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Search Results (135)

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19 pages, 6981 KB  
Article
Design and Optimization of a Dust Suppression System in a Comprehensive Mining Face
by Yingjie Liu, Jiayi Li, Yongbo Cai, Zuo Sun and Chao Xu
Processes 2026, 14(9), 1405; https://doi.org/10.3390/pr14091405 - 28 Apr 2026
Abstract
Fully mechanized coal mining is a key method of coal extraction. As mining intensity increases, dust pollution in fully mechanized mining faces has become increasingly severe, significantly hindering the coal industry‘s alignment with the “Healthy China” strategy. To address the prominent dust pollution [...] Read more.
Fully mechanized coal mining is a key method of coal extraction. As mining intensity increases, dust pollution in fully mechanized mining faces has become increasingly severe, significantly hindering the coal industry‘s alignment with the “Healthy China” strategy. To address the prominent dust pollution and the inefficiency of current spray dust suppression methods, this study proposes a combined spray dust suppression system. Using the Taigemiao mining area—where the coal dust exhibits hydrophilic characteristics—as a case study, we investigate the system’s spray flow field characteristics via numerical simulation. The results indicate that activating the shearer‘s external nozzles increases the airflow velocity near the shearer to 4 m/s, with the droplet concentration at the breathing zone height peaking at 28,786 mg/m3. Furthermore, activating the inter-support spray-induced dust removal device boosts the airflow velocity to 15.8 m/s, generating negative pressure at the dust suction inlet and forming a high-concentration droplet zone near the coal wall. During the operation of the combined system, the droplet distribution is characterized by “three high-concentration areas” and “post-nozzle attenuation.” The optimal droplet proportion reaches 93.81%, maintaining an appropriate velocity within the efficient dust capture range. Overall, the dust capture efficiency of the combined system is significantly superior to that of a single spray system. Full article
(This article belongs to the Special Issue Research Progress in Dust Control Technology)
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13 pages, 415 KB  
Article
Clinical Predictors of Dosimetric Precedence for Deep Inspiratory Breath Hold Radiation Therapy for Breast Cancer
by Alzahra’a Al Matairi, Abdulla Alzibdeh, Issa Mohamad, Ramiz Abu-Hijlih, Wafa Asha, Fadwa Abdel Rahman, Haitham Kanaan, Soha Ahmad, Hikmat Abdel-Razeq and Fawzi Abuhijla
Diagnostics 2026, 16(8), 1236; https://doi.org/10.3390/diagnostics16081236 - 21 Apr 2026
Viewed by 228
Abstract
Background/Objectives: Radiation therapy for left-sided breast cancer exposes the heart and lungs to incidental radiation, increasing long-term risk of cardiopulmonary morbidity. This study evaluated the dosimetric impact of DIBH compared with free breathing (FB) and explored patient- and treatment-related predictors of benefit. [...] Read more.
Background/Objectives: Radiation therapy for left-sided breast cancer exposes the heart and lungs to incidental radiation, increasing long-term risk of cardiopulmonary morbidity. This study evaluated the dosimetric impact of DIBH compared with free breathing (FB) and explored patient- and treatment-related predictors of benefit. Methods: We retrospectively analyzed 90 patients with left-sided breast cancer or chest wall irradiation planned under both FB and DIBH. Dosimetric parameters included mean heart dose (MHD), mean lung dose (MLD), heart V5, and lung V20. Univariable analyses assessed associations between dose reductions (Δ%) and clinical factors (age, BMI, fractionation, boost, nodal fields, and smoking). Multivariable regression identified independent predictors. Results: DIBH significantly reduced mean doses to the heart (FB 4.25 ± 1.47 Gy vs. DIBH 2.64 ± 1.28 Gy; Δ −1.60 Gy, p < 0.001, and Cohen’s d = 2.46) and lung (FB 14.00 ± 3.45 Gy vs. DIBH 11.64 ± 3.32 Gy; Δ −2.36 Gy, p < 0.001, and Cohen’s d = 2.73). Similarly, heart V5 (median Δ −10.5%, p < 0.001) and lung V20 (median Δ −5.5%, p < 0.001) were significantly improved. Higher BMI was independently associated with smaller relative reductions in MHD (−1.4% per unit, p < 0.001) and MLD (−0.31% per unit, p = 0.019). Hypofractionation was linked to greater MHD and MLD reductions (+8.9%, p = 0.007), (3.7%, p = 0.035), respectively. Supraclavicular field irradiation increased lung exposure, while internal mammary chain fields elevated both lung and heart doses. Age showed no significant influence. Conclusions: DIBH provides robust and consistent reductions in cardiac and pulmonary radiation doses during left-sided breast irradiation. The degree of sparing is modulated by BMI, fractionation, and nodal field inclusion. Full article
(This article belongs to the Special Issue Innovations in Imaging for Radiation Oncology)
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22 pages, 2330 KB  
Review
Beyond One-Size-Fits-All: Precision Mechanical Ventilation in ARDS
by Saif Azzam, Karis Khattab, Sarah Al Sharie, Lou’i Al-Husinat, Pedro L. Silva, Denise Battaglini, Marcus J Schultz and Patricia R M Rocco
J. Clin. Med. 2026, 15(5), 2058; https://doi.org/10.3390/jcm15052058 - 8 Mar 2026
Viewed by 1426
Abstract
Acute respiratory distress syndrome (ARDS) has traditionally been managed with population-based, protocolized mechanical ventilation strategies designed to limit ventilator-induced lung injury. While these approaches have improved outcomes, they fail to account for the pronounced biological, mechanical, radiological, and temporal heterogeneity that characterizes ARDS. [...] Read more.
Acute respiratory distress syndrome (ARDS) has traditionally been managed with population-based, protocolized mechanical ventilation strategies designed to limit ventilator-induced lung injury. While these approaches have improved outcomes, they fail to account for the pronounced biological, mechanical, radiological, and temporal heterogeneity that characterizes ARDS. Accumulating evidence shows that patients differ markedly in functional lung size, recruitability, chest wall mechanics, inflammatory burden, and tolerance to ventilatory stress, making uniform ventilatory targets physiologically imprecise and, at times, harmful. This narrative review examines the evolution from conventional lung-protective ventilation toward a precision-based paradigm that aligns ventilatory support with individual patient physiology. We conceptualize ARDS not as a static syndrome but as a dynamic spectrum, viewing the injured lung as a heterogeneous mechanical system susceptible to regionally amplified stress and strain. Within this framework, we discuss key principles underlying precision ventilation, including functional lung size (the “baby lung”), driving pressure, mechanical power, patient–ventilator interaction, spontaneous breathing-associated injury, and the time-dependent evolution of lung mechanics. We synthesize current evidence supporting mechanical, biological, and radiological subphenotyping as complementary strategies to individualize ventilatory management, while critically appraising their current limitations. This review also evaluates bedside tools that may operationalize precision ventilation in clinical practice, including esophageal pressure monitoring, lung ultrasound, and electrical impedance tomography, and examines the role of artificial intelligence as a clinician-directed decision-support aid rather than a prescriptive substitute for physiological reasoning. Implications for clinical trial design, ethical considerations, and future directions toward predictive and adaptive ventilation strategies are also addressed. Precision mechanical ventilation represents a shift from rigid thresholds toward proportional, physiology-guided intervention across the disease trajectory. By integrating evolving lung mechanics, ventilatory load, and patient effort over time, this approach provides a coherent framework for safer and more effective mechanical ventilation in ARDS while preserving the core principles of lung protection. Full article
(This article belongs to the Special Issue Personalized Treatments for Patients with Acute Lung Injury)
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19 pages, 4427 KB  
Review
Chest Discomfort: Could Coronary Pathology Extend Beyond Atherosclerosis?
by Ana Mladenovic Markovic, Ana Tomic, Miodrag Nisevic, Olga Nedeljkovic Arsenovic, Jelica Vukmirovic, Jelena Kostic, Aleksandar Filipovic, Ljiljana Bogdanovic and Vojislav Giga
J. Clin. Med. 2026, 15(3), 1185; https://doi.org/10.3390/jcm15031185 - 3 Feb 2026
Viewed by 641
Abstract
Background/Objectives: Non-atherosclerotic pathological findings on coronary arteries involve various disorders that might lead to myocardial ischemia, independent of plaque complications and consequent lumen narrowing and obstruction. These patients often present with non-specific symptoms such as shortness of breath, rapid fatigue, and exertional [...] Read more.
Background/Objectives: Non-atherosclerotic pathological findings on coronary arteries involve various disorders that might lead to myocardial ischemia, independent of plaque complications and consequent lumen narrowing and obstruction. These patients often present with non-specific symptoms such as shortness of breath, rapid fatigue, and exertional chest tightness. When the underlying causes are non-atherosclerotic, these findings are frequently overlooked in radiology reports as a possible differential diagnosis. Therefore, the objective of this paper is to present the role of multidetector computed tomography (MD CT) coronary angiography in the diagnostic work-up of patients with rare but clinically valuable non-atherosclerotic pathological conditions of coronary arteries. Methods: We performed a literature search on Medline (via PubMed) for works presenting data on rare, non-occlusive, pathological findings on coronary arteries. Results: The review of the collected literature was performed in a narrative manner, intended to summarize mainly findings of imaging characteristics of non-occlusive pathologies: myocardial bridge, coronary aneurysm, ectasia, fistula, stenosis, and dissection. MD CT images of selected cases that were examined at our department, showing non-occlusive pathological changes in the coronary arteries, are displayed in planar and/or volume-rendered formats. Conclusions: Non-atherosclerotic abnormalities of the coronary vessel wall should be considered in the differential diagnosis of coronary causes of chest pain, dyspnea, and arrhythmias, as they may lead to both acute and chronic myocardial ischemia. Based on the presented literature and specific cases from our clinical practice, MD CT is shown to be an important tool for the rapid, non-invasive evaluation of non-atherosclerotic pathologies. Full article
(This article belongs to the Special Issue Clinical Updates in Cardiovascular Computed Tomography (CT))
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21 pages, 4760 KB  
Article
Experimentally Informed Numerical Simulations of Spray Deposition and Runoff Doses in a 10-Day-Old Nose Model
by Jack Yongfeng Zhang, Mary Ziping Luo, Ray Lameng Lei, Sung-An Lin, Xiuhua Si and Jinxiang Xi
Pharmaceuticals 2026, 19(2), 217; https://doi.org/10.3390/ph19020217 - 27 Jan 2026
Viewed by 594
Abstract
Background: Intranasal drug delivery is a preferred route for emergency administration of naloxone in opioid overdose due to its rapid onset of action and ease of use. However, limited knowledge exists on the delivery efficiency and safety of nasal sprays in neonates, particularly [...] Read more.
Background: Intranasal drug delivery is a preferred route for emergency administration of naloxone in opioid overdose due to its rapid onset of action and ease of use. However, limited knowledge exists on the delivery efficiency and safety of nasal sprays in neonates, particularly in life-threatening situations such as coma states where breathing is compromised. This study presents a physiology-based simulation of spray deposition and runoff loss in a 10-day-old infant nose model. Methods: Spray characteristics, including droplet size distribution, exiting velocity, and plume angle, were measured and implemented in ANSYS Fluent droplet tracking model. Naloxone film thickness was measured on ex vivo porcine nasal mucosa at varying angles and used in the Eulerian Wall-Film model. Simulations were conducted in a 10-day-old nose geometry across multiple doses (0.25, 0.50, 1.0, and 2.0 mL) in supine and 45° inclined postures to quantify regional deposition, liquid film translocation, and pharyngeal runoff. Results: While a 0.25 mL spray was fully retained in the nasal passages, higher doses exceeded the mucosal holding capacity and caused significant runoff. Runoff into the pharynx was 18.5% and 10.1% for the spray volume of 0.50 mL in the 45° back tilt and supine positions, respectively. The 1.0 mL spray caused 55.1% and 53.5% runoff in the 45° back tilt and supine positions, while the 2.0 mL spray caused 77.5% and 76.8% runoff in the 45° back tilt and supine positions, respectively. Conclusions: These findings highlight the critical influence of spray volume on drug delivery outcomes in neonates and provide quantitative guidance for optimizing intranasal naloxone administration in emergency pediatric care. Full article
(This article belongs to the Section Pharmaceutical Technology)
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30 pages, 6038 KB  
Article
Deposition of Occupational Aerosol Particles in a Three-Dimensional Adult Nasal Cavity Model: An Experimental Study
by Anna Rapiejko, Tomasz R. Sosnowski, Krzysztof Sosnowski and Dariusz Jurkiewicz
Bioengineering 2026, 13(2), 132; https://doi.org/10.3390/bioengineering13020132 - 23 Jan 2026
Cited by 1 | Viewed by 819
Abstract
Background: Occupational exposure to aerosol particles can pose a substantial health risk. The study aimed to characterise the deposition of occupationally relevant aerosols in a 3D anatomical adult nasal cavity model under steady and unsteady flows. Materials: The deposition of aerosolised [...] Read more.
Background: Occupational exposure to aerosol particles can pose a substantial health risk. The study aimed to characterise the deposition of occupationally relevant aerosols in a 3D anatomical adult nasal cavity model under steady and unsteady flows. Materials: The deposition of aerosolised wheat flour, pine wood sanding dust, carbon black, and Arizona Test Dust A3 was quantified under steady flows (5, 7.5, and 20 L/min per nostril) and an unsteady breathing pattern generated by the commercial breathing simulator. Image analysis with custom software quantified the area covered by deposited particles. The Downstream Penetration Index (DPI) was determined from the outlet mass. Results: The highest segmental deposition occurred in the anterior segment of the lateral wall (WA) and septum (SA), with moderate values in the middle lateral wall (WM) and the lowest in the posterior lateral wall (WP, nasopharynx) and septum (SP). Arizona Test Dust A3 and carbon black demonstrated higher middle-posterior deposition and DPI, consistent with finer particle size distributions (PSD) and greater sub-10 µm fractions. In contrast, wheat flour and pine wood dust, with larger median particle sizes and lower sub-10 µm fractions, showed stronger anterior filtration and lower DPI. Increased flow enhanced anterior filtration of coarse particles and shifted deposition forward, aligning with increased inertial impaction, but elevated DPI for fine particles. Under unsteady flow, deposition was intermediate between 7.5 and 20 L/min. Conclusions: This study shows that PSD, morphology, and flow conditions influence nasal deposition. Coarse aerosols were filtered in the anterior nose, while fine-rich aerosols showed relatively greater middle-posterior deposition and higher DPI. These findings are essential for assessing occupational exposure and developing interventions and prevention strategies. Full article
(This article belongs to the Section Biomedical Engineering and Biomaterials)
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50 pages, 16753 KB  
Article
Spectral Energy of High-Speed Over-Expanded Nozzle Flows at Different Pressure Ratios
by Manish Tripathi, Sławomir Dykas, Mirosław Majkut, Krystian Smołka, Kamil Skoczylas and Andrzej Boguslawski
Energies 2025, 18(21), 5813; https://doi.org/10.3390/en18215813 - 4 Nov 2025
Viewed by 919
Abstract
This paper addresses the long-standing question of understanding the origin and evolution of low-frequency unsteadiness interactions associated with shock waves impinging on a turbulent boundary layer in transonic flow (Mach: 1.1 to 1.3). To that end, high-speed experiments in a blowdown open-channel [...] Read more.
This paper addresses the long-standing question of understanding the origin and evolution of low-frequency unsteadiness interactions associated with shock waves impinging on a turbulent boundary layer in transonic flow (Mach: 1.1 to 1.3). To that end, high-speed experiments in a blowdown open-channel wind tunnel have been performed across a convergent–divergent nozzle for different expansion ratios (PR = 1.44, 1.6, and 1.81). Quantitative evaluation of the underlying spectral energy content has been obtained by processing time-resolved pressure transducer data and Schlieren images using the following spectral analysis methods: Fast Fourier Transform (FFT), Continuous Wavelet Transform (CWT), as well as coherence and time-lag evaluations. The images demonstrated the presence of increased normal shock-wave impact for PR = 1.44, whereas the latter were linked with increased oblique λ-foot impact. Hence, significant disparities associated with the overall stability, location, and amplitude of the shock waves, as well as quantitative assertions related to spectral energy segregation, have been inferred. A subsequent detailed spectral analysis revealed the presence of multiple discrete frequency peaks (magnitude and frequency of the peaks increasing with PR), with the lower peaks linked with large-scale shock-wave interactions and higher peaks associated with shear-layer instabilities and turbulence. Wavelet transform using the Morlet function illustrates the presence of varying intermittency, modulation in the temporal and frequency scales for different spectral events, and a pseudo-periodic spectral energy pulsation alternating between two frequency-specific events. Spectral analysis of the pixel densities related to different regions, called spatial FFT, highlights the increased influence of the feedback mechanism and coupled turbulence interactions for higher PR. Collation of the subsequent coherence analysis with the previous results underscores that lower PR is linked with shock-separation dynamics being tightly coupled, whereas at higher PR values, global instabilities, vortex shedding, and high-frequency shear-layer effects govern the overall interactions, redistributing the spectral energy across a wider spectral range. Complementing these experiments, time-resolved numerical simulations based on a transient 3D RANS framework were performed. The simulations successfully reproduced the main features of the shock motion, including the downstream migration of the mean position, the reduction in oscillation amplitude with increasing PR, and the division of the spectra into distinct frequency regions. This confirms that the adopted 3D RANS approach provides a suitable predictive framework for capturing the essential unsteady dynamics of shock–boundary layer interactions across both temporal and spatial scales. This novel combination of synchronized Schlieren imaging with pressure transducer data, followed by application of advanced spectral analysis techniques, FFT, CWT, spatial FFT, coherence analysis, and numerical evaluations, linked image-derived propagation and coherence results directly to wall pressure dynamics, providing critical insights into how PR variation governs the spectral energy content and shock-wave oscillation behavior for nozzles. Thus, for low PR flows dominated by normal shock structure, global instability of the separation zone governs the overall oscillations, whereas higher PR, linked with dominant λ-foot structure, demonstrates increased feedback from the shear-layer oscillations, separation region breathing, as well as global instabilities. It is envisaged that epistemic understanding related to the spectral dynamics of low-frequency oscillations at different PR values derived from this study could be useful for future nozzle design modifications aimed at achieving optimal nozzle performance. The study could further assist the implementation of appropriate flow control strategies to alleviate these instabilities and improve thrust performance. Full article
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12 pages, 937 KB  
Article
Breath Stacking: Acute Effects on Cough Peak Flow and Chest Wall Volumes of Healthy Subjects
by Ana Cristina de Medeiros Garcia Maciel, Vanessa Regiane Resqueti, Jéssica Danielle Medeiros da Fonseca, Illia Nadinne Dantas Florentino Lima, Matías Otto-Yáñez, Rêncio Bento Florêncio, Andrea Aliverti, Guilherme Augusto de Freitas Fregonezi and Arméle de Fátima Dornelas de Andrade
J. Funct. Morphol. Kinesiol. 2025, 10(4), 421; https://doi.org/10.3390/jfmk10040421 - 29 Oct 2025
Viewed by 1497
Abstract
Objectives: The aim of this study was to investigate the acute physiological effects of the BS on CPF and chest wall volumes in healthy individuals, comparing two body positions: supine and 45° trunk inclination. Methods: Observational, analytical, and cross-sectional study conducted with 14 [...] Read more.
Objectives: The aim of this study was to investigate the acute physiological effects of the BS on CPF and chest wall volumes in healthy individuals, comparing two body positions: supine and 45° trunk inclination. Methods: Observational, analytical, and cross-sectional study conducted with 14 healthy individuals (7 males) who underwent the BS in two different body positions. CPF, tidal chest wall volumes and the contribution of thoracoabdominal compartments were assessed using Optoelectronic Plethysmography. Statistical analyses included two-way ANOVA and Bonferroni post hoc tests, with a significance level of 5%. Results: A significant increase in CPF was observed after the BS in the inclined position (p < 0.05), with no relevant changes in the supine position. Tidal chest wall volumes also increased in both positions, with a more pronounced effect in the 45° inclination (p < 0.05). The volume increase was predominantly thoracic, with a ventilatory redistribution favouring the pulmonary rib cage compartment, especially in the inclined posture. Conclusions: The BS produced immediate beneficial physiological effects in healthy individuals, with greater efficacy in the inclined position, enhancing expiratory flow and thoracic ventilation. These findings support the clinical applicability of BS as a physiotherapeutic strategy even in populations without respiratory dysfunction. Full article
(This article belongs to the Section Kinesiology and Biomechanics)
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11 pages, 702 KB  
Article
Effect of Inspiratory Muscle Training on Diaphragm and Abdominal Wall Muscle Thickness with Fatty Liver Density in Elderly Women: A Randomized Controlled Trial
by Eda Gökçelik, Coşkun Yılmaz, Cemallettin Budak, Hakan Hüseyin Soylu, Serdar Bayrakdaroğlu, Halil İbrahim Ceylan, Raul Ioan Muntean, Hamza Küçük and Levent Ceylan
Medicina 2025, 61(10), 1784; https://doi.org/10.3390/medicina61101784 - 2 Oct 2025
Cited by 3 | Viewed by 3327
Abstract
Background and Objectives: Post-menopausal estrogen decline is considered a contributing factor to sarcopenia, and inspiratory muscle training (IMT) may provide benefits in this demographic. This study examined the impact of a four-week IMT program on diaphragm thickness, abdominal wall muscle thickness (AWMT; transversus [...] Read more.
Background and Objectives: Post-menopausal estrogen decline is considered a contributing factor to sarcopenia, and inspiratory muscle training (IMT) may provide benefits in this demographic. This study examined the impact of a four-week IMT program on diaphragm thickness, abdominal wall muscle thickness (AWMT; transversus abdominis, internal oblique, and external oblique), and liver fat percentage in healthy elderly women. Materials and Methods: Twenty-six women aged 60–80 years were randomly assigned to an IMT group (n = 13) or a control group (n = 13). The IMT group used the PowerBreathe® Classic device at 40% of maximal inspiratory pressure (MIP), with weekly increments of 10%. Training was performed twice daily, five days per week, with 30 breathing cycles per session (60 per day). The control group maintained their usual routines. AWMT, diaphragm thickness (DT), and fatty liver density (FLD) were measured by a radiologist before and after the intervention. Results: After four weeks, the IMT group showed significant improvements in all parameters compared to controls. Mid-diaphragm thickness (MDT) increased by 11.44% (effect size (ES) = 0.358, p < 0.001) versus 0.76% in controls (p = 0.271). Posterior diaphragm thickness (PDT) improved by 7.48% (ES = 0.282, p < 0.001) versus 0.38% (p = 0.564). Right AWMT increased by 12.7% (ES = 0.492, p < 0.001) compared to 0.10% (p = 0.872), and left AWMT increased by 9.93% (ES = 0.395, p < 0.001) versus 2.64% (p = 0.014). FLD improved by 11.79% (ES = 0.959, p < 0.001) in the IMT group, while the control group showed no meaningful change (−0.13%, p = 0.847). Conclusions: A short-term IMT protocol significantly enhanced diaphragm and AWMT and reduced liver fat in elderly women. These findings support the use of IMT as a simple, non-invasive intervention to preserve musculoskeletal and metabolic health in aging populations. Full article
(This article belongs to the Special Issue Physical Therapy: A New Perspective)
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13 pages, 1990 KB  
Article
Agreement Between a Pre-Markered T-Shirt and Manual Marker Placement for Opto-Electronic Plethysmography (OEP) Measures
by Nayani G. Adhikari, Eugénie Hunsicker, Matthew T. G. Pain, John W. Dickinson and Samantha L. Winter
Sensors 2025, 25(14), 4464; https://doi.org/10.3390/s25144464 - 17 Jul 2025
Viewed by 870
Abstract
Opto-electronic plethysmography (OEP) is used to measure chest wall compartment volumes and their synchronisation. Breathing pattern disorder (BPD) can be distinguished using the phase angles between these chest wall compartments during exercise. However, the time taken to manually place the standard OEP model [...] Read more.
Opto-electronic plethysmography (OEP) is used to measure chest wall compartment volumes and their synchronisation. Breathing pattern disorder (BPD) can be distinguished using the phase angles between these chest wall compartments during exercise. However, the time taken to manually place the standard OEP model involving 89 reflective markers is high during clinical application. The purpose of this study was to investigate the use of a pre-markered T-shirt instead of markers applied directly to the skin at rest, during different exercise intensities and recovery. Thirty-nine healthy participants (24 male, 15 female) aged 18–40 years performed an incremental cycling test with the skin-mounted OEP marker set. Participants then repeated the same cycling test with a pre-markered T-shirt. Across all test conditions, the T-shirt showed a strong level of agreement (Intraclass correlation coefficient (ICC) ≥ 0.9) with the standard breath-by-breath (BbB) gas analyser. Moreover, ICC values exceeded 0.8 for compartment contributions across all test conditions, indicating excellent agreement with the skin-mounted markers. The phase angles between compartments showed the best agreement during the moderate exercise level (0.6 < ICC < 0.8). In conclusion, the pre-markered T-shirt presents a viable solution for the quick monitoring of breathing patterns, as well as an effective tool in diagnosing BPD during exercise. Full article
(This article belongs to the Special Issue Smart Sensing for Healthcare Transformation)
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21 pages, 899 KB  
Article
Cervical Spine Range of Motion Reliability with Two Methods and Associations with Demographics, Forward Head Posture, and Respiratory Mechanics in Patients with Non-Specific Chronic Neck Pain
by Petros I. Tatsios, Eirini Grammatopoulou, Zacharias Dimitriadis, Irini Patsaki, George Gioftsos and George A. Koumantakis
J. Funct. Morphol. Kinesiol. 2025, 10(3), 269; https://doi.org/10.3390/jfmk10030269 - 16 Jul 2025
Cited by 3 | Viewed by 3688
Abstract
Objectives: New smartphone-based methods for measuring cervical spine range of motion (CS-ROM) and posture are emerging. The purpose of this study was to assess the reliability and validity of three such methods in patients with non-specific chronic neck pain (NSCNP). Methods: [...] Read more.
Objectives: New smartphone-based methods for measuring cervical spine range of motion (CS-ROM) and posture are emerging. The purpose of this study was to assess the reliability and validity of three such methods in patients with non-specific chronic neck pain (NSCNP). Methods: The within-day test–retest reliability of CS-ROM and forward head posture (craniovertebral angle-CVA) was examined in 45 patients with NSCNP. CS-ROM was simultaneously measured with an accelerometer sensor (KFORCE Sens®) and a mobile phone device (iHandy and Compass apps), testing the accuracy of each and the parallel-forms reliability between the two methods. For construct validity, correlations of CS-ROM with demographics, lifestyle, and other cervical and thoracic spine biomechanically based measures were examined in 90 patients with NSCNP. Male–female differences were also explored. Results: Both methods were reliable, with measurements concurring between the two devices in all six movement directions (intraclass correlation coefficient/ICC = 0.90–0.99, standard error of the measurement/SEM = 0.54–3.09°). Male–female differences were only noted for two CS-ROM measures and CVA. Significant associations were documented: (a) between the six CS-ROM measures (R = 0.22–0.54, p < 0.05), (b) participants’ age with five out of six CS-ROM measures (R = 0.23–0.40, p < 0.05) and CVA (R = 0.21, p < 0.05), (c) CVA with two out of six CS-ROM measures (extension R = 0.29, p = 0.005 and left-side flexion R = 0.21, p < 0.05), body mass (R = −0.39, p < 0.001), body mass index (R = −0.52, p < 0.001), and chest wall expansion (R = 0.24–0.29, p < 0.05). Significantly lower forward head posture was noted in subjects with a high level of physical activity relative to those with a low level of physical activity. Conclusions: The reliability of both CS-ROM methods was excellent. Reductions in CS-ROM and increases in CVA were age-dependent in NSCNP. The significant relationship identified between CVA and CWE possibly signifies interconnections between NSCNP and the biomechanical aspect of dysfunctional breathing. Full article
(This article belongs to the Section Kinesiology and Biomechanics)
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25 pages, 2026 KB  
Review
Mapping the Fat: How Childhood Obesity and Body Composition Shape Obstructive Sleep Apnoea
by Marco Zaffanello, Angelo Pietrobelli, Giorgio Piacentini, Thomas Zoller, Luana Nosetti, Alessandra Guzzo and Franco Antoniazzi
Children 2025, 12(7), 912; https://doi.org/10.3390/children12070912 - 10 Jul 2025
Cited by 3 | Viewed by 2436
Abstract
Background/Objectives: Childhood obesity represents a growing public health concern. It is closely associated with obstructive sleep apnoea (OSA), which impairs nocturnal breathing and significantly affects neurocognitive and cardiovascular health. This review aims to analyse differences in fat distribution, anthropometric parameters, and [...] Read more.
Background/Objectives: Childhood obesity represents a growing public health concern. It is closely associated with obstructive sleep apnoea (OSA), which impairs nocturnal breathing and significantly affects neurocognitive and cardiovascular health. This review aims to analyse differences in fat distribution, anthropometric parameters, and instrumental assessments of paediatric OSA compared to adult OSA to improve the diagnostic characterisation of obese children. Methods: narrative review. Results: While adenotonsillar hypertrophy (ATH) remains a primary cause of paediatric OSA, the increasing prevalence of obesity has introduced distinct pathophysiological mechanisms, including fat accumulation around the pharynx, reduced respiratory muscle tone, and systemic inflammation. Children exhibit different fat distribution patterns compared to adults, with a greater proportion of subcutaneous fat relative to visceral fat. Nevertheless, cervical and abdominal adiposity are crucial in increasing upper airway collapsibility. Recent evidence highlights the predictive value of anthropometric and body composition indicators such as neck circumference (NC), neck-to-height ratio (NHR), neck-to-waist ratio (NWR), fat-to-muscle ratio (FMR), and the neck-to-abdominal-fat percentage ratio (NAF%). In addition, ultrasound assessment of lateral pharyngeal wall (LPW) thickness and abdominal fat distribution provides clinically relevant information regarding anatomical contributions to OSA severity. Among imaging modalities, dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), and air displacement plethysmography (ADP) have proven valuable tools for evaluating body fat distribution. Conclusions: Despite advances in the topic, a validated predictive model that integrates these parameters is still lacking in clinical practice. Polysomnography (PSG) remains the gold standard for diagnosis; however, its limited accessibility underscores the need for complementary tools to prioritise the identification of children at high risk. A multimodal approach integrating clinical, anthropometric, and imaging data could support the early identification and personalised management of paediatric OSA in obesity. Full article
(This article belongs to the Section Translational Pediatrics)
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23 pages, 5089 KB  
Review
Optimizing Airway Function Through Craniofacial and Cervical Manipulations and Emergency-Anesthesia Maneuvers: Applications in Airway Function Enhancement, Pneumonia, and Asthma—Narrative Review
by Jason Park, Luz Benitez, Amethyst Hamanaka, Ghulam Husain Abbas, Emmanuel Faluade, Sjaak Pouwels and Jamie Eller
J. Clin. Med. 2025, 14(13), 4494; https://doi.org/10.3390/jcm14134494 - 25 Jun 2025
Cited by 1 | Viewed by 2712
Abstract
Background: Even with advanced management involving pharmacologic and ventilatory strategies, respiratory dysfunction increases morbidity and reduces the quality of life. This narrative review examines how craniofacial and cervical manipulative interventions—including nasomaxillary skeletal expansion, breathing re-education, and structural techniques—may holistically optimize airway function by [...] Read more.
Background: Even with advanced management involving pharmacologic and ventilatory strategies, respiratory dysfunction increases morbidity and reduces the quality of life. This narrative review examines how craniofacial and cervical manipulative interventions—including nasomaxillary skeletal expansion, breathing re-education, and structural techniques—may holistically optimize airway function by enhancing neurological and lymphatic dynamics, modulating vagal tone, reducing pharyngeal collapsibility, and supporting immune regulation across diverse clinical settings. Objectives: To explore manual techniques that influence respiratory and autonomic function and to evaluate their reported clinical efficacy and supporting evidence, particularly in the context of airway disorders such as asthma and pneumonia. Methods: A narrative review of the literature from PubMed and Google Scholar was conducted using search terms related to airway function and osteopathic manipulative techniques (OMTs). The inclusion criteria spanned 2010–2025 English-language peer-reviewed full-text articles on airway function, OMT, and emergency airway maneuvers. Clinical trials, observational studies, and reviews were included; non-peer-reviewed content and animal studies (unless mechanistically relevant) were excluded. Chapman’s reflexes related to respiratory function were incorporated to highlight somatic–visceral correlations. Key Findings: The techniques reviewed included frontal lift, vomer manipulation, maxillary and zygomatic balancing, and cervical adjustments. Thoracic OMT methods, such as diaphragm doming and lymphatic pump techniques, were also addressed. Emergency techniques, such as the BURP and Larson maneuvers, prone positioning, and high-frequency chest wall oscillation, were presented as comparative strategies to OMTs for acute airway management. Conclusions: Craniofacial and cervical manipulations can be a promising adjunct for enhancing airway function. However, the current literature displays heterogeneity and lack of large-scale randomized trials, which emphasize the necessity for standardized research and the establishment of clinical guidelines with the collected evidence. Full article
(This article belongs to the Section Respiratory Medicine)
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25 pages, 3693 KB  
Article
Triangular Fuzzy Finite Element Solution for Drought Flow of Horizontal Unconfined Aquifers
by Christos Tzimopoulos, Nikiforos Samarinas, Kyriakos Papadopoulos and Christos Evangelides
Hydrology 2025, 12(6), 128; https://doi.org/10.3390/hydrology12060128 - 23 May 2025
Cited by 1 | Viewed by 1070
Abstract
In this paper, a novel approximate triangular fuzzy finite element method (FEM) is proposed to solve the one-dimensional second-order unsteady nonlinear fuzzy partial differential Boussinesq equation. The physical problem concerns the case of the drought flow of a horizontal unconfined aquifer with a [...] Read more.
In this paper, a novel approximate triangular fuzzy finite element method (FEM) is proposed to solve the one-dimensional second-order unsteady nonlinear fuzzy partial differential Boussinesq equation. The physical problem concerns the case of the drought flow of a horizontal unconfined aquifer with a limited breath B and special boundary conditions: (a) at x = 0, the water level is equal to zero, and (b) at x = B, the flow rate is equal to zero due to the presence of an impermeable wall. The initial water table is assumed to be curvilinear, following the form of an inverse incomplete beta function. To account for uncertainties in the system, the hydraulic parameters—hydraulic conductivity (K) and porosity (S)—are treated as fuzzy variables, considering sources of imprecision such as measurement errors and human-induced uncertainties. The performance of the proposed fuzzy FEM scheme is compared with the previously developed orthogonal fuzzy FEM solution as well as with an analytical solution. The results are in close agreement with those of the other methods, with the mean error of the analytical solution found to be equal to 1.19·106. Furthermore, the possibility theory is applied and fuzzy estimators constructed, leading to strong probabilistic interpretations. These findings provide valuable insights into the hydraulic properties of unconfined aquifers, aiding engineers and water resource managers in making informed and efficient decisions for sustainable hydrological and environmental planning. Full article
(This article belongs to the Topic Advances in Groundwater Science and Engineering)
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12 pages, 11070 KB  
Article
Bilateral Stylopharyngeus Transection Alters Respiratory Airflow in Conscious Rats
by Eriko Hamada, Thomaz Fleury Curado, Kingman Strohl and Yee-Hsee Hsieh
Surg. Tech. Dev. 2025, 14(2), 15; https://doi.org/10.3390/std14020015 - 7 May 2025
Viewed by 1156
Abstract
Background/Objectives: Upper airway patency is a key pathophysiological factor in obstructive sleep apnea (OSA). Research has primarily focused on the role of the genioglossus muscle in maintaining airway patency in OSA. However, hypoglossal nerve stimulation (HNS) therapy, which activates the genioglossus muscle, has [...] Read more.
Background/Objectives: Upper airway patency is a key pathophysiological factor in obstructive sleep apnea (OSA). Research has primarily focused on the role of the genioglossus muscle in maintaining airway patency in OSA. However, hypoglossal nerve stimulation (HNS) therapy, which activates the genioglossus muscle, has been associated with poor outcomes in patients with lateral oropharyngeal collapse. The stylopharyngeus muscle is an upper airway dilator muscle that supports the lateral pharyngeal wall. Its role in maintaining upper airway patency and its effect on normal respiratory airflow is unclear. We hypothesize that bilateral transection of the stylopharyngeus muscles disrupts normal breathing. Currently, no animal model depicting lateral pharyngeal collapse has been reported. This study aims to introduce a novel rodent model with bilateral transection of the stylopharyngeus muscles to examine its effect on respiratory airflow and tracing. Methods: Adult male Sprague Dawley rats were divided into two groups: (1) bilateral stylopharyngeus muscle transection (n = 4) and (2) sham surgery (n = 2). Under anesthesia, the stylopharyngeus muscle was transected bilaterally in the transection group, while only exposure of the muscle was performed in the sham group. Respiratory airflow was measured using whole-body plethysmography before and after surgery, and airflow tracings were analyzed. Results: Significant alterations in respiratory airflow and tracings, particularly a flattening in inspiratory flow and sharp expiratory peaks, were observed on the first post-operative day in the transection group. The flattening of the inspiratory flow persisted over 3 days. No significant changes were noted in the sham group. Conclusions: Bilateral stylopharyngeus muscle transection alters normal airflow in a conscious rodent model, supporting the hypothesis that stylopharyngeus muscle plays a vital role in shaping respiratory airflow. The flattening of the inspiratory airflow is an indication of flow limitations through the upper airway patency due to the loss of stylopharyngeus function. Full article
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