Search Results (13,838)

This study examines how regional newspapers in Norway portray schools and the teaching profession, and how such representations may influence teacher recruitment. Drawing on theories of mediatization and discursive power, the analysis reveals that media narratives are ideologically charged and contribute to shaping public perceptions of teaching as a profession in crisis. Structural changes, such as school centralization and free school choice, further complicate recruitment, particularly in rural areas. While negative portrayals may deter potential applicants, they also highlight systemic issues that warrant political attention. The study concludes that media representations might play a significant role in influencing attitudes toward teacher education and recruitment. Full article

Background/Objectives: It is challenging to develop efficient vaccines against intracellular pathogens such as viruses, and since viral infections are one of the main challenges for farmed salmon, a novel vaccine strategy is needed. mRNA vaccines are optimized and approved for humans, but for fish, the mRNA technology is new, and optimization is required to ensure efficient protein expression. We made an mRNA tailored to salmon and studied the effect of modified nucleosides and the length of the poly(A) tail on protein expression from in vitro-transcribed mRNA in CHSE-214 cells, using enhanced green fluorescent protein (EGFP) as a reporter. Methods: Different lengths of the poly(A) tail were tested, and various modified nucleotides were incorporated in the mRNA during in vitro transcription, including pseudouridine (Ψ), N1-methylpseudouridine (m1Ψ), N6-methyladenosine (m6A), 5-methyluridine (m5U), and 5-methylcytidine (m5C). Protein expression was observed in fluorescence microscopy and quantified using flow cytometry. Results: mRNA containing Ψ resulted in the strongest EGFP expression 1–3 days post-transfection (dpt), while EGFP expression from m5C mRNA was high throughout the experiment (<10 dpt). m5U-containing mRNA had low EGFP expression until 6 dpt, but reached the level of m5C mRNA at 10 dpt. The m5U mRNA, however, expressed EGFP at much higher intensity than all the other mRNAs at all time points. Poly(A) tails with lengths of 40, 100, and >100 were tested, and the one with >100 adenines showed the highest expression. The effects of phosphatase treatment and purification of the mRNA were also investigated. Furthermore, EGFP expression was observed in yolk-sac salmon larvae following micro-injection. Conclusions: Our study provides an important basis for the development of efficient mRNA-based vaccines in the future. Full article

Background: A solid understanding of dental and craniofacial anatomy is essential for reliable clinical practice, yet long-term retention of anatomical knowledge is known to decline as students progress through their training. Although digital- and image-based resources are widely used in anatomy education, it remains unclear whether two-dimensional (2D) representations support durable recognition of complex anatomical structures. This study investigated whether tactile engagement with real three-dimensional (3D) anatomical specimens enhances long-term identification accuracy compared with standardized 2D images. Materials and Methods: Eighty-nine fifth-year dental students at the University of Oslo were assessed approximately 2.5 years after completing their formal anatomy course. All students completed two sequential identification tests on the same day: a 2D image-based test followed immediately by an equivalent test using real extracted human teeth and real skull bones. The assessments comprised 28 osteology structures and 14 teeth. Performance between conditions was compared using mixed-effects logistic regression with test modality as a fixed effect and participant and anatomical item as crossed random effects. Results: Overall identification accuracy increased from 52% in the 2D condition to 74% in the 3D tactile condition (p < 0.0001). Mean accuracy for osteology improved from 0.519 (SD = 0.074) to 0.708 (SD = 0.072) (p < 0.0001), while tooth morphology scores increased from 0.535 (SD = 0.097) to 0.795 (SD = 0.110) (p < 0.0001). All individual teeth and nearly all osteological structures showed significantly higher identification accuracy in the 3D condition. The largest gains were observed for structures with low 2D recognition. Conclusions: Tactile interaction with real 3D anatomical specimens substantially enhances long-term recognition of dental and craniofacial anatomy. These findings support the continued integration of hands-on, three-dimensional learning alongside digital resources in dental anatomy education to promote durable anatomical understanding and clinical preparedness. Full article

Recent studies suggest that prolonged participation in formal music programs may be associated with the cultivation of resilience and locus of control (LoC) in music students. Brazilian musicians, who were attending or had attended community-based music programs, and a group of matched, untrained individuals from disadvantaged, urban communities completed the Connor–Davidson Scale of Resilience (RISC), the Craig Locus of Control Scale, and the ABEP 2022—Brazilian Criteria of Economic Classification questionnaire. Results suggested that while musical participation alone was not associated with resilience and LoC scores (model 1), a conditional restriction of the same model (model 2) showed a significant interaction between musical participation, age, and RISC and LoC scores, after controlling for SES. Among musicians, higher age was associated with higher resilience scores and internal LoC. Findings from this exploratory study are discussed in light of the multifaceted nature of community-based music programs, the building blocks of resilience and LoC. We also comment on the potential links between resilience and LoC in relation to musical participation and well-being. Limitations of this study are discussed alongside implications for future research. Full article

Background/Objectives: Adolescent lumbar disc herniation (ALDH) is rare. Evidence on long-term surgical outcomes remains limited. The objective of this study was to evaluate mid- and long-term clinical outcomes following lumbar microdiscectomy in adolescents with lumbar disc herniation (LDH). Methods: A single-institution retrospective cohort study of patients under 19 years who underwent lumbar microdiscectomy over a ten-year period. Baseline clinical and radiological data were obtained from electronic patient records (EPR) and Magnetic Resonance Imaging (MRI). Patient-reported outcomes were collected at follow-up using the Oswestry Disability Index (ODI) as the primary outcome and Numeric Rating Scales (NRS) for back and leg pain and Global Perceived Effect (GPE) as secondary outcomes. Descriptive statistics were used to summarize results. Results: Seventeen of 27 patients (63%) participated. Mean age at surgery was 16.9 years, and mean symptom duration prior to surgery was 11.3 months. All patients underwent disc-preserving microdiscectomy. At a mean follow-up of 67.7 months, mean ODI was 9.5, mean NRS back pain was 2.8, and mean NRS leg pain was 2.3. Fourteen patients (82%) reported being completely recovered or much improved. Conclusions: Lumbar microdiscectomy in adolescents with LDH showed acceptable mid- to long-term outcomes, low disability, and low pain levels at more than five years of follow-up. Clinical and imaging findings resembled those seen in adults, though symptom duration before surgery was prolonged. Full article

Cyber Ranges (CRs) are complex socio-technical ecosystems, combining infrastructure resources, software services, learning mechanisms, and human-in-the-loop processes for cybersecurity training, education, and experimentation. However, their design and representation are conventionally described by diverse architectural representations and a lack of standardization, making them difficult to compare, integrate, and reason in an automated manner. This paper proposes a novel framework that uniquely integrates the structural, functional, informational, and decisional aspects of CR platforms, formalizing them into a common semantic framework. It models the architectural and learning characteristics of CRs, allowing the representation of design choices, operational processes, information resources, and capability development. The ontology is implemented using OWL 2 DL, which includes logical constraints and enables consistency checking and automated reasoning. Validation through instantiation and competency question assessment shows that the model allows for structured querying, traceability across abstraction levels, and capability-level reasoning. The findings indicate that ontology-based modeling can serve as a basis for more formalized CR configuration analysis and capability-focused evaluation of diverse CR platforms. Full article

Microalgae are increasingly recognized as renewable biofactories for producing high-value bioactive molecules. However, their industrial exploitation is limited by their rigid cell walls, metabolite heterogeneity, and the energy-intensive nature of the extraction processes. Recent advances in process-intensification technologies, including microwave-assisted, ultrasound-assisted, enzymatic, pressurized liquid, and supercritical CO₂-based methods, have significantly improved extraction efficiency and selectivity, with reported lipid recoveries exceeding 40–50% in some microalgal systems and carotenoid recoveries approaching 90% under optimized conditions. NADES-assisted systems further enhance mass transfer and solubilization through tailored hydrogen-bonding interactions, enabling selective extraction of polar and semi-polar metabolites under mild conditions. However, limitations remain, including high viscosity, variability in extraction performance, and challenges in solvent recovery and scale-up. This review critically evaluates the extraction efficiency, mechanistic basis, and sustainability of NADES-assisted processes, highlighting key limitations and identifying research priorities for their integration into scalable microalgal biorefinery systems. Full article

In Norway, children are entitled to all individual and collective rights under the UN Convention on the Rights of the Child (CRC), while parents play an important role in facilitating access to these rights. However, conflicts may arise when a teenager’s right to freedom of association clashes with their parents’ religious beliefs and identity. This article studies the ontological (in)security challenge faced by Muslim parents in Norway when their teenage children choose to participate in confirmation rites. The article explores how Muslim parents navigate the tension between their responsibility to pass on religious beliefs and identity to their children and their children’s assertion of the right to freedom of association with peer groups. The study is based on a pilot survey of Muslim parents whose children participated in confirmation rites at the Norwegian Humanist Association (NHA). Full article

Four-dimensional (4D) printing integrates additive manufacturing with stimuli-responsive materials to fabricate biomedical implants and functional healthcare devices that undergo programmed, time-dependent changes in shape or function. Unlike static 3D-printed constructs, 4D-printed systems can respond to clinically relevant stimuli such as temperature, hydration, pH, light (including near-infrared), magnetic fields, or electrical inputs. These triggers drive defined actuation mechanisms, most commonly thermomechanical shape-memory recovery, swelling-induced morphing, and magnetothermal activation. This review synthesizes the principal material platforms used for biomedical 4D printing, including shape-memory polymers and alloys, hydrogels, liquid-crystal elastomers, and responsive composites, and links material choice to device behavior and translational feasibility. Applications are discussed across self-expanding stents, cardiac occluders, tissue-engineered constructs, implantable drug delivery systems, and adaptive wearables. Key translational challenges include sterilization compatibility, manufacturing reproducibility and quality control, safe stimulus delivery, predictable biodegradation and long-term biocompatibility, and regulatory pathway definition. Full article

Anxiety, a common mental disorder, is epidemiologically linked to high dietary sugar intake. However, the underlying neural mechanisms remain poorly understood. Here, using male C57BL/6 mice (n ≥ 10 per group), we show that two-week consumption of sugar-sweetened drinks reliably induced anxiety-like behavior, characterized by reduced center time in the open field test and less open arm exploration in the elevated plus maze. Notably, consumption of sucrose, glucose, or the non-metabolizable glucose analog methyl-α-D-glucopyranoside induced anxiety-like behavior, whereas intake of the artificial sweetener acesulfame potassium (Ace-K) did not. Moreover, after two weeks of exposure to sucrose or glucose but not to Ace-K, c-Fos expression was elevated in glutamatergic neurons of the nucleus of the solitary tract (NTS). Mechanistically, high glucose activated intrinsic excitability and the amplitude of spontaneous excitatory postsynaptic currents in NTS glutamatergic neurons; congruently, selective activation of NTS glutamatergic neurons mimicked anxiety-like behavior in mice, while chemogenetic silencing of these neurons abolished glucose-induced anxiety. Together, our findings demonstrate that NTS glutamatergic neurons activation mediates sugar-induced anxiety. These results suggest that this anxiogenic effect is driven by glucose-related signaling rather than artificial sweet taste perception alone, shedding light on a novel clinical therapy against anxiety. Full article

Situation Awareness (SA) of operators in Cyber Security (CS) has been assumed important for effective incident response in critical infrastructure. Many previous studies have proposed tools and methods to improve SA, but there is a general lack of empirical evidence on the impact of SA on performance in this domain. In this study, we present such empirical evidence from experiments done within the domain of critical infrastructure. Eleven professional CS operators from the power sector participated in a realistic simulated network-related incident response task. SA, experience, and performance were scored for each participant. SA was measured using the Situation Awareness Global Assessment Technique (SAGAT). Statistically significant results confirmed three hypotheses: Higher SA was correlated with higher performance, and longer experience as an operator was correlated with higher performance. Additionally, higher SA is predictive of higher performance independently of longer experience. Accordingly, initial empirical evidence supporting the conjecture that cyber-SA is positively associated with performance now exists. Implications include that further CS research aimed at tool development and operator training should use recognized SA measurements as demonstrated in this study. This study thus contributes to bridging the existing knowledge gap of cyber-SA. Full article

In the sustainability framework, valorization of organic by-products as reservoirs of phytochemicals useful for human health represents a hot topic. Therefore, this study evaluated Norway spruce bark and twigs (NSB, NST), chestnut tree wood (CTW), and pomegranate fruit waste/pomace (PFW) as sources of bioactive compounds by employing green technologies. Microwave-assisted extraction (MAE) and ultrasound-assisted extraction (UAE), applied individually or sequentially, were optimized by modulating solvent composition, temperature, time, microwave power, and ultrasound amplitude. Hydroalcoholic extraction (50% ethanol) combined with MAE yielded the highest phenolic recovery and antioxidant activity across all matrices. PFW exhibited the highest antioxidant activity assessed through FRAP, ORAC, and DPPH assays. Phytochemical profiling by HPLC-DAD identified stilbenes in spruce extracts, ellagic acid in chestnut wood, and ellagic acid and punicalagins in pomegranate waste as major bioactive constituents. Additionally, NSB and PFW exhibited α-amylase inhibitory activity. Antimicrobial testing demonstrated dose-dependent activity against Gram-positive (Staphylococcus epidermidis and Bacillus subtilis) and Gram-negative (Pseudomonas stutzeri) strains, with PFW exhibiting the strongest inhibition and NSB displaying broad-spectrum effects. Total phenolic content changed moderately after 21 days of storage. These results demonstrate that sustainable extraction enables efficient recovery of bioactive compounds from plant by-products, supporting their further functional, dietary, and medicinal applications. Full article

The increasing demand for energy, rising electricity costs, and the growing need to reduce carbon emissions have driven industries toward the adoption of Renewable Energy Sources (RES) and Energy Storage Systems (ESS). However, selecting the most suitable ESS for industrial peak-shaving applications remains a complex decision involving technical, economic, and operational considerations. This paper proposes a practical and structured methodology for ESS selection that integrates conventional performance criteria with Industry 5.0 (I5.0) requirements, emphasizing sustainability, resilience, and human-centric industrial operation. Unlike existing multi-criteria decision-making approaches, the proposed framework reduces reliance on expert-based weighting, improving transparency and reproducibility. The methodology is implemented in two stages: initial KPI-based shortlisting of technologies, followed by detailed comparative performance analysis. A case study conducted in a European tire manufacturing plant compares lithium-ion batteries and flywheel energy storage systems under different peak-shaving strategies. Lithium-ion batteries demonstrated superior performance, covering approximately 80% of demand peaks compared with the 73% achieved by the flywheel system, confirming the effectiveness of the proposed methodology for practical industrial ESS selection. Full article

Soil contamination in Sub-Saharan Africa (SSA) is increasingly driven by rapid industrialization, intensive agriculture, mining activities, and urban expansion, posing significant risks to food safety, ecosystem services, and human livelihoods. Despite the growing scale of the problem, low-cost, locally adaptable remediation technologies are widely available and technically feasible within the region. Organic waste and waste-derived products—such as compost, manure, biochar, vermicompost, digestate, and agro-industrial residues—have emerged as sustainable and cost-effective amendments for the remediation of contaminated soils. These materials can immobilize heavy metals, enhance the microbial degradation of organic pollutants, and improve soil health, making them especially suitable for resource-constrained settings. This review synthesizes the current knowledge on the use of organic waste-based remediation approaches in SSA, highlighting technologies already applied at the laboratory, pilot, and field scales, as well as their effectiveness across different contaminant types. However, despite their demonstrated potential, their widespread adoption remains limited. The primary challenge is not the absence of affordable solutions, but rather the systemic constraints characteristic of many SSA countries, including limited technical capacity, weak policy and regulatory frameworks, low stakeholder awareness, and insufficient financial and institutional support for large-scale implementation. To enable broader uptake, there is a need to strengthen waste segregation and treatment systems, standardize composting and pyrolysis processes, and develop robust regulatory guidelines and certification schemes. Investments in monitoring infrastructure, practitioner training, and knowledge transfer mechanisms will also be critical to translating scientific advances into scalable, field-ready solutions for sustainable soil remediation in SSA. Full article

This study examines how military professionals interpret claims about decision making in volatile, uncertain, complex, and ambiguous (VUCA) environments. A survey of active-duty personnel (N = 225) from the Norwegian Armed Forces (2024–2025) was used to assess whether endorsement of Klein’s 11 decision-making claims reflects a unified construct or several distinct decision-making beliefs. After removing two items with insufficient communalities, exploratory factor analysis (principal axis factoring with Oblimin rotation) was conducted on the remaining nine items. Sampling properties were adequate (KMO = 0.741; Bartlett’s χ² (36) = 282.86, p < 0.001). Comparative model testing indicated that a two-factor structure provided a better fit than a unidimensional model, accounting for 29.24% cumulative variance. The resulting dimensions—Planning/Structure (e.g., “Identify and mitigate risks,” loading 0.618) and Analytic/Evidence-based practices (e.g., “Prefer logic over intuition,” loading 0.556)—showed acceptable internal reliability (α = 0.65 and α ≈ 0.71). These findings suggest that military professionals’ endorsement of Klein’s framework is not unidimensional but instead reflects two complementary attitudes about effective decision making. This bifactorial structure offers a theoretically grounded basis for advancing research on adaptive decision making in the military and other high-stakes operational contexts. Full article