Search Results (93)

Lassa fever, a viral hemorrhagic illness that first came into the limelight as a clinical entity in 1969 when it was discovered in Northern Nigeria, is now found in other West African countries such as Sierra Leone, Liberia, Guinea, Togo, and the Benin Republic. Over the years, the disease, which is primarily transmitted from contact with infected mastomys rodents to humans, has the capability of secondary human-to-human transmission with significant morbidity and mortality, especially in healthcare settings. The disease is typically characterized by seasonal outbreaks, which peak during the dry season months of December to March. Lassa fever significantly impacts public health and the socioeconomic life of people in affected communities. In Nigeria, the Integrated Disease Surveillance and Response Strategy (IDSR), along with other medical countermeasures, have been employed to curtail the impact of the disease in endemic regions of Nigeria and other West Africa countries. The one-health approach to combat the disease is a promising strategy. This, along with the hope of a safe and effective vaccine, is a ray of hope on the horizon for public health authorities in Nigeria and other West African countries that the battle against Lassa fever might indeed end sooner than later. Full article

Sterculia foetida L., commonly known as the Java olive, is a tropical tree species native to regions of East Africa, tropical Asia, and northern Australia. This study employs species distribution modeling (SDM) to predict the potential geographic distribution of S. foetida under current and future climate scenarios. Using 1425 occurrence data and 19 environmental variables, we applied an ensemble modelling approach of three algorithms: Boosting Regression Trees (BRT), Generalized Linear Model (GLM), and Random Forests (RF), to generate distribution maps. Our models showed high accuracy (mean AUC = 0.98) to indicate that S. foetida has a broad ecological niche, with high suitability in tropical and subtropical regions of north Australia (New Guinea and Papua), Southeast Asia (India, Thailand, Myanmar, Taiwan, Philippines, Malaysia, Sri Lanka), Oman and Yemen in the southwest of Asia, Central Africa (Guinea, Ghana, Nigeria, Congo, Kenya and Tanzania), the Greater and Lesser Antilles, Mesoamerica, and the north of South America (Colombia, Panama, Venezuela, Ecuador and Brazil). Indeed, the probability of occurrence of S. foetida positively correlates with the Maximum temperature of warmest month (bio5), Mean temperature of wettest quarter (bio8) and Precipitation of wettest month (bio13). The model results showed a suitability area of 4,744,653 km², representing 37.86% of the total study area, classified into Low (14.12%), Moderate (8.71%), and High suitability (15.02%). Furthermore, the study found that habitat suitability for S. foetida showed similar trends under both near future climate scenarios (SSP1-2.6 and SSP5-8.5 for 2041–2060), with a slight loss in potential distribution (0.24% and 0.25%, respectively) and moderate gains (1.98% and 2.12%). In the far future (2061–2080), the low scenario (SSP1-2.6) indicated a 0.29% loss and a 2.52% gain, while the high scenario (SSP5-8.5) showed a more dramatic increase in both loss (0.6%) and gain areas (3.79%). These findings are crucial for conservation planning and management, particularly in regions where S. foetida is considered invasive and could become problematic. The study underscores the importance of incorporating climate change projections in SDM to better understand species invasiveness dynamics and inform biodiversity conservation strategies. Full article

Hydrological extremes, particularly floods, are becoming prevalent in parts of Nigeria. During the 2022 rainy season, Nigeria experienced a devastating riverine flood with severe societal impacts. However, the principal factors contributing to riverine flooding in Nigeria remain debatable, necessitating data-driven and policy-relevant studies to quantify the primary causes of riverine floods in Nigeria. In this study, we applied remote sensing techniques and climate data to characterize the 2022 flood event in Nigeria by quantifying the flooded areas, the number of people affected per state, and riverine flood risk assessment. We investigated rainfall and soil moisture anomalies during the flood event and inferred the contribution of the opening of the Lagdo Dam, in Cameroon, to the severity of the flood event. Our results show that large parts of Cameroon and northern Nigeria experienced above-average rainfall during the 2022 rainy season, contributing to soil saturation. About 50,000 ha of land were flooded in Nigeria between July and August; however, following the opening of the Lagdo Dam in September, the flood extent spiked to 200,000 ha (i.e., about 300% increase), suggesting that excess water from the Lagdo Dam, coupled with inadequate drainage infrastructure, amplified the flood extent in Nigeria. Flooded areas were more extensive in northern Nigeria than in southern regions; however, due to denser settlements in flood-prone areas, Anambra State in southeastern Nigeria was the most affected in terms of people impacted. Therefore, besides rainfall changes and inadequate drainage infrastructures leading to the inundation of the major rivers in Nigeria and their tributaries, we also ranked poor town planning against the population density per square meter as a critical factor that amplifies the societal impacts of flooding in Nigeria. Finally, based on the 2022 conditions and the available pre-flood population data, an estimated number of 105,000 people are at critical risk of riverine flooding in Nigeria. Full article

Marek’s disease (MD) is a highly contagious and oncogenic viral disease of poultry, causing significant economic losses due to mortality and reduced performance. The rapid evolution of Marek’s disease virus (MDV) has been reported in poultry farms, often overcoming vaccination and leading to disease outbreaks. This study aimed to detect and molecularly characterize circulating MDV strains in Tanzania, with a focus on their genetic relationship with the vaccine strains currently in use (HVT and CVI988). Samples were collected from six livestock representative zones in Tanzania (Central, Eastern, Southern, Southern Highlands, Lake, and Northern Zone) and analyzed using polymerase chain reaction (PCR) and sequencing of key oncogenic genes (meq, pp38, and vIL-8). Phylogenetic analysis was conducted using MEGA 12 software to determine the genetic relationships between Tanzanian isolates and MDV strains from Africa and other continents. The results confirm the widespread circulation of MDV in Tanzania, with an overall prevalence of 18.08% across all surveyed zones. Molecular characterization of the meq, pp38, and vIL-8 genes revealed high sequence similarity with previously reported MDV strains from Egypt, Nigeria, Israel, and China, with clustering observed in the phylogenetic analysis. Notably, Tanzanian MDV strains exhibited amino acid substitutions associated with increased virulence, particularly in the meq gene, which plays a crucial role in MDV-induced tumorigenesis. These findings suggest that MDV strains in Tanzania have undergone genetic changes that could potentially affect vaccine efficacy. Therefore, this study provides valuable information for vaccine manufacturers, poultry farmers, and policymakers in Tanzania, enabling informed decisions when selecting vaccines for MD control. Full article

Background: Vaccination is a proven and safe method for combating COVID-19; however, coverage remains low in many low- and middle-income countries, including Nigeria. There is also a lack of contextual evidence regarding the public perception of and willingness to receive vaccines. This study aims to contribute to efforts to optimize the vaccination coverage and improve public health in northern Nigeria. Objective: This study investigated the perceptions of COVID-19 vaccination and willingness to uptake the vaccine in northern Nigeria, aiming to identify strategies for optimizing coverage and enhancing vaccination rates. Methods: A cross-sectional household survey was conducted across the Federal Capital Territory and five northern states in Nigeria. The survey assessed the respondents’ perceptions of COVID-19, their knowledge of the COVID-19 vaccine, and their willingness to be vaccinated. Descriptive and inferential (multivariate logistic regression) statistical analyses were employed to characterize the population and identify predictors of vaccine uptake. Results: The mean age of the respondents was 28.00 years. The majority reported at least one piece of misinformation regarding COVID-19. While awareness of the vaccine was high, its actual uptake was low, and future willingness to receive the vaccine was also limited. Employment status emerged as a significant predictor of vaccine uptake, as determined through the multivariate analysis. Furthermore, collaboration with NGOs and community-based organizations (CBOs) was identified as the most effective strategy for enhancing vaccine uptake. Conclusions: This study found a concerningly low willingness to receive the COVID-19 vaccine among participants in northern Nigeria. To address this issue, we recommend establishing partnerships with NGOs and CBOs, implementing extensive public awareness campaigns, and conducting community outreach programs. These efforts should focus on dispelling misinformation, building community trust, and promoting vaccine uptake through culturally appropriate communication materials. Full article

Cowpea (Vigna unguiculata) is a vital crop in sub-Saharan Africa, but the legume pod borer (LPB), Maruca vitrata, can cause over 80% yield losses. Natural resistance to this lepidopteran pest is absent in cowpea germplasm, and insecticides are ineffective due to the pest’s cryptic behavior. To address this, a genetically modified (GM) cowpea expressing the cry1Ab protein from Bacillus thuringiensis (Bt) was developed, providing complete LPB resistance. This Bt cowpea, commercialized as Sampea 20-T in Nigeria, was recently approved in Ghana as Songotra T. To evaluate its performance and the financial returns of its cultivation, field trials were conducted across multiple locations in northern Ghana to compare it to the non-transgenic Songotra control and two commercial cultivars, Kirkhouse-Benga and Wang-Kae. Songotra T exhibited protection against LPB infestations and damage, achieving a grain yield of 2534 kg/ha compared to 1414–1757 kg/ha for the other entries. As expected, non-LPB pest infestations and damage were similar across all entries. Economic analysis revealed that Songotra T had the highest return on investment (464%), outperforming the other tested cultivars (214%). These results demonstrate the potential of GM crops to enhance yields and profitability for resource-poor farmers, underscoring the value of biotechnology for addressing critical agricultural challenges. Full article

Cryptosporidium species are protozoan parasites of veterinary and medical importance that infect a wide range of vertebrates globally. Primarily, the mode of infection is typically ingestion of sporulated oocysts, and the risk of transmission to susceptible host is increased by environmental contamination with sporulated oocysts. This systematic review aims to provide a summary of the available data on Cryptosporidium genotypes in Africa. A systematic research of literature on four electronic databases, including Scopus Web of Science, Science Direct, and AJOL, was performed for the determination of Cryptosporidium genotypes in animal and human hosts across Africa between January 2000 to August 2023. All published studies were screened based on the inclusion and exclusion criteria. Overall, 131 Cryptosporidium genotypes were generated from the 47 articles included in this study, which cut across 14 African countries. Cryptosporidium genotypes were reported across all regions within the African continent, such as northern, eastern, western, central, and southern Africa. Cryptosporidium hominis (Ia, Ib, Id, Ie, If, Ih, Ii, and Ik) genotypes were the most dominant, with C. hominis subfamily Ia genotypes reported across all African regions, which indicates high diversity of these subfamilies on the continent. Cryptosporidium parvum (IIa, IIb, IIc, IId, IIe, IIm, and IIi) genotypes were the second dominant genotypes reported, with C. parvum subfamily IIa genotypes having a high diversity across all the African regions with the exception of southern Africa. C. parvum subfamily IIc (IIcA5G3b), which is known to circulate among humans, was reported in a study on dogs in Nigeria. Other documented species of Cryptosporidium with known subtypes in Africa include C. meleagridis (IIIb, IIId, and IIIg), C. cuniculus (Vb), C. ubiquitum (XIIa), C.), and C. erinacei (XIIIa) genotypes. In conclusion, findings from this review have elucidated the Cryptosporidium species and subtypes within the African continent across humans and multiple animal hosts, implying the diversity of this parasites and its ability to infect wide host ranges. Full article

A guild is an association of artisans or merchants that oversee their craft or trade within a particular territory. In many cultures, building guilds have played a major role in the realisation and maintenance of earth buildings, as well as in the standardisation and dissemination of skills in the building trade. Zaria, in northern Nigeria, is one such traditional settlement where an earth building guild (magina) once played these key roles. Although the guild still exists and traditional titles are still bestowed to members of the guild, its role has changed significantly. Causes for this change are multifaceted but related, as identified during the fieldwork. The aim of this article is to present findings on the changing roles of the earth building guild (magina) in Zaria and how this change is affecting both the practice of earthen architecture and conservation of earth buildings in the city. This study began in 2021 whilst working on a conservation of earth building in Zaria, which involved the engagement of traditional builders (magina) from Zaria, led by Katukan Magina (deputy chief builder) and a member of the earth building guild from Djenne, Mali (Boubacar Kouroumanse). A deeper interest in the Zaria building guild ensued, which led to the further research presented in this article. The review of the existing literature provided a historical background to the Zaria building guild (magina). A comparative analysis of the literature and data generated from interviews and condition surveys were use for the identification of the changes that occur over time. Similarly, a proposal for positive change within the building guild was proposed using an example of a UNESCO World Heritage Site. Full article

Northern Nigeria has had historically low antenatal care (ANC) utilization rates with poor health outcomes. Previous studies have shown that group antenatal care (gANC) improves ANC behavior and pregnancy outcomes. The gANC has been adopted in Kaduna and Kano States, Nigeria. This paper presents baseline findings from the implementation of the gANC program in Kaduna and Kano States, Nigeria, based on data collected from 1269 and 1200 pregnant women, respectively, from March to April 2024. Analyses of sociodemographic and pregnancy behavior data were performed. Participants were mostly between the age of 19 and 31 years, married or living with a partner, with over 50% having their own businesses. Over 62% and 34% had completed secondary- or higher-level education, with 60% and 80% living in urban areas in Kaduna and Kano States, respectively. In Kano State, >60% of the women had their last delivery at home, with 41.6% not assisted by a skilled birth attendant. In Kaduna, >63% delivered in the hospital and >50% had skilled attendance during labor. Almost half had not used contraceptives previously. This study has provided baseline evaluation data for the implementation of gANC in two states in Nigeria. Subsequent longitudinal data will examine the impact of gANC utilization on perinatal outcomes and contraceptive behavior to inform the scaling of the program in the country. Full article

The United States Centers for Disease Control and Prevention (CDC) has categorized Clostridioides difficile infection (CDI) as a significant concern in extended-care facilities, hospitals, and outpatient clinics. However, little is known about CDI in low- and middle-income countries. This study determined CDI prevalence and impact in outpatient adults presenting with diarrhea in Nigeria. Toxigenic culture and PCR were used to detect and validate C. difficile. Prior antibiotic use, medical history, and demographic data were also obtained. Descriptive and inferential statistics were used for data analysis. The patient demographics were 35.48% (22/62) for the 18–24 years age group and 32.26% (20/62) for both the 25–30 years age group and the 31+ years group, with an average age of 29.7 years. Forty-eight percent of the patients (30/62) tested positive for CDI, and the prevalence increased with age. Most patients (86.67%, 52/60) reported moderate/severe cases of diarrhea and 67.7% had no knowledge of antibiotics. The results showed that 62.30% of the cases were hospitalized with the duration of diarrhea being significantly associated (r = 0.98, p ˂ 0.001) with the length of hospitalization. These results suggest that C. difficile is common among diarrhea patients in this population and that Nigerian hospitals’ infection prevention and control measures must include this pathogen. Full article

The problem of insecurity is a global phenomenon that has several forms like terrorism, banditry, kidnappings, etc. Insecurity has taken hold in the Sub-Saharan Region of West Africa, especially in Nigeria, for over two decades. Nigeria’s security crisis is more pronounced in the Northern Region, with a new wave in the North-Central Region of Nigeria. It is herculean to assess insecurity in the North-Central Region of Nigeria because of the region’s fuzzy or imprecise nature of insecurity. This constitutes the rationale for deploying the Fermatean fuzzy technique to assess insecurity due to the capacity of the Fermatean fuzzy scheme to handle imprecision. To this end, a new Fermatean fuzzy distance metric is presented to evaluate insecurity in the North-Central Region of Nigeria using a multi-criteria decision-making technique. To express the logic for creating the new Fermatean fuzzy distance metric, some existing Fermatean fuzzy distance metrics are discussed, along with their drawbacks. The mathematical properties of the new technique are discussed, and the new method is applied computationally to assess insecurity in the North-Central Region of Nigeria. The data for the security assessment are collected via Fermatean fuzzy linguistic variables using the opinions of security experts and analyzed using the technique for order of preference by similarity to ideal solution, which is a commonly used multi-criteria decision-making method. Finally, the numerical validity of the new technique is expressed with comparative results, and the finding shows the benefit of the new distance approach over the existing methodologies. The outcome of the work will provide reliable traveling advisories for safe voyages within the region. Full article

Increasing delays in the onset of the rainy season and extended dry spells in the Nigerian savannas are complicating the determination of optimal planting dates for rain-fed crops, which increases risks for farmers. This study evaluated the impact of planting dates on soybean [Glycine max (L.) Merr.] performance to identify optimal planting dates for different soybean varieties in two agroecological zones (AEZs) of Nigeria. The study involved six planting dates (15 June, 22 June, 29 June, 6 July, 13 July, and 20 July) and three soybean varieties (TGX-1835-10E, TGX-1951-3F, TGX-1904-6F). Results showed significant differences in growth and yield parameters based on location, variety, and planting date. In the Sudan savanna (SS), AEZ at BUK-Kano, optimal yields (>1500 kg ha⁻¹) were achieved when planting TGX-1835-10E and TGX-1951-3F from 15 to 29 June and TGX-1904-6F on 15 June. Planting beyond 29 June reduces yields by 12–55% for TGX-1835-10E and 27–63% for TGX-1951-3F. For TGX-1904-6F, planting after 15 June reduces yields by 27–90%. In the Northern Guinea savanna (NGS) AEZ at Zaria, optimal yields (>1500 kg ha⁻¹) were obtained when planting TGX-1835-10E and TGX-1951-3F from 15 June to 6 July, and TGX-1904-6F between 15 to 29 June. Delaying planting beyond these dates significantly reduced yields by 18–31% for TGX-1835-10E and 12–20% for TGX-1951-3F and 10–41% for TGX-1904-6F. Full article

Names and naming practices convey various nuances of meaning in the Bette sociocultural setting. Against this significant backdrop, this study examines proverbial names as figurative and overt communicative strategies among the Bette people of northern Cross River State in south-eastern Nigeria. The qualitative data were elicited through semi-structured interviews and informal interactions from purposively selected twenty name-givers and ten name-bearers of Bette proverbial names. Data were analysed using the ethnopragmatic theory, an approach to language study that sees culture as playing a central explanatory role in meaning-making. Besides functioning as discursive strategies through which people’s worldview is embedded, proverbial names serve as sociocultural sites through which interpersonal relationships are performatively constructed and maintained. This study enriches our understanding of how the Bette people use proverbial names as tools of social control to perform gender, strengthen communal bonds, enhance peaceful coexistence, and enact Indigenous worldview among themselves. Full article

Chikungunya and dengue are arboviral diseases transmitted by mosquitoes that have been increasingly recognized as public health concerns in Sub-Saharan Africa. Several studies conducted in Nigeria and other West African countries have revealed the seroprevalence burden and cocirculation of antibodies against mosquito-borne infections, thereby revealing a significant burden and clinical outcome complexities that have largely gone undetected. The current research study has important implications for disease surveillance, prevention strategies, and healthcare planning in Nigeria and other Sub-Saharan countries. A cross-sectional study was conducted on 871 outpatients and pregnant women from three regions of Nigeria. CHIKV and DENV immunoblot molecular diagnostic assays were used to analyze the serum samples for the presence of arboviral antibody serological markers IgG (Mikrogen Diagnostik, Germany) with DENV nonstructural protein 1 and DENV Equad and CHIKV virus-like particles (VLPs), according to the manufacturer’s instructions. A total of 871 participants were recruited from three geographical regions in Nigeria. Among them, 17.5% (152/871) were from Abia (southern Nigeria), 34.4% (300/871) were from Kaduna (northern Nigeria), and 48.1% (419/871) were from Nasarawa (central Nigeria). The ages of the participants ranged from 0 months to 80 years, with a mean age of 36.6 years. Of the 871 subjects, 71.0% (619/871) were female, and 29.0% (252/871) were male. The overall cohort detectable antibody seropositivity against CHIKV was 64.9% (565/871), 95% CI (61.74–68.06); DENV, 44.7% (389/871), 95% CI (41.41–47.99); and CHIKV-DENV cocirculation antibodies, 31.6% (95% CI 29–35). This study highlighted the unpredictably high seroprevalence, expansion, magnitude, and undetected burden of chikungunya and dengue in Nigeria. Full article

The Tiga Dam, a primary hydraulic structure in northern Nigeria, is subjected to intense hydrological stress during the rainy season, posing potential risks to its structural integrity. This study investigates the geotechnical properties and stability of the Tiga Dam in Kano State, Nigeria. Twelve soil samples from the downstream area were analyzed for specific gravity, grain size distribution, Atterberg limits, compaction parameters, permeability, and shear strength. The dam’s stability was assessed using Plaxis 2D under various reservoir conditions. Soil erodibility was evaluated using the Revised Universal Soil Loss Equation (RUSLE), and a linear regression model with noise was developed to predict soil expansion rates. The results showed heterogeneous soil properties, with specific gravity ranging from 2.11 to 2.63 and permeability from 3.40 × 10⁻⁹ to 1.49 × 10⁻⁷ m/s. Stability analysis revealed factors of safety of 1.322, 1.006, 1.002, and 1.147 for high reservoir, rapid drawdown, slow drawdown, and low reservoir conditions, respectively. The RUSLE K factor ranged from 0.055 to 0.145, indicating low to moderate soil erodibility. The expansion rate model demonstrated high accuracy (R² = 0.989) in predicting seasonal and long-term soil expansion trends, with peak rates increasing from 16.94 mm/month in 2010–2013 to 19.45 mm/month in 2017–2020. This comprehensive analysis provides crucial insights into the Tiga Dam’s geotechnical behavior, highlighting potential vulnerabilities and the need for targeted management strategies to ensure long-term stability and safety. Full article