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Search Results (3,361)

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Keywords = Wearable system

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16 pages, 5536 KiB  
Article
The Development of a Wearable-Based System for Detecting Shaken Baby Syndrome Using Machine Learning Models
by Ram Kinker Mishra, Khalid AlAnsari, Rylee Cole, Arin Nazarian, Ilkay Yildiz Potter and Ashkan Vaziri
Sensors 2025, 25(15), 4767; https://doi.org/10.3390/s25154767 - 2 Aug 2025
Viewed by 168
Abstract
Shaken Baby Syndrome (SBS) is one of the primary causes of fatal head trauma in infants and young children, occurring in about 33 per 100,000 infants annually in the U.S., with mortality rates being between 15% and 38%. Survivors frequently endure long-term disabilities, [...] Read more.
Shaken Baby Syndrome (SBS) is one of the primary causes of fatal head trauma in infants and young children, occurring in about 33 per 100,000 infants annually in the U.S., with mortality rates being between 15% and 38%. Survivors frequently endure long-term disabilities, such as cognitive deficits, visual impairments, and motor dysfunction. Diagnosing SBS remains difficult due to the lack of visible injuries and delayed symptom onset. Existing detection methods—such as neuroimaging, biomechanical modeling, and infant monitoring systems—cannot perform real-time detection and face ethical, technical, and accuracy limitations. This study proposes an inertial measurement unit (IMU)-based detection system enhanced with machine learning to identify aggressive shaking patterns. Findings indicate that wearable-based motion analysis is a promising method for recognizing high-risk shaking, offering a non-invasive, real-time solution that could minimize infant harm and support timely intervention. Full article
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45 pages, 10039 KiB  
Article
Design of an Interactive System by Combining Affective Computing Technology with Music for Stress Relief
by Chao-Ming Wang and Ching-Hsuan Lin
Electronics 2025, 14(15), 3087; https://doi.org/10.3390/electronics14153087 - 1 Aug 2025
Viewed by 276
Abstract
In response to the stress commonly experienced by young people in high-pressure daily environments, a music-based stress-relief interactive system was developed by integrating music-assisted care with emotion-sensing technology. The design principles of the system were established through a literature review on stress, music [...] Read more.
In response to the stress commonly experienced by young people in high-pressure daily environments, a music-based stress-relief interactive system was developed by integrating music-assisted care with emotion-sensing technology. The design principles of the system were established through a literature review on stress, music listening, emotion detection, and interactive devices. A prototype was created accordingly and refined through interviews with four experts and eleven users participating in a preliminary experiment. The system is grounded in a four-stage guided imagery and music framework, along with a static activity model focused on relaxation-based stress management. Emotion detection was achieved using a wearable EEG device (NeuroSky’s MindWave Mobile device) and a two-dimensional emotion model, and the emotional states were translated into visual representations using seasonal and weather metaphors. A formal experiment involving 52 users was conducted. The system was evaluated, and its effectiveness confirmed, through user interviews and questionnaire surveys, with statistical analysis conducted using SPSS 26 and AMOS 23. The findings reveal that: (1) integrating emotion sensing with music listening creates a novel and engaging interactive experience; (2) emotional states can be effectively visualized using nature-inspired metaphors, enhancing user immersion and understanding; and (3) the combination of music listening, guided imagery, and real-time emotional feedback successfully promotes emotional relaxation and increases self-awareness. Full article
(This article belongs to the Special Issue New Trends in Human-Computer Interactions for Smart Devices)
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46 pages, 4006 KiB  
Review
Solvent-Driven Electroless Nickel Coatings on Polymers: Interface Engineering, Microstructure, and Applications
by Chenyao Wang, Heng Zhai, David Lewis, Hugh Gong, Xuqing Liu and Anura Fernando
Coatings 2025, 15(8), 898; https://doi.org/10.3390/coatings15080898 (registering DOI) - 1 Aug 2025
Viewed by 273
Abstract
Electroless nickel deposition (ELD) is an autocatalytic technique extensively used to impart conductive, protective, and mechanical functionalities to inherently non-conductive synthetic substrates. This review systematically explores the fundamental mechanisms of electroless nickel deposition, emphasising recent advancements in surface activation methods, solvent systems, and [...] Read more.
Electroless nickel deposition (ELD) is an autocatalytic technique extensively used to impart conductive, protective, and mechanical functionalities to inherently non-conductive synthetic substrates. This review systematically explores the fundamental mechanisms of electroless nickel deposition, emphasising recent advancements in surface activation methods, solvent systems, and microstructural control. Critical analysis reveals that bio-inspired activation methods, such as polydopamine (PDA) and tannic acid (TA), significantly enhance coating adhesion and durability compared to traditional chemical etching and plasma treatments. Additionally, solvent engineering, particularly using polar aprotic solvents like dimethyl sulfoxide (DMSO) and ethanol-based systems, emerges as a key strategy for achieving uniform, dense, and flexible coatings, overcoming limitations associated with traditional aqueous baths. The review also highlights that microstructural tailoring, specifically the development of amorphous-nanocrystalline hybrid nickel coatings, effectively balances mechanical robustness (hardness exceeding 800 HV), flexibility, and corrosion resistance, making these coatings particularly suitable for wearable electronic textiles and smart materials. Furthermore, commercial examples demonstrate the real-world applicability and market readiness of nickel-coated synthetic fibres. Despite significant progress, persistent challenges remain, including reliable long-term adhesion, internal stress management, and environmental sustainability. Future research should prioritise environmentally benign plating baths, standardised surface activation protocols, and scalable deposition processes to fully realise the industrial potential of electroless nickel coatings. Full article
(This article belongs to the Section Surface Characterization, Deposition and Modification)
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15 pages, 2400 KiB  
Article
Robust Prediction of Cardiorespiratory Signals from a Multimodal Physiological System on the Upper Arm
by Kimberly L. Branan, Rachel Kurian, Justin P. McMurray, Madhav Erraguntla, Ricardo Gutierrez-Osuna and Gerard L. Coté
Biosensors 2025, 15(8), 493; https://doi.org/10.3390/bios15080493 - 1 Aug 2025
Viewed by 156
Abstract
Many commercial wearable sensor systems typically rely on a single continuous cardiorespiratory sensing modality, photoplethysmography (PPG), which suffers from inherent biases (i.e., differences in skin tone) and noise (e.g., motion and pressure artifacts). In this research, we present a wearable device that provides [...] Read more.
Many commercial wearable sensor systems typically rely on a single continuous cardiorespiratory sensing modality, photoplethysmography (PPG), which suffers from inherent biases (i.e., differences in skin tone) and noise (e.g., motion and pressure artifacts). In this research, we present a wearable device that provides robust estimates of cardiorespiratory variables by combining three physiological signals from the upper arm: multiwavelength PPG, single-sided electrocardiography (SS-ECG), and bioimpedance plethysmography (BioZ), along with an inertial measurement unit (IMU) providing 3-axis accelerometry and gyroscope information. We evaluated the multimodal device on 16 subjects by its ability to estimate heart rate (HR) and breathing rate (BR) in the presence of various static and dynamic noise sources (e.g., skin tone and motion). We proposed a hierarchical approach that considers the subject’s skin tone and signal quality to select the optimal sensing modality for estimating HR and BR. Our results indicate that, when estimating HR, there is a trade-off between accuracy and robustness, with SS-ECG providing the highest accuracy (low mean absolute error; MAE) but low reliability (higher rates of sensor failure), and PPG/BioZ having lower accuracy but higher reliability. When estimating BR, we find that fusing estimates from multiple modalities via ensemble bagged tree regression outperforms single-modality estimates. These results indicate that multimodal approaches to cardiorespiratory monitoring can overcome the accuracy–robustness trade-off that occurs when using single-modality approaches. Full article
(This article belongs to the Special Issue Wearable Biosensors for Health Monitoring)
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15 pages, 514 KiB  
Article
Remote Patient Monitoring Applications in Healthcare: Lessons from COVID-19 and Beyond
by Azrin Khan and Dominique Duncan
Electronics 2025, 14(15), 3084; https://doi.org/10.3390/electronics14153084 - 1 Aug 2025
Viewed by 219
Abstract
The COVID-19 pandemic catalyzed the rapid adoption of remote patient monitoring (RPM) technologies such as telemedicine and wearable devices (WDs), significantly transforming healthcare delivery. Telemedicine made virtual consultations possible, reducing in-person visits and infection risks, particularly for the management of chronic diseases. Wearable [...] Read more.
The COVID-19 pandemic catalyzed the rapid adoption of remote patient monitoring (RPM) technologies such as telemedicine and wearable devices (WDs), significantly transforming healthcare delivery. Telemedicine made virtual consultations possible, reducing in-person visits and infection risks, particularly for the management of chronic diseases. Wearable devices enabled the real-time continuous monitoring of health that assisted in condition prediction and management, such as for COVID-19. This narrative review addresses these transformations by uniquely synthesizing findings from 13 diverse studies (sourced from PubMed and Google Scholar, 2020–2024) to analyze the parallel evolution of telemedicine and WDs as interconnected RPM components. It highlights the pandemic’s dual impact, as follows: accelerating RPM innovation and adoption while simultaneously unmasking systemic challenges such as inequities in access and a need for robust integration approaches; while telemedicine usage soared during the pandemic, consumption post-pandemic, as indicated by the reviewed studies, suggests continued barriers to adoption among older adults. Likewise, wearable devices demonstrated significant potential in early disease detection and long-term health management, with promising applications extending beyond COVID-19, including long COVID conditions. Addressing the identified challenges is crucial for healthcare providers and systems to fully embrace these technologies and this would improve efficiency and patient outcomes. Full article
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36 pages, 6545 KiB  
Review
MXene-Based Composites for Energy Harvesting and Energy Storage Devices
by Jorge Alexandre Alencar Fotius and Helinando Pequeno de Oliveira
Solids 2025, 6(3), 41; https://doi.org/10.3390/solids6030041 - 1 Aug 2025
Viewed by 262
Abstract
MXenes, a class of two-dimensional transition metal carbides and nitrides, emerged as a promising material for next-generation energy storage and corresponding applications due to their unique combination of high electrical conductivity, tunable surface chemistry, and lamellar structure. This review highlights recent advances in [...] Read more.
MXenes, a class of two-dimensional transition metal carbides and nitrides, emerged as a promising material for next-generation energy storage and corresponding applications due to their unique combination of high electrical conductivity, tunable surface chemistry, and lamellar structure. This review highlights recent advances in MXene-based composites, focusing on their integration into electrode architectures for the development of supercapacitors, batteries, and multifunctional devices, including triboelectric nanogenerators. It serves as a comprehensive overview of the multifunctional capabilities of MXene-based composites and their role in advancing efficient, flexible, and sustainable energy and sensing technologies, outlining how MXene-based systems are poised to redefine multifunctional energy platforms. Electrochemical performance optimization strategies are discussed by considering surface functionalization, interlayer engineering, scalable synthesis techniques, and integration with advanced electrolytes, with particular attention paid to the development of hybrid supercapacitors, triboelectric nanogenerators (TENGs), and wearable sensors. These applications are favored due to improved charge storage capability, mechanical properties, and the multifunctionality of MXenes. Despite these aspects, challenges related to long-term stability, sustainable large-scale production, and environmental degradation must still be addressed. Emerging approaches such as three-dimensional self-assembly and artificial intelligence-assisted design are identified as key challenges for overcoming these issues. Full article
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24 pages, 1835 KiB  
Review
Multidomain Molecular Sensor Devices, Systems, and Algorithms for Improved Physiological Monitoring
by Lianna D. Soriano, Shao-Xiang Go, Lunna Li, Natasa Bajalovic and Desmond K. Loke
Micromachines 2025, 16(8), 900; https://doi.org/10.3390/mi16080900 (registering DOI) - 31 Jul 2025
Viewed by 95
Abstract
Molecular sensor systems, e.g., implantables and wearables, provide extensive health-related monitoring. Glucose sensor systems have historically prevailed in wearable bioanalysis applications due to their continuous and reliable glucose monitoring, a feat not yet accomplished for other biomarkers. However, the advancement of reagentless detection [...] Read more.
Molecular sensor systems, e.g., implantables and wearables, provide extensive health-related monitoring. Glucose sensor systems have historically prevailed in wearable bioanalysis applications due to their continuous and reliable glucose monitoring, a feat not yet accomplished for other biomarkers. However, the advancement of reagentless detection methodologies may facilitate the creation of molecular sensor systems for multiple analytes. Improving the sensitivity and selectivity of molecular sensor systems is also crucial for biomarker detection under intricate physiological circumstances. The term multidomain molecular sensor systems is utilized to refer, in general, to both biological and chemical sensor systems. This review examines methodologies for enhancing signal amplification, improving selectivity, and facilitating reagentless detection in multidomain molecular sensor devices. The review also analyzes the fundamental components of multidomain molecular sensor systems, including substrate materials, bodily fluids, power, and decision-making units. The review article further investigates how extensive data gathered from multidomain molecular sensor systems, in conjunction with current data processing algorithms, facilitate biomarker detection for precision medicine. Full article
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24 pages, 624 KiB  
Systematic Review
Integrating Artificial Intelligence into Perinatal Care Pathways: A Scoping Review of Reviews of Applications, Outcomes, and Equity
by Rabie Adel El Arab, Omayma Abdulaziz Al Moosa, Zahraa Albahrani, Israa Alkhalil, Joel Somerville and Fuad Abuadas
Nurs. Rep. 2025, 15(8), 281; https://doi.org/10.3390/nursrep15080281 - 31 Jul 2025
Viewed by 126
Abstract
Background: Artificial intelligence (AI) and machine learning (ML) have been reshaping maternal, fetal, neonatal, and reproductive healthcare by enhancing risk prediction, diagnostic accuracy, and operational efficiency across the perinatal continuum. However, no comprehensive synthesis has yet been published. Objective: To conduct a scoping [...] Read more.
Background: Artificial intelligence (AI) and machine learning (ML) have been reshaping maternal, fetal, neonatal, and reproductive healthcare by enhancing risk prediction, diagnostic accuracy, and operational efficiency across the perinatal continuum. However, no comprehensive synthesis has yet been published. Objective: To conduct a scoping review of reviews of AI/ML applications spanning reproductive, prenatal, postpartum, neonatal, and early child-development care. Methods: We searched PubMed, Embase, the Cochrane Library, Web of Science, and Scopus through April 2025. Two reviewers independently screened records, extracted data, and assessed methodological quality using AMSTAR 2 for systematic reviews, ROBIS for bias assessment, SANRA for narrative reviews, and JBI guidance for scoping reviews. Results: Thirty-nine reviews met our inclusion criteria. In preconception and fertility treatment, convolutional neural network-based platforms can identify viable embryos and key sperm parameters with over 90 percent accuracy, and machine-learning models can personalize follicle-stimulating hormone regimens to boost mature oocyte yield while reducing overall medication use. Digital sexual-health chatbots have enhanced patient education, pre-exposure prophylaxis adherence, and safer sexual behaviors, although data-privacy safeguards and bias mitigation remain priorities. During pregnancy, advanced deep-learning models can segment fetal anatomy on ultrasound images with more than 90 percent overlap compared to expert annotations and can detect anomalies with sensitivity exceeding 93 percent. Predictive biometric tools can estimate gestational age within one week with accuracy and fetal weight within approximately 190 g. In the postpartum period, AI-driven decision-support systems and conversational agents can facilitate early screening for depression and can guide follow-up care. Wearable sensors enable remote monitoring of maternal blood pressure and heart rate to support timely clinical intervention. Within neonatal care, the Heart Rate Observation (HeRO) system has reduced mortality among very low-birth-weight infants by roughly 20 percent, and additional AI models can predict neonatal sepsis, retinopathy of prematurity, and necrotizing enterocolitis with area-under-the-curve values above 0.80. From an operational standpoint, automated ultrasound workflows deliver biometric measurements at about 14 milliseconds per frame, and dynamic scheduling in IVF laboratories lowers staff workload and per-cycle costs. Home-monitoring platforms for pregnant women are associated with 7–11 percent reductions in maternal mortality and preeclampsia incidence. Despite these advances, most evidence derives from retrospective, single-center studies with limited external validation. Low-resource settings, especially in Sub-Saharan Africa, remain under-represented, and few AI solutions are fully embedded in electronic health records. Conclusions: AI holds transformative promise for perinatal care but will require prospective multicenter validation, equity-centered design, robust governance, transparent fairness audits, and seamless electronic health record integration to translate these innovations into routine practice and improve maternal and neonatal outcomes. Full article
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36 pages, 2671 KiB  
Article
DIKWP-Driven Artificial Consciousness for IoT-Enabled Smart Healthcare Systems
by Yucong Duan and Zhendong Guo
Appl. Sci. 2025, 15(15), 8508; https://doi.org/10.3390/app15158508 (registering DOI) - 31 Jul 2025
Viewed by 181
Abstract
This study presents a DIKWP-driven artificial consciousness framework for IoT-enabled smart healthcare, integrating a Data–Information–Knowledge–Wisdom–Purpose (DIKWP) cognitive architecture with a software-defined IoT infrastructure. The proposed system deploys DIKWP agents at edge and cloud nodes to transform raw sensor data into high-level knowledge and [...] Read more.
This study presents a DIKWP-driven artificial consciousness framework for IoT-enabled smart healthcare, integrating a Data–Information–Knowledge–Wisdom–Purpose (DIKWP) cognitive architecture with a software-defined IoT infrastructure. The proposed system deploys DIKWP agents at edge and cloud nodes to transform raw sensor data into high-level knowledge and purpose-driven actions. This is achieved through a structured DIKWP pipeline—from data acquisition and information processing to knowledge extraction, wisdom inference, and purpose-driven decision-making—that enables semantic reasoning, adaptive goal-driven responses, and privacy-preserving decision-making in healthcare environments. The architecture integrates wearable sensors, edge computing nodes, and cloud services to enable dynamic task orchestration and secure data fusion. For evaluation, a smart healthcare scenario for early anomaly detection (e.g., arrhythmia and fever) was implemented using wearable devices with coordinated edge–cloud analytics. Simulated experiments on synthetic vital sign datasets achieved approximately 98% anomaly detection accuracy and up to 90% reduction in communication overhead compared to cloud-centric solutions. Results also demonstrate enhanced explainability via traceable decisions across DIKWP layers and robust performance under intermittent connectivity. These findings indicate that the DIKWP-driven approach can significantly advance IoT-based healthcare by providing secure, explainable, and adaptive services aligned with clinical objectives and patient-centric care. Full article
(This article belongs to the Special Issue IoT in Smart Cities and Homes, 2nd Edition)
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3 pages, 131 KiB  
Editorial
Advances in Human–Machine Systems, Human–Machine Interfaces and Human Wearable Device Performance
by Kai Way Li and Lu Peng
Appl. Sci. 2025, 15(15), 8490; https://doi.org/10.3390/app15158490 (registering DOI) - 31 Jul 2025
Viewed by 101
Abstract
The human–machine system (HMS) and human–machine interface (HMI) are among the top factors that affect the development of advanced systems, equipment, and products [...] Full article
15 pages, 3532 KiB  
Article
Improving Motion Estimation Accuracy in Underdetermined Problems Using Physics-Informed Neural Networks with Inverse Kinematics and a Digital Human Model
by Yuya Hishikawa, Takashi Kusaka, Yoshifumi Tanaka, Yukiyasu Domae, Naoki Shirakura, Natsuki Yamanobe, Yui Endo, Mitsunori Tada, Natsuki Miyata and Takayuki Tanaka
Electronics 2025, 14(15), 3055; https://doi.org/10.3390/electronics14153055 - 30 Jul 2025
Viewed by 153
Abstract
With the rapid technological advancements in wearable devices, motion and health management have significantly improved, enabling the measurement of various biometric data with compact equipment. Our research focuses on motion measurement but, in general, full-body motion estimation requires motion capture systems or multiple [...] Read more.
With the rapid technological advancements in wearable devices, motion and health management have significantly improved, enabling the measurement of various biometric data with compact equipment. Our research focuses on motion measurement but, in general, full-body motion estimation requires motion capture systems or multiple inertial sensors, making it necessary to directly measure movement itself. In this study, we propose estimating full-body posture using inverse kinematics based on trunk posture and limb-end information collected through wearable devices. To enhance estimation accuracy in this underdetermined problem, we employ Physics-Informed Neural Networks (PINNs), which efficiently learn using physical laws as a loss function, along with a high-precision inverse kinematics model of a digital human. Through this approach, we enable high-accuracy full-body posture estimation even with wearable devices in underdetermined scenarios. Full article
(This article belongs to the Special Issue New Advances in Machine Learning and Its Applications)
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25 pages, 8468 KiB  
Article
An Autonomous Localization Vest System Based on Advanced Adaptive PDR with Binocular Vision Assistance
by Tianqi Tian, Yanzhu Hu, Xinghao Zhao, Hui Zhao, Yingjian Wang and Zhen Liang
Micromachines 2025, 16(8), 890; https://doi.org/10.3390/mi16080890 (registering DOI) - 30 Jul 2025
Viewed by 135
Abstract
Despite significant advancements in indoor navigation technology over recent decades, it still faces challenges due to excessive dependency on external infrastructure and unreliable positioning in complex environments. This paper proposes an autonomous localization system that integrates advanced adaptive pedestrian dead reckoning (APDR) and [...] Read more.
Despite significant advancements in indoor navigation technology over recent decades, it still faces challenges due to excessive dependency on external infrastructure and unreliable positioning in complex environments. This paper proposes an autonomous localization system that integrates advanced adaptive pedestrian dead reckoning (APDR) and binocular vision, designed to provide a low-cost, high-reliability, and high-precision solution for rescuers. By analyzing the characteristics of measurement data from various body parts, the chest is identified as the optimal placement for sensors. A chest-mounted advanced APDR method based on dynamic step segmentation detection and adaptive step length estimation has been developed. Furthermore, step length features are innovatively integrated into the visual tracking algorithm to constrain errors. Visual data is fused with dead reckoning data through an extended Kalman filter (EKF), which notably enhances the reliability and accuracy of the positioning system. A wearable autonomous localization vest system was designed and tested in indoor corridors, underground parking lots, and tunnel environments. Results show that the system decreases the average positioning error by 45.14% and endpoint error by 38.6% when compared to visual–inertial odometry (VIO). This low-cost, wearable solution effectively meets the autonomous positioning needs of rescuers in disaster scenarios. Full article
(This article belongs to the Special Issue Artificial Intelligence for Micro Inertial Sensors)
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40 pages, 3463 KiB  
Review
Machine Learning-Powered Smart Healthcare Systems in the Era of Big Data: Applications, Diagnostic Insights, Challenges, and Ethical Implications
by Sita Rani, Raman Kumar, B. S. Panda, Rajender Kumar, Nafaa Farhan Muften, Mayada Ahmed Abass and Jasmina Lozanović
Diagnostics 2025, 15(15), 1914; https://doi.org/10.3390/diagnostics15151914 - 30 Jul 2025
Viewed by 466
Abstract
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, [...] Read more.
Healthcare data rapidly increases, and patients seek customized, effective healthcare services. Big data and machine learning (ML) enabled smart healthcare systems hold revolutionary potential. Unlike previous reviews that separately address AI or big data, this work synthesizes their convergence through real-world case studies, cross-domain ML applications, and a critical discussion on ethical integration in smart diagnostics. The review focuses on the role of big data analysis and ML towards better diagnosis, improved efficiency of operations, and individualized care for patients. It explores the principal challenges of data heterogeneity, privacy, computational complexity, and advanced methods such as federated learning (FL) and edge computing. Applications in real-world settings, such as disease prediction, medical imaging, drug discovery, and remote monitoring, illustrate how ML methods, such as deep learning (DL) and natural language processing (NLP), enhance clinical decision-making. A comparison of ML models highlights their value in dealing with large and heterogeneous healthcare datasets. In addition, the use of nascent technologies such as wearables and Internet of Medical Things (IoMT) is examined for their role in supporting real-time data-driven delivery of healthcare. The paper emphasizes the pragmatic application of intelligent systems by highlighting case studies that reflect up to 95% diagnostic accuracy and cost savings. The review ends with future directions that seek to develop scalable, ethical, and interpretable AI-powered healthcare systems. It bridges the gap between ML algorithms and smart diagnostics, offering critical perspectives for clinicians, data scientists, and policymakers. Full article
(This article belongs to the Special Issue Machine-Learning-Based Disease Diagnosis and Prediction)
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21 pages, 3471 KiB  
Review
Nanomedicine: The Effective Role of Nanomaterials in Healthcare from Diagnosis to Therapy
by Raisa Nazir Ahmed Kazi, Ibrahim W. Hasani, Doaa S. R. Khafaga, Samer Kabba, Mohd Farhan, Mohammad Aatif, Ghazala Muteeb and Yosri A. Fahim
Pharmaceutics 2025, 17(8), 987; https://doi.org/10.3390/pharmaceutics17080987 - 30 Jul 2025
Viewed by 200
Abstract
Nanotechnology is revolutionizing medicine by enabling highly precise diagnostics, targeted therapies, and personalized healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control. Engineered nanoparticles (NPs), such as liposomes, polymeric carriers, and carbon-based [...] Read more.
Nanotechnology is revolutionizing medicine by enabling highly precise diagnostics, targeted therapies, and personalized healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control. Engineered nanoparticles (NPs), such as liposomes, polymeric carriers, and carbon-based nanomaterials, enhance drug solubility, protect therapeutic agents from degradation, and enable site-specific delivery, thereby reducing toxicity to healthy tissues. In diagnostics, nanosensors and contrast agents provide ultra-sensitive detection of biomarkers, supporting early diagnosis and real-time monitoring. Nanotechnology also contributes to regenerative medicine, antimicrobial therapies, wearable devices, and theranostics, which integrate treatment and diagnosis into unified systems. Advanced innovations such as nanobots and smart nanosystems further extend these capabilities, enabling responsive drug delivery and minimally invasive interventions. Despite its immense potential, nanomedicine faces challenges, including biocompatibility, environmental safety, manufacturing scalability, and regulatory oversight. Addressing these issues is essential for clinical translation and public acceptance. In summary, nanotechnology offers transformative tools that are reshaping medical diagnostics, therapeutics, and disease prevention. Through continued research and interdisciplinary collaboration, it holds the potential to significantly enhance treatment outcomes, reduce healthcare costs, and usher in a new era of precise and personalized medicine. Full article
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18 pages, 4452 KiB  
Article
Upper Limb Joint Angle Estimation Using a Reduced Number of IMU Sensors and Recurrent Neural Networks
by Kevin Niño-Tejada, Laura Saldaña-Aristizábal, Jhonathan L. Rivas-Caicedo and Juan F. Patarroyo-Montenegro
Electronics 2025, 14(15), 3039; https://doi.org/10.3390/electronics14153039 - 30 Jul 2025
Viewed by 264
Abstract
Accurate estimation of upper-limb joint angles is essential in biomechanics, rehabilitation, and wearable robotics. While inertial measurement units (IMUs) offer portability and flexibility, systems requiring multiple inertial sensors can be intrusive and complex to deploy. In contrast, optical motion capture (MoCap) systems provide [...] Read more.
Accurate estimation of upper-limb joint angles is essential in biomechanics, rehabilitation, and wearable robotics. While inertial measurement units (IMUs) offer portability and flexibility, systems requiring multiple inertial sensors can be intrusive and complex to deploy. In contrast, optical motion capture (MoCap) systems provide precise tracking but are constrained to controlled laboratory environments. This study presents a deep learning-based approach for estimating shoulder and elbow joint angles using only three IMU sensors positioned on the chest and both wrists, validated against reference angles obtained from a MoCap system. The input data includes Euler angles, accelerometer, and gyroscope data, synchronized and segmented into sliding windows. Two recurrent neural network architectures, Convolutional Neural Network with Long-short Term Memory (CNN-LSTM) and Bidirectional LSTM (BLSTM), were trained and evaluated using identical conditions. The CNN component enabled the LSTM to extract spatial features that enhance sequential pattern learning, improving angle reconstruction. Both models achieved accurate estimation performance: CNN-LSTM yielded lower Mean Absolute Error (MAE) in smooth trajectories, while BLSTM provided smoother predictions but underestimated some peak movements, especially in the primary axes of rotation. These findings support the development of scalable, deep learning-based wearable systems and contribute to future applications in clinical assessment, sports performance analysis, and human motion research. Full article
(This article belongs to the Special Issue Wearable Sensors for Human Position, Attitude and Motion Tracking)
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