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Keywords = aesthetic assessment

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22 pages, 3304 KiB  
Article
The Mechanism by Which Colour Patch Characteristics Influence the Visual Landscape Quality of Rhododendron simsii Landscape Recreational Forests
by Yan Liu, Juyang Liao, Yaqi Huang, Qiaoyun Li, Linshi Wu, Xinyu Yi, Ling Wang and Chan Chen
Horticulturae 2025, 11(8), 898; https://doi.org/10.3390/horticulturae11080898 - 3 Aug 2025
Viewed by 109
Abstract
Landscape quality and the productivity of Rhododendron simsii are directly related to the maintenance of ecological functions in the alpine region. The specific relationship between the spatial pattern of colour patches and the visual quality of R. simsii landscape recreational forests has been [...] Read more.
Landscape quality and the productivity of Rhododendron simsii are directly related to the maintenance of ecological functions in the alpine region. The specific relationship between the spatial pattern of colour patches and the visual quality of R. simsii landscape recreational forests has been insufficiently explored. In this study, we constructed a model of the relationship between landscape colour patches and the aesthetic value of such a forest, analysing the key factors driving changes in its landscape quality. A total of 1549 participants were asked to assess 16 groups of landscape photographs. The results showed that variations in perceived aesthetic quality were stimulated by colour patch dynamics and spatial heterogeneity. Utilising structural equation modelling (SEM), we identified key indicators synergistically influencing aesthetic quality, including the area percentage, shape, and distribution of colour patches, which demonstrated strong explanatory power (R2 = 0.83). The SEM also revealed that the red patch area, mean perimeter area ratio, and separation index are critical latent variables with standardised coefficients of 0.54, 0.65, and 0.62, respectively. These findings provide actionable design strategies: (1) optimising chromatic contrast through high-saturation patches, (2) controlling geometric complexity, and (3) improving spatial coherence. These results advance the theoretical framework for landscape aesthetic evaluation and offer practical guidance for landscape recreational forest management. Full article
(This article belongs to the Section Floriculture, Nursery and Landscape, and Turf)
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17 pages, 3103 KiB  
Article
Long-Term Performance of Feldspathic and Lithium Disilicate Restorations in Pediatric Anterior Dental Trauma
by Sorin Gheorghe Mihali, Șerban Talpoș, Dan Loloș, Bogdan Antonio Loloș, Andreea Raissa Hojda and Loredana Mitariu
Children 2025, 12(8), 1019; https://doi.org/10.3390/children12081019 - 1 Aug 2025
Viewed by 166
Abstract
Background/Objectives: Anterior dental trauma in adolescents presents complex restorative challenges due to ongoing craniofacial development and high aesthetic expectations. This study evaluated the long-term clinical performance of feldspathic ceramic veneers and lithium disilicate crowns used in the anterior region following dental trauma [...] Read more.
Background/Objectives: Anterior dental trauma in adolescents presents complex restorative challenges due to ongoing craniofacial development and high aesthetic expectations. This study evaluated the long-term clinical performance of feldspathic ceramic veneers and lithium disilicate crowns used in the anterior region following dental trauma in adolescents. Methods: A total of 209 restorations were placed in 85 adolescents (50 females, 35 males), aged 11.1–17.9 years (mean age: 15.1 years). Of these, 144 were lithium disilicate crowns, and 65 were feldspathic ceramic veneers. All restorations were fabricated using minimally invasive protocols and followed up for periods ranging from 3 to 60 months. Outcomes were assessed based on standardized clinical criteria for success and failure. Results: Lithium disilicate crowns exhibited superior long-term performance, with the majority of failures occurring in feldspathic veneers (p < 0.001), primarily due to chipping or structural fracture. Age and gender had no statistically significant influence on failure rates. Conclusions: Both feldspathic and lithium disilicate ceramic restorations represent viable treatment options for anterior dental trauma in adolescents. However, lithium disilicate demonstrates greater mechanical reliability, particularly in teeth with significant hard tissue loss. These results support the use of durable ceramic materials in adolescent restorative protocols involving dental trauma. Full article
(This article belongs to the Collection Advance in Pediatric Dentistry)
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14 pages, 2200 KiB  
Article
Tree Species as Metabolic Indicators: A Comparative Simulation in Amman, Jordan
by Anas Tuffaha and Ágnes Sallay
Land 2025, 14(8), 1566; https://doi.org/10.3390/land14081566 - 31 Jul 2025
Viewed by 345
Abstract
Urban metabolism frameworks offer insight into flows of energy, materials, and services in cities, yet tree species selection is seldom treated as a metabolic indicator. In Amman, Jordan, we integrate spatial metabolic metrics to critique monocultural greening policies and demonstrate how species choices [...] Read more.
Urban metabolism frameworks offer insight into flows of energy, materials, and services in cities, yet tree species selection is seldom treated as a metabolic indicator. In Amman, Jordan, we integrate spatial metabolic metrics to critique monocultural greening policies and demonstrate how species choices forecast long-term urban metabolic performance. Using ENVI-met 5.61 simulations, we compare Melia azedarach, Olea europaea, and Ceratonia siliqua, mainly assessing urban flow related elements like air temperature reduction, CO2 sequestration, and evapotranspiration alongside rooting depth, isoprene emissions, and biodiversity support. Melia delivers rapid cooling but shows other negatives like a low biodiversity value; Olea offers average cooling and sequestration but has allergenic pollen issues in people as a flow; Ceratonia provides scalable cooling, increased carbon uptake, and has a high ecological value. We propose a metabolic reframing of green infrastructure planning to choose urban species, guided by system feedback rather than aesthetics, to ensure long-term resilience in arid urban climates. Full article
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26 pages, 2625 KiB  
Article
Evaluating the Efficacy of the More Young HIFU Device for Facial Skin Improvement: A Comparative Study with 7D Ultrasound
by Ihab Adib and Youjun Liu
Appl. Sci. 2025, 15(15), 8485; https://doi.org/10.3390/app15158485 - 31 Jul 2025
Viewed by 472
Abstract
High-Intensity Focused Ultrasound (HIFU) is a non-invasive technology widely used in aesthetic dermatology for skin tightening and facial rejuvenation. This study aimed to evaluate the safety and efficacy of a modified HIFU device, More Young, compared to the standard 7D HIFU system through [...] Read more.
High-Intensity Focused Ultrasound (HIFU) is a non-invasive technology widely used in aesthetic dermatology for skin tightening and facial rejuvenation. This study aimed to evaluate the safety and efficacy of a modified HIFU device, More Young, compared to the standard 7D HIFU system through a randomized, single-blinded clinical trial. The More Young device features enhanced focal depth precision and energy delivery algorithms, including nine pre-programmed stabilization checkpoints to minimize treatment risks. A total of 100 participants with facial wrinkles and skin laxity were randomly assigned to receive either More Young or 7D HIFU treatment. Skin improvements were assessed at baseline and one to six months post-treatment using the VISIA® Skin Analysis System (7th Generation), focusing on eight key parameters. Patient satisfaction was evaluated through the Global Aesthetic Improvement Scale (GAIS). Data were analyzed using paired and independent t-tests, with effect sizes measured via Cohen’s d. Both groups showed significant post-treatment improvements; however, the More Young group demonstrated superior outcomes in wrinkle reduction, skin tightening, and texture enhancement, along with higher satisfaction and fewer adverse effects. No significant differences were observed in five of the eight skin parameters. Limitations include the absence of a placebo group, limited sample diversity, and short follow-up duration. Further studies are needed to validate long-term outcomes and assess performance across varied demographics and skin types. Full article
(This article belongs to the Section Biomedical Engineering)
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32 pages, 6341 KiB  
Article
Visual Culture in Architecture: Virgil Abloh’s Cross-Disciplinary Design Language
by Albert Topić, Dejan Ecet, Igor Maraš, Ivana Maraš, Miljan Janjušević and Jelena Atanacković Jeličić
Arts 2025, 14(4), 84; https://doi.org/10.3390/arts14040084 - 31 Jul 2025
Viewed by 348
Abstract
This paper investigates the integration of Virgil Abloh’s Personal Design Language (PDL) within the broader context of architectural methodology. Through a series of workshops, architecture students and professionals engaged with Abloh’s principles to examine how subtle aesthetic and functional adjustments, grounded in artistic [...] Read more.
This paper investigates the integration of Virgil Abloh’s Personal Design Language (PDL) within the broader context of architectural methodology. Through a series of workshops, architecture students and professionals engaged with Abloh’s principles to examine how subtle aesthetic and functional adjustments, grounded in artistic disciplines, can produce transformative effects on iconic 20th-century architectural forms. These workshops underscored the potential of Abloh’s interdisciplinary approach to enhance architectural discourse by introducing a novel lens through which contemporary design methodologies can be evaluated. The findings reveal that employing weighted coefficients for less commonly utilized design principles enabled novel evaluation processes, fostering creative experimentation and innovation. Additionally, this research highlights discrepancies that may arise when employing differing evaluation methodologies in the assessment of architectural work, thereby initiating a critical discussion on the public acceptance of architectural designs and the implications of varied grading frameworks in professional practice. Full article
(This article belongs to the Special Issue Art and Visual Culture—Social, Cultural and Environmental Impacts)
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14 pages, 871 KiB  
Article
Evaluation of Deviations Produced by Soft Tissue Fitting in Virtually Planned Orthognathic Surgery
by Álvaro Pérez-Sala, Pablo Montes Fernández-Micheltorena, Miriam Bobadilla, Ricardo Fernández-Valadés Gámez, Javier Martínez Goñi, Ángela Villanueva, Iñigo Calvo Archanco, José Luis Del Castillo Pardo de Vera, José Luis Cebrián Carretero, Carlos Navarro Cuéllar, Ignacio Navarro Cuellar, Gema Arenas, Ana López López, Ignacio M. Larrayoz and Rafael Peláez
Appl. Sci. 2025, 15(15), 8478; https://doi.org/10.3390/app15158478 - 30 Jul 2025
Viewed by 426
Abstract
Orthognathic surgery (OS) is a complex procedure commonly used to treat dentofacial deformities (DFDs). These conditions, related to jaw position or size and often involving malocclusion, affect approximately 15% of the population. Due to the complexity of OS, accurate planning is essential. Digital [...] Read more.
Orthognathic surgery (OS) is a complex procedure commonly used to treat dentofacial deformities (DFDs). These conditions, related to jaw position or size and often involving malocclusion, affect approximately 15% of the population. Due to the complexity of OS, accurate planning is essential. Digital assessment using computer-aided design (CAD) and computer-aided manufacturing (CAM) tools enhances surgical predictability. However, limitations in soft tissue simulation often require surgeon input to optimize aesthetic results and minimize surgical impact. This study aimed to evaluate the accuracy of virtual surgery planning (VSP) by analyzing the relationship between planning deviations and surgical satisfaction. A single-center, retrospective study was conducted on 16 patients who underwent OS at San Pedro University Hospital of La Rioja. VSP was based on CT scans using Dolphin Imaging software (v12.0, Patterson Dental, St. Paul, MN, USA) and surgeries were guided by VSP-designed occlusal splints. Outcomes were assessed using the Orthognathic Quality of Life (OQOL) questionnaire and deviations were measured through pre- and postoperative imaging. The results showed high satisfaction scores and good overall outcomes, despite moderate deviations from the virtual plan in many cases, particularly among Class II patients. A total of 63% of patients required VSP modifications due to poor soft tissue fitting, with 72% of these being Class II DFDs. Most deviations involved less maxillary advancement than planned, while maintaining optimal occlusion. This suggests that VSP may overestimate advancement needs, especially in Class II cases. No significant differences in satisfaction were observed between patients with low (<2 mm) and high (>2 mm) deviations. These findings support the use of VSP as a valuable planning tool for OS. However, surgeon experience remains essential, especially in managing soft tissue behavior. Improvements in soft tissue prediction are needed to enhance accuracy, particularly for Class II DFDs. Full article
(This article belongs to the Special Issue Intelligent Medicine and Health Care, 2nd Edition)
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16 pages, 2243 KiB  
Article
Comparative Effectiveness of Tunneling vs. Coronally Advanced Flap Techniques for Root Coverage: A 6–12-Month Randomized Clinical Trial
by Luis Chauca-Bajaña, Pedro Samuel Vásquez González, María José Alban Guijarro, Carlos Andrés Guim Martínez, Byron Velásquez Ron, Patricio Proaño Yela, Alejandro Ismael Lorenzo-Pouso, Alba Pérez-Jardón and Andrea Ordoñez Balladares
Bioengineering 2025, 12(8), 824; https://doi.org/10.3390/bioengineering12080824 - 30 Jul 2025
Viewed by 332
Abstract
Background: Gingival recession is a common condition involving apical displacement of the gingival margin, leading to root surface exposure and associated complications such as dentin hypersensitivity and root caries. Among the most effective treatment options are the tunneling technique (TUN) and the coronally [...] Read more.
Background: Gingival recession is a common condition involving apical displacement of the gingival margin, leading to root surface exposure and associated complications such as dentin hypersensitivity and root caries. Among the most effective treatment options are the tunneling technique (TUN) and the coronally advanced flap (CAF), both combined with connective tissue grafts (CTGs). This study aimed to evaluate and compare the clinical outcomes of TUN + CTG and CAF + CTG in terms of root coverage and keratinized tissue width (KTW) over a 6–12-month follow-up. Methods: A randomized, double-blind clinical trial was conducted following CONSORT guidelines (ClinicalTrials.gov ID: NCT06228534). Participants were randomly assigned to receive either TUN + CTG or CAF + CTG. Clinical parameters, including gingival recession depth (REC) and KTW, were assessed at baseline as well as 6 months and 12 months postoperatively using a calibrated periodontal probe. Statistical analysis was performed using descriptive statistics and linear mixed models to compare outcomes over time, with a significance level set at 5%. Results: Both techniques demonstrated significant clinical improvements. At 6 months, mean root coverage was 100% in CAF + CTG cases and 97% in TUN + CTG cases, while complete root coverage (REC = 0) was observed in 100% and 89% of cases, respectively. At 12 months, root coverage remained stable, at 99% in the CAF + CTG group and 97% in the TUN + CTG group. KTW increased in both groups, with higher values observed in the CAF + CTG group (3.53 mm vs. 3.11 mm in TUN + CTG at 12 months). No significant postoperative complications were reported. Conclusions: Both TUN + CTG and CAF + CTG are safe and effective techniques for treating RT1 and RT2 gingival recession, offering high percentages of root coverage and increased KTW. While CAF + CTG achieved slightly superior coverage and tissue gain, the TUN was associated with better aesthetic outcomes and faster recovery, making it a valuable alternative in clinical practice. Full article
(This article belongs to the Special Issue Biomaterials and Technology for Oral and Dental Health)
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18 pages, 2433 KiB  
Article
Effect of Preharvest Aluminum-Coated Paper Bagging on Postharvest Quality, Storability, and Browning Behavior of ‘Afrata Volou’ Quince
by Triantafyllia Georgoudaki, Persefoni Maletsika and George D. Nanos
Horticulturae 2025, 11(8), 881; https://doi.org/10.3390/horticulturae11080881 - 30 Jul 2025
Viewed by 301
Abstract
As consumer preferences tend toward safer, chemical residue-free, and nutritionally rich fruits, preharvest bagging has gained attention as a sustainable method for improving fruit quality and protecting produce from environmental and biological stressors and pesticide residues. This study assessed the impact of preharvest [...] Read more.
As consumer preferences tend toward safer, chemical residue-free, and nutritionally rich fruits, preharvest bagging has gained attention as a sustainable method for improving fruit quality and protecting produce from environmental and biological stressors and pesticide residues. This study assessed the impact of preharvest bagging using paper bags with inner aluminum coating on the physicochemical traits, storability, and browning susceptibility after cutting or bruising of ‘Afrata Volou’ quince (Cydonia oblonga Mill.) fruit grown in central Greece. Fruits were either bagged or left unbagged approximately 60 days before harvest, and evaluations were conducted at harvest and after three months of cold storage, plus two days of shelf-life. Fruit bagging reduced the quince’s flesh temperature on the tree crown. Bagging had minor effects on fruit and nutritional quality, except for more yellow skin and higher titratable acidity (TA). Also, at harvest, bagging did not significantly affect fruit flesh browning after cutting or bruising. After three months of storage, unbagged and bagged quince fruit developed more yellow skin color, without significant alterations in most quality characteristics and nutritional value, but increased total tannin content (TTC). After three months of storage, the quince flesh color determined immediately after cutting or bruising was brighter and more yellowish compared to that at harvest, due to continuation of fruit ripening, but it darkened faster with time after cutting or skin removal. Therefore, fruit bagging appears to be a sustainable practice for improving the aesthetic and some chemical quality characteristics of quince, particularly after storage, without negative impacts on other characteristics such as texture and phenolic content. Full article
(This article belongs to the Special Issue Advances in Tree Crop Cultivation and Fruit Quality Assessment)
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15 pages, 2321 KiB  
Article
Prevalence, Characteristics, and Dynamics of Mandibular Tori in a Southern German Population: A Cone Beam Computed Tomographic Analysis
by Sigmar Schnutenhaus, Julia Heim, Werner Götz and Constanze Olms
Oral 2025, 5(3), 54; https://doi.org/10.3390/oral5030054 - 29 Jul 2025
Viewed by 248
Abstract
Objectives: Torus mandibularis (TM) is a benign bony exostosis on the lingual surface of the mandible, typically developing from the third decade of life with slow progression; its etiology remains unclear. As TM excision causes no functional or aesthetic disadvantages, its use as [...] Read more.
Objectives: Torus mandibularis (TM) is a benign bony exostosis on the lingual surface of the mandible, typically developing from the third decade of life with slow progression; its etiology remains unclear. As TM excision causes no functional or aesthetic disadvantages, its use as autologous bone graft material (e.g., for pre-implant or sinus lift augmentation) has been suggested. In this study, we investigate the prevalence and expression of TM in a southern German population with regard to age and gender. Additionally, we examine whether TM undergoes dynamic changes over time, with the hypothesis that TM may show temporal growth. Material and Methods: A retrospective analysis of CBCT scans from 210 randomly selected patients (105 males, 105 females) was performed. Patients were divided into three age groups (≤40, 41–60, ≥61 years; 70 per group), and TM was measured using OsiriX MD. For the longitudinal study, 146 CBCTs from 73 patients were compared over intervals of 2–9 years. Surface changes were assessed via 3D overlay using GOM Inspect. Results: TM was found in 30.5% of patients, and its prevalence was significantly higher in males (38%) than females (23%), with no age-related differences identified. Most TMs measured <2 mm (n = 51); only five exceeded this size. No dynamic growth was observed over time. Conclusion and Clinical Implications: TM is a common anatomical variant, more frequently detected through 3D imaging than clinical examination. In most cases, size remains minimal (<2 mm), limiting its clinical use as augmentation material in rare individual cases. Full article
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17 pages, 574 KiB  
Systematic Review
Hydrogen Peroxide-Free Color Correctors for Tooth Whitening in Adolescents and Young Adults: A Systematic Review of In Vitro and Clinical Evidence
by Madalina Boruga, Gianina Tapalaga, Magda Mihaela Luca and Bogdan Andrei Bumbu
Dent. J. 2025, 13(8), 346; https://doi.org/10.3390/dj13080346 - 28 Jul 2025
Viewed by 530
Abstract
Background: The rising demand for aesthetic dental treatments has spurred interest in peroxide-free color correctors as alternatives to traditional hydrogen peroxide formulations, which are associated with tooth sensitivity and potential enamel demineralization. This systematic review evaluates the whitening efficacy and safety profile of [...] Read more.
Background: The rising demand for aesthetic dental treatments has spurred interest in peroxide-free color correctors as alternatives to traditional hydrogen peroxide formulations, which are associated with tooth sensitivity and potential enamel demineralization. This systematic review evaluates the whitening efficacy and safety profile of hydrogen peroxide-free color corrector (HPFCC) products, focusing on color change metrics, enamel and dentin integrity, and adverse effects. Methods: Following PRISMA guidelines, we searched PubMed, Scopus, and Web of Science throughout January 2025 for randomized controlled trials, observational studies, and in vitro experiments comparing HPFCC to placebo or peroxide-based agents. The data extraction covered study design, sample characteristics, intervention details, shade improvement (ΔE00 or CIE Lab), enamel/dentin mechanical properties (microhardness, roughness, elastic modulus), and incidence of sensitivity or tissue irritation. Risk of bias was assessed using the Cochrane tool for clinical studies and the QUIN tool for in vitro research. Results: Six studies (n = 20–80 samples or subjects) met the inclusion criteria. In vitro, HPFCC achieved mean ΔE00 values of 3.5 (bovine incisors; n = 80) and 2.8 (human molars; n = 20), versus up to 8.9 for carbamide peroxide (p < 0.01). Across studies, HPFCC achieved a mean ΔE00 of 2.8–3.5 surpassing the perceptibility threshold of 2.7 and approaching the clinical acceptability benchmark of 3.3. Surface microhardness increased by 12.9 ± 11.7 VHN with HPFCC (p < 0.001), and ultramicrohardness rose by 110 VHN over 56 days in prolonged use studies. No significant enamel erosion or dentin roughness changes were observed, and the sensitivity incidence remained below 3%. Conclusions: These findings derive from one clinical trial (n = 60) and five in vitro studies (n = 20–80), encompassing violet-pigment serums and gels with differing concentrations. Due to heterogeneity in designs, formulations, and outcome measures, we conducted a narrative synthesis rather than a meta-analysis. Although HPFCC ΔE00 values were lower than those of carbamide peroxide, they consistently exceeded perceptibility thresholds while maintaining enamel integrity and causing sensitivity in fewer than 3% of subjects, supporting HPFCCs as moderate but safe alternatives for young patients. Full article
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20 pages, 3386 KiB  
Article
Design of Realistic and Artistically Expressive 3D Facial Models for Film AIGC: A Cross-Modal Framework Integrating Audience Perception Evaluation
by Yihuan Tian, Xinyang Li, Zuling Cheng, Yang Huang and Tao Yu
Sensors 2025, 25(15), 4646; https://doi.org/10.3390/s25154646 - 26 Jul 2025
Viewed by 397
Abstract
The rise of virtual production has created an urgent need for both efficient and high-fidelity 3D face generation schemes for cinema and immersive media, but existing methods are often limited by lighting–geometry coupling, multi-view dependency, and insufficient artistic quality. To address this, this [...] Read more.
The rise of virtual production has created an urgent need for both efficient and high-fidelity 3D face generation schemes for cinema and immersive media, but existing methods are often limited by lighting–geometry coupling, multi-view dependency, and insufficient artistic quality. To address this, this study proposes a cross-modal 3D face generation framework based on single-view semantic masks. It utilizes Swin Transformer for multi-level feature extraction and combines with NeRF for illumination decoupled rendering. We utilize physical rendering equations to explicitly separate surface reflectance from ambient lighting to achieve robust adaptation to complex lighting variations. In addition, to address geometric errors across illumination scenes, we construct geometric a priori constraint networks by mapping 2D facial features to 3D parameter space as regular terms with the help of semantic masks. On the CelebAMask-HQ dataset, this method achieves a leading score of SSIM = 0.892 (37.6% improvement from baseline) with FID = 40.6. The generated faces excel in symmetry and detail fidelity with realism and aesthetic scores of 8/10 and 7/10, respectively, in a perceptual evaluation with 1000 viewers. By combining physical-level illumination decoupling with semantic geometry a priori, this paper establishes a quantifiable feedback mechanism between objective metrics and human aesthetic evaluation, providing a new paradigm for aesthetic quality assessment of AI-generated content. Full article
(This article belongs to the Special Issue Convolutional Neural Network Technology for 3D Imaging and Sensing)
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8 pages, 248 KiB  
Article
The Association Between Female Breast Size, Backache, and Quality of Life in Young Women: A Cross-Sectional Study
by Raphael Lotan, Natali Marmor, Sharon Weiss, Mojahed Sakhnini and Oded Hershkovich
Medicina 2025, 61(8), 1353; https://doi.org/10.3390/medicina61081353 - 26 Jul 2025
Viewed by 268
Abstract
Background and Objectives: The association between female breast size and spinal back pain is widely suggested in clinical practice but remains insufficiently quantified in general, non-surgical populations in the scientific literature. Larger breasts may increase biomechanical strain on the spine, contributing to [...] Read more.
Background and Objectives: The association between female breast size and spinal back pain is widely suggested in clinical practice but remains insufficiently quantified in general, non-surgical populations in the scientific literature. Larger breasts may increase biomechanical strain on the spine, contributing to musculoskeletal pain and reduced quality of life. This study aimed to evaluate the association between breast size and back pain in a general orthopedic population of young women. Materials and Methods: A cross-sectional study was conducted among 200 women aged 18–36 who attended orthopedic clinics for non-spinal complaints. Data were collected via structured telephone questionnaires, including demographics, self-reported breast size (cup and band), pain characteristics, and SF-12 quality of life scores. Binary logistic regression, ANOVA, and chi-square analyses assessed associations between breast size, pain presence, severity, and functional outcomes. Results: Back pain prevalence increased with breast size: only 4.9% of B cup participants reported backache, compared to 85% of DD/E cup participants. VAS scores rose from 0.3 ± 1.6 (B cup) to 6.0 ± 2.9 (DD/E cup). Each 1 cm increase in band length raised the odds of back pain by 19.8% (OR = 1.198, p < 0.001), while large cup size was associated with up to 12-fold increased odds of pain. Larger breast size was also significantly associated with work limitations and social impairment. Conclusions: Breast size was strongly associated with the presence and severity of back pain, particularly in the thoracic and cervical regions. Clinicians should consider breast size in the assessment of backache, and reduction mammaplasty may have therapeutic value beyond aesthetics. Full article
16 pages, 1023 KiB  
Article
Using Saline Water for Sustainable Floriculture: Identifying Physiological Thresholds and Floral Performance in Eight Asteraceae Species
by María Rita Guzman, Xavier Rojas-Ruilova, Catarina Gomes-Domingues and Isabel Marques
Agronomy 2025, 15(8), 1802; https://doi.org/10.3390/agronomy15081802 - 25 Jul 2025
Viewed by 295
Abstract
Water scarcity challenges floriculture, which depends on quality irrigation for ornamental value. This study assessed short-term salinity tolerance in eight Asteraceae species by measuring physiological (proline levels, antioxidant enzyme activity) and morphological (plant height, flower number, and size) responses. Plants were irrigated with [...] Read more.
Water scarcity challenges floriculture, which depends on quality irrigation for ornamental value. This study assessed short-term salinity tolerance in eight Asteraceae species by measuring physiological (proline levels, antioxidant enzyme activity) and morphological (plant height, flower number, and size) responses. Plants were irrigated with 0, 50, 100, or 300 mM NaCl for 10 days. Salinity significantly enhanced proline content and the activity of key antioxidant enzymes (catalase, peroxidase, and ascorbate peroxidase), reflecting the activation of stress defense mechanisms. However, these defenses failed to fully protect reproductive organs. Flower number and size were consistently more sensitive to salinity than vegetative traits, with significant reductions observed even at 50 mM NaCl. Responses varied between species, with Zinnia elegans and Calendula officinalis exhibiting pronounced sensitivity to salinity, whereas Tagetes patula showed relative tolerance, particularly under moderate stress conditions. The results show that flower structures are more vulnerable to ionic and osmotic disturbances than vegetative tissues, likely due to their higher metabolic demands and developmental sensitivity. Their heightened vulnerability underscores the need to prioritize reproductive performance when evaluating stress tolerance. Incorporating these traits into breeding programs is essential for developing salt-tolerant floriculture species that maintain aesthetic quality under limited water availability. Full article
(This article belongs to the Special Issue Effect of Brackish and Marginal Water on Irrigated Agriculture)
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21 pages, 12169 KiB  
Article
“Ozempic Face”: An Emerging Drug-Related Aesthetic Concern and Its Treatment with Endotissutal Bipolar Radiofrequency (RF)—Our Experience
by Luciano Catalfamo, Francesco Saverio De Ponte and Danilo De Rinaldis
J. Clin. Med. 2025, 14(15), 5269; https://doi.org/10.3390/jcm14155269 - 25 Jul 2025
Viewed by 295
Abstract
Background/Objectives: “Ozempic face” is an aesthetic side effect associated with the use of the antidiabetic agent Ozempic (semaglutide), characterized by a prematurely aged and fatigued facial appearance due to rapid weight loss. Currently, treatment options for this condition are limited. In this study, [...] Read more.
Background/Objectives: “Ozempic face” is an aesthetic side effect associated with the use of the antidiabetic agent Ozempic (semaglutide), characterized by a prematurely aged and fatigued facial appearance due to rapid weight loss. Currently, treatment options for this condition are limited. In this study, we present our clinical experience with the BodyTite device, provided by InMode Italy S.r.l. (Rome, Italy). Materials and Methods: We report a case series involving 24 patients (19 women and 5 men, aged 27–65 years), treated with subdermal bipolar radiofrequency (Endotissutal Bipolar Radiofrequency) between 2023 and 2024. All patients underwent a minimum follow-up of 12 months. At the end of the follow-up period, patients rated their satisfaction on a from 0 to 10 scale, and an independent expert assessed the stability of clinical outcomes. Results: The majority of patients reported high satisfaction levels (≥8), which correlated with the independent expert’s evaluation of treatment efficacy and result stability. The only observed adverse event was transient cutaneous erythema. Conclusions: “Ozempic face” is an increasingly common side effect associated with newer classes of antidiabetic medications. Although these drugs offer significant metabolic benefits, the accompanying facial volume loss and aging are often poorly tolerated by patients. Our findings suggest that subdermal bipolar radiofrequency represents a safe, low-risk, and cost-effective therapeutic option for the aesthetic management of Ozempic face. Full article
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38 pages, 12524 KiB  
Article
Therapeutic Efficacy of Plant-Derived Exosomes for Advanced Scar Treatment: Quantitative Analysis Using Standardized Assessment Scales
by Lidia Majewska, Agnieszka Kondraciuk, Iwona Paciepnik, Agnieszka Budzyńska and Karolina Dorosz
Pharmaceuticals 2025, 18(8), 1103; https://doi.org/10.3390/ph18081103 - 25 Jul 2025
Viewed by 583
Abstract
Background: Wound healing and scar management remain significant challenges in dermatology and aesthetic medicine. Recent advances in regenerative medicine have introduced plant-derived exosome-like nanoparticles (PDENs) as potential therapeutic agents due to their bioactive properties. This study examines the clinical application of rose [...] Read more.
Background: Wound healing and scar management remain significant challenges in dermatology and aesthetic medicine. Recent advances in regenerative medicine have introduced plant-derived exosome-like nanoparticles (PDENs) as potential therapeutic agents due to their bioactive properties. This study examines the clinical application of rose stem cell exosomes (RSCEs) in combination with established treatments for managing different types of scars. Methods: A case series of four patients with different scar etiologies (dog bite, hot oil burn, forehead trauma, and facial laser treatment complications) was treated with RSCEs in combination with microneedling (Dermapen 4.0, 0.2–0.4 mm depth) and/or thulium laser therapy (Lutronic Ultra MD, 8–14 J), or as a standalone topical treatment. All cases underwent sequential treatments over periods ranging from two to four months, with comprehensive photographic documentation of the progression. The efficacy was assessed through clinical photography and objective evaluation using the modified Vancouver Scar Scale (mVSS) and the Patient and Observer Scar Assessment Scale (POSAS), along with assessment of scar appearance, texture, and coloration. Results: All cases demonstrated progressive improvement throughout the treatment course. The dog bite scar showed significant objective improvement, with a 71% reduction in modified Vancouver Scar Scale score (from 7/13 to 2/13) and a 61% improvement in Patient and Observer Scar Assessment Scale scores after four combined treatments. The forehead trauma case exhibited similar outcomes, with a 71% improvement in mVSS score and 55–57% improvement in POSAS scores. The hot oil burn case displayed the most dramatic improvement, with a 78% reduction in mVSS score and over 70% improvement in POSAS scores, resulting in near-complete resolution without visible scarring. The facial laser complication case showed a 75% reduction in mVSS score and ~70% improvement in POSAS scores using only topical exosome application without device-based treatments. Clinical improvements across all cases included reduction in elevation, improved texture, decreased erythema, and better integration with surrounding skin. No adverse effects were reported in any of the cases. Conclusions: This preliminary case series suggests that plant-derived exosome-like nanoparticles, specifically rose stem cell exosomes (RSCEs), may enhance scar treatment outcomes when combined with microneedling and laser therapy, or even as a standalone topical treatment. The documented objective improvements, measured by standardized scar assessment scales, along with clinical enhancements in scar appearance, texture, and coloration across different scar etiologies—dog bite, burn, traumatic injury, and iatrogenic laser damage—suggest that this approach may offer a valuable addition to the current armamentarium of scar management strategies. Notably, the successful treatment of laser-induced complications using only topical exosome application demonstrates the versatility and potential of this therapeutic modality. Full article
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