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  • Article
  • Open Access
3 Citations
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25 Pages

Benchmarking of Approaches for Gene Copy-Number Variation Analysis and Its Utility for Genetic Aberration Detection in High-Grade Serous Ovarian Carcinomas

  • Pavel Alekseevich Grebnev,
  • Ivan Olegovich Meshkov,
  • Pavel Viktorovich Ershov,
  • Antonida Viktorovna Makhotenko,
  • Valentina Bogdanovna Azarian,
  • Marina Vyacheslavovna Erokhina,
  • Anastasiya Aleksandrovna Galeta,
  • Aleksandr Vladimirovich Zakubanskiy,
  • Olga Sergeevna Shingalieva and
  • Veronika Igorevna Skvortsova
  • + 8 authors

24 September 2024

Objective: The goal of this study was to compare the results of CNV detection by three different methods using 13 paired carcinoma samples, as well as to perform a statistical analysis of the agreement. Methods: CNV was studied using NanoString nCoun...