2 Results Found

Advanced Search

Select all

Results per page

Select all

Article

2,545 Views

12 Pages

Anti-Trypanosomal Bufadienolides from the Oocytes of the Toad Rhinella alata (Anura, Bufonidae)

Candelario Rodriguez,
Roberto Ibáñez,
Dionisio A. Olmedo,
Michelle Ng,
Carmenza Spadafora,
Armando A. Durant-Archibold and
Marcelino Gutiérrez

Molecules2024, 29(1), 196;https://doi.org/10.3390/molecules29010196

-

29 December 2023

Amphibians are widely known as a prolific source of bioactive metabolites. In this work, we isolated and characterized compounds with antiparasitic activity from the oocytes of the toad Rhinella alata collected in Panama. Bio-guided isolation and str...

Full Article

Article

15 Citations

4,994 Views

14 Pages

Bufadienolides from the Skin Secretions of the Neotropical Toad Rhinella alata (Anura: Bufonidae): Antiprotozoal Activity against Trypanosoma cruzi

Candelario Rodriguez,
Roberto Ibáñez,
Luis Mojica,
Michelle Ng,
Carmenza Spadafora,
Armando A. Durant-Archibold and
Marcelino Gutiérrez

Molecules2021, 26(14), 4217;https://doi.org/10.3390/molecules26144217

-

12 July 2021

Toads in the family Bufonidae contain bufadienolides in their venom, which are characterized by their chemical diversity and high pharmacological potential. American trypanosomiasis is a neglected disease that affects an estimated 8 million people in...

Full Article