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Search Results (231)

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Keywords = MARS3D

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12 pages, 3201 KB  
Article
Reliability of Prediction Models for the Functional Classification of a Sinusoidal Intraocular Lens Depending on Pupil Diameter
by Diego Montagud-Martínez, Walter D. Furlan, Vicente Ferrando, Manuel Rodríguez-Vallejo and Joaquín Fernández
Diagnostics 2025, 15(19), 2446; https://doi.org/10.3390/diagnostics15192446 - 25 Sep 2025
Abstract
Background: To assess the agreement among prediction models for the functional classification of intraocular lenses (IOLs) and discuss their limitations in evaluating pupil dependency of a sinusoidal IOL. Methods: An ISO-compliant optical bench setup with modifications to characterize the modulation transfer function area [...] Read more.
Background: To assess the agreement among prediction models for the functional classification of intraocular lenses (IOLs) and discuss their limitations in evaluating pupil dependency of a sinusoidal IOL. Methods: An ISO-compliant optical bench setup with modifications to characterize the modulation transfer function area (MTFa) across pupil diameters from 1.5 to 5.5 mm was used to measure the Acriva Trinova Pro C Pupil Adaptive IOL. Six prediction models (Vega et al., 2018, Fernández et al., 2019, Alarcón et al., 2016, Armengol et al., 2020 were applied to estimate visual acuity defocus curves from MTFa and functional classification based on the depth-of-field (DOFi) and the increase in visual acuity (ΔVA) from intermediate to near. Results: Defocus curves for all prediction models consistently demonstrated a Full-DOFi response (>2.3 D at 0.2 logMAR), with differences in ΔVA emerging across pupil diameters. Continuous decreases (ΔVA < 0.05 logMAR) were observed at pupil diameters <2.5 mm, while Smooth transitions (ΔVA from 0.05 to 0.14 logMAR) occurred between 2.5–3.0 mm for all models except for Vega. At pupil diameters >3.5 mm, most models transitioned to a Steep classification (ΔVA ≥ 0.14 logMAR), except Fernández, which remained Smooth, and Armengol 2020a, which shifted to Steep at 4.0 mm. Conclusions: Visual acuity prediction models provide useful means of reporting optical bench data in clinically familiar metrics. However, outcomes should be interpreted with caution as functional classifications can vary depending on the optical bench setup and prediction model used. Full article
(This article belongs to the Special Issue Diagnosing, Treating, and Preventing Eye Diseases)
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13 pages, 4670 KB  
Technical Note
Restoration of Motion-Blurred, High-Resolution Mars Express SRC Images of Phobos
by Ryodo Hemmi and Hiroshi Kikuchi
Remote Sens. 2025, 17(18), 3256; https://doi.org/10.3390/rs17183256 - 21 Sep 2025
Viewed by 219
Abstract
We present an automated and fully reproducible pipeline for restoring motion-smeared Mars Express SRC images of Phobos. A one-dimensional motion point spread function (PSF) is derived directly from SPICE geometry and microsecond-precision exposure timing, and Wiener deconvolution (SNR = 16 dB) is applied [...] Read more.
We present an automated and fully reproducible pipeline for restoring motion-smeared Mars Express SRC images of Phobos. A one-dimensional motion point spread function (PSF) is derived directly from SPICE geometry and microsecond-precision exposure timing, and Wiener deconvolution (SNR = 16 dB) is applied to recover image sharpness. Tested on 14 images from 4 orbits spanning slant distances of 52–292 km, exposures of 14–20 milliseconds, sampling of 0.47–2.7 m/pixel, and PSF lengths of 11–119 pixels, the method achieves up to 31.7 dB PSNR, 0.78 SSIM, and positive sharpness gains across all cases. The restored images reveal sub-meter surface features previously obscured by motion blur, with residual energy reduced relative to the acquisition model. The workflow relies solely on open data and open-source tools (ISIS, ALE/SpiceyPy, OpenCV), requires no star-field calibration, and generalizes to other motion-degraded planetary datasets, providing a fully transparent and reproducible solution for high-resolution planetary imaging. Full article
(This article belongs to the Section Satellite Missions for Earth and Planetary Exploration)
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9 pages, 1409 KB  
Case Report
Presbyopia-Correcting Intraocular Lens with Butterfly-Shaped Central Area Implanted in a Large Angle Kappa Patient: A Case Report
by Camille Bosc, Sandra Delaunay, Anne Barrucand and Irene Martínez-Alberquilla
J. Clin. Transl. Ophthalmol. 2025, 3(3), 18; https://doi.org/10.3390/jcto3030018 - 11 Sep 2025
Viewed by 306
Abstract
Background: Intraocular lens (IOL) alignment is crucial for optimal performance in presbyopia-correcting designs. The aim was to report a case of a patient with a high angle kappa implanted with the continuous transitional focus (CTF) Precizon Prebyopic NVA IOL. Case presentation: A 51-year-old [...] Read more.
Background: Intraocular lens (IOL) alignment is crucial for optimal performance in presbyopia-correcting designs. The aim was to report a case of a patient with a high angle kappa implanted with the continuous transitional focus (CTF) Precizon Prebyopic NVA IOL. Case presentation: A 51-year-old patient presenting large angle kappa values (0.6/0.8 mm) was implanted with the Precizon Prebyopic NVA IOL and followed-up 1 and 10 months post-surgery. This IOL is designed with a butterfly-shaped central area that allows the orientation of the lens so that the visual axis passes through the wider diameter of the optic zone. Postoperative refraction was −0.25D of cyl at 80° for the right eye and +0.25D −0.50D cyl at 170°. Corrected distance visual acuity (CDVA) at the last visit was −0.1 logMAR monocularly and −0.2 logMAR binocularly. Binocular uncorrected distance (UDVA), intermediate (UIVA) and near visual acuities (UNVA) were −0.1, 0.1 and 0.1 logMAR, respectively. The corrected binocular defocus curve exhibited outstanding vision at the 0.00D defocus level and showed a continuous range of functional vision from distance to near. Overall excellent satisfaction was reported, along with low levels of photopic phenomena. Conclusions: Precizon Presbyopic NVA IOL provided satisfactory vision and low levels of photic phenomena in a high angle kappa patient who would potentially be excluded from presbyopia-correcting IOL implantation. Full article
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11 pages, 634 KB  
Article
Measuring and Correction Methods of H.-J. Haase Improve Binocular Vision in Patients with Severe Anisometropia
by Shun-Huan Wang, Ya-Yu Chen and Mei-Lan Ko
J. Clin. Med. 2025, 14(18), 6367; https://doi.org/10.3390/jcm14186367 - 9 Sep 2025
Viewed by 485
Abstract
Background/Objectives: To compare binocular vision status after spectacle correction using Measuring and Correction Methods of H.-J. Haase (MCH) and Optometric Extension Program (OEP) methods in patients with severe anisometropia and impaired fusion, including those with a history of monocular cataract surgery. Methods: This [...] Read more.
Background/Objectives: To compare binocular vision status after spectacle correction using Measuring and Correction Methods of H.-J. Haase (MCH) and Optometric Extension Program (OEP) methods in patients with severe anisometropia and impaired fusion, including those with a history of monocular cataract surgery. Methods: This retrospective, observational comparative study analyzed the medical records of 34 patients with severe anisometropia (≥3.00 D) who were fitted with spectacles at Yi-Ming Optometry Clinic between January 2019 and May 2023. Patients were aged 32 to 82 years and had no ocular or systemic comorbidities affecting visual function. Binocular vision data previously recorded using the MCH and OEP methods were extracted and analyzed. All data are expressed as mean ± standard error, and p-values ≤ 0.05 were considered statistically significant. Results: The mean anisometropia and heterophoria measurements were 5.51 ± 0.45 and 2.26 ± 0.32 D (∆), respectively. The mean MCH and OEP oculus uterque visual acuity measurements were −0.020 ± 0.010 and 0.040 ± 0.010 log-MAR (p < 0.001), respectively. In the right eye, the horizontal prisms for MCH and OEP were 0.780 ± 0.128 and 0.020 ± 0.020 (∆) (p < 0.001), whereas those of the left eye were 0.790 ± 0.119 and 0.040 ± 0.025 ∆ (p < 0.001), respectively. The mean MCH and OEP stereo vision measurements were 97.560 ± 7.888 and 167.120 ± 17.295 arcsec (p < 0.001), respectively. Conclusions: The findings indicate that MCH prism resulted in superior stereo vision and binocular visual acuity compared to OEP in severe anisometropia patients. Full article
(This article belongs to the Section Ophthalmology)
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12 pages, 570 KB  
Article
Advanced vs. Standard Monofocal IOLs: Optical Quality and Patient-Perceived Visual Outcomes
by Carla Charbel, Lidia Pérez-Sanz, Nuria Garzón, Francisco Poyales and Jesús Carballo
J. Clin. Med. 2025, 14(17), 6255; https://doi.org/10.3390/jcm14176255 - 4 Sep 2025
Viewed by 561
Abstract
Background/Objectives: The objective of this study is to compare the optical and visual quality provided by the advanced monofocal intraocular lens (IOL) ISOPure and the standard monofocal IOL MicroPure in cataract patients, using objective and subjective assessments. Methods: This prospective, single-blind clinical study [...] Read more.
Background/Objectives: The objective of this study is to compare the optical and visual quality provided by the advanced monofocal intraocular lens (IOL) ISOPure and the standard monofocal IOL MicroPure in cataract patients, using objective and subjective assessments. Methods: This prospective, single-blind clinical study includes 28 patients with cataracts, bilaterally implanted with either the ISOPure or MicroPure IOL. Eligible eyes had no ocular comorbidities and regular corneal astigmatism ≤ 1.00 D. Three months postoperatively, uncorrected distance and intermediate (UDVA, UIVA) and corrected distance and intermediate (CDVA, DCIVA) visual acuities were measured at 4 m, 80 cm, and 66 cm under photopic (85 cd/m2) and mesopic (3.5 cd/m2) conditions. Photic phenomena, including halo and glare, were evaluated. Objective optical quality was assessed using Objective Scattering Index (OSI), Modulation Transfer Function (MTF), Strehl Ratio (SR), and ocular aberrations. Subjective patient satisfaction was evaluated using Quality of Vision (QoV) and Catquest-9SF questionnaires. Results: Under photopic conditions, logMAR DCIVA at 80 cm, UIVA at 66 cm, and DCIVA at 66 cm were 0.18 ± 0.06, 0.25 ± 0.12, and 0.20 ± 0.13, respectively, for ISOPure, and 0.22 ± 0.06, 0.30 ± 0.09, and 0.25 ± 0.09 for MicroPure (p = 0.05, 0.02, and 0.05, respectively). No significant differences were observed in halo/glare size or intensity, OSI, MTF, or SR. However, statistically significant differences were found in higher-order total aberrations for pupil sizes of 3.0, 4.0 mm, and 5.0 mm. Questionnaires indicated greater satisfaction and functional intermediate vision with ISOPure. Conclusions: The ISOPure IOL offers superior intermediate vision without compromising distance vision, delivering a balanced combination of optical quality, functional performance, and patient satisfaction. Full article
(This article belongs to the Section Ophthalmology)
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15 pages, 2139 KB  
Article
Molecular Epidemiology of Carbapenem-Resistant P. aeruginosa and Enterobacterales Isolates from Clinical Infections and Their Susceptibility to Ceftazidime–Avibactam
by Jose-Rita Gerges, Sara Barada, Hadi Hussein, Ahmad Sleiman, Ziad Jabbour, Fatima El Rida, Abdallah Kurdi, Ghassan Matar, George Araj, Antoine Abou Fayad and Zeina Adnan Kanafani
Microorganisms 2025, 13(9), 2015; https://doi.org/10.3390/microorganisms13092015 - 29 Aug 2025
Viewed by 751
Abstract
The overuse of carbapenems has driven the rise of carbapenem-resistant Pseudomonas aeruginosa (CRPA) and Enterobacterales (CRE), against which ceftazidime–avibactam (CAZ-AVI) offers an alternative treatment. This study phenotypically determined resistance profiles of P. aeruginosa (PA), Escherichia coli (EC), and Klebsiella pneumoniae (KP) clinical isolates [...] Read more.
The overuse of carbapenems has driven the rise of carbapenem-resistant Pseudomonas aeruginosa (CRPA) and Enterobacterales (CRE), against which ceftazidime–avibactam (CAZ-AVI) offers an alternative treatment. This study phenotypically determined resistance profiles of P. aeruginosa (PA), Escherichia coli (EC), and Klebsiella pneumoniae (KP) clinical isolates to CAZ-AVI and investigated molecular resistance mechanisms genotypically. A total of 394 PA, 90 EC, and 84 KP isolates were collected from the American University of Beirut Medical Center. Antimicrobial susceptibility testing (AST) and whole-genome sequencing (WGS) were performed on 30 isolates per species. Results showed that 100% of KP, 63% of EC, and 100% of PA isolates were carbapenem-resistant. Among these, 73% of KP, 79% of EC, and 60% of PA were CAZ-AVI-resistant. WGS revealed diverse sequence types, plasmids, and antimicrobial resistance genes. Additionally, 100% of KP, 93% of EC, and 89% of PA isolates produced metallo-β-lactamases (MBLs). Mutations in ampD, ampR, and mexR were identified in CAZ-AVI-resistant, non-MBL-producing PA, whereas mutations in ompC, marR, and ampC were detected in CAZ-AVI-resistant, non-MBL-producing EC. While CAZ-AVI remains effective against most CRE and CRPA lacking MBLs, resistance to CAZ-AVI is multifactorial, commonly involving overexpression of efflux pumps and AmpC β-lactamases, loss of porin channels, and the presence of oxacillinases. Full article
(This article belongs to the Section Antimicrobial Agents and Resistance)
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10 pages, 820 KB  
Article
One-Month Real-World Comparison of Aflibercept 8 mg Versus 2 mg in Treatment-Naïve and Previously Treated Eyes with Neovascular Age-Related Macular Degeneration
by Takahiro Mizukami, Satoru Ueno, Soichiro Mishima and Yoshikazu Shimomura
Biologics 2025, 5(3), 25; https://doi.org/10.3390/biologics5030025 - 28 Aug 2025
Viewed by 684
Abstract
Background/Objectives: The relative efficacy of 8 mg aflibercept compared to 2 mg in treating neovascular age-related macular degeneration (nAMD) has not been fully established. This study aims to compare the visual and anatomical outcomes of aflibercept 8 mg versus 2 mg in patients [...] Read more.
Background/Objectives: The relative efficacy of 8 mg aflibercept compared to 2 mg in treating neovascular age-related macular degeneration (nAMD) has not been fully established. This study aims to compare the visual and anatomical outcomes of aflibercept 8 mg versus 2 mg in patients with nAMD in both treatment-naïve individuals with no history of anti-VEGF treatment and those previously treated with intravitreal injections. Methods: This retrospective study included 13 eyes treated with aflibercept 8 mg and 14 eyes with aflibercept 2 mg in treatment-naïve patients, along with 15 eyes switched to aflibercept 8 mg previously treated with other intravitreal injections and 15 eyes continued on aflibercept 2 mg in patients. Baseline and one-month post-injection changes in best-corrected visual acuity (BCVA) and central macular thickness (CMT) were assessed. Results: In treatment-naïve patients, the aflibercept 8 mg group showed a significant improvement in BCVA (logMAR 0.19 ± 0.23 to 0.13 ± 0.20, p = 0.0156), while the 2 mg group did not. Both doses reduced CMT significantly, with a greater reduction in the 8 mg group (dCMT 28.60% vs. 24.08%, p = 0.0220). In previously treated patients, no significant changes in BCVA were noted in either group; however, both groups showed significant reductions in CMT. Conclusions: Real-world data demonstrated that aflibercept 8 mg led to substantial improvements in anatomical outcomes one month after injection, irrespective of previous intravitreal injection history. However, significant improvements in visual outcomes were observed exclusively in treatment-naïve patients. Further large-scale, long-term studies are required to determine the proportion of patients who experience improvement and to assess whether these improvements are maintained over time. Full article
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25 pages, 4801 KB  
Article
Genotype–Phenotype Correlations in PRPH2 Retinopathies: A Comprehensive Analysis of 36 Patients from the Oxford Eye Hospital, UK
by Saoud Al-Khuzaei, Mital Shah, Arun Reginald, Edna Baba, Morag Shanks, Penny Clouston, Robert E. MacLaren, Stephanie Halford, Samantha R. De Silva and Susan M. Downes
Genes 2025, 16(9), 1016; https://doi.org/10.3390/genes16091016 - 27 Aug 2025
Viewed by 672
Abstract
Purpose: To investigate genotype–phenotype correlations in PRPH2-retinopathies in a cohort of 36 patients from the Oxford Eye Hospital and report on novel pathogenic variants. Methods: Clinical data, including best corrected visual acuities (BCVA), fundus autofluorescence (FAF), and optical coherence tomography (OCT) imaging, [...] Read more.
Purpose: To investigate genotype–phenotype correlations in PRPH2-retinopathies in a cohort of 36 patients from the Oxford Eye Hospital and report on novel pathogenic variants. Methods: Clinical data, including best corrected visual acuities (BCVA), fundus autofluorescence (FAF), and optical coherence tomography (OCT) imaging, were analysed. Genetic testing was performed using next-generation sequencing (NGS). Results: In this cohort, 26 different PRPH2 variants, including 8 novel variants, were identified. Variants were clustered in the D2 loop of the protein. A diverse range of phenotypes were observed: pseudo-Stargardt pattern dystrophy (PSPD) (47.2%), adult-onset vitelliform macular dystrophy (AVMD) (22.2%), pattern dystrophy (PD) (25.0%), atypical macular dystrophy (2.8%), and retinitis pigmentosa (RP) (2.8%). The mean age of symptom onset was 44.0 ± 14.4 years. Mean BCVA was 0.20 ± 0.54 logMAR OD and 0.14 ± 0.29 logMAR OS at baseline and 0.33 ± 0.40 logMAR OD and 0.32 ± 0.40 logMAR OS after a mean follow up duration of 6.0 ± 3.2 years (range 1–11 years). A thickened ellipsoid zone (EZ) was noted in 34/36 patients with a mean EZ thickness of 44.3 ± 11.3 µm OD and 42.7 ± 11.6 µm OS. No clear genotype–phenotype correlations were observed. Conclusions: The significant phenotypic range described in this study is consistent with the previously reported phenotypic variability in PRPH2 retinopathy and emphasises the complexity of establishing genotype–phenotype correlations in this disease. The thickness of the EZ on OCT may serve as a useful biomarker in distinguishing PRPH2 retinopathy from other phenocopies. These findings contribute to improved understanding of PRPH2 retinopathy and help inform diagnosis and genetic counselling. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
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54 pages, 22778 KB  
Article
On the Structural Design and Additive Construction Process of Martian Habitat Units Using In-Situ Resources on Mars
by Ehsan Dehghani Janabadi, Kasra Amini and Sana Rastegar
Aerospace 2025, 12(9), 761; https://doi.org/10.3390/aerospace12090761 - 25 Aug 2025
Viewed by 790
Abstract
Taking the leap to the secondary and tertiary generations of the missions to Mars, a comprehensive outline was presented for a cluster of Martian Habitat Units (MHUs) designed for long-term settlements of research crew in Melas Chasma, Valles Marineris, Mars. Unlike initial exploration [...] Read more.
Taking the leap to the secondary and tertiary generations of the missions to Mars, a comprehensive outline was presented for a cluster of Martian Habitat Units (MHUs) designed for long-term settlements of research crew in Melas Chasma, Valles Marineris, Mars. Unlike initial exploration missions, where primary survival is ensured through basic engineering solutions, this concept targets later-stage missions focused on long-term human presence. Accordingly, the MHUs are designed not only for functionality but also to support the social and cultural well-being of scientific personnel, resulting in larger and more complex structures than those typically proposed for early-stage landings. To address the construction and structural integrity of the MHUs, the current work presents a comprehensive analysis of the feasibility of semi-3D-printed structural systems using in situ material to minimize the cost and engineering effort of logistics and construction of the units. Regolith-based additive manufacturing was utilized as the primary material, and the response of the structure, not only to the gravitational loads but also to those applied from the exterior flow field and wind pressure distributions, was simulated, as well as the considerations regarding the contribution of the extreme interior/exterior pressure differences. The full analyses and structural results are presented and discussed in this manuscript, as well as insights on manufacturing and its feasibility on Mars. The analyses demonstrate the feasibility of constructing the complex architectural requirements of the MHUs and their cost-effectiveness through the use of in situ resources. The manuscript presents an iterative structural optimization process, with results detailed at each step. Structural elements were modeled using FEM-based analysis in Karamba-3D to minimize near-yielding effects such as buckling and excessive displacements. The final structural system was integrated with the architectural design to preserve the intended spatial and functional qualities. Full article
(This article belongs to the Special Issue Space System Design)
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17 pages, 1917 KB  
Article
Visual Outcomes of a Non-Diffractive Extended Depth-of-Focus Intraocular Lens in Patients with Early-Stage Age-Related Macular Degeneration
by Emilio Dorronzoro-Ramirez, Miguel Angel Sanchez-Tena, Cristina Alvarez-Peregrina, Jose Miguel Cardenas Rebollo, Dayan Flores Cervantes and Celia Sánchez-Ramos
J. Clin. Med. 2025, 14(17), 5953; https://doi.org/10.3390/jcm14175953 - 23 Aug 2025
Viewed by 690
Abstract
Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of visual impairment in older adults and often coexists with cataracts. The indication of presbyopia-correcting intraocular lenses (IOLs) in these patients remains controversial. This study aimed to evaluate the clinical performance of a [...] Read more.
Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of visual impairment in older adults and often coexists with cataracts. The indication of presbyopia-correcting intraocular lenses (IOLs) in these patients remains controversial. This study aimed to evaluate the clinical performance of a non-diffractive extended depth-of-focus (EDOF) IOL (LuxSmart™) compared to a monofocal plus IOL (Tecnis Eyhance™) in cataract patients with early-stage dry AMD. Methods: In this prospective observational study, 41 patients with early-stage AMD underwent bilateral cataract surgery with either LuxSmart™ or Tecnis Eyhance™ IOL implantation, targeting postoperative emmetropia. The eye selected for analysis was the first eye scheduled for surgery. Preoperative and postoperative evaluations included high and low-contrast distance visual acuity, intermediate and near visual acuity, defocus curves, ocular light scatter (halometry), and quality of life assessment (NEI VFQ-25). Postoperative biometric accuracy and refractive outcomes were also analyzed. Results: Both IOLs showed high refractive accuracy, with 100% of eyes within ±0.50 D of target. Postoperative uncorrected distance visual acuity was 0.10 ± 0.06 LogMAR for Eyhance and 0.07 ± 0.02 for LuxSmart (p = 0.06). Low contrast VA at 20% was 0.22 ± 0.11 (Eyhance) and 0.26 ± 0.16 (LuxSmart) (p = 0.49). Depth of focus was approximately 1.75 D for both lenses. Light scatter (LDI) improved postoperatively in both groups with no significant differences (p = 0.54). VFQ-25 scores showed improvement in daily activities, though no changes were observed in driving or mental health domains. Conclusions: Both lenses are safe and effective options for early AMD patients undergoing cataract surgery, providing good functional vision at multiple distances Full article
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12 pages, 1600 KB  
Article
Visual Outcomes and Patient Satisfaction with Extended Monovision—An Innovative Strategy to Achieve Spectacle Independence in Refractive Lens Exchange
by Dana Nagyova, Christoph Tappeiner, Andrej Blaha, David Goldblum and Dimitrios Kyroudis
J. Clin. Med. 2025, 14(16), 5684; https://doi.org/10.3390/jcm14165684 - 11 Aug 2025
Viewed by 671
Abstract
Background: Spectacle independence is a key goal in refractive lens exchange (RLE), especially in younger, high-expectation patients. This study evaluates a novel extended monovision approach combining a monofocal aspheric intraocular lens (IOL) in the dominant eye with a rotationally asymmetric bifocal extended-depth-of-focus [...] Read more.
Background: Spectacle independence is a key goal in refractive lens exchange (RLE), especially in younger, high-expectation patients. This study evaluates a novel extended monovision approach combining a monofocal aspheric intraocular lens (IOL) in the dominant eye with a rotationally asymmetric bifocal extended-depth-of-focus (EDOF) IOL in the non-dominant eye. The strategy aims to optimize full-range visual performance while minimizing photic phenomena. Methods: In this retrospective cohort study, presbyopic patients underwent bilateral RLE with a monofocal IOL (Hoya Vivinex XC1-SP; target: 0 diopters [D]) in the dominant eye and a rotationally asymmetric bifocal EDOF IOL (LENTIS LS-313 MF15; addition: +1.5 D; target: −1.25 D) in the non-dominant eye. Uncorrected distance visual acuity (UDVA, at 6 m), uncorrected intermediate visual acuity (UIVA, at 66 cm), and uncorrected near visual acuity (UNVA, at 36 cm) were assessed. Additional evaluations included binocular defocus curves, contrast sensitivity, stereoacuity, and photic phenomena. Spectacle independence and satisfaction were measured using the PRSIQ and NEI-RQL-42 questionnaires. Results: A total of 38 patients (76 eyes) were included. The mean postoperative binocular UDVA, UIVA, and UNVA were −0.03 ± 0.08, −0.08 ± 0.09, and 0.04 ± 0.08 logMAR, respectively. The defocus curve peaked at 0.0 D (6 m) with a mean visual acuity of −0.03 ± 0.08 logMAR. Functional vision better than 0.2 logMAR extended over defocus steps from +1.00 to −3.25 D. All patients were spectacle-independent for distance and intermediate vision, and 84% reported complete spectacle independence. Contrast sensitivity was within normal limits for age. Minimal photic phenomena were reported, and stereoacuity was preserved in 97% of patients (≤100 arcseconds). Conclusions: This innovative extended monovision approach, combining two different IOLs in a mini-monovision setup, provides excellent uncorrected visual acuity at all distances, high spectacle independence, and minimal side effects. It represents a compelling alternative to multifocal IOL implantation in presbyopic RLE candidates. Full article
(This article belongs to the Special Issue New Insights in Ophthalmic Surgery)
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8 pages, 449 KB  
Article
Feasibility and Postoperative Outcome After Duet Procedure for Reversible Multifocality in Eyes with Co-Pathologies
by Barbara S. Brunner, Martin Dirisamer, Nikolaus Luft, Stefan Kassumeh and Siegfried G. Priglinger
J. Clin. Med. 2025, 14(15), 5583; https://doi.org/10.3390/jcm14155583 - 7 Aug 2025
Viewed by 525
Abstract
Objectives: To evaluate the safety and efficacy of the simultaneous implantation of a monofocal capsular bag-fixated and a trifocal supplementary sulcus-fixated intraocular lens (duet procedure) in eyes with co-existing pathologies undergoing cataract or refractive lens surgery. Methods: In total, 80 eyes [...] Read more.
Objectives: To evaluate the safety and efficacy of the simultaneous implantation of a monofocal capsular bag-fixated and a trifocal supplementary sulcus-fixated intraocular lens (duet procedure) in eyes with co-existing pathologies undergoing cataract or refractive lens surgery. Methods: In total, 80 eyes of 40 consecutive patients, who underwent refractive lens exchange or cataract surgery and received the duet procedure due to minor co-pathologies, were included in this retrospective case series. Preoperative assessment comprised slit-lamp biomicroscopy, optical biometry, posterior-segment optical coherence tomography, corneal endothelial specular microscopy, corneal tomography, manifest refraction and distance and near visual acuity testing. Three months postoperatively, uncorrected distance (UDVA) and uncorrected near visual acuity (UNVA) were recorded. Results: The preoperative manifest refractive spherical equivalent (MRSE) was −0.31 ± 4.29 diopters (D), with a mean refractive astigmatism of −0.80 ± 0.60 D. At three months postoperatively, monocular UDVA and binocular UNVA significantly improved from 0.52 ± 0.42 logMAR and 0.32 ± 0.27 logMAR to 0.05 ± 0.09 logMAR and −0.03 ± 0.10 logMAR, respectively (both p < 0.0001). Conclusions: Reversible multifocality provided by the duet procedure appears to be a feasible option in eyes with mild co-existing pathologies, as it yields satisfactory visual and refractive outcomes with high safety. Full article
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25 pages, 11221 KB  
Article
A Mass Abatement Scalable System Through Managed Aquifer Recharge: Increased Efficiency in Extracting Mass from Polluted Aquifers
by Mario Alberto Garcia Torres, Alexandra Suhogusoff and Luiz Carlos Ferrari
Water 2025, 17(15), 2237; https://doi.org/10.3390/w17152237 - 27 Jul 2025
Viewed by 449
Abstract
A mass abatement scalable system through managed aquifer recharge (MAR-MASS) improves mass extraction from groundwater with a variable-density flow. This method is superior to conventional injection systems because it promotes uniform mass displacement, reduces density gradients, and increases mass extraction efficiency over time. [...] Read more.
A mass abatement scalable system through managed aquifer recharge (MAR-MASS) improves mass extraction from groundwater with a variable-density flow. This method is superior to conventional injection systems because it promotes uniform mass displacement, reduces density gradients, and increases mass extraction efficiency over time. Simulations of various scenarios involving hydrogeologic variables, including hydraulic conductivity, vertical anisotropy, specific yield, mechanical dispersion, molecular diffusion, and mass concentration in aquifers, have identified critical variables and parameters influencing mass transport interactions to optimize the system. MAR-MASS is adaptable across hydrogeologic conditions in aquifers that are 25–75 m thick, comprising unconsolidated materials with hydraulic conductivities between 5 and 100 m/d. It is effective in scenarios near coastal areas or in aquifers with variable-density flows within the continent, with mass concentrations of salts or solutes ranging from 3.5 to 35 kg/m3. This system employs a modular approach that offers scalable and adaptable solutions for mass extraction at specific locations. The integration of programming tools, such as Python 3.13.2, along with technological strategies utilizing parallelization techniques and high-performance computing, has facilitated the development and validation of MAR-MASS in mass extraction with remarkable efficiency. This study confirmed the utility of these tools for performing calculations, analyzing information, and managing databases in hydrogeologic models. Combining these technologies is critical for achieving precise and efficient results that would not be achievable without them, emphasizing the importance of an advanced technological approach in high-level hydrogeologic research. By enhancing groundwater quality within a comparatively short time frame, expanding freshwater availability, and supporting sustainable aquifer recharge practices, MAR-MASS is essential for improving water resource management. Full article
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27 pages, 31172 KB  
Article
Digital Twin for Analog Mars Missions: Investigating Local Positioning Alternatives for GNSS-Denied Environments
by Benjamin Reimeir, Amelie Leininger, Raimund Edlinger, Andreas Nüchter and Gernot Grömer
Sensors 2025, 25(15), 4615; https://doi.org/10.3390/s25154615 - 25 Jul 2025
Viewed by 686
Abstract
Future planetary exploration missions will rely heavily on efficient human–robot interaction to ensure astronaut safety and maximize scientific return. In this context, digital twins offer a promising tool for planning, simulating, and optimizing extravehicular activities. This study presents the development and evaluation of [...] Read more.
Future planetary exploration missions will rely heavily on efficient human–robot interaction to ensure astronaut safety and maximize scientific return. In this context, digital twins offer a promising tool for planning, simulating, and optimizing extravehicular activities. This study presents the development and evaluation of a digital twin for the AMADEE-24 analog Mars mission, organized by the Austrian Space Forum and conducted in Armenia in March 2024. Alternative local positioning methods were evaluated to enhance the system’s utility in Global Navigation Satellite System (GNSS)-denied environments. The digital twin integrates telemetry from the Aouda space suit simulators, inertial measurement unit motion capture (IMU-MoCap), and sensor data from the Intuitive Rover Operation and Collecting Samples (iROCS) rover. All nine experiment runs were reconstructed successfully by the developed digital twin. A comparative analysis of localization methods found that Simultaneous Localization and Mapping (SLAM)-based rover positioning and IMU-MoCap localization of the astronaut matched Global Positioning System (GPS) performance. Adaptive Cluster Detection showed significantly higher deviations compared to the previous GNSS alternatives. However, the IMU-MoCap method was limited by discontinuous segment-wise measurements, which required intermittent GPS recalibration. Despite these limitations, the results highlight the potential of alternative localization techniques for digital twin integration. Full article
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17 pages, 7199 KB  
Article
YED-Net: Yoga Exercise Dynamics Monitoring with YOLOv11-ECA-Enhanced Detection and DeepSORT Tracking
by Youyu Zhou, Shu Dong, Hao Sheng and Wei Ke
Appl. Sci. 2025, 15(13), 7354; https://doi.org/10.3390/app15137354 - 30 Jun 2025
Viewed by 759
Abstract
Against the backdrop of the deep integration of national fitness and sports science, this study addresses the lack of standardized movement assessment in yoga training by proposing an intelligent analysis system that integrates an improved YOLOv11-ECA detector with the DeepSORT tracking algorithm. A [...] Read more.
Against the backdrop of the deep integration of national fitness and sports science, this study addresses the lack of standardized movement assessment in yoga training by proposing an intelligent analysis system that integrates an improved YOLOv11-ECA detector with the DeepSORT tracking algorithm. A dynamic adaptive anchor mechanism and an Efficient Channel Attention (ECA) module are introduced, while the depthwise separable convolution in the C3k2 module is optimized with a kernel size of 2. Furthermore, a Parallel Spatial Attention (PSA) mechanism is incorporated to enhance multi-target feature discrimination. These enhancements enable the model to achieve a high detection accuracy of 98.6% mAP@0.5 while maintaining low computational complexity (2.35 M parameters, 3.11 GFLOPs). Evaluated on the SND Sun Salutation Yoga Dataset released in 2024, the improved model achieves a real-time processing speed of 85.79 frames per second (FPS) on an RTX 3060 platform, with an 18% reduction in computational cost compared to the baseline. Notably, it achieves a 0.9% improvement in AP@0.5 for small targets (<20 px). By integrating the Mars-smallCNN feature extraction network with a Kalman filtering-based trajectory prediction module, the system attains 58.3% Multiple Object Tracking Accuracy (MOTA) and 62.1% Identity F1 Score (IDF1) in dense multi-object scenarios, representing an improvement of approximately 9.8 percentage points over the conventional YOLO+DeepSORT method. Ablation studies confirm that the ECA module, implemented via lightweight 1D convolution, enhances channel attention modeling efficiency by 23% compared to the original SE module and reduces the false detection rate by 1.2 times under complex backgrounds. This study presents a complete “detection–tracking–assessment” pipeline for intelligent sports training. Future work aims to integrate 3D pose estimation to develop a closed-loop biomechanical analysis system, thereby advancing sports science toward intelligent decision-making paradigms. Full article
(This article belongs to the Special Issue Advances in Image Recognition and Processing Technologies)
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