Leishmania are an understudied genus of parasitic protozoans causing significant health problems for people, particularly in tropical climates. To better understand the growth of Leishmania and potential drug sensitivity implications, the effects of...
Background and Objectives: Optimization of chemotherapy is crucial for cancer patients. Timely and costly efficient treatments are emerging due to the increasing incidence of cancer worldwide. Here, we present a methodology of nano-motion analysis th...
Continuous passive motion (CPM) is widely used after total knee replacement. In this study, we investigated the effect of CPM combined with cell-based construct-transplantation in osteochondral tissue engineering. We created osteochondral defects (3...
We performed a time-lapse imaging with atomic force microscopy (AFM) of the motion of eukaryotic CRFK (Crandell-Rees Feline Kidney) cells adhered onto a glass surface and anchored to other cells in culture medium at 37 °C. The main finding is a g...
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that play an important role in signal transduction at the neuromuscular junction (NMJ). Movement of the nAChR extracellular domain following agonist binding induces conformation...
This paper presents an experimental Synthetic Aperture Radar (SAR) system that is under development in the Universidad Politécnica de Madrid. The system uses Linear Frequency Modulated Continuous Wave (LFM-CW) radar with a two antenna configuration f...
Aging is a progressive functional decline in organs and tissues over time and typically represents the accumulation of psychological and social changes in a human being. Diverse diseases, such as cardiovascular, musculoskeletal, and neurodegenerative...
The visual system plays a vital role in the daily life of humans, as more than 90 percent of the external information received by the human brain throughout the day comes from the visual system. However, how the human brain processes the received vis...
The movement of proteins through the cell membrane is essential for cell-to-cell communication, which is a process that allows the body’s immune system to identify any foreign cells, such as cells from another organism and pathogens; this movem...
Aiming at the problem that unmanned surface vehicle (USV) motion planning is disturbed by effects of wind and current, a USV motion planning method based on regularization-trajectory cells is proposed. First, a USV motion mathematical model is establ...
Serotonin receptors play important roles in neuronal excitation, emotion, platelet aggregation, and vasoconstriction. The serotonin receptor subtype 2A (5-HT2AR) is a Gq-coupled GPCR, which activate phospholipase C. Although the structures and functi...
Experiments to measure a single molecule/particle, i.e., an individual molecule/particle, at room temperature or under physiological conditions without immobilization—for example, on a surface or without significant hydrodynamic flow—have...
Lq (0 < q ≤ 1) regularization has been confirmed effective when applied to sparse SAR imaging. However, the inaccuracies caused by motion errors in the observation model will lead to various degradations and defocus in the reconstructed image....
Some fundamental visual features have been found to be fully extracted before reaching the cerebral cortex. We focus on direction-selective ganglion cells (DSGCs), which exist at the terminal end of the retinal pathway, at the forefront of the visual...
This study investigates the 3RPUR (3-Revolute–Prismatic–Universal–Revolute) variable parallel mechanism, employing screw theory and linear geometry to analyze the geometric relationships and constraint characteristics of the RPUR (R...
The visual system of sighted animals plays a critical role in providing information about the environment, including motion details necessary for survival. Over the past few years, numerous studies have explored the mechanism of motion direction dete...
The objective was to investigate the impacts of the robot’s dynamic affective expressions in task-related scenarios on human–robot collaboration (HRC) and performance in human–robot collaborative assembly tasks in flexible manufactu...
How specific features of the environment are represented in the mammalian brain is an important unexplained mystery in neuroscience. Visual information is considered to be captured most preferentially by the brain. As one of the visual information el...
Cardiovascular diseases are a leading global cause of mortality. The current standard diagnostic methods, such as imaging and invasive procedures, are relatively expensive and partly connected with risks to the patient. Bioimpedance measurements hold...
The complexity and functional evolution of mammalian visual systems have always been a focal point in neuroscience and biological science research. The primary neurons that output motion direction signals have been a focal point of research in visual...
MET sensors for measuring motion parameters are used in many scientific and technical fields. Meanwhile, the geometries of the transforming cell applied practically are far from optimal, and the influence of many geometric parameters on the sensitivi...
Background/Objectives:Porphyromonas gingivalis infection has been associated with various systemic diseases and may cause delayed healing of muscle injury. However, the relationship between muscle injury healing and P. gingivalis infection remains un...
Enhancing treatment of locally advanced non-small cell lung cancer (LA-NSCLC) by using pencil beam scanning proton therapy (PBS-PT) is attractive, but little knowledge exists on the effects of uncertainties occurring between the planning (Plan) and t...
The internal organ at risk volume (IRV) concept might improve toxicity profiles in stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC). We studied (1) clinical aspects in central vs. peripheral tumors, (2) the IRV concep...
A thorough understanding of the inhalation dynamics of infectious aerosols indoors and infection dynamics within the host by inhaled viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays an important role in the assessmen...
The lensless imaging technique, which integrates a microscope into a complementary metal oxide semiconductor (CMOS) digital image sensor, has become increasingly important for the miniaturization of biological microscope and cell detection equipment....
Diffuse type tenosynovial giant cell tumor (D-TGCT) of the knee presents with stiffness, pain and swelling with surgery being the mainstay treatment. However, the literature lacks data on clinical course of range of motion, pain (ROM), and swelling a...
The present work is focused on a detailed description of an in-house, particle-in-cell code developed by the authors, whose main aim is to perform highly accurate plasma simulations on an off-the-shelf computing platform in a relatively short computa...
This study aims to investigate the correlation between intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) parameters in magnetic resonance imaging (MRI) and programmed death-ligand 1 (PD-L1) expression in non-small cell lung cancer (N...
Precisely controlling magnetically tagged cells in a complex environment is crucial to constructing a magneto-microfluidic platform. We propose a two-dimensional model for capturing magnetic beads from non-magnetic fluids under a micromagnetic matrix...
Intracytoplasmic sperm injection (ICSI) is an infertility treatment where a single sperm is immobilised and injected into the egg using a glass injection pipette. Minimising vibration in three orthogonal axes is essential to have precise injector mot...
Previous studies have reported that directionally selective ganglion cells respond strongly in their preferred direction, but are only weakly excited by stimuli moving in the opposite null direction. Various studies have attempted to elucidate the me...
Motion direction detection is an essential task for both computer vision and neuroscience. Inspired by the biological theory of the human visual system, we proposed a learnable horizontal-cell-based dendritic neuron model (HCdM) that captures motion...
Deterministic lateral displacement (DLD) technology has great potential for the separation, enrichment, and sorting of red blood cells (RBCs). This paper presents a numerical simulation of the motion of RBCs using DLD devices with different pillar sh...
Recognition of body posture and motion is an important physiological function that can keep the body in balance. Man-made motion sensors have also been widely applied for a broad array of biomedical applications including diagnosis of balance disorde...
In 3D motion capture, multiple methods have been developed in order to optimize the quality of the captured data. While certain technologies, such as inertial measurement units (IMU), are mostly suitable for 3D orientation estimation at relatively hi...
A variety of biological and pharmaceutical studies, such as for anti-cancer drugs, require the quantification of cell responses over long periods of time. This is performed with time-lapse video microscopy that gives a long sequence of frames. For th...
Human pluripotent stem cells (hPSCs) attract tremendous attention due to their unique properties. Manual extraction of trajectories of cell colonies in experimental image time series is labor intensive and subjective, thus the aim of the work was to...
The sensing/adapting/responding, multifunctionality, low energy, small size and weight, ease of forming, and low-cost attributes of SMART textiles and their multidisciplinary scope offer numerous end uses in medical, sports and fitness, military, fas...
Human Mesenchymal Stem Cells (hMSCs) and their derived products hold potential in tissue engineering and as therapeutics in a wide range of diseases. hMSCs possess the ability to aggregate into “spheroids”, which has been used as a precon...
In this work, we propose a hybrid control scheme to address the navigation problem for a team of disk-shaped robotic platforms operating within an obstacle-cluttered planar workspace. Given an initial and a desired configuration of the system, we dev...
In robot motion planning in a space with obstacles, the goal is to find a collision-free path for robots from the start to the target position. Numerous fundamentally different approaches, and their many variants, address this problem depending on th...
The Lévy walk is a pattern that is often seen in the movement of living organisms; it has both ballistic and random features and is a behavior that has been recognized in various animals and unicellular organisms, such as amoebae, in recent years. We...
Mammalian fertilization depends on sperm successfully navigating a spatially and chemically complex microenvironment in the female reproductive tract. This process is often conceptualized as a competitive race, but is better understood as a collectiv...
Organization of intracellular content is affected by multiple simultaneous processes, including diffusion in a viscoelastic and structured environment, intracellular mechanical work and vibrations. The combined effects of these processes on intracell...
In the present work, an analytical model of the vortex motion basic state of the dry atmosphere with nonzero air velocity divergence is constructed. It is shown that the air parcel moves along the open curve trajectory of spiral geometry. It is found...
In the present work an analytical model of the vortex motion elementary state of the dry atmosphere with nonzero air velocity divergence is constructed. It is shown that the air parcel moves along the open curve trajectory of spiral geometry. It is f...
Understanding the transport of small molecules such as oxygen in biological systems requires knowledge about how molecules dynamically interact with these molecules. This study investigates how red blood cells influence the diffusion of small molecul...
Under optimal conditions, just 3–6 ms of visual stimulation suffices for humans to see motion. Motion perception on this timescale implies that the visual system under these conditions reliably encodes, transmits, and processes neural signals w...
Cells are complex biological units that can sense physicochemical stimuli from their surroundings and respond positively to them through characterization of the cell behavior. Thus, understanding the motions of cells is important for investigating th...
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