Search Results (13,851)

As demand for energy-efficient buildings grows, the use of expanded polystyrene (EPS) insulation is expected to increase, intensifying the need for material-efficient strategies such as recycling and reuse. This study investigates the technical feasibility, chemical safety, and climate implications of reusing EPS insulation recovered from building and infrastructure applications. EPS boards with service lives exceeding 20 years were collected from demolition sites and characterised for density, compressive strength, thermal conductivity, and hazardous substance content. Measured material properties were compared with historical test reports from 1976 to 2009 to assess long-term performance. The thermal conductivity and compressive strength of the used EPS samples fell within or close to the 95% prediction intervals for the corresponding products at the time of production, indicating limited long-term degradation. No brominated flame retardants or other substances of concern were detected above the detection limits. Life cycle assessment (LCA) results showed that reuse provides greater greenhouse gas (GHG) emission reduction potential than improved recycling alone, primarily through avoided virgin EPS production and reduced processing needs. An important insight from this study is that key material properties of used EPS can be reliably estimated from simple measurements of density, dimensions, and weight, and that direct reuse is feasible for less demanding applications. Additionally, further work is needed to test additional samples from diverse demolition sites across various applications and climates to establish a consistent basis for reuse. Full article

Background/Objectives: Adults with intellectual disability are known to experience complex health needs, including an elevated presence of chronic conditions. Cardiovascular risk factors are a concern, yet the evidence base is fragmented, and the scope and focus of current research are not well understood. Methods: We conducted a scoping review to map the existing evidence on cardiovascular risk factors among adults with intellectual disability. The review included studies reporting on risk factor prevalence as well as participant characteristics (ethnicity, living arrangements, age, sex, and type of disability). Cardiovascular-related outcomes were extracted to clarify the health disparities documented in this population. Results: Searches of seven databases for studies published from 2013 onward yielded 15,598records, of which 85 met the inclusion criteria. Evidence was dominated by cross-sectional studies, with a few randomized controlled trials. Hypertension, Type 2 diabetes and obesity were commonly reported. Patterns appeared to reflect lifestyle, medication effects, genetic syndromes—particularly Down syndrome and Prader–Willi syndrome—and the severity of the disability. A notable share of the studies originated from the United Kingdom and the United States. Findings reveal a complex cardiovascular risk profile, emphasizing the need for tailored prevention and management. Conclusions: Adults with intellectual disability face a substantial burden of cardiovascular risk factors. Evidence on effective interventions remains limited, highlighting a need for targeted, evidence-informed approaches to improve cardiovascular health and long-term outcomes. Full article

Background/Objectives: Ankle–foot orthoses (AFOs) are commonly used to improve gait in children with cerebral palsy (CP), but their effect on specific gait patterns is underreported. This study evaluates the utilization of the Gait Pattern Classification System for Children with Spastic CP (GaP-CP) to investigate the effects of ankle–foot orthoses on gait kinematics, spatio-temporal parameters and the energy cost of walking. Methods: In this retrospective study, 66 ambulatory children with spastic CP underwent 3D gait analysis with and without AFOs or functional electrical stimulation. Gait patterns were classified according to GaP-CP. AFOs were articulated, flexible, or rigid. Thirty-six children also performed a 5 min walk test with gas exchange measurements. Step length, walking speed, and the energy cost of walking were calculated. Gait kinematics were analyzed with statistical nonparametric mapping. Non-parametric statistics were used to investigate orthotic effects for the total group and for each gait pattern. Results: Ankle kinematics improved in swing phase and initial contact (10 degrees less plantarflexion, p < 0.05) for the total group, dropfoot and genu recurvatum. During the stance phase, reduced knee extension in genu recurvatum (by 3 degrees, p < 0.05) and increased knee extension in crouch (by 3 degrees, p < 0.05) were observed. Median changes in non-dimensional step length were clinically significant (>0.039, p ≤ 0.02, effect size ≥ 0.55) for the total group and the dropfoot, genu recurvatum, and crouch subgroups, while changes in most gait indices, walking speed and the energy cost of walking were not clinically significant. Conclusions: The combined use of GaP-CP and kinematic analysis provided new insights into the effects of ankle–foot orthoses on gait. Articulated and flexible orthoses may not have provided adequate support for genu recurvatum and crouch gait, showing a potential value in gait pattern specific orthotic design to optimize gait kinematics. Full article

The rapid integration of distributed solar photovoltaic (PV) generation is reshaping low-voltage distribution grids (LVDGs), creating voltage rise, reverse power flow, and congestion challenges for distribution system operators (DSOs). Flexibility in generation and demand, broadly understood as the capability to adjust generation or consumption in response to variability and uncertainty in net load, is increasingly central to cost-effective grid operation under high PV penetration. This review examines flexibility and controllability options in LVDGs, focusing on voltage regulation methods, supply- and demand-side flexibility resources, and market-based coordination mechanisms. The Norwegian Regulation on Quality of Supply (FoL) provides the regulatory context: it enforces 1 min average voltage compliance, stricter than the 10 min averaging window of EN 50160, making short-duration voltage excursions operationally significant and directly influencing the trade-off between curtailment, grid reinforcement, and local flexibility measures. Inverter-based active–reactive power control emerges as the most cost-effective overvoltage mitigation option, complemented by local battery energy storage systems (BESS) and demand response for congestion relief and energy shifting. Key gaps include limited LV observability, insufficient application of quasi-static time series (QSTS) assessment in planning, and underdeveloped DSO-aggregator coordination frameworks. Combined inverter control, feeder-end storage, and demand-side flexibility can defer costly reinforcements, particularly in rural 230 V IT feeders where voltage constraints dominate. Full article

Disease-specific alpha-synuclein (αsyn) strains have been linked to different synucleinopathies. Current αsyn biomarkers are limited to binary detection of pathogenic αsyn in peripheral tissue biopsies or fluids, limiting differential diagnosis. Hence, there is an urgent need for methods that allow strain-specific detection and characterization of αsyn strain architecture. Notably, luminescent conjugated oligothiophenes (LCOs) have been successfully used to detect distinct protein strain conformers in prion diseases and Alzheimer’s disease, highlighting their utility in differentiating disease-specific amyloid structures. Species-dependent differences in αsyn structure are increasingly recognized as one of the critical aspects that shape how fibrils form, propagate and interact with molecular LCO probes. Here, we evaluate the potential of the LCO h-FTAA to differentiate species-specific αsyn strains and conduct a translational investigation using peripheral cardiac tissue of a gut-first synucleinopathy rodent model. Our in vitro data demonstrate strain-specific probe–fibril interactions, reflecting a differential strain architecture and cellular micro-environment. While h-FTAA binds with comparable efficiency to mouse (mo-) and human (hu-) pre-formed fibrils (PFFs), h-FTAA exhibits markedly lower quantum yield when bound to moPFFs versus huPFFs. Spectral imaging revealed h-FTAA-moPFF binding produces blue-shifted maxima (505–550 nm), contrasting with the red-shifted maxima (545–580 nm) of huPFFs. Fluorescence lifetime imaging microscopy confirmed h-FTAA’s intrinsic sensitivity to species-dependent variations through distinct temporal fluorescence signatures (moPFFs: ~0.60–1.5 ns vs. huPFFs: ~0.65–1.0 ns). Our translational investigation showed h-FTAA binding to peripheral cardiac pathology exhibits comparable red-shifted emission, but distinct fluorescence lifetimes of h-FTAA-bound aggregates in moPFF-injected (~1.0–1.4 ns) versus huPFF-injected (~0.69–0.8 ns) rats. Interestingly, we observed distinct blue-shifted emission profiles in a few selected regions of the heart of moPFF-injected rodents, further characterized by extra-long fluorescence decay shifts (~1.5–1.9 ns), reflecting differences in both aggregate conformation and maturity in moPFF-induced compared with huPFF-induced rats. Taken together, our findings underscore the potential of LCO ligands, like h-FTAA, to enable more precise disease staging and diagnosis through peripheral biopsies, complementing existing αsyn biomarker methods. Full article

Agricultural residues and agro-waste are increasingly recognized as valuable reinforcements for sustainable composite materials. Natural fibers derived from these biomasses offer biodegradability, low density, renewability, and potential environmental benefits. However, their performance and sustainability depend strongly on extraction, surface treatment, and processing conditions. Therefore, evaluating the environmental emissions associated with natural fiber biocomposites is essential before claiming sustainability advantages. In this research, flax, jute, kenaf, and bagasse fibers were extracted and treated using an eco-friendly sodium bicarbonate solution, then incorporated into polylactic acid (PLA) matrix to fabricate biocomposites via injection molding. A life cycle assessment (LCA) was conducted using the ReCiPe midpoint (H) method, with a functional unit defined as “per kg” of manufactured biocomposite. The results revealed that jute fiber composites generated the highest emissions across several impact categories, including climate change (1.290 × 10¹ kg CO₂-Eq), terrestrial ecotoxicity (6.327 × 10¹ kg 1,4-DCB-Eq), human toxicity: carcinogenic effects (1.923 kg 1,4-DCB-Eq), and fossil resource use (3.202 kg oil-Eq). Jute also showed a 3.6% increase in terrestrial ecotoxicity and a 19.5% increase in land compared to flax, although it exhibited a 6.5% lower impact related to bagasse. A ±20% electricity-consumption sensitivity analysis further highlighted the dependence of environmental impacts on processing energy demand. Full article

This paper argues that the most significant challenge artificial intelligence poses to theological anthropology is not ontological but epistemic. Rather than asking whether machines can think, feel, or bear the image of God, this paper redirects attention to the prior question of what happens to the human when core epistemic capacities, judgment, discernment, interpretive authority, and moral reasoning are progressively delegated to computational systems. Drawing on the concept of epistemic automation, understood as the systematic transfer of knowledge-producing functions from human agents to algorithmic processes, this paper develops a threefold analytical framework. First, it distinguishes epistemic authority from ontological status as the more productive locus for theological anthropological inquiry. Second, it introduces the distinction between fluency and understanding as an anthropological boundary condition that AI renders newly visible. Third, it analyses delegated cognition as a form of agency deformation with theological significance. The paper concludes that theological anthropology must move beyond reactive commentary on AI and instead generate a theory of the human under conditions of epistemic transformation. The argument engages constructively with philosophy of technology, social epistemology, and Christian theological traditions to offer a framework applicable across confessional boundaries. Full article

Social workers are an integrated part of the criminal justice system. In this field, criminal justice social workers (CJSWs) face challenges related to structure and professional autonomy. During the COVID-19 pandemic, correctional services (CS) implemented strict infection control measures through early releases, lockdowns in prisons with isolation, and the cessation of visits. This research explores how CJSWs experienced working during the COVID-19 pandemic, with a specific focus on perceived influence on their working conditions, changes in users’ needs, and adaptation to new demands related to infection control. This is a mixed-methods study of a small sample of social workers in Norway’s criminal justice sector (N = 75). Findings indicated that they experienced a negative impact of COVID-19 on their contact with colleagues and their target group, as well as on their ability to provide services to the latter. In addition, there is an indication of a heavier workload for CJSWs during COVID-19. Our results are analysed using the job demand–resource model (JD-R). The results suggest that infection control measures created additional demands and strain on CJSWs in caring for vulnerable and at-risk groups, while at the same time reducing contact with their own colleagues and supervisors, experiencing what we address as a ‘double negative’. Full article

Background: Dyslexia is a reading disorder that is associated with phonological processing and awareness difficulties. However, little is known about phonetic production in dyslexia. Whereas individual differences in speech sound perception were linked to native and foreign speech sound production in typical readers, this remains to be explored in dyslexia. Given the phonetic processing deficits frequently encountered in dyslexia, we aimed to pinpoint potential differences in the acoustic realization of native phonemic production in adults with dyslexia. Methods: Ten adults with dyslexia and ten age-matched typical readers produced 24 native-language minimal voiced–voiceless word pairs across three places of articulation (labial, dental, velar) in a reading task. Acoustic analyses addressed phonemic category size, between-category distance, and voice onset time (VOT). Pseudoword reading performance served as an index of phonological decoding ability. Results: For category size, we observed a trend-level group-by-type interaction (p = 0.059, η² = 0.04): both groups showed larger category sizes for voiced than voiceless consonants, but this difference was numerically larger in typical readers. Between-category distance showed a marginal group effect (p = 0.089, η² = 0.14), with larger differences between categories in dyslexia. VOT showed the expected effect of voicing, but no group differences. Conclusions: Our results indicate broadly preserved speech production in dyslexia, alongside subtle differences in category separation and size in dyslexia, marked by considerable inter-individual variability. Full article

The shortage of qualified teachers across Europe has increased interest in flexible and decentralized pathways into teacher education. This study examines pre-service teachers’ background characteristics and programme-choice priorities when selecting between two study formats at a Norwegian university: a blended learning programme and a face-to-face campus-based programme. Survey data from 108 pre-service teachers revealed significant differences between the groups in age, place of residence, region of origin, prior teaching experience, current teaching employment, and confidence in securing a permanent teaching position. Campus-based students were younger, less experienced, and reported lower confidence in obtaining permanent employment than students in the blended learning programme. Three of fifteen choice-related factors differed significantly between study formats, most notably the importance assigned to programme organization, which was rated higher by blended-learning students. No differences were found for geographic location or for eleven content-related factors. In this sample, blended-learning students were more often from rural areas, and they placed greater value on organizational flexibility, suggesting that flexible formats may be particularly relevant for students balancing work, distance, or other commitments. However, this study is cross-sectional, based on a single institution, and cannot determine broader policy implications or effects on regional teacher supply. Longitudinal and multi-institutional research is needed to assess potential long-term outcomes. Full article

The accessibility of flying drones (unmanned aerial vehicles) presents reproducible and cost-effective methods to monitor submerged aquatic vegetation. In particular, drone-borne topobathymetric LiDAR provides high-resolution (cm-scale), three-dimensional information about the geometry and structure of surveyed areas, allowing for quantification of vegetation volume in addition to bathymetry. For seagrasses, this information can advance research regarding the structure of canopies in relation to blue carbon storage and biodiversity. Here, we demonstrate how drone-borne LiDAR can be used to estimate the habitat volume of eelgrass (Zostera marina) within a sheltered bay in Norway. After classifying LiDAR points using a Random Forest model, we created a Digital Terrain Model of the sea floor and a Digital Surface Model of the eelgrass canopy. From these models, we showed that eelgrass canopy volume can be estimated (between 862 and 1099 m³ across the small study area) and the above-ground carbon stock in living tissue can be quantified (between 96 and 122 kg C). To our knowledge, this is the first study to utilise drone-borne LiDAR to quantify the habitat volume and carbon-storage potential of a marine habitat-forming species like eelgrass, demonstrating a novel methodology for providing reproducible and high-resolution data of submerged aquatic habitats. Full article

We present a parametrised charging infrastructure model developed to support the design of a hybrid electric zero-emission vessel with corresponding charging infrastructure for operation along the Norwegian Coastal Express route. The charging model includes functionalities to analyse the required battery storage capacity and power ratings and locations of charging facilities for achieving battery-electric operation. We demonstrate the use of the charging model to analyse different zero-emission scenarios for the Norwegian Coastal Express route. In the presented example scenarios, the model takes as input the estimated energy demand for a new zero-emission vessel design for the Coastal Express in different weather conditions, and includes functionality to consider realistic port stays based on existing timetables and historical data of delays. The analyses show minimal required battery capacities and illustrate a trade-off between charging power and battery capacity, as well as exemplifying the impact of different timetables and historic deviations on charging and energy delivered from the battery. The charging model presented is general and can be used for other routes than the Norwegian Coastal Express, as a tool for decision-makers to optimize for battery-electric operation whilst keeping the need for onboard storage capacity and charging infrastructure installations at a minimum. Full article

This study examines how regional newspapers in Norway portray schools and the teaching profession, and how such representations may influence teacher recruitment. Drawing on theories of mediatization and discursive power, the analysis reveals that media narratives are ideologically charged and contribute to shaping public perceptions of teaching as a profession in crisis. Structural changes, such as school centralization and free school choice, further complicate recruitment, particularly in rural areas. While negative portrayals may deter potential applicants, they also highlight systemic issues that warrant political attention. The study concludes that media representations might play a significant role in influencing attitudes toward teacher education and recruitment. Full article

Background/Objectives: It is challenging to develop efficient vaccines against intracellular pathogens such as viruses, and since viral infections are one of the main challenges for farmed salmon, a novel vaccine strategy is needed. mRNA vaccines are optimized and approved for humans, but for fish, the mRNA technology is new, and optimization is required to ensure efficient protein expression. We made an mRNA tailored to salmon and studied the effect of modified nucleosides and the length of the poly(A) tail on protein expression from in vitro-transcribed mRNA in CHSE-214 cells, using enhanced green fluorescent protein (EGFP) as a reporter. Methods: Different lengths of the poly(A) tail were tested, and various modified nucleotides were incorporated in the mRNA during in vitro transcription, including pseudouridine (Ψ), N1-methylpseudouridine (m1Ψ), N6-methyladenosine (m6A), 5-methyluridine (m5U), and 5-methylcytidine (m5C). Protein expression was observed in fluorescence microscopy and quantified using flow cytometry. Results: mRNA containing Ψ resulted in the strongest EGFP expression 1–3 days post-transfection (dpt), while EGFP expression from m5C mRNA was high throughout the experiment (<10 dpt). m5U-containing mRNA had low EGFP expression until 6 dpt, but reached the level of m5C mRNA at 10 dpt. The m5U mRNA, however, expressed EGFP at much higher intensity than all the other mRNAs at all time points. Poly(A) tails with lengths of 40, 100, and >100 were tested, and the one with >100 adenines showed the highest expression. The effects of phosphatase treatment and purification of the mRNA were also investigated. Furthermore, EGFP expression was observed in yolk-sac salmon larvae following micro-injection. Conclusions: Our study provides an important basis for the development of efficient mRNA-based vaccines in the future. Full article