Sound speed profile (SSP) significantly affects acoustic propagation in the ocean. In this work, the SSP is inverted using compressive sensing (CS) combined with beamforming to indicate the direction of arrivals (DOAs). The travel times and the posit...
Deep learning-based data-driven methods have gained significant attention in underwater acoustic source localization. However, their performance is often constrained by environmental disturbances and the scarcity of real-world underwater acoustic dat...
Localization of emitting sources is a fundamental task in sonar applications. One of the most important factors that affect the localization performance is the sensor–target geometry. The sensor formation problem is usually addressed in related...
The main challenges facing efforts to prevent the transmission of human immunodeficiency virus (HIV) are the lack of access to sexual education services and sexual violence against young women and girls. Vaginal formulations for the prevention of sex...
Vaginal formulations for the prevention of sexually transmitted infections are currently gaining importance in drug development. Polysaccharides, such as chitosan and carrageenan, which have good binding capacity with mucosal tissues, are now include...
The passive estimation of harmonic sound source depth is of great significance for underwater target localization and identification. Passive source depth estimation using a single hydrophone with an unknown seabed geoacoustic property is a crucial c...
Conventional matched-field processing (MFP) for acoustic source localization is sensitive to environmental mismatches because it is based on the wave propagation model and environmental information that is uncertain in reality. In this paper, a mode-...
To localize a moving source in shallow water with a single hydrophone, a passive range localization method based on synthetic aperture beamforming is proposed. First, the horizontal wavenumber spectrum excited by the source is obtained by synthetic a...
Environmental mismatch degrades the performance of source localization and tracking methods in shallow water. One solution is to estimate source parameters and the key environmental parameters simultaneously from the acoustic data. In this paper, an...
A source depth discrimination method based on intensity striations in the frequency–depth plane with a vertical linear array in a shallow water environment is proposed and studied theoretically and experimentally. To quantify the orientation of...
Recently proposed direct position determination (DPD) methods have garnered considerable interest in passive localization due to their excellent positioning accuracy. However, in multiple-target environments, error locations generated by wrong associ...
To solve the poor performance or even failure of the cross-spectrum (CS) method in hydroacoustic weak-target passive velocimetry, a sparse Bayesian learning cross-spectrum method (SBL-CS), combining phase compensation with sparse Bayesian learning (S...
Deep neural networks (DNNs) have been shown to be effective for single sound source localization in shallow water environments. However, multiple source localization is a more challenging task because of the interactions among multiple acoustic signa...
Gridless direction of arrival (DOA) estimation methods have garnered significant attention due to their ability to avoid grid mismatch errors, which can adversely affect the performance of high-resolution DOA estimation algorithms. However, most exis...
Under wideband interference conditions, traditional neural networks often suffer from low accuracy in single-frequency direction-of-arrival (DOA) estimation and face challenges in detecting single-frequency sound sources. To address this limitation,...
A passive time reversal method with a metamodel (PTR-MM) is proposed to improve underwater source localization under ocean conditions. PTR-MM eliminates model mismatch errors by replacing the conventional sound propagation model with a Kriging metamo...
In the shallow-water waveguide environment, the tonal signals radiated by moving targets carry modal interference and Doppler shift information. The modal interference can be used to obtain the time of the closest point of approach (
To address the challenge of estimating the depth of a single-frequency (tonal) source using a vertical line array (VLA) without prior knowledge of seabed parameters, a method called OCMS-D (orthogonality-constrained modal search-based depth estimatio...
Underwater source localization is an important task, especially for real-time operation. Recently, machine learning methods have been combined with supervised learning schemes. This opens new possibilities for underwater source localization. However,...
Underwater acoustic source localization is formulated as a feature learning problem within a machine learning framework, where a data-driven approach directly extracts source distance features from hydroacoustic signals. This study systematically com...
To improve the robustness and computational efficiency of underwater direction-of-arrival (DOA) estimation in complex marine noise environments, this study proposes an improved sparse Bayesian off-grid DOA estimation method under mixed noise. Within...
This study evaluates adaptive spatial matrix filtering (AMF) combined with MUSIC for underwater acoustic direction-of-arrival estimation under strong out-of-sector interference and extends the method to coherent sources by incorporating forward spati...
During corticogenesis, neuronal migration is an essential step for formation of a functional brain, and abnormal migration is known to cause various neurological disorders. Neuronal migration is not just a simple movement of the cell body, but a cons...
The aim of this study was to fabricate celecoxib-loaded chitosan/guar gum (CS/GG) single (SC) and dual (DC) crosslinked hydrogel beads using the ionotropic gelation approach. The prepared formulations were evaluated for entrapment efficiency (EE%), l...
Corneal defects are a major cause of vision loss and require rapid, biocompatible, and effective sealing methods to restore ocular integrity and prevent infection. Current clinical adhesives, such as cyanoacrylate and fibrin glue, are limited by prob...
Today, the synthesis of biocompatible and bioresorbable composite materials such as “polymer matrix-mineral constituent,” which stimulate the natural growth of living tissues and the restoration of damaged parts of the body, is one of the...
Sustained release of antiretroviral drugs is currently the most encouraging strategy for the prevention of the sexual transmission of HIV. Vaginal tablets based on hydrophilic gelling polymers are an interesting dosage form for this purpose, since th...
Black seed oil (BSO) has been used for various therapeutic purposes around the world since ancient eras. It is one of the most prominent oils used in nutraceutical formulations and daily consumption for its significant therapeutic value is common phe...
Commercially available anion exchange membranes were retrieved from VRFB field tests and their degradation due to the various operation conditions is analyzed by in-situ and ex-situ measurements. Ion exchange capacity, permeability and swelling power...
Sialolithiasis mainly affects the oral salivary glands due to the presence of small stones that obstruct the secretion of saliva. The treatment and control of pain and inflammation during the course of this pathology is essential to guarantee the pat...
Women are still at high risk of contracting the human immunodeficiency virus (HIV) virus due to the lack of protection methods under their control, especially in sub-Saharan countries. Polyelectrolyte multilayer smart vaginal films based on chitosan...
The dimensional instability of rubberwood [Hevea brasiliensis (Willd. ex A. Juss.) Müll. Arg.] is one of the major drawbacks that limits its utilization. Therefore, treatment is needed to improve these properties. Hydrothermal treatment in diffe...
This study evaluates the chemical, physical, mechanical, and biological properties of untreated and heat-treated Cryptomeria japonica (Thunb ex L.f.) D.Don wood from the Azores, Portugal. Heat treatment was performed at 212 °C for 2 h following t...
A hydrogel topical patch of neomycin was developed by using sodium alginate (SA) and hydroxyethylcellulose (HEC) as polymers. Free radical polymerization in an aqueous medium was initiated by using acrylic acid (AA) and N,N′-methylenebisacrylam...
Long-term sunlight exposure will cause the accumulation of free radicals in the skin and lead to oxidative damage and aging, antioxidant drugs have gradually become the focus of research, but there is little research on antioxidant drugs for percutan...
Background/Objectives: This study aimed to develop and formulation-design curcumin-loaded buccal films using a green deep eutectic solvent (DES) to improve drug solubility and support localized mucosal delivery, with the help of a Design of Experimen...
Non-biodegradable materials with a low swelling capacity and which are opaque and occlusive are the main problems associated with the clinical performance of some commercially available wound dressings. In this work, a novel biodegradable wound dress...
In the current study, we developed a novel gelatin-based bilayer wound dressing. We used different crosslinking agents to confer unique properties to each layer, obtaining a bioinspired multifunctional hydrofilm suitable for wound healing. First, we...
Grand fir (Abies grandis/Dougl. ex D. Don/Lindl.) represents the North American species that has the potential to replace and complement to some extent several commercial European species, in particular, Norway spruce and silver fir. This is not only...
A promising controlled drug delivery system has been developed based on polymeric buccoadhesive bilayered formulation that uses a drug-free backing layer and a polymeric hydrophilic gel buccoadhesive core layer containing nifedipine. The DSC thermogr...
Medical research explores plant extracts’ properties to obtain potential anticancer drugs. The present study aims to formulate, develop, and characterize the bioadhesive oral films containing Usnea barbata (L.) dry ethanol extract (F-UBE-HPC) a...
Background/Objectives: Epalrestat (EPL), an aldose reductase inhibitor, exhibits poor aqueous solubility and limited ocular bioavailability, which significantly restricts its therapeutic efficacy in the treatment of diabetic retinopathy. To overcome...
The functional physicochemical properties of nicotine (NIC)-loaded composite freeze-dried wafers and solvent-evaporated films comprising hydroxypropylmethylcellulose (HPMC) and sodium alginate (SA), stabilized with magnesium aluminium silicate (MAS),...
We developed a potential composite ocular drug delivery system for the topical administration of diclofenac sodium (DS). The novel carbon dot CDC-HP was synthesized by the pyrolysis of hyaluronic acid and carboxymethyl chitosan through a one-step hyd...
Cystic fibrosis, a multi-organ genetic disease, is characterized by abnormal function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride channel at the apical membrane of several epithelia. In recent years, therapeu...
This work describes the development and characterization of fluorescent nanocomposite hydrogels, with high swelling and absorption capacity, and prepared using a green protocol. These fluorescent materials are obtained by incorporating, for the first...
Time-dependent deformation in nuclear graphite is influenced by the creation and migration of radiation-induced defects in the reactor environment. This study investigates the role of pre-existing defects such as point defect clusters and Mrozowski c...
The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) approach was employed to optimize DTB-loaded nano-emulgel using a central com...
The analysis of the physical and chemical properties of blackcurrant (Ribes nigrum L.), strawberry (Fragaria ananassa Duchesne ex Weston) and raspberry (Rubus idaeus L.) seeds recovered from pomace—food processing waste—was carried out. T...
The physicochemical properties of buccal films are vital for evaluating their suitability for mucosal applications. By focusing on these properties, researchers can enhance the mechanical functionality and mucoadhesion of the films. This study aimed...
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