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Keywords = Markov logic networks

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20 pages, 358 KB  
Article
Ideal (I2) Convergence in Fuzzy Paranormed Spaces for Practical Stability of Discrete-Time Fuzzy Control Systems Under Lacunary Measurements
by Muhammed Recai Türkmen and Hasan Öğünmez
Axioms 2025, 14(9), 663; https://doi.org/10.3390/axioms14090663 - 29 Aug 2025
Viewed by 505
Abstract
We investigate the stability of linear discrete-time control systems with a fuzzy logic feedback under sporadic sensor data loss. In our framework, each state measurement is a fuzzy number, and occasional “packet dropouts” are modeled by a lacunary subsequence of missing readings. We [...] Read more.
We investigate the stability of linear discrete-time control systems with a fuzzy logic feedback under sporadic sensor data loss. In our framework, each state measurement is a fuzzy number, and occasional “packet dropouts” are modeled by a lacunary subsequence of missing readings. We introduce a novel mathematical approach using lacunary statistical convergence in fuzzy paranormed spaces to analyze such systems. Specifically, we treat the sequence of fuzzy measurements as a double sequence (indexed by time and state component) and consider an admissible ideal of “negligible” index sets that includes the missing–data pattern. Using the concept of ideal fuzzy—paranorm convergence (I-fp convergence), we formalize a lacunary statistical consistency condition on the fuzzy measurements. We prove that if the closed-loop matrix ABK is Schur stable (i.e., ABK<1) in the absence of dropouts, then under the lacunary statistical consistency condition, the controlled system is practically stable despite intermittent measurement losses. In other words, for any desired tolerance, the state eventually remains within that bound (though not necessarily converging to zero). Our result yields an explicit, non-probabilistic (distribution-free) analytical criterion for robustness to sensor dropouts, without requiring packet-loss probabilities or Markov transition parameters. This work merges abstract convergence theory with control application: it extends statistical and ideal convergence to double sequences in fuzzy normed spaces and applies it to ensure stability of a networked fuzzy control system. Full article
(This article belongs to the Special Issue Mathematical Modeling and Control: Theory and Applications)
38 pages, 6012 KB  
Article
Adaptive Spectrum Management in Optical WSNs for Real-Time Data Transmission and Fault Tolerance
by Mohammed Alwakeel
Mathematics 2025, 13(17), 2715; https://doi.org/10.3390/math13172715 - 23 Aug 2025
Viewed by 527
Abstract
Optical wireless sensor networks (OWSNs) offer promising capabilities for high-speed, energy-efficient communication, particularly in mission-critical environments such as industrial automation, healthcare monitoring, and smart buildings. However, dynamic spectrum management and fault tolerance remain key challenges in ensuring reliable and timely data transmission. This [...] Read more.
Optical wireless sensor networks (OWSNs) offer promising capabilities for high-speed, energy-efficient communication, particularly in mission-critical environments such as industrial automation, healthcare monitoring, and smart buildings. However, dynamic spectrum management and fault tolerance remain key challenges in ensuring reliable and timely data transmission. This paper proposes an adaptive spectrum management framework (ASMF) that addresses these challenges through a mathematically grounded and implementation-driven approach. The ASMF formulates the spectrum allocation problem as a constrained Markov decision process and leverages a dual-layer optimization strategy combining Lyapunov drift-plus-penalty for queue stability with deep reinforcement learning for adaptive long-term decision making. Additionally, ASMF integrates a hybrid fault-tolerant mechanism using LSTM-based link failure prediction and lightweight recovery logic, achieving up to 83% prediction accuracy. Experimental evaluations using real-world datasets from industrial, healthcare, and smart infrastructure scenarios demonstrate that ASMF reduces critical traffic latency by 37%, improves reliability by 42% under fault conditions, and enhances energy efficiency by 22.6% compared with state-of-the-art methods. The system also maintains a 99.94% packet delivery ratio for critical traffic and achieves 69.7% faster recovery after link failures. These results confirm the effectiveness of ASMF as a robust and scalable solution for adaptive spectrum management in dynamic, fault-prone OWSN environments. Full article
(This article belongs to the Special Issue Advances in Mobile Network and Intelligent Communication)
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20 pages, 669 KB  
Article
An Inference Framework of Markov Logic Network for Link Prediction in Heterogeneous Networks
by Zhongbin Li, Kun Yue, Lixing Yu and Jiahui Wang
Appl. Sci. 2025, 15(8), 4424; https://doi.org/10.3390/app15084424 - 17 Apr 2025
Viewed by 534
Abstract
The presence of multiplex edges and sparse links often hampers the efficacy of link prediction (LP) tasks. By harnessing the expressive power of Markov logic network (MLN) formulations, multiplex edges can be unified to enhance LP effectiveness. However, scaling up inferences for effective [...] Read more.
The presence of multiplex edges and sparse links often hampers the efficacy of link prediction (LP) tasks. By harnessing the expressive power of Markov logic network (MLN) formulations, multiplex edges can be unified to enhance LP effectiveness. However, scaling up inferences for effective LP remains challenging due to the inefficiency of traditional MLN inference methods. To tackle this issue, we redefine LP tasks within heterogeneous networks using MLN inferences and introduce a tailored inference framework to handle unobserved nodes and complex MLN structures. We propose a method to partition the MLN structure into discrete substructures and compute node label distributions using the variational expectation maximization (VEM) algorithm. Additionally, we establish a termination condition to streamline inference search space and present the MLN-based LP algorithm. Experimental findings demonstrate the efficacy of our VEM-driven MLN inference framework for LP tasks in heterogeneous networks, showcasing superior accuracy compared to existing approaches. Full article
(This article belongs to the Special Issue Innovative Data Mining Techniques for Advanced Recommender Systems)
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21 pages, 6998 KB  
Article
Spatiotemporal Prediction of the Impact of Dynamic Passenger Flow at Subway Stations on the Sustainable Industrial Heritage Land Use
by Ke Chen, Fei Fu, Fangzhou Tian, Liwei Lin and Can Du
Sustainability 2025, 17(8), 3544; https://doi.org/10.3390/su17083544 - 15 Apr 2025
Cited by 1 | Viewed by 638
Abstract
Inefficient land reuse has emerged as a critical pathway for the sustainable development of urban spaces. Efficient land development in megacities’ industrial heritage areas is heavily influenced by the influx of mass passenger flows from new subway stations. To address this issue, a [...] Read more.
Inefficient land reuse has emerged as a critical pathway for the sustainable development of urban spaces. Efficient land development in megacities’ industrial heritage areas is heavily influenced by the influx of mass passenger flows from new subway stations. To address this issue, a dynamic passenger flow-oriented land use prediction model for subway stations was developed. This model iterates a simulation model for dynamic passenger flow based on tourists and residents with an artificial neural network for land use prediction. By enhancing the kappa coefficient to 0.86, the model accurately simulated pedestrian flow density from stations to streets. Experiments were conducted to predict inefficient land use scenarios, which were then compared with the current state in national industrial heritage areas. The results demonstrated that the AnyLogic-Markov-FLUS Coupled Model outperformed expert experience in objectively assessing dynamic passenger flow impacts on the carrying capacity of old city neighborhoods during peak and off-peak periods at subway stations. This model can assist in resilient urban space planning and decision-making regarding mixed land use. Full article
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20 pages, 1923 KB  
Article
PRG4CNN: A Probabilistic Model Checking-Driven Robustness Guarantee Framework for CNNs
by Yang Liu and Aohui Fang
Entropy 2025, 27(2), 163; https://doi.org/10.3390/e27020163 - 3 Feb 2025
Viewed by 1302
Abstract
As an important kind of DNN (deep neural network), CNN (convolutional neural network) has made remarkable progress and been widely used in the vision and decision-making of autonomous robots. Nonetheless, in many scenarios, even a minor perturbation in input for CNNs may lead [...] Read more.
As an important kind of DNN (deep neural network), CNN (convolutional neural network) has made remarkable progress and been widely used in the vision and decision-making of autonomous robots. Nonetheless, in many scenarios, even a minor perturbation in input for CNNs may lead to serious errors, which means CNNs lack robustness. Formal verification is an effective method to guarantee the robustness of CNNs. Existing works predominantly concentrate on local robustness verification, which requires considerable time and space. Probabilistic robustness quantifies the robustness of CNNs, which is a practical mode of potential measurement. The state-of-the-art of probabilistic robustness verification is a test-driven approach, which is used to manually decide whether a DNN satisfies the probabilistic robustness and does not involve robustness repair. Robustness repair can improve the robustness of CNNs further. To address this issue, we propose a probabilistic model checking-driven robustness guarantee framework for CNNs, i.e., PRG4CNN. This is the first automated and complete framework for guaranteeing the probabilistic robustness of CNNs. It comprises four steps, as follows: (1) modeling a CNN as an MDP (Markov decision processes) by model learning, (2) specifying the probabilistic robustness of the CNN via the PCTL (Probabilistic Computational Tree Logic) formula, (3) verifying the probabilistic robustness with a probabilistic model checker, and (4) probabilistic robustness repair by counterexample-guided sensitivity analysis, if probabilistic robustness does not hold on the CNN. We here conduct experiments on various scales of CNNs trained on the handwriting dataset MNIST, and demonstrate the effectiveness of PRG4CNN. Full article
(This article belongs to the Special Issue Information-Theoretic Methods for Trustworthy Machine Learning)
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34 pages, 2406 KB  
Article
Security Control for a Fuzzy System under Dynamic Protocols and Cyber-Attacks with Engineering Applications
by Mourad Kchaou, Cecilia Castro, Rabeh Abbassi, Víctor Leiva and Houssem Jerbi
Mathematics 2024, 12(13), 2112; https://doi.org/10.3390/math12132112 - 5 Jul 2024
Cited by 4 | Viewed by 1523
Abstract
The objective of this study is to design a security control for ensuring the stability of systems, maintaining their state within bounded limits and securing operations. Thus, we enhance the reliability and resilience in control systems for critical infrastructure such as manufacturing, network [...] Read more.
The objective of this study is to design a security control for ensuring the stability of systems, maintaining their state within bounded limits and securing operations. Thus, we enhance the reliability and resilience in control systems for critical infrastructure such as manufacturing, network bandwidth constraints, power grids, and transportation amid increasing cyber-threats. These systems operate as singularly perturbed structures with variables changing at different time scales, leading to complexities such as stiffness and parasitic parameters. To manage these complexities, we integrate type-2 fuzzy logic with Markov jumps in dynamic event-triggered protocols. These protocols handle communications, optimizing network resources and improving security by adjusting triggering thresholds in real-time based on system operational states. Incorporating fractional calculus into control algorithms enhances the modeling of memory properties in physical systems. Numerical studies validate the effectiveness of our proposal, demonstrating a 20% reduction in network load and enhanced stochastic stability under varying conditions and cyber-threats. This innovative proposal enables real-time adaptation to changing conditions and robust handling of uncertainties, setting it apart from traditional control strategies by offering a higher level of reliability and resilience. Our methodology shows potential for broader application in improving critical infrastructure systems. Full article
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34 pages, 659 KB  
Article
Two-Stage Limited-Information Estimation for Structural Equation Models of Round-Robin Variables
by Terrence D. Jorgensen, Aditi M. Bhangale and Yves Rosseel
Stats 2024, 7(1), 235-268; https://doi.org/10.3390/stats7010015 - 28 Feb 2024
Cited by 2 | Viewed by 2900
Abstract
We propose and demonstrate a new two-stage maximum likelihood estimator for parameters of a social relations structural equation model (SR-SEM) using estimated summary statistics (Σ^) as data, as well as uncertainty about Σ^ to obtain robust inferential statistics. The [...] Read more.
We propose and demonstrate a new two-stage maximum likelihood estimator for parameters of a social relations structural equation model (SR-SEM) using estimated summary statistics (Σ^) as data, as well as uncertainty about Σ^ to obtain robust inferential statistics. The SR-SEM is a generalization of a traditional SEM for round-robin data, which have a dyadic network structure (i.e., each group member responds to or interacts with each other member). Our two-stage estimator is developed using similar logic as previous two-stage estimators for SEM, developed for application to multilevel data and multiple imputations of missing data. We demonstrate out estimator on a publicly available data set from a 2018 publication about social mimicry. We employ Markov chain Monte Carlo estimation of Σ^ in Stage 1, implemented using the R package rstan. In Stage 2, the posterior mean estimates of Σ^ are used as input data to estimate SEM parameters with the R package lavaan. The posterior covariance matrix of estimated Σ^ is also calculated so that lavaan can use it to calculate robust standard errors and test statistics. Results are compared to full-information maximum likelihood (FIML) estimation of SR-SEM parameters using the R package srm. We discuss how differences between estimators highlight the need for future research to establish best practices under realistic conditions (e.g., how to specify empirical Bayes priors in Stage 1), as well as extensions that would make 2-stage estimation particularly advantageous over single-stage FIML. Full article
(This article belongs to the Section Statistical Methods)
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23 pages, 1647 KB  
Article
Controllable Queuing System with Elastic Traffic and Signals for Resource Capacity Planning in 5G Network Slicing
by Irina Kochetkova, Kseniia Leonteva, Ibram Ghebrial, Anastasiya Vlaskina, Sofia Burtseva, Anna Kushchazli and Konstantin Samouylov
Future Internet 2024, 16(1), 18; https://doi.org/10.3390/fi16010018 - 31 Dec 2023
Cited by 1 | Viewed by 3082
Abstract
Fifth-generation (5G) networks provide network slicing capabilities, enabling the deployment of multiple logically isolated network slices on a single infrastructure platform to meet specific requirements of users. This paper focuses on modeling and analyzing resource capacity planning and reallocation for network slicing, specifically [...] Read more.
Fifth-generation (5G) networks provide network slicing capabilities, enabling the deployment of multiple logically isolated network slices on a single infrastructure platform to meet specific requirements of users. This paper focuses on modeling and analyzing resource capacity planning and reallocation for network slicing, specifically between two providers transmitting elastic traffic, such during as web browsing. A controller determines the need for resource reallocation and plans new resource capacity accordingly. A Markov decision process is employed in a controllable queuing system to find the optimal resource capacity for each provider. The reward function incorporates three network slicing principles: maximum matching for equal resource partitioning, maximum share of signals resulting in resource reallocation, and maximum resource utilization. To efficiently compute the optimal resource capacity planning policy, we developed an iterative algorithm that begins with maximum resource utilization as the starting point. Through numerical demonstrations, we show the optimal policy and metrics of resource reallocation for two services: web browsing and bulk data transfer. The results highlight fast convergence within three iterations and the effectiveness of the balanced three-principle approach in resource capacity planning for 5G network slicing. Full article
(This article belongs to the Special Issue Performance and QoS Issues of 5G Wireless Networks and Beyond)
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20 pages, 6061 KB  
Article
The Markov Concept of the Energy Efficiency Assessment of the Edge Computing Infrastructure Peripheral Server Functioning over Time
by Viacheslav Kovtun, Torki Altameem, Mohammed Al-Maitah and Wojciech Kempa
Electronics 2023, 12(20), 4320; https://doi.org/10.3390/electronics12204320 - 18 Oct 2023
Cited by 4 | Viewed by 1320
Abstract
The article is devoted to the research of the peripheral server energy consumption managing process defined based on the threshold policy by manipulating the values of the characteristic parameters of the arithmetic-logical complex of the latter. The research object is formalized by a [...] Read more.
The article is devoted to the research of the peripheral server energy consumption managing process defined based on the threshold policy by manipulating the values of the characteristic parameters of the arithmetic-logical complex of the latter. The research object is formalized by a Markov queue model with a single-threshold control scheme for the intensity of accepted requests service. A characteristic feature of the life cycle of a peripheral server is the non-stationary mode of operation in terms of energy consumption, due to the need to periodically poll the controlled sensor network and process the received data in real-time. To take into account this circumstance, the intensities of transitions in the heterogeneous birth-and-death Markov process of the created model are interpreted as non-random periodic functions of time. The resulting mathematical apparatus is summarized in the metric that allows us to estimate the target peripheral server’s energy consumption both at a specific moment and for a censored time interval (this distinguishes the obtained result from existing analogs). Full article
(This article belongs to the Section Computer Science & Engineering)
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23 pages, 888 KB  
Article
A Meta Reinforcement Learning Approach for SFC Placement in Dynamic IoT-MEC Networks
by Shuang Guo, Yarong Du and Liang Liu
Appl. Sci. 2023, 13(17), 9960; https://doi.org/10.3390/app13179960 - 3 Sep 2023
Cited by 5 | Viewed by 2446
Abstract
In order to achieve reliability, security, and scalability, the request flow in the Internet of Things (IoT) needs to pass through the service function chain (SFC), which is composed of series-ordered virtual network functions (VNFs), then reach the destination application in multiaccess edge [...] Read more.
In order to achieve reliability, security, and scalability, the request flow in the Internet of Things (IoT) needs to pass through the service function chain (SFC), which is composed of series-ordered virtual network functions (VNFs), then reach the destination application in multiaccess edge computing (MEC) for processing. Since there are usually multiple identical VNF instances in the network and the network environment of IoT changes dynamically, placing the SFC for the IoT request flow is a significant challenge. This paper decomposes the dynamic SFC placement problem of the IoT-MEC network into two subproblems: VNF placement and path determination of routing. We first formulate these two subproblems as Markov decision processes. We then propose a meta reinforcement learning and fuzzy logic-based dynamic SFC placement approach (MRLF-SFCP). The MRLF-SFCP contains an inner model that focuses on making SFC placement decisions and an outer model that focuses on learning the initial parameters considering the dynamic IoT-MEC environment. Specifically, the approach uses fuzzy logic to pre-evaluate the link status information of the network by jointly considering available bandwidth, delay, and packet loss rate, which is helpful for model training and convergence. In comparison to existing algorithms, simulation results demonstrate that the MRLF-SFCP algorithm exhibits superior performance in terms of traffic acceptance rate, throughput, and the average reward. Full article
(This article belongs to the Special Issue Advanced Artificial Intelligence Theories and Applications)
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20 pages, 741 KB  
Article
Teaching Probabilistic Graphical Models with OpenMarkov
by Francisco Javier Díez, Manuel Arias, Jorge Pérez-Martín and Manuel Luque
Mathematics 2022, 10(19), 3577; https://doi.org/10.3390/math10193577 - 30 Sep 2022
Cited by 4 | Viewed by 2571
Abstract
OpenMarkov is an open-source software tool for probabilistic graphical models. It has been developed especially for medicine, but has also been used to build applications in other fields and for tuition, in more than 30 countries. In this paper we explain how to [...] Read more.
OpenMarkov is an open-source software tool for probabilistic graphical models. It has been developed especially for medicine, but has also been used to build applications in other fields and for tuition, in more than 30 countries. In this paper we explain how to use it as a pedagogical tool to teach the main concepts of Bayesian networks and influence diagrams, such as conditional dependence and independence, d-separation, Markov blankets, explaining away, optimal policies, expected utilities, etc., and some inference algorithms: logic sampling, likelihood weighting, and arc reversal. The facilities for learning Bayesian networks interactively can be used to illustrate step by step the performance of the two basic algorithms: search-and-score and PC. Full article
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17 pages, 2812 KB  
Article
Dynamic Scheduling of Crane by Embedding Deep Reinforcement Learning into a Digital Twin Framework
by Zhenyu Xu, Daofang Chang, Miaomiao Sun and Tian Luo
Information 2022, 13(6), 286; https://doi.org/10.3390/info13060286 - 4 Jun 2022
Cited by 11 | Viewed by 4089
Abstract
This study proposes a digital twin (DT) application framework that integrates deep reinforcement learning (DRL) algorithms for the dynamic scheduling of crane transportation in workshops. DT is used to construct the connection between the workshop service system, logical simulation environment, 3D visualization model [...] Read more.
This study proposes a digital twin (DT) application framework that integrates deep reinforcement learning (DRL) algorithms for the dynamic scheduling of crane transportation in workshops. DT is used to construct the connection between the workshop service system, logical simulation environment, 3D visualization model and physical workshop, and DRL is used to support the core decision in scheduling. First, the dynamic scheduling problem of crane transportation is constructed as a Markov decision process (MDP), and the corresponding double deep Q-network (DDQN) is designed to interact with the logic simulation environment to complete the offline training of the algorithm. Second, the trained DDQN is embedded into the DT framework, and then connected with the physical workshop and the workshop service system to realize online dynamic crane scheduling based on the real-time states of the workshop. Finally, case studies of crane scheduling under dynamic job arrival and equipment failure scenarios are presented to demonstrate the effectiveness of the proposed framework. The numerical analysis shows that the proposed method is superior to the traditional dynamic scheduling method, and it is also suitable for large-scale problems. Full article
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54 pages, 1710 KB  
Review
A Systematic Literature Review of Cutting Tool Wear Monitoring in Turning by Using Artificial Intelligence Techniques
by Lorenzo Colantonio, Lucas Equeter, Pierre Dehombreux and François Ducobu
Machines 2021, 9(12), 351; https://doi.org/10.3390/machines9120351 - 10 Dec 2021
Cited by 58 | Viewed by 10381
Abstract
In turning operations, the wear of cutting tools is inevitable. As workpieces produced with worn tools may fail to meet specifications, the machining industries focus on replacement policies that mitigate the risk of losses due to scrap. Several strategies, from empiric laws to [...] Read more.
In turning operations, the wear of cutting tools is inevitable. As workpieces produced with worn tools may fail to meet specifications, the machining industries focus on replacement policies that mitigate the risk of losses due to scrap. Several strategies, from empiric laws to more advanced statistical models, have been proposed in the literature. More recently, many monitoring systems based on Artificial Intelligence (AI) techniques have been developed. Due to the scope of different artificial intelligence approaches, having a holistic view of the state of the art on this subject is complex, in part due to a lack of recent comprehensive reviews. This literature review therefore presents 20 years of literature on this subject obtained following a Systematic Literature Review (SLR) methodology. This SLR aims to answer the following research question: “How is the AI used in the framework of monitoring/predicting the condition of tools in stable turning condition?” To answer this research question, the “Scopus” database was consulted in order to gather relevant publications published between 1 January 2000 and 1 January 2021. The systematic approach yielded 8426 articles among which 102 correspond to the inclusion and exclusion criteria which limit the application of AI to stable turning operation and online prediction. A bibliometric analysis performed on these articles highlighted the growing interest of this subject in the recent years. A more in-depth analysis of the articles is also presented, mainly focusing on six AI techniques that are highly represented in the literature: Artificial Neural Network (ANN), fuzzy logic, Support Vector Machine (SVM), Self-Organizing Map (SOM), Hidden Markov Model (HMM), and Convolutional Neural Network (CNN). For each technique, the trends in the inputs, pre-processing techniques, and outputs of the AI are presented. The trends highlight the early and continuous importance of ANN, and the emerging interest of CNN for tool condition monitoring. The lack of common benchmark database for evaluating models performance does not allow clear comparisons of technique performance. Full article
(This article belongs to the Special Issue Advances in Tool Life Prediction in Machining)
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18 pages, 12579 KB  
Article
Algorithm for Preventing the Spread of COVID-19 in Airports and Air Routes by Applying Fuzzy Logic and a Markov Chain
by Cesar Guevara and Diego Bonilla
Mathematics 2021, 9(23), 3040; https://doi.org/10.3390/math9233040 - 26 Nov 2021
Cited by 5 | Viewed by 3319
Abstract
Since the start of COVID-19 and its growth into an uncontrollable pandemic, the spread of diseases through airports has become a serious health problem around the world. This study presents an algorithm to determine the risk of spread in airports and air routes. [...] Read more.
Since the start of COVID-19 and its growth into an uncontrollable pandemic, the spread of diseases through airports has become a serious health problem around the world. This study presents an algorithm to determine the risk of spread in airports and air routes. Graphs are applied to model the air transport network and Dijkstra’s algorithm is used for generating routes. Fuzzy logic is applied to evaluate multiple demographics, health, and transport variables and identify the level of spread in each airport. The algorithm applies a Markov chain to determine the probability of the arrival of an infected passenger with the COVID-19 virus to an airport in any country in the world. The results show the optimal performance of the proposed algorithm. In addition, some data are presented that allow for the application of actions in health and mobility policies to prevent the spread of infectious diseases. Full article
(This article belongs to the Special Issue Advanced Aspects of Computational Intelligence with Its Applications)
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17 pages, 4631 KB  
Article
Gene Network Analysis of Alzheimer’s Disease Based on Network and Statistical Methods
by Chen Zhou, Haiyan Guo and Shujuan Cao
Entropy 2021, 23(10), 1365; https://doi.org/10.3390/e23101365 - 19 Oct 2021
Cited by 5 | Viewed by 2945
Abstract
Gene network associated with Alzheimer’s disease (AD) is constructed from multiple data sources by considering gene co-expression and other factors. The AD gene network is divided into modules by Cluster one, Markov Clustering (MCL), Community Clustering (Glay) and Molecular Complex Detection (MCODE). Then [...] Read more.
Gene network associated with Alzheimer’s disease (AD) is constructed from multiple data sources by considering gene co-expression and other factors. The AD gene network is divided into modules by Cluster one, Markov Clustering (MCL), Community Clustering (Glay) and Molecular Complex Detection (MCODE). Then these division methods are evaluated by network structure entropy, and optimal division method, MCODE. Through functional enrichment analysis, the functional module is identified. Furthermore, we use network topology properties to predict essential genes. In addition, the logical regression algorithm under Bayesian framework is used to predict essential genes of AD. Based on network pharmacology, four kinds of AD’s herb-active compounds-active compound targets network and AD common core network are visualized, then the better herbs and herb compounds of AD are selected through enrichment analysis. Full article
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