168,647 Results Found

Background: Brain age prediction from brain MRI scans and the resulting brain age gap (BAG)—the difference between predicted brain age and chronological age—is a general biomarker for a variety of neurological, psychiatric, and other dise...

Globally, there is an urgent need for solutions that can support our aging populations to live well and reduce the associated economic, social and health burdens. Implementing smart technologies within homes and communities may assist people to live...

In this article, we develop a tentative philosophy to orchestrate and support possibilities for artful ageing. This effort argues that older adults need a broader range of opportunities to explore the manifold ephemeral, non-rational, and in-between...

Asphalt mixtures age during service in the field, primarily as the result of chemical changes in the bituminous binder phase. The ageing phenomenon changes the properties of the asphalt mixture, including the stiffness modulus, the resistance to defo...

Asphalt binder is a crucial component of asphalt pavements that undergoes ageing over time, which can result in the reduced performance and deterioration of pavements. Consequently, artificial ageing methods play a significant role in providing valua...

In the last decades, the scientific interest in ageing has increased due to the progressive ageing of the global population and due to the importance of guaranteeing the elder people and the next generations a good quality of life and biopsychologica...

Ageing literature, while growing in huge volume in the past decades, is still largely dominated by frameworks and topics of frailty and decline. A shift in attention to conceptualising ageing more holistically to include psychosocial and emotional as...

Residential districts, the primary locations for older adults, struggle to satisfy the needs of the rising older population due to ageing infrastructure, etc. China has begun to focus on this issue through the popularization of approaches such as act...

Many developed countries are experiencing a marked rise in the ageing population, with a growing proportion of adults entering older age groups. Whilst the literature has focused on the design, management, and quality of services within senior living...

As part of a knowledge-transfer project consisting of a series of three talks on the topic of healthy ageing and ageing in place, we explored what participants (older adults, students, the general public, as well as professionals in architecture, urb...

The population of people living with HIV (PLWH) is growing older with an estimated 4 million over the age of 50 years, a figure which has doubled since the introduction of effective antiretroviral therapy (ART) and which is increasing globally. Despi...

In the UK, as in many other European countries, the population is growing older, and older adults are becoming more diverse. As a result, there is a mounting interest in supporting healthy ageing and independence, acknowledging the needs and agency o...

Resilience was a concept introduced in the study of responses and positive adaptation of people living in risky environments, contexts and situations that posed potential threats to normal development like poverty, disease and violence. Subsequently...

The effects of natural ageing treatment prior to artificial ageing treatment on the microstructures and mechanical properties of AA7075 Al-5.7Zn-2.6Mg-1.5Cu-0.18Cr-0.08Mn-0.05Si-0.17Fe (wt.%) aluminum alloy have been investigated. The hardness of sol...

Background: The protein that binds to retinol 4 (RBP4), is a lipocalin-family protein, secreted primarily by the adipose tissue and the liver, and has also been reported to be produced by other tissues, including the kidney. This protein mediates the...

Singapore has experienced rapid development in the past 50 years. This has presented unique challenges with regard to land space and a rapidly ageing population. The role of extrinsic factors in successful ageing is well documented, and places a degr...

Issues related to old age and ageing are an imperative topic in a society of long life, concerning everyone. Wherever possible, the age-related issues should also be adequately addressed and integrated into school education. This article gives an ove...

Religion, in the context of healing and health, has a long history reaching back through the millennia influencing, and being influenced by cultures and societies. More recently, spirituality has become more widely recognised as a real component of h...

Like with skin, both men and women—regardless of ethnicity—gradually lose satisfaction with changes in hair brought about by ageing. Especially when such transition is apparent by others, and that the hair condition has a significant role...

Demographic changes have led to an increase in older people in prisons. Whereas the rehabilitative process of younger offenders is geared towards their reintegration into the labour market, successful ageing should be a policy aim for older prisoners...

All over the world, there is an increase in the overall survival of the population and the number of elderly people. The incidence of allergic reactions is also rising worldwide. Until recently, allergies, and in particular food allergies (FAs), was...

Anti-ageing biology and medicine programmes are a focus of genetics, molecular biology, immunology, endocrinology, nutrition, and therapy. This paper discusses metabolic therapies aimed at prolonging longevity and/or health. Individual components of...

In the medical humanities, there has been a growing interest in diagnosing disease in fictional characters, particularly with the idea that characters in Charles Dickens’s novels may be suffering from diseases recognised today. However, an area...

The quest for eternal youth and immortality is as old as humankind. Ageing is an inevitable physiological process accompanied by many functional declines that are driving factors for age-related diseases. Stem cell exhaustion is one of the major hall...

Ageing is a dynamic biological process involving interconnected physiological, psychological, and social changes, making the promotion of healthy ageing a global public health priority. The World Health Organization (WHO) defines healthy ageing as th...

Definitions of healthy ageing include survival to a specific age, being free of chronic diseases, autonomy in activities of daily living, wellbeing, good quality of life, high social participation, only mild cognitive or functional impairment, and li...

Population ageing is one of humanity’s greatest achievements with the elderly who offer valuable resources and make an important contribution to the structure of our societies. At the same time, this ageing population poses great challenges, as...

This article analyses the influence of workforce ageing on labour productivity in Europe. This question is relevant because of the impact it may have on economic activity, social security systems sustainability and the wellbeing of the population. Th...

It is believed that postponing ageing is more effective and less expensive than the treatment of particular age-related diseases. Compounds which could delay symptoms of ageing, especially natural products present in a daily diet, are intensively stu...

This article explores the transformative potential of Artful Ageing as a conceptual framework for enriching experiences in later life. By synthesising Manning’s theory of minor gestures with Basting’s creative care approach, the article d...

Impairment of vascular function, in particular endothelial dysfunction and large elastic artery stiffening, represents a major link between ageing and cardiovascular risk. Clinical and experimental studies identified numerous mechanisms responsible f...

Branching processes are stochastic models describing the evolution of populations in which individuals reproduce and die independently over time. In the classical setting, an individual’s reproductive capacity is fixed throughout its lifetime....

Active ageing has been discussed in international political organisations and among researchers as a major means for combatting the challenges of demographic ageing. This study aims to make a critical-theoretical and empirical assessment of the activ...

Background: CCL-11 (eotaxin) is a chemokine with an important role in allergic conditions. Recent evidence indicates that CCL-11 plays a role in brain disorders as well. This paper reviews the associations between CCL-11 and aging, neurodegenerative,...

Mitochondrial dysfunction is associated with ageing, but the detailed causal relationship between the two is still unclear. We review the major phenomenological manifestations of mitochondrial age-related dysfunction including biochemical, regulatory...

Human ageing is a complex and integrated gradual deterioration of cellular processes. There are nine major hallmarks of ageing, that include changes in DNA repair and DNA damage response, telomere shortening, changes in control over the expression an...

Age studies scholars have long noted problems with using a tsunami metaphor to describe population ageing. Age-friendly offers a new way to respond to an increase in older adults. Though critical gerontologists identify the related movement’s limits,...

Periodontitis is a chronic inflammatory disease with a high incidence and severity in the elderly population, making it a significant public health concern. Ageing is a primary risk factor for the development of periodontitis, exacerbating alveolar b...

The activity of the thyroid gland diminishes during ageing, but a certain tissue reserve of T3 and its metabolites is maintained. This reserve is thought to play a regulatory role in energy homeostasis during ageing. This review critically assesses t...

In this paper, the authors seek to discuss some of the complexities involved in cross-cultural working in relation to the communication and management of pain in older people. Specifically, the paper addresses the culture construction of ageing and h...

Acute inflammation is a physiological response to injury or infection, with a cascade of steps that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal wounds. However, chronic inflammation arising from the continu...

Large scale testing of newly developed Li-ion cells is associated with high costs for the interested parties, and ideally, testing time should be kept to a minimum. In this work, an ageing model was developed and trained with real data from a large-s...

Recent advancements in the Internet of Things (IoT) and artificial intelligence (AI) are unlocking transformative opportunities across society. One of the most critical challenges addressed by these technologies is the ageing population, which presen...

Skin ageing is the result of a loss of cellular function, which can be further accelerated by external factors. Mitochondria have important roles in skin function, and mitochondrial damage has been found to accumulate with age in skin cells, but also...

Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an in...

This work addresses the durability of structural epoxy adhesives and carbon fibre reinforced polymer (CFRP) laminates typically used in strengthening of existing reinforced concrete structures exposed to natural ageing. The experimental program inclu...

A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals. One exciting novel strategy that has emerged...

The ageing population has grown quickly in the last half century with increased longevity and declining birth rate. This presents challenges to health services and the wider society. This review paper considers different aspects (e.g., physical, ment...

The skin, the largest organ of the human body, plays numerous essential roles, including protection against environmental hazards and the regulation of body temperature. The processes of skin homeostasis and ageing are complex and influenced by many...

Society is ageing and the higher number of senior citizens in the total population is a challenge for society and often perceived as a burden. Negative images of old age can lead to ageism and poorer healthcare for older people. The younger generatio...