Search Results (1,987)

Wheat blast, caused by Magnaporthe oryzae pathotype Triticum (MoT), is an emerging fungal disease that poses a serious threat to global wheat production. In Zambia, where wheat is increasingly becoming a vital component for food and nutritional security, the emergence and spread of wheat blast is a growing concern under the influence of climate and agricultural practices changes. This review assesses the risk of wheat blast expansion in Zambia by examining regional climatic trends, future climate projections, crop suitability, and the ecological requirements of MoT. Potential disease hotspots are identified, and integrated management strategies, including chemical, cultural, and biotechnological approaches are evaluated. The review highlights the urgent need for coordinated disease surveillance, the development and deployment of resistant cultivars, and climate-resilient farming practices. By consolidating current knowledge and outlining sustainable management strategies, this paper aims to support effective disease mitigation and safeguard wheat production in Zambia in the face of climate change. Full article

Greenhouse gas emissions from sanitation systems remain underquantified, particularly when considering the entire service chain. Previous studies have largely focused on emissions from containment, with limited attention to later stages such as collection, transport, treatment and disposal. To address this gap, this research comprehensively estimates greenhouse gas (GHG) emissions from sanitation systems in Lahan municipality, Nepal. We used an extended version of the IPCC-based Tier-1 approach. Data collection included a household survey and key informant interviews. In scenario A, the baseline total annual emissions are 8.7 Gg CO₂e, mostly from the digestion of faecal sludge in the containment (7.3 Gg CO₂e). In scenario B, when a projected faecal sludge treatment plant (FSTP) is built and in operation, annual emissions reach 10.0 Gg CO₂e, driven by methane emitted by the anaerobic digester in the plant. Scenario C considers climate mitigation strategies: increasing the share of households emptying their containments, increased emptying frequency and adding of methane capture in the FSTP. This can reduce annual emissions to 7.9 Gg CO₂e per year, which is 21% less than in scenario B. Our results suggest that methane capture in the FSTP is the most critical mitigation strategy. Full article

The threat of antimicrobial resistance in aquatic environments, particularly riverine systems, is escalating, in part due to effluents discharged from healthcare facilities. This issue has been recognized not only in Japan but also in other Asian countries such as Indonesia and Nepal. Nevertheless, existing research remains limited, prompting an investigation into the prevalence of antimicrobial-resistant bacteria in the upstream and downstream sites of environmental rivers. In 2024, six samples were collected from three rivers in Hyogo Prefecture, Japan; five samples from five river sites in Indonesia; and three samples from downstream sites of rivers in Kathmandu, Nepal. These samples were subjected to selective culture–based Next Generation Sequencing and resistome analyses, based exclusively on the selective culture of bacteria propagated on CHROMagar ESBL plates. In Japan and Indonesia, Pseudomonas, Stenotrophomonas and Acinetobacter were frequently detected, whereas Klebsiella was overwhelmingly predominant in Nepal. Significant differences in the similarity of bacterial community composition among sampling sites across the three countries were observed (p < 0.001). Notably, Nepal exhibited the highest abundance level of antimicrobial resistance genes among the three countries, largely consisting of β-lactam resistance genes. In conclusion, these analyses elucidated substantial differences in bacterial community composition and degrees of environmental contamination. Full article

Ecological resettlement (ER), or conservation-led displacement, is widely implemented to safeguard biodiversity but often produces complex socio-ecological outcomes. This study assessed the environmental justice (both social and ecological) impacts of ER in Nepal’s Terai Arc Landscape (TAL) using an enhanced (including social, ecological, and environmental aspects) environmental justice (EJ) framework. Data were collected from 240 households across all resettled villages within the Chitwan and Parsa National Parks (NPs) of Nepal through household interviews, key informant interviews, focus groups, and field observations, supplemented by policy reviews, reports, and unpublished documents. Household demographics indicated an average family size of 5.5, gender parity (664 females, 658 males), and diverse caste/ethnic composition (ethnic: 146 households; higher caste: 64; lower caste: 6). Wealth distribution and literacy were uneven, with disparities in land ownership, assets, and social positions. Social and ecological justice outcomes were analysed using chi-square and McNemar tests. We observed a significant difference (p < 0.05) in substantive justice (food, shelter, clothing, and security) attributes before and after the resettlements. Similarly, significant improvements post-resettlement were observed in procedural and recognition justice: participation in decision-making increased from 43% to 62% (χ² = 12.34, p < 0.05). However, recognition of Indigenous knowledge and FPIC rights remained low, with 93% of households reporting inadequate acknowledgment (χ² = 198.5, p < 0.05). Distributive justice indicators, including access to compensation and forest resources, showed mixed outcomes, with 52% reporting fair compensation and 48% citing inequities (p < 0.05). Ecological outcomes also shifted significantly: forest cover decreased in 65% of surveyed areas post-resettlement, while grassland extent increased in 28% (χ² = 27.4, p < 0.05). Water source accessibility declined for 48% of households (χ² = 21.6, p < 0.05), and bushfire incidence decreased by 15% (χ² = 9.8, p < 0.05). Composite scoring revealed strong linkages between social justice deficits and ecological downturn in the resettled areas, suggesting that inadequate participation, recognition, inequitable compensation, and ecological degradation shift the issues from parks to the outside and exacerbate environmental vulnerability. These findings demonstrate that ER can achieve partial ecological objectives inside the parks but often perpetuates social inequities and ecological downturn in the resettled areas, undermining the long-term sustainability of the socio-ecological landscape. The study highlights the critical need to integrate social justice, participatory governance, and ecological monitoring into resettlement planning. Future policies should be grounded in the understanding that conservation effectiveness and social equity are mutually reinforcing, and that ignoring justice dimensions risks undermining both biodiversity outcomes and human wellbeing. Full article

Assessment of landslide risk is crucial given the substantial related economic losses and infrastructure damage in mountain areas every year. Particularly, the Sagarmatha National Park (SNP), a key destination for Himalayan glacier tourism, remains relatively understudied in this context. Existing studies primarily focus on regional inventories or simply inventory landslides and lack tourism-specific hazard assessment. This study evaluates landslide distribution, its controlling factors, and the exposure of infrastructure to varying degrees of landslide susceptibility in SNP. A blind inventory of 680 landslides and twelve conditioning factors, including six topographic and six non-topographic variables, were analyzed using Frequency Ratio (FR), Logistic Regression (LR), and Random Forest (RF) models. In addition, spatial overlay analysis was employed to assess the degree of infrastructure exposure. Results indicate that Land Surface Temperature (LST) is the most dominant factor influencing landslides occurrence, followed by rainfall, elevation, and slope, along with specific aspects like south and west and, land cover class like Barren land and Alpine meadows. Random Forest achieved the highest predictive accuracy (91%), outperforming both Logistic Regression (87%) and Frequency Ratio (84%). Exposure assessment of key tourism infrastructure indicates that trekking routes, helipads, buildings, campsites, and bridges are subject to varying levels of landslide risk. Although only 2.73 km (0.52%) of trekking routes intersect active landslide scars, 147 km (28%) lie within high-exposure zones. Consequently, both typical and paraglacial landslides threaten access to glacier tourism destinations, highlighting significant implications for Nepal’s tourism. Full article

This study examines the seismic stability of an underground powerhouse cavern located in the Lesser Himalayan region of Nepal. Both static and seismic loading conditions are analyzed using the finite element method (FEM) and the distinct element method (DEM). Rock mass properties are derived from field investigations and laboratory testing, while empirical correlations are applied to estimate rock mass strength and deformation modulus. Pseudo-static analyses are performed using the FEM-based software Rock and Soil-2-Dimensionsl (RS²) Version 11.027, and dynamic analyses are conducted using the DEM-based software Universal Distinct Element Code (UDEC) Version 5.0 to evaluate deformation and stress redistribution around the cavern. Seismic fragility curves are developed to quantify the probability of damage under varying seismic intensities. Results indicate that a peak ground acceleration (PGA) of 0.25 g increases cavern wall deformation by approximately 15–20 mm compared to static conditions. Fragility analysis shows a probability exceeding 68% for slight damage, while the probability of collapse remains low at approximately 1.7%. Seismic loading also significantly alters stress redistribution along the cavern boundary. Overall, the combined use of numerical modeling and fragility analysis provides a probabilistic framework for assessing seismic risk in underground caverns, offering valuable insights for the design and safety evaluation of hydropower projects in seismically active Himalayan regions. Full article

Hydropower plants remain strategic assets for grid stability and decarbonization, with hydraulic turbines governing conversion efficiency, reliability, and environmental performance. This systematic review synthesizes recent methodologies for evaluating and optimizing turbine operation and maintenance to enhance efficiency, reduce impacts, and extend service life. Following a PRISMA-aligned protocol, studies published between 2020 and 2025 were screened across Web of Science and Scopus, using predefined eligibility criteria and a two-stage selection process. The resulting evidence was thematically analyzed across three domains: lifecycle and circular-economy-oriented refurbishment strategies; digitalization and predictive maintenance approaches; and environmentally optimized operating regimes. Of the 115 screened records, 37 met the inclusion criteria. Findings indicate that predictive monitoring, data-driven maintenance, and turbine selection tailored to local hydrology can significantly improve energy performance while reducing operation and maintenance costs. The literature also highlights the importance of ecological flow compliance and reduced aquatic impacts. Complementary case studies from Nepal, Switzerland, Germany, Portugal, and Romania illustrate regional challenges and modernization pathways. Overall, the review underscores the need for integrated, multi-objective turbine management that aligns techno-economic, lifecycle, and ecological considerations to support hydropower competitiveness within the energy transition. Full article

Contamination of agricultural water poses significant health risks that are often underrecognized in clinical practice. This review synthesizes peer-reviewed literature from biomedical and environmental sciences. It examines the pathways by which nitrates and zoonotic pathogens contaminate rural drinking water and delineates the resulting spectrum of acute and chronic health risks relevant to primary care. Agricultural practices are a primary source of nitrates and pathogens (e.g., Escherichia coli, Cryptosporidium, Giardia) in rural water supplies. Nitrate nitrogen exposure is linked not only to acute infant methemoglobinemia but also to chronic conditions like colorectal and thyroid cancers and adverse birth outcomes. These risks are observed at concentrations below the current United States Environmental Protection Agency regulatory limit of 10 mg L⁻¹ NO₃⁻–N. Pathogen exposure leads to acute gastrointestinal illness and can trigger long-term sequelae, including irritable bowel syndrome. Agricultural communities are uniquely vulnerable because they rely heavily on unregulated private wells, which are more prone to contamination than public systems. Evidence suggests a substantial and often underrecognized burden of waterborne disease in agricultural communities. The findings highlight a critical need for clinical vigilance regarding low-level nitrate nitrogen exposure and long-term post-infectious syndromes. By identifying these patterns, family physicians serve as essential sentinels for both individual patient safety and community public health. Full article

Land use and land cover (LULC) change strongly influences national carbon dynamics and the effectiveness of forest-based climate mitigation strategies, particularly in mountainous developing countries. This study integrates scenario-based LULC modeling, spatially explicit carbon accounting, and economic valuation to assess how alternative development pathways affect carbon storage and its economic value in Nepal over the 2020–2050 period. LULC projections for four scenarios: Business-as-Usual (BAU), Rapid Urban Development (RUD), Forest Degradation and Terai Contraction (FDTC), and Agricultural Land Abandonment and Ecological Recovery (ALER), were generated using the TerrSet Land Change Modeler, with 2020 as the baseline. These projections were then used as inputs to the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) Carbon Storage and Sequestration model to estimate changes in ecosystem carbon stocks, integrating aboveground biomass, belowground biomass, soil organic carbon, and dead organic matter pools. Carbon stock changes were monetized using a constant carbon price of USD 5/tCO₂e and a 3% discount rate to estimate net present values (NPV). Results reveal strong divergence across scenarios. National carbon storage remains near-neutral under BAU (−0.46% by 2050), declines under RUD (−2.42%) and FDTC (−5.32%), and increases substantially under ALER (+11.74%). These biophysical outcomes translate into contrasting economic values: BAU yields a small negative NPV, RUD and FDTC generate large discounted losses, and ALER produces a strongly positive NPV exceeding USD 800 million by 2050. Spatially, forest and other wooded land dominate national carbon dynamics, while urban expansion and forest degradation drive disproportionate losses. Overall, the study results demonstrate that recovery-oriented land-use pathways offer substantially greater long-term carbon and economic benefits than development trajectories dominated by urban expansion or forest degradation, providing a policy-relevant framework to support Reducing Emissions from Deforestation and Forest Degradation, together with conservation, sustainable forest management, and enhancement of forest carbon stocks (REDD+) planning and long-term mitigation assessment in Nepal. Full article

Under the intensifying impacts of global climate change, high-altitude linear cultural landscapes are increasingly threatened by natural hazards such as extreme precipitation and glacier-fed runoff. Taking the cultural landscape of the Tibet–Nepal Route as the study object, it employs an integrated methodology combining spatial analysis, adaptive assessment, field investigation, and case studies to systematically identify levels of hazard exposure and explore pathways for adaptive governance. This study makes two key contributions. It develops an interdisciplinary framework that combines spatial exposure analysis, barrier diagnosis, and multi-criteria evaluation. It also proposes a governance shift from external interventions to internally driven approaches, underscoring the central role of traditional community institutions system in building landscape resilience. The findings provide a scientific basis for the coordinated governance of cross-border high-altitude linear cultural landscapes between China and Nepal, and offer transferable insights for advancing the World Heritage nomination research of the Silk Road: the routes network of the Qinghai–Tibet Plateau to South Asia Corridor. Full article

Plastic pollution constitutes a critical planetary health challenge, undermining the integrity of Earth systems while generating cascading harms to human health, livelihoods, and social equity particularly in low- and middle-income countries. Conventional top-down regulatory and technological responses have proven insufficient to address the complexity of plastic pollution, often excluding those most affected from decision-making and solution design. This paper examines how democratizing plastic governance through grassroots leadership can advance planetary health by simultaneously protecting ecosystems, improving human well-being, and strengthening socio-ecological resilience. Drawing on empirical evidence from the #RestorationX10000 initiative led by Community Action Against Plastic Waste (CAPws), this paper documents implementation processes and outcomes achieved between 2021 and 2025 across 71 impacted communities in 21 countries spanning Africa, Asia-Pacific, and Latin America. The initiative was designed to empower 10,000 youths and women as community leaders, practitioners, and advocates by equipping them with leadership, technical, and policy engagement skills to drive systemic change in plastic governance and circular economy practice. Using a transdisciplinary, community-based action research approach aligned with planetary health principles, the initiative integrates capacity building, citizen science, circular economy interventions (collection, sorting, repair, reuse, repurposing, and recycling), and policy advocacy. Quantitative and qualitative evidence demonstrates that grassroots-led interventions can simultaneously reduce plastic leakage, create decent green livelihoods, and strengthen environmental governance. We argue that inclusive, community-centered plastic governance is not only an environmental intervention but a planetary health strategy, offering policy-relevant insights for national plastic action plans, extended producer responsibility frameworks, and global negotiations toward a legally binding instrument on plastic pollution. Full article

Moringa oleifera (Lam.) is a multipurpose agroforestry tree cultivated worldwide for its nutritional, medicinal, and economic value, and it is increasingly grown commercially in subtropical regions, including Nepal. While vegetative propagation is feasible, large-scale production relies predominantly on seeds, making efficient germination critical for seedling establishment, uniform growth, sustainable production, and preservation of genetic diversity. Seed pre-treatments are widely recognized as a simple and effective approach to enhance germination, early seedling vigor, and nursery performance. This study evaluated the effects of seven pre-sowing treatments under controlled nursery conditions to determine the most effective method for improving Moringa oleifera seedling production. A total of 2100 seeds were used, with 100 seeds per treatment and three replicates, arranged in a Completely Randomized Design (CRD). Treatments included control (no pretreatment), normal water soaking (12 h and 24 h), alternating wetting (water) and drying cycles (12 h each), hot water soaking (60 °C for 5 min), cow urine soaking (1:2 of urine to water proportions for 12 h), and hydrochloric acid soaking (35% for 20 min). All pre-treatments were conducted at room temperature, and the seeds were subsequently sown in controlled nursery conditions. Seed germination was monitored twice daily for 30 days, and data were analyzed using one-way ANOVA and Tukey’s HSD test to identify significant differences in germination performances. Results demonstrated that alternating wetting and drying produced the highest germination percentage (89%), shortest mean germination time (8.44 days), and strongest seedling vigor, outperforming all other treatments. Conversely, cow urine and acid treatments completely inhibited germination. This study recommends alternating wetting and drying as a simple, low-cost, and chemical-free pre-treatment to optimize Moringa oleifera seedling production in nurseries. These findings provide practical guidance for commercial and smallholder farmers, contributing to sustainable agroforestry, food security, and climate-resilient livelihoods in resource-limited habitats. Full article

Background and Clinical Significance: Congenital erythropoietic porphyria (CEP), also known as Günther disease, is a rare autosomal recessive porphyria caused by a deficiency of uroporphyrinogen III synthase, leading to the accumulation of phototoxic type I porphyrins. CEP classically presents in infancy with severe photosensitivity, blistering, scarring, and hemolytic anemia; however, significant phenotypic variability has increasingly been recognized. Case Presentation: We report a 32-year-old woman diagnosed with CEP in early infancy who demonstrated persistently and profoundly elevated erythrocyte porphyrin levels over more than a decade, yet who followed a relatively non-mutilating clinical course. Genetic testing identified a low-penetrance intronic UROS variant typically associated with erythropoietic protoporphyria, underscoring diagnostic challenges and genotype–phenotype discordance. The patient experienced marked improvement in photosensitivity and burning pain after initiation of afamelanotide, without the need for transfusion therapy or stem cell transplantation. Conclusions: This case highlights the heterogeneity of CEP, the importance of long-term biochemical follow up, and the potential role of afamelanotide in improving quality of life for selected patients with CEP. Full article

A dam breach is an uncommon but profoundly destructive event that transpires when a dam collapses, releasing accumulated water downstream and leading to extensive damage. This study focuses on the Jure landslide dam, located in the Sindhupalchowk district, Nepal. The region is characterized by complex river channels and steep terrains, which are significantly influenced by flood dynamics. This study aims to establish a compressive numerical simulation of a two-dimensional dam breach unsteady flow hydraulic model to simulate the dam breach process and downstream flood propagation. The study analyzes the dynamics of the Jure landslide dam outburst flood, emphasizing the flood characteristics, inundation, and velocity hazards in the mitigation of flood impacts. The results reveal that the peak discharge of the Jure landside dam was 5336.7 m³/s, while it decreased to 1181.4 m³/s when traveling 35 km. The flood depth obtained by 2D (HEC-RAS) downstream of the dam rages between 0.0334 and 55.9 m, while the corresponding estimated peak flow velocity of simulated breaches was 21.46 m/s, demonstrating extreme hydraulic force conditions, capable of catastrophe. The proposed hydraulic simulations reveal significant variations in overflow dynamics across different terrain types, with narrower sections exhibiting faster flood progression and greater water depths. The findings underscore the necessity of accounting for terrain heterogeneity in future flood risk assessments. This work offers valuable insights into the emergency management of landslide dams in similar regions. Full article

Buckwheat (Fagopyrum esculentum) is an important source of nutrition for humans, providing essential nutrients such as protein, fiber, vitamins, and minerals. Its cultivation is highly attractive to flower-visiting insects, which find abundant nectar and a moderate amount of pollen grains. This study aimed to characterize the taxonomic diversity and composition of flower-visiting insect communities in buckwheat crops across two sites in Chitwan district, Nepal and to assess whether temperature and relative humidity influence community structure. We further quantified the contribution of insect pollination to buckwheat yield by comparing pollinator-excluded plots (net-covered) with open-pollinated plots. In addition, we estimated the economic value of insect-mediated pollination and the nutritional contribution of buckwheat production on a per capita basis. Data were analyzed using non-metric multidimensional scaling, permutational multivariate analysis of variance, similarity percentage analysis, and (generalized) linear mixed-effects models. We found significant differences in flower-visiting insect community composition between the two study sites, independent of temperature and relative humidity, with twelve taxa contributing most to this dissimilarity. Open-pollinated plots exhibited higher buckwheat yields than pollinator-excluded plots, highlighting the importance of insect visitation for crop production. Despite the presence of managed Apis species, we recorded frequent visitation by flies and solitary bees, indicating that these taxa are likely important contributors to buckwheat pollination at local scales. Similarly, insect-mediated pollination significantly increased buckwheat production, and its absence would result in substantial economic losses of USD 2.6 million and reduced nutritional contributions, highlighting the vulnerability of buckwheat-based food security for the Nepalese communities due to pollinator decline. Full article