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  • Article
  • Open Access
8 Citations
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13 Pages

Effect of MACC1 Genetic Polymorphisms and Environmental Risk Factors in the Occurrence of Oral Squamous Cell Carcinoma

  • Rei-Hsing Hu,
  • Chun-Yi Chuang,
  • Chiao-Wen Lin,
  • Shih-Chi Su,
  • Lun-Ching Chang,
  • Ssu-Wei Wu,
  • Yu-Fan Liu and
  • Shun-Fa Yang

MACC1 (Metastasis Associated in Colon Cancer 1) is found to regulate the hepatocyte growth factor (HGF)/Met signal pathway, and plays an important role in tumor proliferation, angiogenesis, and metastasis. However, the relationships between MACC1 SNP...