasingly recognized as a complementary approach for addressing soil health challenges—including erosion, pollution, nutrient imbalances, and biodiversity loss—by harnessing public participation to broaden spatial and temporal data collection. This review synthesizes findings from the following: (i) a systematic analysis [...] Read more.
Citizen science (CS) is increasingly recognized as a complementary approach for addressing soil health challenges—including erosion, pollution, nutrient imbalances, and biodiversity loss—by harnessing public participation to broaden spatial and temporal data collection. This review synthesizes findings from the following: (i) a systematic analysis of peer-reviewed literature and grey sources, (ii) a database of 96 CS initiatives compiled by the European PREPSOIL project, and (iii) questionnaire surveys and workshops conducted in five Living Labs across Europe. Our analysis indicates that volunteer-driven monitoring can enhance the volume and granularity of soil data, providing critical insights into parameters such as organic carbon content, nutrient levels, and pollutant concentrations. However, persistent challenges remain, including inconsistencies in data validation, volunteer attrition, and concerns regarding digital literacy and data privacy. Despite these challenges, ongoing efforts to standardize protocols, integrate remote sensing and sensor-based validation methods, and employ feedback mechanisms improve data reliability and participant engagement. We conclude that sustained capacity-building, transparent data governance, and stakeholder collaboration, from local communities to governmental bodies, are essential for fully realizing the potential of citizen science in soil conservation. This work is framed within the context of the European Soil Mission, and CS is demonstrated to meaningfully support sustainable land management and evidence-based policymaking by aligning public-generated observations with established scientific frameworks. Full article
(This article belongs to the Special Issue Sustainable Land Use and Management, 2nd Edition)
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29 pages, 31652 KB  
Article
Low-Carbon Practices and Cultural Adaptation Among Older Chinese Migrants: Insights from Walking Interviews on Environmental Policy and Social Integration
by Qing Ni, Hua Dong and Antonios Kaniadakis
Int. J. Environ. Res. Public Health 2025, 22(6), 832; https://doi.org/10.3390/ijerph22060832 - 25 May 2025
Cited by 1 | Viewed by 1225
Abstract
This study employs walking interviews to examine the low-carbon practices, cultural adaptation, and policy awareness of older Chinese migrants in the UK within their everyday environments. A total of 20 participants were interviewed in public spaces such as parks, supermarkets, and their homes. [...] Read more.
This study employs walking interviews to examine the low-carbon practices, cultural adaptation, and policy awareness of older Chinese migrants in the UK within their everyday environments. A total of 20 participants were interviewed in public spaces such as parks, supermarkets, and their homes. Using contextual thematic analysis, the study identifies key factors influencing their environmental behaviors. The findings reveal the following: (1) Language barriers, economic pressures, and social isolation limit migrants’ understanding of environmental policies. Many participants rely on self-sufficient ethnic community networks rather than engaging with mainstream sources; (2) Generational differences are evident—younger migrants demonstrate greater theoretical awareness of environmental policies, whereas older migrants exhibit stronger low-carbon behaviors through energy conservation and waste reduction; (3) A balance between cultural identity and consumption habits—while some migrants adjust their dietary, spending, and linguistic habits, core cultural values such as frugality and family responsibility remain unchanged. This study highlights the value of walking interviews in capturing situational insights into low-carbon behaviors and cultural adaptation. It provides empirical evidence for government agencies and community organizations, advocating for cross-cultural environmental education and improved policy communication. Recommendations include targeted environmental training, community-based volunteer initiatives, intergenerational environmental education, and policy dissemination through WeChat, Chinese communities, and ethnic networks. These measures can help bridge the generational gap in policy awareness and promote social integration among older Chinese migrants. Full article
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19 pages, 12475 KB  
Article
Pursuing Ecological and Social Co-Benefits: Public Hierarchical Willingness for Biodiversity Conservation in Urban Parks
by Minli Jin, Lihui Hu, Guang Hu and Jing Guo
Sustainability 2025, 17(9), 4201; https://doi.org/10.3390/su17094201 - 6 May 2025
Cited by 2 | Viewed by 1494
Abstract
Urban green spaces play a critical role in sustaining the urban park biodiversity. The relationship between biodiversity and city residents is complex. Understanding the cognitive preferences of residents toward biodiversity is vital for effective conservation. This study investigated the public willingness to protect [...] Read more.
Urban green spaces play a critical role in sustaining the urban park biodiversity. The relationship between biodiversity and city residents is complex. Understanding the cognitive preferences of residents toward biodiversity is vital for effective conservation. This study investigated the public willingness to protect the biodiversity in urban parks using questionnaire-based assessments and explored the underlying drivers. The study focused on the residents of Hangzhou, China, and analyzed the effects of respondent and visit characteristics as well as their interactions using ANOVA, PERMANOVA, GLM, and NMDS. The visitor age, education level, satisfaction with plant landscapes, and visit frequency significantly influenced their willingness to conserve. Based on a “cognitive-experience-investment” framework, we uncovered (1) positive synergistic effects between urban park biodiversity and the abundance of urban green space fauna; (2) threshold constraints linking volunteer time for biodiversity conservation and economic expenditures on biodiversity-friendly products; and (3) the complex interactions among these factors. The findings not only elucidate the driving mechanisms and model optimization pathways associated with public willingness for conserving urban biodiversity but also provide actionable strategies to promote both ecological conservation and societal wellbeing. Full article
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16 pages, 1926 KB  
Article
Contribution of Citizen Science Data on the Evaluation of Local Biodiversity of Benthic Macroinvertebrate Communities
by Alessandro Lagrotteria, Samuele Roccatello and Alberto Doretto
Ecologies 2025, 6(2), 31; https://doi.org/10.3390/ecologies6020031 - 2 Apr 2025
Cited by 1 | Viewed by 1619
Abstract
Citizen science is increasingly utilized for environmental monitoring and educational purposes. For lotic ecosystems, this approach could be used to implement traditional methods and gain more data on local biodiversity, particularly in areas where professional monitoring is limited. This study, conducted in Italy, [...] Read more.
Citizen science is increasingly utilized for environmental monitoring and educational purposes. For lotic ecosystems, this approach could be used to implement traditional methods and gain more data on local biodiversity, particularly in areas where professional monitoring is limited. This study, conducted in Italy, aimed to complement data on river macroinvertebrates collected by the Regional Environmental Protection Agency (ARPA) with additional data gained by volunteers. Our results revealed taxonomic differences between the macroinvertebrate communities of ARPA and citizen science sites. ARPA sites host 34.4% of the total biodiversity, with 22 exclusive taxa, while citizen science sites, with 6 exclusive taxa, represent 9.4% of the total gamma diversity. Compositional differences are mainly explained by taxa turnover between sites. ARPA sites, located along the main river stretches, are richer in alpha and gamma diversity, while volunteer-monitored sites, mostly in agricultural ditches, show lower richness at the local and regional scales but host some unique taxa, increasing the total biodiversity. This study supports the implementation of volunteer programs to increase the number of monitored rivers, enhancing information on macroinvertebrate diversity and distribution and generating relevant data to support decision-making and develop strategies for river conservation and ecosystem restoration at a local scale. Full article
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16 pages, 775 KB  
Article
Predictors for Poor Outcomes at Six Months on Pain, Disability, Psychological and Health Status in Greek Patients with Chronic Low Back Pain After Receiving Physiotherapy: A Prospective Cohort Study
by Matthaios Petrelis, Georgios Krekoukias, Ioannis Michopoulos, Vasileios Nikolaou and Konstantinos Soultanis
Clin. Pract. 2025, 15(3), 63; https://doi.org/10.3390/clinpract15030063 - 16 Mar 2025
Viewed by 2372
Abstract
Background: Although previous studies have suggested a variety of sociodemographic and psychological factors as predictors of poor outcomes in patients with chronic low back pain (CLBP), longitudinal studies remain rare. Objectives: To examine the prognostic indicators for poor outcome at 6 months [...] Read more.
Background: Although previous studies have suggested a variety of sociodemographic and psychological factors as predictors of poor outcomes in patients with chronic low back pain (CLBP), longitudinal studies remain rare. Objectives: To examine the prognostic indicators for poor outcome at 6 months on pain, disability, quality of life, anxiety, depression and somatic symptom disorders (SSDs) in Greek backache patients and to evaluate the medium-term effects of a conservative physiotherapeutic approach (massage, ultrasound, transcutaneous electrical nerve stimulation, low-level laser and exercise program). Methods: A prospective cohort study of 145 volunteers receiving treatment for CLBP in a physiotherapy unit was conducted using random systematic sampling. The intervention was assessed by comparing pre-treatment, post-treatment and six-month measurements with Friedman’s test and the Bonferroni correction, using the pain numerical rating scale (PNRS), Roland–Morris disability questionnaire (RMDQ), EuroQol-5-dimension-5-level (EQ-5D-5L), Hospital Anxiety and Depression Scale (HADS) and Somatic Symptom Scale-8 (SSS-8). Multiple linear regression analysis was carried out to determine the impact of demographics and pre-treatment scores with scores at six months. Results: The mean age was 60.6 years (±14.7). Post-treatment, statistically significant improvements were observed across all outcome measures, including PNRS, RMDQ, EQ-5D-5L and SSS-8 (all p ≤ 0.001), with anxiety showing a notable reduction (p = 0.002). After examining the multiple regression analysis, pre-treatment SSS-8 emerged as a predictor of elevated levels of pain, disability, anxiety and depression at 6 months. Conclusions: The findings yielded not only somatic symptom burden, greater age and pain intensity as prognostic indicators for poor outcomes at six months, but also reported favorable medium-term effects for a conventional physiotherapy regimen in CLBP management, as well. Full article
(This article belongs to the Special Issue Musculoskeletal Pain and Rehabilitation)
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13 pages, 2254 KB  
Article
Awareness and Behaviors of Beijing Residents Regarding Wetland Conservation
by Lichun Mo and Botao Yan
Water 2025, 17(3), 375; https://doi.org/10.3390/w17030375 - 30 Jan 2025
Viewed by 1516
Abstract
Wetlands are among the most important ecosystems worldwide, playing an irreplaceable role in maintaining ecological balance and ensuring human well-being. This study conducted a questionnaire survey of 1008 residents across 16 districts in Beijing to systematically analyze their awareness, attitudes, and behaviors regarding [...] Read more.
Wetlands are among the most important ecosystems worldwide, playing an irreplaceable role in maintaining ecological balance and ensuring human well-being. This study conducted a questionnaire survey of 1008 residents across 16 districts in Beijing to systematically analyze their awareness, attitudes, and behaviors regarding wetland conservation. The results indicate that the majority of residents hold a positive attitude towards wetland conservation, with over 90% supporting the expansion of wetland areas and 82% considering wetland protection more important than economic development. Regarding willingness to pay, residents tend to prefer small donations, with the highest proportion willing to contribute less than CNY 100 annually, while 92.5% expressed a willingness to support wetland conservation through volunteer work. Residents’ behaviors are significantly influenced by the geographical location and functional configuration of wetlands, with higher visit rates observed at wetlands closer to urban areas, such as Shichahai Wetland and Summer Palace Wetland. This study also reveals that public awareness of wetland ecological functions is lacking, particularly in terms of biodiversity conservation and water quality improvement. The findings provide a scientific basis for enhancing wetland conservation policies and improving public awareness and actions for wetland protection in Beijing. Full article
(This article belongs to the Special Issue Wetland Conservation and Ecological Restoration)
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12 pages, 517 KB  
Study Protocol
Safety, Tolerability, and Immunogenicity of the InvaplexAR-Detox Shigella Vaccine Co-Administered with the dmLT Adjuvant in Dutch and Zambian Adults: Study Protocol for a Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Phase Ia/b Clinical Trial
by Geert V. T. Roozen, Nsofwa Sukwa, Masuzyo Chirwa, Jessica A. White, Marcus Estrada, Nicole Maier, Kevin R. Turbyfill, Renee M. Laird, Akamol E. Suvarnapunya, Aicha Sayeh, Flavia D’Alessio, Candice Marion, Laura Pattacini, Marie-Astrid Hoogerwerf, Rajagopal Murugan, Manuela Terrinoni, Jan R. Holmgren, Sodiomon B. Sirima, Sophie Houard, Michelo Simuyandi and Meta Roestenbergadd Show full author list remove Hide full author list
Vaccines 2025, 13(1), 48; https://doi.org/10.3390/vaccines13010048 - 8 Jan 2025
Cited by 3 | Viewed by 2286
Abstract
Background: Shigella infections remain endemic in places with poor sanitation and are a leading cause of diarrheal mortality globally, as well as a major contributor to gut enteropathy and stunting. There are currently no licensed vaccines for shigellosis but it has been estimated [...] Read more.
Background: Shigella infections remain endemic in places with poor sanitation and are a leading cause of diarrheal mortality globally, as well as a major contributor to gut enteropathy and stunting. There are currently no licensed vaccines for shigellosis but it has been estimated that an effective vaccine could avert 590,000 deaths over a 20-year period. A challenge to effective Shigella vaccine development has been the low immunogenicity and protective efficacy of candidate Shigella vaccines in infants and young children. Additionally, a new vaccine might be less immunogenic in a highly endemic setting compared to a low endemic setting (“vaccine hyporesponsiveness”). The use of a potent adjuvant enhancing both mucosal and systemic immunity might overcome these problems. InvaplexAR-Detox is an injectable Shigella vaccine that uses a novel combination of conserved invasion plasmid antigen proteins and a serotype-specific bacterial lipopolysaccharide attenuated for safe intramuscular administration. The adjuvant dmLT has been shown to enhance Shigella immune responses in mice, has safely been administered intramuscularly, and was shown to enhance immune responses in healthy volunteers when given in combination with other antigens in phase I trials. This article describes the protocol of a study that will be the first to assess the safety, tolerability, and immunogenicity of InvaplexAR-Detox co-administered with dmLT in healthy adults in low-endemic and high-endemic settings. Methods: In a multi-center, randomized, double-blind, and placebo-controlled dose-escalation phase Ia/b trial, the safety, tolerability, and immunogenicity of three intramuscular vaccinations administered 4 weeks apart with 2.5 µg or 10 µg of InvaplexAR-Detox vaccine, alone or in combination with 0.1 µg of the dmLT adjuvant, will first be assessed in a total of 50 healthy Dutch adults (phase Ia) and subsequently in 35 healthy Zambian adults (phase Ib) aged 18–50 years. The primary outcome is safety, and secondary outcomes are humoral and cellular immune responses to the adjuvanted or non-adjuvanted vaccine. Discussion: This trial is part of the ShigaPlexIM project that aims to advance the early clinical development of an injectable Shigella vaccine and to make the vaccine available for late-stage clinical development. This trial addresses the issue of hyporesponsiveness in an early stage of clinical development by testing the vaccine and adjuvant in an endemic setting (Zambia) after the first-in-human administration and the dose-escalation has proven safe and tolerable in a low-endemic setting (Netherlands). Besides strengthening the vaccine pipeline against a major diarrheal disease, another goal of the ShigaPlexIM project is to stimulate capacity building and strengthen global North-South relations in clinical research. Trial registration: EU CT number: 2023-506394-35-02, ClinicalTrials.gov identifier: NCT05961059. Full article
(This article belongs to the Special Issue Recent Scientific Advances in Vaccines for Shigella)
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