Search Results (73)

The biomarker carcinoembryonic antigen (CEA) plays an important role in the diagnosis and monitoring of cancer, like breast, surveillance, colon, and liver cancer. The highly sensitive surface plasmon resonance (SPR) sensor presented in this work uses two-dimensional (2D) materials: BP/graphene, and the franckeite layer integrated in a Kretschmann configuration. The sensor structure, which includes a copper (Cu) layer and a CaF₂ prism, is intended to detect CEA in aqueous solutions with high accuracy. The proposed sensor’s performance was assessed using the transfer matrix method (TMM), with particular attention paid to important metrics like sensitivity, figure of merit (FoM), detection accuracy (DA), and penetration depth (PD). The proposed sensor achieved a sensitivity of 307.50 deg/RIU and a FoM of 61.62/RIU at a R_min value of 4.20 × 10⁻⁵ a.u. at a 40 nm Cu thickness, operating at a wavelength of 633 nm. The maximum sensitivity of 348.07 deg/RIU was achieved at 47 nm Cu thickness with BP layer, while the graphene layer yielded maximum sensitivity of 314.32 deg/RIU at the same Cu thickness. The results show that adding 2D layered materials to symmetric SPR sensors greatly improves detection performance, providing a promising foundation for the detection of clinical biomarkers in the future. Full article

Two-dimensional (2D) nanomaterials have attracted growing attention in the field of oral medicine due to their unique physicochemical properties, including high surface area, adjustable surface chemistry, and exceptional biocompatibility. In recent years, a variety of 2D materials, including graphene-based nanomaterials, black phosphorus nanosheets, MXenes, layered double hydroxides (LDHs), transition metal dichalcogenides (TMDs), 2D metal–organic frameworks (MOFs), and polymer-based nanosheets, have been extensively explored for the treatment of oral diseases. These functional materials demonstrate multiple therapeutic capabilities, such as antibacterial activity, reactive oxygen species (ROS) scavenging, anti-inflammatory modulation, and promotion of tissue regeneration. In this review, we systematically summarize the recent advances of 2D nanomaterials in the treatment of common oral diseases such as dental caries, periodontitis, oral cancer and peri-implantitis. The underlying therapeutic mechanisms are also summarized. Challenges for clinical translation of these nanomaterials and the possible solutions are discussed as well. Full article

The main soil type in the Sanjiang Plain of Northeast China, dryland albic soil is of great significance for studying nutrient distribution characteristics. This study focuses on 852 Farm in the typical dryland albic soil area of the Sanjiang Plain, using a combination of paired t-test, geostatistics, correlation analysis, and principal component analysis to systematically reveal the spatial differentiation of soil nutrients in the black soil layer and white clay layer of dryland albic soil, and to clarify the impact mechanism of plow layer nutrient characteristics on crop productivity. The results show that the nutrient content order in both the black and white clay layers is consistent: total potassium (TK) > organic matter (OM) > total nitrogen (TN) > total phosphorus (TP) > alkali-hydrolyzable nitrogen (HN) > available potassium (AK) > available phosphorus (AP). Both layers exhibit a spatial pattern of overall consistency and local differentiation, with spatial heterogeneity dominated by altitude gradients—nutrient content increases with decreasing altitude. Significant differences exist in nutrient content and distribution between the black and white clay layers, with the comprehensive fertility of the black layer being significantly higher than that of the white clay layer, particularly for TN, TP, TK, HN, and OM contents (effect size > 8). NDVI during the full maize growth period is significantly positively correlated with TP, TN, AK, AP, and HN, and the NDVI dynamics (first increasing. then decreasing) closely align with the peak periods of available nitrogen/phosphorus and crop growth cycles, indicating a strong coupling relationship between vegetation biomass accumulation and nutrient availability. These findings provide important references for guiding rational fertilization, agricultural production layout, and ecological environmental protection, contributing to the sustainable utilization of dryland albic soil resources and sustainable agricultural development. Full article

Cultivated land quality is a key factor in ensuring sustainable agricultural development. Exploring differences in cultivated land quality under distinct cropping systems is essential for developing targeted improvement strategies. This study takes place in Shenyang City—located in the typical black soil region of Northeast China—as a case area to construct a cultivated land quality evaluation system comprising 13 indicators, including organic matter, effective soil layer thickness, and texture configuration. A minimum data set (MDS) was separately extracted for paddy and upland fields using principal component analysis (PCA) to conduct a comprehensive evaluation of cultivated land quality. Additionally, an obstacle degree model was employed to identify the limiting factors and quantify their impact. The results indicated the following. (1) Both MDSs consisted of seven indicators, among which five were common: ≥10 °C accumulated temperature, available phosphorus, arable layer thickness, irrigation capacity, and organic matter. Parent material and effective soil layer thickness were unique to paddy fields, while landform type and soil texture were unique to upland fields. (2) The cultivated land quality index (CQI) values at the sampling point level showed no significant difference between paddy (0.603) and upland (0.608) fields. However, their spatial distributions diverged significantly; paddy fields were dominated by high-grade land (Grades I and II) clustered in southern areas, whereas uplands were primarily of medium quality (Grades III and IV), with broader spatial coverage. (3) Major constraint factors for paddy fields were effective soil layer thickness (21.07%) and arable layer thickness (22.29%). For upland fields, the dominant constraints were arable layer thickness (27.57%), organic matter (25.40%), and ≥10 °C accumulated temperature (23.28%). Available phosphorus and ≥10 °C accumulated temperature were identified as shared constraint factors affecting quality classification in both systems. In summary, cultivated land quality under different cropping systems is influenced by distinct limiting factors. The construction of cropping-system-specific MDSs effectively improves the efficiency and accuracy of cultivated land quality assessment, offering theoretical and methodological support for land resource management in the black soil regions of China. Full article

Few-layer black phosphorus (BP) holds significant potential for next-generation electronics due to its tunable bandgap and high carrier mobility. The layer modulation of BP is essential in the applications of electronic devices ascribed to its thickness-dependent electronic properties. However, precisely controlling its thickness still presents a challenge for optimizing performance. In this study, we demonstrate that BP can be precisely thinned when exposed to dry oxygen (40% humidity, low oxygen concentration) in a dark environment, which is different from that exposed to humid oxygen (100% humidity, low oxygen concentration) without light illumination. The thinned BP not only demonstrates enhanced stability but also exhibits significant improvements in its electrical properties. The variation in bandgap from 0.3 to 2 eV, resulting in the I_ON/I_OFF ratio increased from 10³ to 10⁶, and the hole mobility improved from 235 cm² V⁻¹ s⁻¹ to 851 cm² V⁻¹ s⁻¹, was ascribed to the layer-by-layer thinning and p-type doping effects induced by the formed P_xO_y. Our finding demonstrates significant potential of BP in future nanoelectronic and optoelectronic applications. Full article

Black phosphorus is a promising thermoelectric (TE) material because of its high Seebeck coefficient and high electrical conductivity. In this work, the TE performance of bulk black phosphorus and single-layer phosphorene under uniaxial strain is studied using first-principles calculations and Boltzmann transport theory. The results show relatively excellent TE performance along the armchair direction for both black phosphorus and phosphorene in our study. However, high lattice thermal conductivity is the key adverse factor for further enhancing the TE performance of phosphorus. The ZT value can only reach up to 0.97 and 0.73 for n- and p-type black phosphorus at 700 K, respectively. Owing to quantum size effects, black phosphorene has lower lattice thermal conductivity than black phosphorus. At the same time, two-dimensional (2D) phosphorene exhibits increased electronic energy compared with bulk black phosphorus, resulting in a larger bandgap and reduced electrical conductivity due to the quantum confinement effect. Thus, the TE performance of n-type phosphorene can be partially improved, and the ZT value reaches up to 1.41 at 700 K. However, the ZT value decreases from 0.73 to 0.70 for p-type phosphorene compared with bulk phosphorus at 700 K. To further improve the TE performance of phosphorene, a tensile strain is applied along the armchair direction. Subsequent work indicates that uniaxial strain can further optimize phosphorene’s TE properties by tuning hole relaxation time to improve electrical conductivity. Strikingly, the ZT values exceed 1.7 for both n- and p-type phosphorene under 4.5% tensile strain along the armchair direction at 700 K because of increased electrical conductivity and decreased lattice thermal conductivity. Full article

In this paper, we propose an innovative approach based on the wavelength optimization of a light source for a simple, high-performance surface plasmon resonance (SPR) sensor utilizing comprehensive reflectance analysis in the angular domain. The proposed structure consists of a glass substrate, an adhesion layer of titanium dioxide, a silver plasmonic layer, and a 2D material. Analysis is performed in the Kretschmann configuration for liquid analyte sensing. Sensing parameters such as the refractive index (RI) sensitivity, the reflectance minimum, and the figure of merit (FOM) are investigated in the first step of this study as a function of the thickness of the silver layer together with the RI of a coupling prism. Next, utilizing the results offering a fused silica prism, the thickness of the silver layer and the wavelength of the light source are optimized for the structure with the addition of a 2D material, black phosphorus (BP), which is studied along different principal directions, the zigzag and armchair directions. In addition, a new approach of adjusting the source wavelength using a one-dimensional photonic crystal combined with an LED, is presented. Based on this analysis, for the reference structure at a wavelength of 632.8 nm, the optimized silver layer thickness is 50 nm, and the achieved RI sensitivity ranges from 193.9 to 251.5 degrees per RI unit (deg/RIU), with the highest FOM reaching 52.3 RIU⁻¹. In addition, for the modified structure with BP, the achieved RI sensitivity varies in the range of 269.1–351.2 deg/RIU at the optimized wavelength of 628 nm, with the highest FOM reaching 44.7 RIU⁻¹ for the zigzag direction. Due to the optimization and adjusting the wavelength of the source, the results obtained for the proposed SPR structure could have significant implications for the development of more sensitive and efficient sensors employing a simple plasmonic structure. Full article

This study presents a numerical investigation of surface plasmon resonance (SPR) sensors based on multilayer configurations incorporating BK7, silver, silicon nitride (Si₃N₄), and black phosphorus (BP). Using the transfer matrix method, the optical performance of four architectures was evaluated under refractive index perturbations consistent with values reported in prior theoretical and experimental studies. The sensor response was characterized through metrics such as angular sensitivity, resonance shift, full width at half maximum, attenuation, and derived figures including detection accuracy and limit of detection. Parametric optimization was performed for the thickness of each functional layer to enhance sensing performance. Among all configurations, those incorporating both Si₃N₄ and BP demonstrated the highest angular sensitivity, reaching up to 394.46°/RIU. These enhancements were accompanied by increased attenuation and spectral broadening, revealing trade-offs in sensor design. The results, based entirely on numerical modeling, provide a comparative framework for guiding SPR sensor optimization under idealized optical conditions. Full article

This study investigated the effects of organic amendments (straw return, organic fertilizer, biochar, and their combinations) on grain yield, quality, and soil biochemical characteristics in black wheat. A two-year field experiment (2022–2024) was conducted with five treatments: F (conventional fertilization), FS (F + full straw return), FO (F + 3 t/ha organic fertilizer), FB (F + 3 t/ha biochar), and FSOB (F + full straw + 3 t/ha organic fertilizer + 3 t/ha biochar). FSOB achieved the highest yield, increasing by 17.3% over F due to a higher spike number and 1000-grain weight. Grain protein increased by 9.0% and 9.4% under FS and FO, respectively. Straw addition also raised gluten by 6.8%. Soil analysis revealed that integrated organic management significantly increased the contents of organic matter (by 23.1%), total nitrogen (by 46.0%), and available phosphorus (by 73.5%) in the 0–20 cm soil layer. It also promoted beneficial microbial taxa, including Actinobacteria (+11.2%) and Proteobacteria (+0.6%), compared to conventional fertilization. These findings suggest that strategic integration of organic amendments can enhance black wheat productivity and grain quality by improving soil fertility and microbial functionality, thereby supporting sustainable cropping systems. Full article

This study presents a black phosphorus-based surface plasmon resonance (SPR) biosensor for malaria detection, integrating silicon nitride (Si₃N₄) and single-stranded DNA (ssDNA) to enhance sensitivity and molecular recognition. The biosensor configurations were optimized through numerical simulations, evaluating metal thickness, dielectric layer thickness, and the number of black phosphorus layers to achieve maximum performance. The optimized system (Opt-Sys₄) exhibited high sensitivity (464.4°/RIU for early-stage malaria) and improved detection accuracy, outperforming conventional SPR sensors. Performance was assessed across malaria progression stages, demonstrating a clear resonance shift, increased attenuation, and enhanced biomolecular interactions. Key metrics, including the figure of merit, limit of detection, and comprehensive sensitivity factor, confirmed the sensor’s superior performance. Comparative analysis against state-of-the-art SPR biosensors further validated their capability for highly sensitive and specific malaria detection. These findings establish a promising plasmonic biosensing platform for early malaria diagnosis, potentially improving disease management in resource-limited settings. Full article

Black soils refer to soils with black, thick upper layers containing 0.6% or more soil organic carbon in the tropical region. This high organic carbon content makes these soils essential for climate change control and food production. In Indonesia, black soils are found under forests, shrublands, and grasslands in tropical monsoon and savannah climates. Land clearing for agricultural uses will change black soil properties; however, knowledge of change (level, direction, and sensitivity) is limited. Meanwhile, soil surveying records land-use types and collects soil samples, resulting in voluminous legacy soil data. This study aimed to compare the mean difference in soil properties between two land-cover/use types. We used 142 black soil datasets containing legacy data on particle size distribution (sand, silt, clay), pH, soil organic carbon (SOC), total nitrogen (TN), available P₂O₅ (AP), and exchangeable cations (Ca, Mg, K, Na). We calculated the Hedges’s g-index for effect size assessment and performed a Welch’s t-test for significant differences. The results show that, compared to the forest, the agricultural dryland and monoculture home gardens have a large effect size and trigger changes in many soil properties. In contrast, mixed home gardens and paddy fields have a small effect size. In decreasing order, the black soil properties sensitive to change are TN > SOC = exchangeable K > exchangeable Mg = available phosphorus = pH = exchangeable Na > sand = silt = clay > exchangeable Ca. The results suggest that a combination of home gardens and paddy fields better supports food security and mitigates climate change in black soils. In addition, the legacy soil data can be used to monitor soil property changes. Full article

To assess the effects of prolonged no-tillage practices on soil health and crop output, an 18-year field study was carried out in the black soil region of Northeast China. We investigated the variations in soil physicochemical properties, bacterial community structure, and soybean yield under different no-tillage (NT) durations from year 10 to 18 and conventional tillage (CT) treatments for 18 years. The findings indicated that the 18-year no-tillage (NT18) treatment resulted in significantly greater levels of soil organic matter, total nitrogen, and available phosphorus—18.3%, 30.4%, and 65.8% higher, respectively (p < 0.05)—compared to the traditional tillage (CT18) treatment. In the 0–30 cm soil layer, the relative abundance of Acidobacteriota had risen with the duration of no-tillage, whereas Proteobacteria, Gemmatimonadota, and Verrucomicrobiota had shown a decline. In addition, no-tillage treatments increased network complexity, with longer durations of no-tillage leading to higher levels of complexity. Soybean yield increased by 8.5% under NT18 compared to CT18 (p < 0.05). These findings provide insights into the interaction between no-tillage treatments and soil bacterial microbial communities within the black soil region, thereby establishing a solid foundation for developing efficient, ecological, and sustainable conservation tillage systems in Northeast China. Full article

The CsPbBr₃ perovskite exhibits strong environmental stability under light, humidity, temperature, and oxygen conditions. However, in all-inorganic perovskite solar cells (PSCs), interface defects between the carbon electrode and CsPbBr₃ limit the carrier separation and transfer rates. We used black phosphorus (BP) nanosheets as the hole transport layer (HTL) to construct an all-inorganic carbon-based CsPbBr₃ perovskite (FTO/c-TiO₂/m-TiO₂/CsPbBr₃/BP/C) solar cell. BP can enhance hole extraction capabilities and reduce carrier recombination by adjusting the interface contact between the perovskite and the carbon layer. Due to the coordination of the energy structure related to interface charge extraction and transfer, BP, as a new type of hole transport layer for all-inorganic CsPbBr₃ solar cells, achieves a power conversion efficiency (PCE) that is 1.43% higher than that of all-inorganic carbon-based CsPbBr₃ perovskite solar cells without a hole transport layer, reaching 2.7% (Voc = 1.29 V, Jsc = 4.60 mA/cm², FF = 48.58%). In contrast, the PCE of the all-inorganic carbon-based CsPbBr₃ perovskite solar cells without a hole transport layer was only 1.27% (Voc = 1.22 V, Jsc = 2.65 mA/cm², FF = 39.51%). The unencapsulated BP-based PSCs device maintained 69% of its initial efficiency after being placed in the air for 500 h. In contrast, the efficiency of the PSC without HTL significantly decreased to only 52% of its initial efficiency. This indicates that BP can effectively enhance the PCE and stability of PSCs, demonstrating its great potential as a hole transport material in all-inorganic perovskite solar cells. BP as the HTL for CsPbBr₃ PSCs can passivate the perovskite interface, enhance the hole extraction capability, and improve the optoelectronic performance of the device. The subsequent doping and compounding of the BP hole transport layer can further enhance its photovoltaic conversion efficiency in PSCs. Full article

Metagenomic sequencing of the microbial soil community was used to assess the effect of various nitrogen fertilizer treatments in combination with constant rice straw return to the soil in the tiller layer of Northeast China’s black paddy soil used for rice production. Here, we investigated changes in the composition, diversity, and structure of soil microbial communities in the soil treated with four amounts of nitrogen fertilizers (53, 93, 133, and 173 kg/ha) applied to the soil under a constant straw return of 7500 kg/ha, with a control not receiving N. The relationships between soil microbial community structure and soil physical and chemical properties were determined. The results showed that the available K content of the soil significantly (p < 0.05) increased in soil receiving the lowest N-fertilizer dose. When applied at high amounts, N-fertilizer changed the Chao1 and ACE indices of the soil microorganisms (p < 0.05), and the treatments resulted in significant differences in the β-diversity of the soil microorganisms. By NMDS analysis it was demonstrated that the treatment significantly affected the structure of the soil microbial communities. Redundancy analysis showed that the main physicochemical drivers behind these differences were total nitrogen, total potassium, ammonium nitrogen, total phosphorus, and available potassium. The soil microbial communities in the control treatment were negatively correlated with nitrate and ammonium nitrogen; the lowest N-fertilizer treatment produced positive correlations with total nitrogen, total potassium, and total phosphorus and negative correlations with ammonium nitrogen; the highest dose negatively correlated with total nitrogen, available potassium, available phosphorus, total phosphorus, and pH. This study showed that moderate N fertilizer application is an effective way to increase soil microbial diversity and improve soil quality. This experiment provides technical support for the application of the alternative fertilizer technology of straw return to the field and provides a theoretical basis for rational fertilization of paddy fields in a cold climate. Full article

Conservation tillage is a practice adopted worldwide to prevent soil degradation. Although there have been many studies on the impact of conservation tillage on soil quality, most studies on cultivated land in the black soil region of Northeast China are based on the physical and chemical indicators of soil. In addition, the experiment time is generally short, so there is a lack of information about long-term conservation tillage from the perspective of the physical, chemical, and biological integration of soil. A comparative analysis of the physical, chemical, and biological characteristics of soil was conducted under no-till (NT) with straw mulching and conventional tillage (CT) treatments after 19 years of field experiments. By using membership functions to normalize and render all the indicators dimensionless, and calculating the weight of each indicator through principal component analysis, the comprehensive index of soil quality can be calculated as a weighted summation. The results indicate that NT had no significant effect on soil bulk density at a soil depth of 0–20 cm. NT increased the field water-holding capacity of the 0–5 cm layer, reduced the total porosity of the 5–10 cm soil layer, and decreased the non-capillary porosity of the 0–20 cm soil layer. Compared to CT, NT significantly increased the organic carbon content of the soil in the 0–5 cm layer, comprehensively improved the total nutrient content of the soil, and significantly increased the contents of ammonium nitrogen, nitrate-nitrogen, and available phosphorus in the soil. It also significantly improved the total phosphorus content in the 5–20 cm soil layer. NT improved the microbial carbon and nitrogen content of the soil, significantly enhanced the microbial nitrogen content in the 0–5 and 5–10 cm soil layers, and reduced the bacterial species diversity in the 5–10 cm soil layer. However, the soil enzyme activities showed no significant differences between different treatments. Under the NT treatment, the evaluation of soil quality indicators, such as mean weight diameter, field water-holding capacity, non-capillary porosity, microbial biomass nitrogen, total nutrients, and available nutrients, was relatively successful. Based on the weight calculation, the organic carbon, catalase activity, fungal richness, and bacterial diversity indicators are the most important of the 22 soil quality indicators. In terms of the comprehensive index of soil fertility quality, NT increased the soil quality comprehensive index by 34.2% compared to CT. Long-term conservation tillage improved the physical, chemical, and biological properties of the soil, which significantly enhanced the quality of the black soil. Full article