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  • Article
  • Open Access
7 Citations
2,816 Views
19 Pages

Metal Ion Periplasmic-Binding Protein YfeA of Glaesserella parasuis Induces the Secretion of Pro-Inflammatory Cytokines of Macrophages via MAPK and NF-κB Signaling through TLR2 and TLR4

  • Zhen Yang,
  • Xinwei Tang,
  • Kang Wang,
  • Ke Dai,
  • Yung-Fu Chang,
  • Senyan Du,
  • Qin Zhao,
  • Xiaobo Huang,
  • Rui Wu and
  • Qigui Yan
  • + 2 authors

25 August 2022

The YfeA gene, belonging to the well-conserved ABC (ATP-binding cassette) transport system Yfe, encodes the substrate-binding subunit of the iron, zinc, and manganese transport system in bacteria. As a potential vaccine candidate in Glaesserella para...