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Article

726 Views

23 Pages

Study on the Efficacy and Pharmacological Mechanism of Innate Immune STING Pathway Regulators in the Treatment of Ischemic Brain Injury

Chang Liu,
Xiaoqing Wang,
Yueru Zhang,
Songli Yu and
Xiangshi Tan

Pharmaceuticals2025, 18(12), 1775;https://doi.org/10.3390/ph18121775

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21 November 2025

Background/Objectives: The efficacy of ST909, an innate immune cGAS/STING/IRF3 pathway regulator, against ischemic brain injury was investigated, and its pharmacological mechanism was elucidated. Methods: The efficacy and pharmacological mechanism of...

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1 Citations

1,311 Views

25 Pages

Study on the Pharmacological Efficacy and Mechanism of Dual-Target Liposome Complex AD808 Against Alzheimer’s Disease

Chang Liu,
Xiaoqing Wang,
Wei Xu,
Songli Yu,
Yueru Zhang,
Qiming Xu and
Xiangshi Tan

Pharmaceuticals2025, 18(7), 977;https://doi.org/10.3390/ph18070977

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29 June 2025

Background/Objectives: To study the efficacy and pharmacological mechanism of the dual-target liposome complex AD808 in the treatment of Alzheimer’s disease. Methods: Using APP/PS1 mouse models, the therapeutic efficacy and pharmacological mech...

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