Search Results (909)

Objective: Seaweed and microalgae provide antioxidants, polyunsaturated fatty acids, and bioactive compounds that may enhance exercise performance and accelerate recovery. However, evidence remains inconsistent. This systematic review and meta-analysis aimed to evaluate the effects of algae-derived supplementation on exercise performance and physiological recovery outcomes in healthy and athletic adults. Methods: This review was registered in PROSPERO (CRD420251166723) and conducted in accordance with PRISMA 2020 guidelines. PubMed, Web of Science, Embase, Cochrane Library, EBSCO, and CNKI were systematically searched for randomized controlled trials (RCTs) evaluating algae supplementation in exercise contexts. Inclusion and exclusion criteria were defined based on the PICOS framework. Primary outcomes included VO₂max, Time to exhaustion (TTE), maximal power output (WRmax), Time-Trial (TT) performance, and creatine kinase (CK). Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Subgroup, sensitivity, and publication bias analyses were performed. Results: Twenty-two RCTs (n = 822) investigating Spirulina, Chlorella, brown-algal polysaccharides, or astaxanthin met inclusion criteria. Algae supplementation showed a suggestive improvement in VO₂max (SMD = 0.88, 95%CI: 0.00–1.75) and significantly improved in TTE (SMD = 1.06, 95%CI: 0.16–1.96), with smaller effects on WRmax (SMD = 0.29, 95%CI: 0.03–0.55), and no significant benefit for TT performance (SMD = −0.27, 95%CI: −0.74 to 0.21). Regarding recovery, CK concentrations were significantly reduced (SMD = −0.78, 95%CI: −1.28 to −0.28). Subgroup analysis suggested greater effects for Chlorella supplementation, higher dosages, and aerobic training contexts; reductions in muscle-damage markers were more evident following resistance exercise. Sensitivity analyses supported the robustness of the main findings with minimal evidence of publication bias. Conclusions: Algae-derived supplements—particularly Spirulina and Chlorella—may modestly enhance aerobic exercise performance and attenuate exercise-induced muscle damage under certain conditions. Effects appear to depend on algae species, dosing strategies, intervention duration, and training modality. High-quality, multi-center RCTs incorporating mechanistic endpoints are needed to clarify optimal application and to develop athlete-specific recommendations. Full article

Basketball performance is influenced by cardiorespiratory fitness and body composition. However, evidence regarding the ability of maximal oxygen uptake (VO₂max) to distinguish between competitive levels remains inconsistent. This study aimed to examine differences in cardiorespiratory fitness and body composition between professional and amateur basketball players and to explore their contribution to variability in relative VO₂max. This pilot study also informed sample size estimation for future studies. A cross-sectional study was conducted with 12 professional (21.0 ± 2.3 years; BMI: 25.37 ± 3.04 kg/m²) and 12 amateur (22.6 ± 1.7 years; BMI: 26.83 ± 3.24 kg/m²) male basketball players. Absolute and relative VO₂max, ventilatory thresholds, and body composition (five-component fractionation) were assessed. Between-group comparisons were performed using Welch’s t-tests, effect sizes were estimated using Hedges’ g, and covariance analyses were adjusted for height and body fat percentage. No statistically significant differences were observed in relative VO₂max between groups. However, the absolute second ventilatory threshold was significantly higher in professional players, and absolute VO₂max showed a large effect size favoring this group. Professionals also showed lower body fat percentage and greater fat-free mass (p < 0.01; g ≈ 1.2). These findings suggest that body composition differences may partly explain variability in relative VO₂max between competitive levels. Full article

Background: Vitamin D deficiency has been implicated in disturbances of glucose and lipid metabolism, particularly in occupational groups with limited sunlight exposure. This study aimed to examine the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and markers of carbohydrate and lipid metabolism in salt mine workers. Methods: This cross-sectional study involved 62 male salt miners (aged 25–63 years), stratified by work depth (surface, ≤750 m, and >750 m). Anthropometric characteristics, body composition, cardiorespiratory fitness (VO_2max), and biochemical parameters were assessed. Blood analyses included fasting glucose, insulin, lipid profile, TSH, and 25(OH)D. Insulin resistance was evaluated via the HOMA-IR index. Results: The cohort exhibited a high prevalence of overweight and obesity (mean BMI > 28 kg/m²). Significant differences in VO_2max were observed between groups (p < 0.05). Elevated fasting glucose (>100 mg/dL) was observed in 47% of participants, and 22% presented HOMA-IR values > 2.5. In the regression model, vitamin D supplementation was the strongest predictor of 25(OH)D levels, explaining 25.5% of its variance. The addition of HDL cholesterol increased the explained variance to 35.6%, whereas HOMA-IR contributed an additional 3.9% (p = 0.094). Conclusions: In salt miners, insufficient vitamin D status coexists with excess adiposity and impaired glucose homeostasis. Serum 25(OH)D was more strongly associated with supplementation and HDL-C than with HOMA-IR. These findings suggest that monitoring vitamin D status is relevant in the occupational health evaluation of this group. Full article

Background/Objectives: Masters athletes are adults aged ≥40 who compete in sport, exhibiting superior physical function and healthier aging than their sedentary peers. However, even highly trained masters athletes experience age-related performance declines. Women masters athletes represent a growing yet understudied population who may face unique physiological challenges. This scoping review synthesizes literature from 1984 to 2024, examining the impact of age and menopause on determinants of endurance performance in women masters athletes. Methods: Following JBI scoping review methodology, six databases were searched (Medline, Embase, Central, CINAHL, SPORTdiscus, Scopus). Studies were evaluated for population characteristics, methodological approaches, and physiological determinants of performance (i.e., aerobic capacity, lactate kinetics, and exercise economy). Results: Twenty-nine studies were included. Most (n = 28) assessed aerobic capacity, reporting declines between 0.36 and 0.84 mL·kg⁻¹·min⁻¹·year⁻¹ (0.5–2.4%·year⁻¹). These reductions were primarily associated with decreased cardiac output followed by changes in body composition. Training volume emerged as a predictor of aerobic capacity, but the effects of menopause were unclear. Findings on lactate kinetics and exercise economy were mixed but preliminary research indicated that lactate threshold relative to VO₂max generally increased, peak lactate remained stable and energy cost increased with age. Fitness and health characteristics among women athletes differed from sedentary populations, emphasizing the need for athlete-specific data to support training and health decisions. Conclusions: Aging is associated with decreased aerobic capacity and variable changes in lactate kinetics and exercise economy. While training volume may attenuate performance decrements, the impact of menopause remains uncertain, underscoring the need for longitudinal research to better support this growing segment of the population. Full article

Background/Objectives: To develop and internally validate multiple linear regression models to predict estimated VO2max from anthropometric variables and easily obtainable physical fitness tests in active university students and to compare model performance when estimated VO2max was derived from the Rockport Walk Test versus the 20-m Shuttle Run (Course Navette). Methods: Anthropometric variables and physical fitness indicators, including body mass index (BMI), Ruffier index, and burpee repetitions, as well as sex and age, were evaluated. Estimated VO2max was obtained separately from the Rockport Walk Test and the 20-m Shuttle Run using their respective field test equations. For each test, a multiple linear regression model was fitted using the same set of predictors. Model performance was assessed using apparent metrics and internal validation with optimism correction based on repeated cross-validation. Results: The Rockport walk test model showed better predictive performance, explaining 55.2% of the variability in estimated VO2max (R² = 0.552; adjusted R² = 0.498) with a lower prediction error (RMSE = 3.54 mL·kg⁻¹·min⁻¹). In contrast, the 20-m shuttle run model showed lower explanatory capacity (R² = 0.319; adjusted R² = 0.256) and a substantially higher prediction error (RMSE = 11.93 mL·kg⁻¹·min⁻¹). Internal validation reduced performance in both models, more markedly in the 20-m shuttle run, where the corrected R² fell to 0.163 and the corrected RMSE increased to 13.18 mL·kg⁻¹·min⁻¹, compared with 0.338 and 4.37 mL·kg⁻¹·min⁻¹ in the Rockport walk test. Conclusions: Estimated VO2max can be predicted pragmatically using low-cost models based on simple variables in a university setting; however, model performance depends on the field test used. The Rockport walk test appears more suitable for prediction using general-purpose predictors, whereas the 20-m shuttle run may require more test-specific predictors and external validation before application beyond the development sample. Full article

Obesity is a chronic disease characterized by excessive fat accumulation. Irisin, released during exercise, regulates energy metabolism and may contribute to exercise-induced metabolic adaptations. This study aimed to compare the effects of 24 weeks of two different training programs on body composition, physical capacities, and irisin levels in male adults with obesity, and to investigate the relationship between irisin and metabolic parameters. Thirteen male adults with obesity were randomly assigned to polarized (POL) or threshold (THR) training programs. Anthropometric measurements, physical capacity parameters, serum and salivary samples were collected before (T0) and after the training period (T1). Irisin levels were measured by ELISA. After training, body composition significantly improved, with reductions in body mass and body mass index, and an increase in fat-free mass. Maximal oxygen consumption (V’O₂max) significantly increased, while a decrease in HRmax indicated improved cardiac efficiency. Although serum and salivary irisin levels did not significantly increase overall, a trend toward increased irisin was observed in the THR group. Furthermore, serum irisin at T1 positively correlated with V’O₂ at the respiratory compensation point (p = 0.019), and V’O₂max (p = 0.031). Both POL and THR training programs significantly improved body composition and cardiometabolic fitness after 24 weeks. The positive association of irisin with aerobic fitness parameters suggests that irisin may reflect physiological adaptations to exercise. Full article

Air pollution is one of the major environmental challenges threatening global sustainable development and human health. The World Health Organization identifies it as a critical factor contributing to non-communicable diseases and inequality, especially in vulnerable populations such as children. The findings highlight the negative effects of environmental degradation on physical health and underline the urgent need to incorporate health metrics, such as children’s fitness, into sustainability monitoring frameworks and public policies aiming at cleaner and healthier urban environments. The aim of this study was to examine the association between ambient particulate pollution and cardiorespiratory fitness in school-aged children from two rural villages in southern Spain characterised by relatively higher and lower levels of particulate matter. A total of 938 children (primary and secondary school levels) participated in a naturalistic pre–post study design. Cardiorespiratory fitness was assessed using the 6 min walk test, where maximal oxygen uptake (VO₂max) was estimated. Assessments were conducted before and after a period characterised by unfavourable air-quality conditions in the higher-pollution village. The students were assigned by convenience into an experimental [n = 476 (EG)] and a control group [n = 462 (CG)]. The t-test, repeated measures analysis and MANOVA test were used in order to report differences within and between groups, as well as time-points and academic levels. The significance level was set at p < 0.05. Significant differences between groups were reported within the pre-test period, showing elevated pre-test values in the CG compared to the EG. The EG showed a higher pre–post difference in estimated VO₂max compared to the CG for primary education level (16.19%, ES(d) = 0.91 vs. 3.07%, ES(d) = 0.26; p < 0.001, respectively); secondary education (EG: 12.29%, ES = 0.91 vs. CG: 1.69, ES(d) = 0.16); and the whole population (EG: 14.72%, ES = 0.91 vs. CG: 2.84, ES = 0.25). It seems that the environmental context, and specifically the air pollution in the area of residence, may be an important factor to consider in relation to the assessment of physical fitness in the school-aged youth population. Full article

Background: The Global Positioning System (GPS) and wearable monitoring technologies are increasingly applied in sport science to quantify training load; however, data from female cross-country skiers in nations with emerging competitive programs remain scarce. This case series covering the complete national team roster analyzed the complete annual training cycle of the Korean women’s national cross-country skiing team (KCF) using GPS and heart rate-based wearable sensors. Methods: All three national team members were monitored throughout the 2022–2023 season (52 weeks), structured into General Preparation Period 1 (April–July), General Preparation Period 2 (August–November), and Competition Period (December–March). Individualized five-zone intensity thresholds were established through graded exercise testing on a roller ski treadmill with ventilatory threshold and blood lactate determination, independently assessed by two exercise physiologists (PhD level). Results: The total annual training volume was 667.72 h, comprising roller/on-snow skiing (54.0%), running (23.3%), and strength training (22.7%). The endurance-only intensity distribution demonstrated a polarized pattern (Zones 1–2: 91.5%). The total annual training distance reached 4673.30 km. The mean FIS points were 108.46 ± 38.60, and the mean VO₂max was 60.17 ± 6.11 mL·kg⁻¹·min⁻¹. Conclusions: When benchmarked against world-class female (WCF) standards (800–950 h annually), the overall training volume was approximately 18–30% lower. The relative strength training allocation (22.7%) exceeded typical WCF values (10–15%). These observations should be interpreted cautiously given the small sample size and cross-study comparison design, using published literature-based benchmarks. Full article

This study aimed to identify distinct lactate kinetic phenotypes in professional soccer players using unsupervised machine learning and determine their relationship with maximal running velocity (V_max) through explainable artificial intelligence methods. A total of 361 professional male soccer players from the First Division participated in the study. Incremental treadmill tests measured lactate concentrations at five standardized velocities, alongside VO_2max, V_max, lactate threshold (LT), and anaerobic threshold (AT) parameters. Three distinct lactate kinetic phenotypes emerged: Economical Aerobic (n = 216), Balanced Metabolic (n = 19), and High Producer (n = 126). The Economical Aerobic phenotype demonstrated superior performance metrics compared to High Producer (V_max: 15.85 ± 0.85 km/h; VO_2max: 56.20 ± 4.26 mL/kg/min; p < 0.001). Initial multicollinearity assessment revealed notable collinearity among all 10 candidate predictors (VIF > 10; maximum VIF = 10.75 for V_AT), necessitating rigorous feature selection. Ridge regression with 4 selected features (V_AT, VO_2max, 9.5 km/h lactate, 14 km/h lactate) achieved moderate but statistically significant predictive performance: 10-fold cross-validation R²= 0.392 ± 0.147 (permutation test p = 0.001). Standardized coefficients identified V_AT (β = 0.399) as the dominant predictor, followed by VO_2max (β = 0.253), 9.5 km/h lactate (β = 0.107), and 14 km/h lactate (β = −0.066). Lactate kinetic phenotyping reveals position-independent metabolic profiles with potentially meaningful performance associations in professional soccer. The Economical Aerobic phenotype demonstrates performance advantages associated with superior anaerobic threshold capacity. These exploratory findings suggest that individualized training strategies based on metabolic phenotype rather than playing position alone warrant further investigation, with potential applications for talent identification, training periodization, and return-to-play protocols pending prospective validation. Full article

Background: The impact of cigarette smoking on cardiopulmonary function in elite athletes remains poorly characterised. This study aimed to evaluate the prevalence of smoking and its effects on pulmonary and exercise performance parameters among top-level competitors across different sport disciplines. Methods: 1005 Olympic-level athletes participating underwent comprehensive pre-participation screening, including spirometry and cardiopulmonary exercise testing (CPET). Smoking status was determined according to WHO definitions. Results: Among the 1005 athletes (53.4% males; mean age 26 ± 8.8 years), 117 (11.6%) were current smokers, predominantly males (70.9%). No smokers were identified among endurance athletes. Compared to non-smokers (n = 679), smokers were older (28 ± 5.8 vs. 25.5 ± 10.4 years, p = 0.026) and more frequently involved in mixed and skill disciplines (p = 0.043 and p = 0.006, respectively). In male smokers, spirometry revealed lower FVC (97.2 ± 10.3% vs. 101.1 ± 11.7%, p = 0.006), FEV₁ (97.3 ± 12.4% vs. 101.4 ± 10.3%, p = 0.002), and MVV (p = 0.010). CPET showed reduced functional capacity (W/kg, p < 0.0001), lower VO₂max (38.5 ± 7.8 vs. 42.2 ± 6.8 mL/min/kg, p < 0.0001), decreased O₂ pulse (p = 0.007) and lower first and second ventilatory thresholds (respectively p = 0.025; and p = 0.004), Similar but less pronounced reductions in VO₂max were found in female smokers (p = 0.003). Conclusions: Chronic smoking is associated with early spirometric and ventilatory impairments in elite athletes associated with lower aerobic capacity, despite their high levels of fitness. These effects are more marked in males, while females may exhibit partial protection. These findings highlight the importance of integrating smoking cessation and respiratory monitoring into athlete health programs. Full article

High-intensity interval training (HIIT) is widely used to enhance aerobic performance in combat sports, yet the molecular mechanisms underlying training adaptation remain unclear. This study investigated whether changes in circulating myokine–adipokine profiles are associated with aerobic performance adaptation following sport-specific HIIT in trained combat athletes. Forty elite male kickboxers were randomly assigned to a HIIT group (n = 20) or a control group (n = 20). The HIIT group performed an eight-week sport-specific HIIT program in addition to regular training, whereas the control group maintained their usual training routines. Aerobic capacity was assessed using maximal oxygen uptake (VO₂max). Fasting blood samples were collected before and after the intervention to determine circulating apelin, irisin, brain-derived neurotrophic factor (BDNF), myostatin, fibroblast growth factor-21 (FGF21), and adiponectin concentrations. VO₂max increased significantly in the HIIT group compared with the control group (+2.10 ± 1.10 vs. +0.35 ± 0.80 mL·kg⁻¹·min⁻¹, p = 0.001). In addition, apelin, irisin, BDNF, FGF21, and adiponectin increased, whereas myostatin decreased following the intervention. Changes in myostatin were negatively correlated with improvements in VO₂max (r = −0.55, p = 0.007), suggesting that reductions in myostatin may serve as a molecular indicator of aerobic adaptation in combat athletes. Full article

Background/Objectives: Recent guidelines have emphasized the importance of early mobilization and rehabilitation of patients following cardiac surgery. However, studies on the optimal targets and prescription methods for phase I cardiac rehabilitation (CR) are lacking. This study aimed to evaluate the feasibility and utility of an early phase 1 submaximal cardiopulmonary exercise test (CPET) using a recumbent ergometer in patients who have undergone cardiac surgery. Methods: Twenty ambulatory patients who underwent cardiac surgery between December 2021 and February 2023 were referred to the CR department on the fifth postoperative day, and a CR program was initiated. The program was conducted five times a week, with hour-long sessions consisting of warm-up exercises, resistance training, aerobic exercises, and a cool-down period. A recumbent ergometer-based submaximal CPET was performed approximately nine days after the surgery, prior to discharge. Participants initiated the test at 0 W, and the workload was increased by 20 W after 2 min. During the test, researchers evaluated parameters including submaximal peak values of oxygen consumption (VO₂), metabolic equivalents of task, respiratory exchange ratio (RER), blood pressure, heart rate (HR), and rating of perceived exertion (RPE). The grip strength test, 6 min walk test (6MWT), Korean Activity Scale/Index (KASI), EuroQol-5 dimension (EQ-5D), and short-form 36-item health survey (SF-36) values were also measured prior to discharge. Results: Twenty patients (75% male, average age 62.50 ± 1.99 years) underwent CPET at a median of 9.0 (8.0; 12.5) days postoperative. The average exercise duration of the CPET was 411.75 ± 168.25 s. During the test, their submaximal peak VO₂ was 12.32 ± 0.75 mL/kg/min (corresponding to 46.65 ± 2.08% of VO₂ max). The submaximal peak RER was 1.01 (0.98–1.12), and the submaximal peak RPE was 15.00 ± 0.51. Furthermore, the submaximal peak HR was 111.8 ± 3.76 beats/min (equivalent to 70.95 ± 2.09% of age-predicted maximal HR). After adjustment for age and sex, statistically significant positive correlations were observed between the submaximal peak VO₂ and 6MWT, squat endurance test, KASI, EQ-5D, and the physical component summary (PCS) of the SF-36 questionnaire. The 6MWT, squat endurance test, KASI, and PCS of SF-36 showed a correlation coefficient (r) of 0.522 (p = 0.026), 0.628 (p = 0.005), 0.586 (p = 0.011), and 0.546 (p = 0.019), respectively. No significant cardiac events, such as ST elevation/depression or hemodynamic instability, were observed during the test. Conclusions: Our findings suggest that performing recumbent ergometer-based CPET during early phase 1 CR is safe and feasible. These results highlight the potential of recumbent ergometer-based CPET as a valuable tool for guiding the appropriate prescription of early CR programs following hospital discharge in patients undergoing cardiac surgery. Full article

Endurance performance is influenced by age- and sex-specific physiological determinants, while emerging evidence indicates an increasing prevalence of Relative Energy Deficiency in Sport (REDs) among both young and master endurance runners. Despite its clinical relevance, limited data exist on how long-term endurance training modulates REDs risk, skeletal muscle characteristics, and physiological ageing in comparison with inactive individuals. Methods: This cross-sectional study protocol will examine 112 participants stratified by sex, age (20–35 vs. 65–80 years), and training status (endurance runners vs. inactive controls). Cardiorespiratory fitness (VO₂max) is defined as the primary outcome. Secondary outcomes include body composition, musculoskeletal function, biochemical and hormonal markers, and REDs-related screening variables. Assessments will comprise cardiorespiratory testing, DXA-based bone and body composition analysis, isometric knee dynamometry, mobility testing, validated REDs screening tools (LEAF-Q, LEAM-Q, and IOC REDs CAT2), seven-day dietary and training monitoring, venous blood sampling, and skeletal muscle biopsies from the vastus lateralis. Results: This study is designed to generate an integrated overview of physiological, nutritional, metabolic, and muscle-cell characteristics across sex-, age-, and training-specific subgroups. Conclusions: This protocol provides comprehensive insight into how ageing and sex influence endurance physiology and REDs susceptibility and whether long-term endurance training preserves functional capacity across the lifespan. The findings aim to support evidence-based screening, prevention, and targeted interventions for REDs in endurance athletes. Full article

Background/Objectives: This study aimed to evaluate the effects of short-term broccoli powder supplementation on metabolically demanding exercise performance, muscle power, and blood lactate recovery. It also investigated broccoli powder-derived sulforaphane bioavailability and its effects in attenuating exercise-induced oxidative stress. Methods: Seventeen healthy males (age 23.8 ± 4.9 years, height 182.3 ± 6.1 cm, weight 80.0 ± 12.8 kg), in a double-blind crossover design, three weeks apart, consumed ten standard doses of either broccoli powder or spinach powder as a placebo over a period of 2 weeks. They then performed a maximal progressive cycling task with concomitant analysis of expired gas composition. Plasma malondialdehyde (MDA) level was measured before and 60 min after the completion of the task, and blood lactate and muscle power (counter-movement vertical jump (CMJ) performance) were measured before and up to 60 min after exercise. Results: The main findings were that despite urine sulforaphane output being markedly higher following broccoli supplementation (p < 0.05), which confirms effective absorption and systemic availability of the compound, this did not influence exercise-induced changes in plasma MDA concentration, blood lactate dynamics, exercise test performance, or functional recovery measured as muscle power via CMJ performance (p > 0.05). Conclusions: In conclusion, broccoli powder supplementation, despite efficient delivery of sulforaphane, does not seem to either acutely affect performance or modify oxidative stress and recovery from metabolically demanding exercise. Full article

Background: Ice hockey is characterized by repeated short-duration, high-intensity efforts interspersed with brief recovery periods, requiring a complex interaction of aerobic and anaerobic energy systems. The aim of this study was to determine the energetic structure of repeated high-intensity on-ice sprint exercise in ice hockey players by quantifying the relative contributions of the oxidative, glycolytic and ATP–PCr energy systems. Methods: 14 male semi-professional ice hockey players performed the 30–15_IIT followed by the Repeated High-Intensity Effort (RHIE) on-ice. Oxygen uptake was measured breath-by-breath, blood lactate concentration and energy system contributions were estimated using a three-component PCr–La–O₂ model. Results: The RHIE on-ice was characterized by a dominant aerobic contribution (63.1 ± 2.6%), followed by phosphagen metabolism (29.8 ± 2.9%), with a relatively small glycolytic contribution (7.4 ± 1.5%). Conclusions: No significant relationships were observed between maximal oxygen uptake (VO_2max) and the RHIE performance parameters, energy system contributions or lactate responses, except for a moderate relationship between absolute VO_2max and absolute aerobic work. In contrast, parameters determined at the anaerobic threshold showed more consistent relationships with absolute metabolic work. These findings indicate that repeated high-intensity on-ice performance in ice hockey is largely independent of VO_2max and is more closely related to individual energetic profiles and metabolic tolerance. Full article