Search Results (143)

Background: Basketball is characterized as a high-intensity, intermittent sport that places considerable demands on the cardiorespiratory, neuromuscular, and mechanical systems. These physiological requirements are modulated by contextual variables and the athlete’s stage of biological maturation, both of which significantly influence physical fitness outcomes. Consequently, it is imperative to employ age- and development-specific assessment protocols. Objectives: This study aimed to evaluate the differences in physical fitness across competitive categories and to explore the interrelationships among the various physical assessment tests. Twenty-four male players (U14 = 12; U16 = 12) participated in this research. Methods: Athletes were monitored using WIMUPRO inertial measurement units and completed the SBAFIT test battery to evaluate physical fitness parameters. Statistical analyses included both inferential and correlational approaches, with effect sizes calculated for all relevant variables. The independent variable was the competitive age category of the players. Results: The results indicated notable differences in physical performance between developmental groups, primarily attributed to biological maturation. Significant disparities were observed in measures of aerobic capacity, linear speed, agility, and centripetal force. Conclusions: The comparative nature of this study across developmental categories offers novel insights and practical implications for talent development and training optimization. Full article

High induction doses of propofol (PPF) may cause adverse effects. Co-induction protocols can reduce doses and enhance the beneficial profile of each drug. This study compared the induction quality, clinical, and echocardiographic effects of two rapid co-inductions in healthy, unpremedicated dogs. Baseline cardiorespiratory and echocardiographic variables were recorded. Dogs randomly received rapid intravenous PPF (2.2 mg/kg) with either dexmedetomidine (3 µg/kg) (PROPODEX; n = 12) or butorphanol (0.4 mg/kg) (PROPOBUT; n = 12). Induction quality, additional PPF dose, intubation time, cardiorespiratory parameters (2, 5, 10, 15, 20 min), and recovery quality were recorded. A second echocardiography was performed 5 min after induction. Induction quality was significantly higher in PROPODEX, with significantly lower additional PPF requirements and shorter intubation time. In PROPODEX, heart rate significantly decreased from baseline and was significantly lower than PROPOBUT, while arterial blood pressures significantly increased in PROPODEX and decreased in PROPOBUT from baseline. PROPOBUT significantly reduced left ventricular (LV) diastolic volumes and increased E/A ratio, while PROPODEX significantly increased LV systolic diameter and volumes, and significantly decreased fractional shortening. Recovery was significantly faster and better in PROPODEX. PROPOBUT preserved cardiac function but caused hypotension. PROPODEX provided superior induction and recovery quality, and cardiorespiratory stability, with only mild systolic function depression. Full article

Background: There is no information on how the dose of exercise training prior to myocardial infarction (MI) affects cardioprotection. Objective: This study aimed to evaluate the cardioprotective role of different volumes of exercise training prior to MI. Methods: Wistar female rats were allocated to one of the following groups: SHAM (not trained and undergoing simulated MI surgery), NT+MI (untrained and undergoing MI surgery), T60+MI (trained 60 min per session and undergoing MI surgery), T90+MI (trained 90 min per session and undergoing MI surgery), and T180+MI (trained 180 min per session and undergoing MI surgery). The training protocol was performed in a swimming pool for eight weeks. On the seventh day after MI, the animals underwent left ventricular (LV) structural and functional evaluation and were euthanized for molecular analyses. Results: Exercise training groups had greater VO₂peak and LV mass than did the SHAM group. The MI size did not differ statistically among the experimental groups. Compared with the SHAM group, all the MI groups presented a lower LV shortening fraction. LV systolic pressure was significantly lower in the T60+MI group than in the SHAM and T180+MI groups. The +dP/dt of the LV was significantly lower in the NT+MI, T60+MI, and T90+MI groups than in the SHAM group. We did not find significant changes in the inflammatory mediators and oxidative stress markers as well as proteins involved in calcium handling. Conclusions: Exercise training prior to MI enhanced cardiorespiratory fitness and induced LV hypertrophy, however, regardless of volume, was unable to counteract the detrimental effects of MI. Full article

(1) This systematic review evaluates the role of structured exercise within the Enhanced Recovery After Surgery (ERAS) protocol, a multidisciplinary approach designed to reduce surgical stress and enhance recovery. Prehabilitation, primarily through controlled physical activity, is a fundamental component of ERAS, preparing patients, both physically and mentally, for major surgery. (2) A systematic search following PRISMA guidelines was conducted using PubMed, ScienceDirect, Cochrane Library, Web of Science and Wiley databases to identify relevant studies published up to January 2025. Inclusion criteria encompassed randomized controlled trials, cohort studies, and meta-analyses reporting postoperative complications, length of hospital stay (LOS), and overall recovery. (3) A total of 64 studies met the inclusion criteria. The findings consistently demonstrate that structured exercise interventions—such as aerobic activities, resistance training, and flexibility routines—were associated with postoperative complications, shorten hospital stays, and enhance functional recovery. These interventions improve cardiorespiratory fitness, muscle strength, and psychological well-being. (4) Despite potential limitations in the systematic search, as heterogeneity of protocols, publication bias, language restrictions, the evidence supports the integration of structured exercise as a cornerstone of ERAS prehabilitation. Future research should focus on standardizing exercise protocols and exploring personalized strategies to optimize surgical outcomes across diverse patient populations. Full article

Cardiorespiratory fitness is a predictor of long-term health, traditionally assessed through structured exercise protocols that require maximal effort and controlled laboratory conditions. These protocols, while clinically validated, are often inaccessible, physically demanding, and unsuitable for unsupervised monitoring. This study proposes a non-invasive, unsupervised alternative—predicting the heart rate a person would reach after completing the step test, using wearable data collected during natural daily activities. Ground truth post-exercise heart rate was obtained through the Queens College Step Test, which is a submaximal protocol widely used in fitness settings. Separately, wearable sensors recorded heart rate (HR), blood oxygen saturation, and motion data during a protocol of lifestyle tasks spanning a range of intensities. Two machine learning models were developed—a Human Activity Recognition (HAR) model that classified daily activities from inertial data with 96.93% accuracy, and a regression model that estimated post step test HR using motion features, physiological trends, and demographic context. The regression model achieved an average root mean squared error (RMSE) of 5.13 beats per minute (bpm) and a mean absolute error (MAE) of 4.37 bpm. These findings demonstrate the potential of test-free methods to estimate standardized test outcomes from daily activity data, offering an accessible pathway to infer cardiorespiratory fitness. Full article

Laboratory-based assessment of cardiorespiratory function is a widely applied method in sports science. Most performance evaluations focus on oxygen uptake parameters. Despite the well-established concept of oxygen deficit introduced by Hill in the 1920s, relatively few studies have examined its behavior during submaximal exercise, with limited exploration of deficit dynamics. The present study aimed to analyze the behavior of oxygen deficit in young female handball players (N = 42, age: 15.4 ± 1.3 years) during graded exercise. Oxygen deficit was estimated using the American College of Sports Medicine (ACSM) algorithm, restricted to subanaerobic threshold segments of a quasi-ramp exercise protocol. Cardiorespiratory parameters were measured with the spiroergometry test on treadmills, and body composition was assessed via Dual Energy X-ray Absorptiometry (DEXA). Cluster and principal component analyzes revealed two distinct athlete profiles with statistically significant differences in both morphological and physiological traits. Cluster 2 showed significantly higher relative VO₂ peak (51.43 ± 3.70 vs. 45.70 ± 2.87 mL·kg⁻¹·min⁻¹; p < 0.001; Cohen’s d = 1.76), yet also exhibited a greater oxygen deficit per kilogram (39.03 ± 16.71 vs. 32.56 ± 14.33 mL·kg⁻¹; p = 0.018; d = 0.80). Cluster 1 had higher absolute body mass (69.67 ± 8.13 vs. 59.66 ± 6.81 kg; p < 0.001), skeletal muscle mass (p < 0.001), and fat mass (p < 0.001), indicating that body composition strongly influenced oxygen deficit values. The observed differences in oxygen deficit profiles suggest a strong influence of genetic predispositions, particularly in cardiovascular and muscular oxygen utilization capacity. Age also emerged as a critical factor in determining the potential for adaptation. Oxygen deficit during submaximal exercise appears to be a multifactorial phenomenon shaped by structural and physiological traits. While certain influencing factors can be modified through training, others especially those of genetic origin pose inherent limitations. Early development of cardiorespiratory capacity may offer the most effective strategy for long-term optimization. Full article

Background: Chronic stress in childhood and adolescence leads to excessive cortisol secretion, adipokines production and obesity with all the negative mental and physical effects on the health of individuals and adulthood. Objectives: The aim of the present non-randomized controlled trial was to investigate the effect of a stress management protocol with diaphragmatic breathing (DB) and physiotherapy exercise on stress, body composition, cardiorespiratory and metabolic markers of children and adolescents with morbid obesity. Methods: The study included 31 children and adolescents (5–18 years old) with morbid obesity (22 in the intervention arm and 9 controls). All participants completed anxiety questionnaires and a self-perception scale. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), blood pressure (BP) and SpO₂ were measured. Fasting glucose, uric acid, triglycerides, HbA1c, (AST/SGOT), (ALT/SGPT), HDL, LDL, insulin, ACTH, cortisol, HOMA-IR, 17-OH, S-DHEA, SHBG were assessed, and anthropometric measurements were also performed. Results: In the intervention group, 4 months after the treatment, an improvement was noted in the BMI, BMI z-score, waist-to-height ratio, FEV1, SpO₂, pulse and systolic BP. HDL increased, ALT/SGPT and insulin resistance improved. Positive changes were observed in temporary and permanent stress and self-esteem of children in the intervention group, including anxiety, self-perception, physical appearance, etc. Conclusions: A combined exercise and DB protocol has a positive effect on stress, by improving body composition, reducing insulin resistance, and ameliorating physical and mental health and quality of life of pediatric patients with morbid obesity. Full article

Colorectal cancer (CRC) remains a leading cause of cancer morbidity and mortality worldwide, especially in older adults where frailty complicates treatment outcomes. Multimodal prehabilitation—comprising nutritional support, physical exercise, and psychological interventions—has emerged as a promising strategy to enhance patients’ resilience before CRC surgery. Clinical studies demonstrate that prehabilitation significantly reduces postoperative complications, shortens hospital stays, and improves functional recovery. Nutritional interventions focus on counteracting malnutrition and sarcopenia through tailored dietary counseling, protein supplementation, and immunonutrients like arginine and glutamine. Physical exercise enhances cardiorespiratory fitness and muscle strength while modulating immune and metabolic pathways critical for surgical recovery. Psychological support reduces anxiety and depression, promoting mental resilience that correlates with better postoperative outcomes. Despite clear clinical benefits, the molecular mechanisms underlying prehabilitation’s effects—such as inflammation modulation, immune activation, and metabolic rewiring—remain poorly understood. This review addresses this knowledge gap by exploring potential biological pathways influenced by prehabilitation, aiming to guide more targeted, personalized approaches in CRC patient management. Advancing molecular insights may optimize prehabilitation protocols and improve survival and quality of life for CRC patients undergoing surgery. Full article

We examined the physiological demands of trained rowers across four exercise intensity domains (considering the effects of weight category and sex). Twenty-four trained rowers (12 lightweight and 12 heavyweight) performed 7 × 3 min incremental bouts on a Concept2 rowing ergometer (30 W power increases and 60 s rest intervals). Performance, cardiorespiratory and metabolic responses were continuously assessed throughout the experimental protocol to characterize internal load across progressive exercise intensities. Statistical analyses included a repeated measures ANOVA test and independent t-tests (p ≤ 0.05). Heavyweight rowers exhibited greater absolute anaerobic energy production in the severe domain (41.25 ± 10.39 vs. 32.54 ± 5.92 kJ) (p = 0.02), higher peak metabolic power (up to 1.57 ± 0.30 vs. 1.48 ± 0.30 kW) (p = 0.001) and greater total energy expenditure (up to 277.52 ± 51.23 vs. 266.69 ± 51.59 kJ) (p = 0.001) than lightweight rowers, whereas the latter showed comparable relative cardiorespiratory responses to heavyweights. With respect to sex differences, males demonstrated higher oxygen uptake (from ~43–59 vs. ~34–48 mL·kg⁻¹·min⁻¹) (p = 0.001), ventilation (from ~78–146 vs. ~49–99 L·min⁻¹) (p = 0.001), metabolic power (from ~1.1–1.7 vs. ~0.7–1.0 kW) (p = 0.001) and energy expenditure (from ~193–305 vs. ~119–209 kJ) (p = 0.001) across all intensity domains. However, blood lactate levels and anaerobic energy contributions were similar between sexes. These findings demonstrated that domain-based physiological profiling effectively differentiates internal responses among rowers by weight category and sex. Heavyweights showed greater absolute energy output, while lightweights demonstrated higher metabolic efficiency. Males had elevated cardiorespiratory and metabolic values, but relative bioenergetic responses were similar across groups. These findings support individualized training based on physiological profiles. Full article

Wheelchair tennis (WT) is a Paralympic sport designed for athletes with physical impairments. Assessing physical fitness characteristics using appropriate field-based tests and standardized protocols is essential for individualized training, injury prevention, and performance monitoring. However, there is currently limited information on which field-based tests are most suitable and how they should be applied in WT athletes, resulting in inconsistency across studies and practical use. Establishing a standard operating procedure (SOP) enables replicable, cost-effective testing routines that improve data consistency and comparability. We conducted a scoping review to synthesize the existing evidence on field-based physical fitness assessment in WT athletes and to propose a structured SOP for these tests. A comprehensive search was conducted in three electronic databases—NLM PubMed, Web of Science, and Scopus—using predefined keywords and Boolean operators. The inclusion criteria were limited to peer-reviewed, English-language original articles focusing exclusively on field tests in WT athletes. Studies with other populations, reviews, and abstracts were excluded. Eleven studies met the eligibility criteria. This scoping review identified various field tests assessing key fitness components, including cardiorespiratory endurance, muscle strength, agility, and body composition. The most frequently employed tests were the 20 m sprint test, isometric handgrip test, spider test, Illinois Agility Test, and skinfold thickness. These findings highlight the lack of standardized fitness assessments in WT. The proposed SOP offers a practical step toward consistent, replicable, and relevant evaluation in these athletes. Full article

Background/Objectives: High-intensity interval training (HIIT) can optimize recovery by complementing the low cardiovascular fitness intensities typically achieved in stroke rehabilitation programs. Skating exercise is an HIIT workout developed based on ice skating movements, and we investigated the effects of this exercise on the cardiorespiratory fitness of elderly patients with minor stroke. Methods: Participants aged 65 or older with a National Institutes of Health Stroke Scale score of 3 or lower were recruited. This study was designed as a randomized controlled trial, in which the intervention group engaged in skating exercises following HIIT, while the control group underwent moderate-intensity continuous training (MICT). Both groups of participants performed either HIIT or MICT for 20 min per day, four times a week, over three months. Results: A total of 34 elderly patients with minor stroke were recruited, with an average age of 70.7 years. For three months, no fall-down injuries or adverse cardiovascular or cerebrovascular events were reported among patients undergoing HIIT or MICT. Both the intervention and control groups showed significant increases in the measures of aerobic capacity after the intervention. However, the patients in the intervention group exhibited significantly greater improvements in peak oxygen uptake, ventilatory threshold, and peak MET (p = 0.005, p = 0.002, and p = 0.024, respectively). Additionally, the Berg Balance Scale (BBS) scores and the skeletal muscle mass index showed significantly greater enhancements in the intervention group compared to the control group (p = 0.032 and p = 0.032). Conclusions: In conclusion, skating exercise could be a safe and effective HIIT protocol for elderly people who have experienced a minor stroke. Full article

This study investigated physiological differences in cardiorespiratory and metabolic performance parameters between professional football players from top- (TR) and mid-ranked teams (MR) in the Serbian Super League. A total of 55 male outfield players (TR: n = 29; MR: n = 26) were assessed in March 2022 using a maximal multistage treadmill protocol and lactate analysis. The key cardiorespiratory variables included maximum oxygen uptake (VO₂max), heart rate at the anaerobic threshold (HR AT), and recovery heart rate metrics, while the metabolic variables focused on lactate concentrations and efficiency indices. The results indicate that the TR players achieved significantly lower HR AT values (162 ± 10.26 vs. 168.77 ± 7.28 bpm; p = 0.017) and demonstrated superior second-minute recovery (%Re 2′: 66.62 ± 14.08% vs. 34.53 ± 9.13%, p < 0.001). In contrast, the MR players exhibited higher VO₂max (62.65 ± 4.48 vs. 60.06 ± 3.29 mL/kg/min; p = 0.017) and greater cardiorespiratory efficiency scores. The lactate parameters were comparable between the groups, except for the metabolic efficiency index (Index ME), which were favorable among the TR players (p = 0.011). These findings highlight that while MR players possess higher aerobic capacity, TR players demonstrate superior physiological recovery and metabolic control, reflecting adaptations to different tactical demands and match intensities. The results offer practical implications for individualized training design and performance monitoring in elite football settings. Full article

Background and Objectives: Individuals with chronic obstructive pulmonary disease (COPD) often exhibit some degree of intolerance to physical exercise and several limitations in daily activities. Therefore, the objective of this study was to conduct a scoping review on the characteristics—frequency, intensity, time, and type (FITT)—and the effects of exercise programs on quality of life and functional capacity in individuals with COPD. Materials and Methods: The present review included 21 studies that were scoping-reviewed to describe their main findings and training characteristics. Results: The participants across studies ranged in age from ~39 to 76 years with mild to very severe COPD stages. The results showed that, among all studies, eleven used cardiorespiratory training (e.g., walking or cycling), five used strength training (e.g., exercises with elastic bands or traditional resistance training), and five implemented combined training (i.e., cardiorespiratory and strength exercises). Conclusions: Overall, all training protocols improved aerobic capacity (cardiorespiratory training), strength (resistance training), and both capacities together (combined training). In conclusion, this review provided complementary insights to existing exercise prescription guidelines, particularly concerning cardiorespiratory, strength, and combined training in individuals with COPD. However, the methodologies of the training protocols varied widely, and detailed descriptions of FITT components were often incomplete or lacking clarity, especially regarding the specific exercises used. Future research should include more comprehensive spirometry variables such as forced expiratory volume 1 or forced vital capacity, as these are critical for determining COPD stages. Thus, there is a clear need for more high-quality research with robust methodological design in the context of exercise interventions for individuals with COPD. Full article

Background: Survivors of hematopoietic stem cell transplantation (HSCT) during childhood face significant late effects. This study aimed to map the dietary micronutrient intake of long-term survivors of pediatric HSCT and explore its associations with transplant outcomes, body composition, and physical capacity. Methods: We included 85 long-term survivors of HSCT (median age 30 years) The median time since HSCT was 19.9 years, reflecting a long-term survivor population. Dietary intake was assessed using a 3-day food record. Body composition was measured by DXA, and physical capacity was evaluated through cardiorespiratory fitness and physical performance tests. Results: We observed an inadequate intake of several vitamins and minerals including vitamins A, C, D, E, selenium, and potassium, with a median intake below recommendations. While dietary intake of vitamin D was reduced in patients with chronic graft versus host disease (cGvHD), the occurrence of cGvHD was not associated with overall micronutrient intake. Twelve percent of the participants had reduced skeletal muscle mass and 16% displayed a low bone mass density during DXA scans. These conditions were not related to the micronutrient intake. Likewise, reduced cardiorespiratory fitness and physical performance were unrelated to micronutrient intake. Total energy intake was found to significantly influence micronutrient intake (p = 0.001), explaining 66% of the variation. Conclusions: Long-term survivors of pediatric HSCT demonstrated inadequate intake of multiple micronutrients. These findings suggest that inclusion of comprehensive micronutrient assessment and nutritional guidance should be considered for inclusion in follow-up care protocols. Full article

The global aging trend increases chronic diseases and lowers quality of life. Exercise is vital for physiological, cognitive, and mental health, countering age-related decline. Outdoor multidomain interventions enhance adherence, motivation, and resilience, supporting independence and well-being. Objectives: This paper aimed to apply an outdoor exercise protocol for middle-aged and older people and to study its preliminary effects on cognitive state, body composition, cardiovascular health, physical fitness, physiological function, physical activity, frailty, incidence of sarcopenia, and satisfaction with life. Methods: This protocol describes an eighteen-week, two-pronged, parallel, single-blind randomized controlled trial. This paper complies with the Consort and SPIRIT guidelines. A cohort comprising a minimum of fifty-two older adults from the University for Seniors program will be equally allocated to a multidomain training group (TG) and a passive control group (CG). Intervention: The TG will follow a multidomain outdoor intervention twice a week for a complete duration of 18 weeks, with recommendations for additional autonomous cardiorespiratory training. The supervised sessions will be divided into a 10-min warm-up session focusing on activation and joint mobility, followed by 40 min of resistance training, cardiorespiratory training, and balance and coordination; and it concludes with a 10-min cool-down featuring flexibility, relaxation, and playful emotional intelligence tasks. Cognitive training will be integrated across different parts of the session. Conclusions: This preliminary study aims to explore the feasibility and potential effectiveness of outdoor multidomain training in improving the health of older adults. Importantly, by including late middle-aged adults from the age of 55, this study also aims to explore the potential of preventive strategies initiated before reaching old age. This reflects a broader conceptualization of healthy aging as a lifelong process, where early interventions may help mitigate decline and extend independence into later life. The partnership between health professionals and physical activity fosters independence for older adults, addressing the increasing burden on health services. Full article