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  • Review
  • Open Access
57 Citations
11,418 Views
17 Pages

From Genome to Phenotype: An Integrative Approach to Evaluate the Biodiversity of Lactococcus lactis

  • Valérie Laroute,
  • Hélène Tormo,
  • Christel Couderc,
  • Muriel Mercier-Bonin,
  • Pascal Le Bourgeois,
  • Muriel Cocaign-Bousquet and
  • Marie-Line Daveran-Mingot

Lactococcus lactis is one of the most extensively used lactic acid bacteria for the manufacture of dairy products. Exploring the biodiversity of L. lactis is extremely promising both to acquire new knowledge and for food and health-driven application...

  • Article
  • Open Access
25 Citations
4,916 Views
14 Pages

Immunomodulatory Activity of Lactococcus lactis GCWB1176 in Cyclophosphamide-Induced Immunosuppression Model

  • Sun Woo Jin,
  • Gi Ho Lee,
  • Min Jung Jang,
  • Gyeong Eun Hong,
  • Jae Young Kim,
  • Gi Deok Park,
  • Hui Jin,
  • Hyun Su Kim,
  • Jae Ho Choi and
  • Yong Pil Hwang
  • + 3 authors

Recently, Lactococcus lactis subsp. lactis has been reported to have immunostimulating properties in an immunosuppressed-animal model. However, the immunological activities of Lactococcus lactis and the molecular mechanisms remain unclear. In this re...

  • Article
  • Open Access
19 Citations
6,098 Views
19 Pages

Immunostimulatory Activity of Lactococcus lactis subsp. lactis CAB701 Isolated from Jeju Cabbage

  • Huijin Jeong,
  • Suin Kim,
  • Un-Sik Hwang,
  • Hyukjoon Choi and
  • Young-Seo Park

This study explored the potential of Lactococcus lactis subsp. lactis CAB701 as a probiotic strain, focusing on its immunostimulatory properties. Despite adverse conditions in the gastrointestinal environment, this strain exhibited remarkable surviva...

  • Article
  • Open Access
12 Citations
3,670 Views
12 Pages

Antimicrobial Activity of Peptides Produced by Lactococcus lactis subsp. lactis on Swine Pathogens

  • Fernando M. M. Sanca,
  • Iago R. Blanco,
  • Meriellen Dias,
  • Andrea M. Moreno,
  • Simone M. M. K. Martins,
  • Marco A. Stephano,
  • Maria A. Mendes,
  • Carlos M. N. Mendonça,
  • Wellison A. Pereira and
  • Ricardo P. S. Oliveira
  • + 2 authors

28 July 2023

Swine production is of great importance worldwide and has huge economic and commercial impact. Due to problems with bacterial infection, the use of antimicrobials has increased in the last decades, particularly in Latin America and Asia. This has led...

  • Article
  • Open Access
609 Views
25 Pages

Genetic Characterisation of Closely Related Lactococcus lactis Strains Used in Dairy Starter Cultures

  • Yuliya E. Uvarova,
  • Tamara M. Khlebodarova,
  • Asya R. Vasilieva,
  • Aleksandra A. Shipova,
  • Vladimir N. Babenko,
  • Andrey V. Zadorozhny,
  • Nikolay M. Slynko,
  • Natalia V. Bogacheva,
  • Ekaterina Y. Bukatich and
  • Sergey E. Peltek
  • + 4 authors

27 December 2025

The complex microbiota of cheese starters plays a key role in determining the structure and flavour of the final product, primarily through their acid-forming capacity, protease activity, and exopolysaccharide synthesis. However, the specific microbi...

  • Article
  • Open Access
45 Citations
5,598 Views
14 Pages

15 October 2018

Edible films have gradually become a research focus for food packaging materials due to a variety of benefits, including environmental friendliness, good barrier properties, and good carrying capacity. In this experimental study, we used sodium algin...

  • Article
  • Open Access
7 Citations
2,706 Views
10 Pages

Effects of the Autochthonous Probiotic Bacteria Lactobacillus plantarum B and Lactococcus lactis Subsp. lactis S1 on the Proteolysis of Croatian Cheese Ripened in a Lambskin Sack (Sir iz Mišine)

  • Marija Vrdoljak,
  • Milna Tudor Kalit,
  • Iva Dolenčić Špehar,
  • Biljana Radeljević,
  • Marko Jelić,
  • Sandra Mandinić,
  • Jadranka Frece and
  • Samir Kalit

This study aims to determine the effects of the autochthonous probiotic bacteria Lactobacillus plantarum B (currently Lactiplantibacillus plantarum) and Lactococcus lactis subsp. lactis S1 on proteolysis during the ripening of Sir iz mišine&md...

  • Article
  • Open Access
14 Citations
4,354 Views
19 Pages

Design of Lactococcus lactis Strains Producing Garvicin A and/or Garvicin Q, Either Alone or Together with Nisin A or Nisin Z and High Antimicrobial Activity against Lactococcus garvieae

  • Javier Feito,
  • Carlos Araújo,
  • Sara Arbulu,
  • Diogo Contente,
  • Beatriz Gómez-Sala,
  • Lara Díaz-Formoso,
  • Estefanía Muñoz-Atienza,
  • Juan Borrero,
  • Luis M. Cintas and
  • Pablo E. Hernández

2 March 2023

Lactococcus garvieae is a main ichthyopathogen in rainbow trout (Oncorhynchus mykiss, Walbaum) farming, although bacteriocinogenic L. garvieae with antimicrobial activity against virulent strains of this species have also been identified. Some of the...

  • Article
  • Open Access
27 Citations
7,612 Views
15 Pages

Metabolic Profiling of Lactococcus lactis Under Different Culture Conditions

  • Kamalrul Azlan Azizan,
  • Syarul Nataqain Baharum and
  • Normah Mohd Noor

3 July 2012

Gas chromatography mass spectrometry (GC-MS) and headspace gas chromatography mass spectrometry (HS/GC-MS) were used to study metabolites produced by Lactococcus lactis subsp. cremoris MG1363 grown at a temperature of 30 °C with and without agitation...

  • Article
  • Open Access
6 Citations
3,827 Views
15 Pages

Lectin-Mediated Binding of Engineered Lactococcus lactis to Cancer Cells

  • Tina Vida Plavec,
  • Abida Zahirović,
  • Petra Zadravec,
  • Jerica Sabotič and
  • Aleš Berlec

Lectins have been increasingly utilized as carriers for targeted drug delivery based on their specific binding to glycans located on mammalian cells. This study employed two lectins, B subunit of bacterial Shiga holotoxin (Stx1B) and fungal Clitocybe...

  • Review
  • Open Access
7 Citations
4,727 Views
16 Pages

Lactococcus lactis is a food-grade, and generally recognized as safe, bacterium, which making it ideal for producing plasmid DNA (pDNA) or recombinant proteins for industrial or pharmaceutical applications. The present paper reviews the major finding...

  • Review
  • Open Access
37 Citations
23,901 Views
40 Pages

Lactococcus lactis in Dairy Fermentation—Health-Promoting and Probiotic Properties

  • Kristina Kondrotiene,
  • Paulina Zavistanaviciute,
  • Jurgita Aksomaitiene,
  • Aleksandr Novoslavskij and
  • Mindaugas Malakauskas

The use of lactic acid bacteria (LAB) in the fermentation process to produce fermented foods has a long history. Furthermore, LAB are beneficial microorganisms known for their health-promoting characteristics. During fermentation, LAB have the capaci...

  • Article
  • Open Access
799 Views
7 Pages

The Effects of Lactococcus lactis subsp. lactis and Its Supernatant on Some Bacteriological and Sensory Values in Rainbow Trout (Onchorhynchus mykiss) Fillets

  • Asad Abbaspour Anbi,
  • Vadood Razavilar,
  • Moslem Neyriz Naghadehi,
  • Masoud Seidgar,
  • Ali Nekuiefard and
  • Yoseif Ali Asadpour Osalou

Lactic Acid Bacteria (LAB) have a great potential as bio-preservatives. The live cells and supernatant Lactococcus lactis subsp. lactis induced bacteriological changes in Onchorhynchus mykiss fillet by spray and immersion methods was studied during v...

  • Article
  • Open Access
23 Citations
9,256 Views
16 Pages

Functional Expression of an Orchid Fragrance Gene in Lactococcus lactis

  • Adelene Ai Lian Song,
  • Janna O. Abdullah,
  • Mohd Puad Abdullah,
  • Norazizah Shafee and
  • Raha A. Rahim

2 February 2012

Vanda Mimi Palmer (VMP), an orchid hybrid of Vanda tesselata and Vanda Tan Chay Yan is a highly scented tropical orchid which blooms all year round. Previous studies revealed that VMP produces a variety of isoprenoid volatiles during daylight. Isopre...

  • Article
  • Open Access
15 Citations
4,930 Views
9 Pages

Characterization and Antimicrobial Susceptibility of Lactococcus lactis Isolated from Endodontic Infections in Ouagadougou, Burkina Faso

  • Wendpoulomdé Aimé Désiré Kaboré,
  • René Dembélé,
  • Touwendsida Serge Bagré,
  • Ali Konaté,
  • Sylvie Boisramé,
  • Valérie Chevalier,
  • Tarcissus Konsem,
  • Alfred S. Traoré and
  • Nicolas Barro

10 December 2018

Background: This study aimed to characterize and test the antimicrobial susceptibility of Lactococcus lactis isolated in endodontic infections in Burkina Faso. Material and methods: This was a prospective study conducted at the Municipal Oral Health...

  • Review
  • Open Access
32 Citations
10,349 Views
22 Pages

22 January 2022

Membrane proteins play key roles in most crucial cellular processes, ranging from cell-to-cell communication to signaling processes. Despite recent improvements, the expression of functionally folded membrane proteins in sufficient amounts for functi...

  • Article
  • Open Access
21 Citations
3,754 Views
13 Pages

A native Lactococcus lactis subsp. lactis UTNGt28 (GenBank accession no: MG675576.1) isolated from Amazonian fruit of the tropical Caimitillo (Chrysophyllum oliviforme) tree and the commercial strain Lactococcus lactis subsp lactis ATCC11454 (LacAT)...

  • Article
  • Open Access
9 Citations
3,287 Views
15 Pages

Suitability of the Nisin Z-producer Lactococcus lactis subsp. lactis CBM 21 to be Used as an Adjunct Culture for Squacquerone Cheese Production

  • Lorenzo Siroli,
  • Francesca Patrignani,
  • Margherita D’Alessandro,
  • Elisa Salvetti,
  • Sandra Torriani and
  • Rosalba Lanciotti

30 April 2020

This research investigated the technological and safety effects of the nisin Z producer Lactococcus lactis subsp. lactis CBM 21, tested as an adjunct culture for the making of Squacquerone cheese in a pilot-scale plant. The biocontrol agent remained...

  • Article
  • Open Access
36 Citations
5,774 Views
18 Pages

19 April 2021

Clostridium tyrobutyricum spores survive milk pasteurization and cause late blowing of cheeses and significant economic loss. The effectiveness of nisin-producing Lactococcus lactis ssp. lactis 32 as a protective strain for control the C. tyrobutyric...

  • Article
  • Open Access
30 Citations
5,641 Views
15 Pages

Whole-Genome Sequence of Lactococcus lactis Subsp. lactis LL16 Confirms Safety, Probiotic Potential, and Reveals Functional Traits

  • Justina Mileriene,
  • Jurgita Aksomaitiene,
  • Kristina Kondrotiene,
  • Tora Asledottir,
  • Gerd Elisabeth Vegarud,
  • Loreta Serniene and
  • Mindaugas Malakauskas

Safety is the most important criteria of any substance or microorganism applied in the food industry. The whole-genome sequencing (WGS) of an indigenous dairy isolate LL16 confirmed it to be Lactococcus lactis subsp. lactis with genome size 2,589,406...

  • Review
  • Open Access
384 Views
29 Pages

Lactococcus lactis as a New Strategy for Oral Vaccination: Current Insights and Future Perspectives

  • Jonnathan Grossolli-Galvez,
  • Mónica Imarai,
  • Jorge A. Soto and
  • Abel E. Vasquez

Lactococcus lactis, a safe food-grade lactic acid bacterium, has attracted increasing attention as a live biotherapeutic platform for mucosal vaccine development. Its genetic simplicity, absence of endotoxins, and availability of well-characterized i...

  • Article
  • Open Access
3 Citations
2,841 Views
10 Pages

Suppressive Effect of Lactococcus lactis subsp. cremoris YRC3780 on a Murine Model of Japanese Cedar Pollinosis

  • Kenji Uchida,
  • Kenichi Iida,
  • Ikumi Fujioka,
  • Satoshi Hachimura and
  • Osamu Kaminuma

14 November 2022

Accumulating evidence suggests that Lactococcus lactis subsp. cremoris YRC3780 isolated from kefir has the potential to alleviate allergic responses. Herein, we investigated the effect of YRC3780 on a murine model of Japanese cedar pollinosis (JCP)....

  • Article
  • Open Access
19 Citations
5,335 Views
18 Pages

Targeting Melanoma Hypoxia with the Food-Grade Lactic Acid Bacterium Lactococcus Lactis

  • Rodolfo Garza-Morales,
  • Beatriz E. Rendon,
  • Mohammad Tariq Malik,
  • Jeannete E. Garza-Cabrales,
  • Anne Aucouturier,
  • Luis G. Bermúdez-Humarán,
  • Kelly M. McMasters,
  • Lacey R. McNally and
  • Jorge G. Gomez-Gutierrez

13 February 2020

Melanoma is the most aggressive form of skin cancer. Hypoxia is a feature of the tumor microenvironment that reduces efficacy of immuno- and chemotherapies, resulting in poor clinical outcomes. Lactococcus lactis is a facultative anaerobic gram-posit...

  • Article
  • Open Access
3 Citations
2,277 Views
13 Pages

Control of Bacterial Phenotype and Chromosomal Gene Expression by Single Plasmids of Lactococcus lactis IL594

  • Katarzyna Kosiorek,
  • Anna Koryszewska-Bagińska,
  • Marek Skoneczny and
  • Tamara Aleksandrzak-Piekarczyk

Plasmid-free Lactococcus lactis IL1403 is one of the best-characterized representatives of lactic acid bacteria (LAB), intensively used in broad microbiology worldwide. Its parent strain, L. lactis IL594, contains seven plasmids (pIL1–pIL7) wit...

  • Article
  • Open Access
49 Citations
6,484 Views
14 Pages

In Vitro Antioxidant and Antihypertensive Activity of Edible Insects Flours (Mealworm and Grasshopper) Fermented with Lactococcus lactis Strains

  • Adilene Mendoza-Salazar,
  • Lourdes Santiago-López,
  • María J. Torres-Llanez,
  • Adrián Hernández-Mendoza,
  • Belinda Vallejo-Cordoba,
  • Andrea M. Liceaga and
  • Aarón F. González-Córdova

The objective of the present study was to evaluate the potential antioxidant and angiotensin converting enzyme inhibition (ACEI) activity of edible insect flours fermented with Lactococcus lactis strains. For the fermentation, mealworm and grasshoppe...

  • Article
  • Open Access
3 Citations
2,124 Views
16 Pages

Assessment of Encapsulated Probiotic Lactococcus lactis A12 Viability Using an In Vitro Digestion Model for Tilapia

  • Marcelo Fernando Valle Vargas,
  • María Ximena Quintanilla-Carvajal,
  • Luisa Villamil-Diaz,
  • Ruth Yolanda Ruiz Pardo and
  • Francisco Javier Moyano

5 July 2024

Probiotics face harsh conditions during their transit through the gastrointestinal tract (GIT) of fish because of low-pH environments and intestine fluid. Therefore, the evaluation of probiotic viability under simulated gastrointestinal conditions is...

  • Article
  • Open Access
13 Citations
3,785 Views
16 Pages

Nasally Administered Lactococcus lactis Secreting Heme Oxygenase-1 Attenuates Murine Emphysema

  • Kentaro Yumoto,
  • Takashi Sato,
  • Kentaro Nakashima,
  • Fu Namai,
  • Suguru Shigemori,
  • Takeshi Shimosato and
  • Takeshi Kaneko

27 October 2020

Emphysema, a type of lung-destroying condition associated with chronic obstructive pulmonary disease (COPD), is an inflammatory lung disease mainly due to cigarette smoke exposure. As there is no curative therapy, prevention should be considered firs...

  • Article
  • Open Access
9 Citations
4,832 Views
20 Pages

While looking for novel insect-associated phages, a unique siphophage, Nocturne116, was isolated from a deceased local moth specimen along with its host, which was identified by 16S rRNA gene sequencing as a strain of Lactococcus lactis. Next-generat...

  • Article
  • Open Access
53 Citations
3,949 Views
13 Pages

30 September 2006

The effect of different protectants and the impact of the initial cell density on the viability of Lactococcus lactis Sr. 3.54 subjected to freeze-thawing and freezedrying was studied. Several additives were tested as protective agents against freezi...

  • Article
  • Open Access
30 Citations
8,111 Views
14 Pages

Probiotic Properties of Lactococcus lactis Strains Isolated from Natural Whey Starter Cultures

  • Ida De Chiara,
  • Rosangela Marasco,
  • Milena Della Gala,
  • Alessandra Fusco,
  • Giovanna Donnarumma and
  • Lidia Muscariello

21 March 2024

Lactococcus lactis is a lactic acid bacterium (LAB), generally recognized as safe, and has been widely used in the food industry, especially in fermented dairy products. Numerous studies have evaluated the technological and probiotic properties of la...

  • Article
  • Open Access
16 Citations
5,698 Views
14 Pages

In the present study, we isolated and characterized Lactococcus lactis (L. lactis) subsp. lactis from a female Cuvier’s beaked whale (Ziphius cavirostris) stranded in Shizuoka, Japan. Only five isolates (CBW1-5), grown on Lactobacilli de Man Ro...

  • Article
  • Open Access
21 Citations
4,816 Views
19 Pages

Genomic Features and Construction of Streamlined Genome Chassis of Nisin Z Producer Lactococcus lactis N8

  • Wanjin Qiao,
  • Fulu Liu,
  • Xing Wan,
  • Yu Qiao,
  • Ran Li,
  • Zhenzhou Wu,
  • Per Erik Joakim Saris,
  • Haijin Xu and
  • Mingqiang Qiao

Lactococcus lactis is a commonly used fermenting bacteria in cheese, beverages and meat products. Due to the lack of simplified chassis strains, it has not been widely used in the fields of synthetic biology. Thus, the construction of lactic acid bac...

  • Article
  • Open Access
13 Citations
4,911 Views
15 Pages

31 October 2020

This study assessed the color improvement via zinc protoporphyrin IX (ZnPP) formation in nitrite-free, dry-cured sausages processed using five varieties of ZnPP-forming lactic acid bacteria (LAB). The ZnPP contents and color intensity of the sausages...

  • Article
  • Open Access
26 Citations
5,521 Views
13 Pages

Effect of the Lactococcus Lactis 11/19-B1 Strain on Atopic Dermatitis in a Clinical Test and Mouse Model

  • Takato Suzuki,
  • Kyoko Nishiyama,
  • Koji Kawata,
  • Kotaro Sugimoto,
  • Masato Isome,
  • Shigeo Suzuki,
  • Ruriko Nozawa,
  • Yoko Ichikawa,
  • Yoshihisa Watanabe and
  • Tatsuo Suzutani

14 March 2020

Some lactic acid bacteria (LAB) are known to improve atopic dermatitis (AD) through the regulation and stimulation of the host immune system. In this study, we found that ingestion of yogurt containing Lactococcus lactis 11/19-B1 strain (L. lactis 11...

  • Article
  • Open Access
11 Citations
9,159 Views
12 Pages

The study of growth of Lactococcus lactis NCIM 2114, a nisin producer, was modeled using continuously generated concentration data for growth in fermenter. The sigmoidal growth functions, Logistic, Gompertz, and Richards were used to fit the data....

  • Article
  • Open Access
29 Citations
4,431 Views
16 Pages

Unravelling the Potential of Lactococcus lactis Strains to Be Used in Cheesemaking Production as Biocontrol Agents

  • Danka Bukvicki,
  • Lorenzo Siroli,
  • Margherita D’Alessandro,
  • Sofia Cosentino,
  • Ismail Fliss,
  • Laila Ben Said,
  • Hebatoallah Hassan,
  • Rosalba Lanciotti and
  • Francesca Patrignani

7 December 2020

This research, developed within an exchange program between Italy and Canada, represents the first step of a three-year project intended to evaluate the potential of nisin-producing Lactococcus lactis strains isolated from Italian and Canadian dairy...

  • Article
  • Open Access
497 Views
17 Pages

4 December 2025

Sour cream is a functional dairy product with a unique taste and high nutritional value. In this study, Lactococcus lactis grx602, a strain capable of degrading milk fat, was used to produce sour cream (a fermented dairy-based emulsion, designated as...

  • Article
  • Open Access
1,467 Views
14 Pages

30 December 2024

Lactococcus lactis is a potential bacterial cell factory to develop delivery systems for vaccines and therapeutic proteins. Much progress has been made in applications using engineered L. lactis against, e.g., inflammatory bowel disease and cervical...

  • Article
  • Open Access
6 Citations
2,142 Views
21 Pages

Biocomposite Material Based on Lactococcus lactis sp. Immobilized in Natural Polymer Matrix for Pharmaceutical Removal from Aqueous Media

  • Narcis-Teodor Niță,
  • Elena-Mirela Suceveanu,
  • Florin Marian Nedeff,
  • Ovidiu Tița and
  • Lăcrămioara Rusu

26 June 2024

Ecosystems are negatively impacted by pharmaceutical-contaminated water in different ways. In this work, a new biosorbent obtained by immobilizing Lactococcus lactis in a calcium alginate matrix was developed for the removal of pharmaceuticals from a...

  • Article
  • Open Access
889 Views
18 Pages

29 September 2025

Inducible CRISPR interference (CRISPRi) systems were established in Lactococcus lactis using both plasmid and chromosomal approaches. Expression of nuclease-deficient Cas9 (dCas9) from Streptococcus pyogenes was placed under the control of the nisin-...

  • Article
  • Open Access
12 Citations
7,079 Views
22 Pages

Efficacy of Lactococcus lactis subsp. lactis LY-66 and Lactobacillus plantarum PL-02 in Enhancing Explosive Strength and Endurance: A Randomized, Double-Blinded Clinical Trial

  • Mon-Chien Lee,
  • Yi-Ju Hsu,
  • Mu-Tsung Chen,
  • Yi-Wei Kuo,
  • Jia-Hung Lin,
  • Yu-Chieh Hsu,
  • Yen-Yu Huang,
  • Ching-Min Li,
  • Shin-Yu Tsai and
  • Chi-Chang Huang
  • + 2 authors

18 June 2024

Probiotics are posited to enhance exercise performance by influencing muscle protein synthesis, augmenting glycogen storage, and reducing inflammation. This double-blind study randomized 88 participants to receive a six-week intervention with either...

  • Article
  • Open Access
34 Citations
5,450 Views
15 Pages

GABA-Producing Lactococcus lactis Strains Isolated from Camel’s Milk as Starters for the Production of GABA-Enriched Cheese

  • Begoña Redruello,
  • Yasmine Saidi,
  • Lorena Sampedro,
  • Victor Ladero,
  • Beatriz del Rio and
  • Miguel A. Alvarez

17 March 2021

The multiple health benefits attributed to the bioactive compound γ-aminobutyric acid (GABA) have prompted the food industry to investigate the development of functional GABA-rich foods via the use of GABA-producing microorganisms. This study reports...

  • Review
  • Open Access
12 Citations
11,764 Views
30 Pages

30 January 2021

The Lactococcus lactis bacterium found in different natural environments is traditionally associated with the fermented food industry. But recently, its applications have been spreading to the pharmaceutical industry, which has exploited its probioti...

  • Article
  • Open Access
3 Citations
2,389 Views
13 Pages

Secretion of Bacillus amyloliquefaciens Transglutaminase from Lactococcus lactis and Its Enhancement of Food Gel Properties

  • Tiange Ma,
  • Xingjiang Li,
  • Manuel Montalbán-López,
  • Xuefeng Wu,
  • Zhi Zheng and
  • Dongdong Mu

20 October 2022

(1) Background: Microbial transglutaminases (MTGase) catalyze protein crosslink. This is useful in the food industry to improve gelation, water holding capacity, and emulsifying capacity during foodstuff manufacturing. The production of MTGase in wil...

  • Article
  • Open Access
1,322 Views
20 Pages

Lactococcus lactis (L. lactis) is a pathogenic Gram-positive, catalase-negative coccobacillus (GPCN) associated with bovine mastitis. In this study, nine strains of L. lactis were successfully isolated and characterized from 457 milk samples from cow...

  • Article
  • Open Access
40 Citations
6,821 Views
14 Pages

Influence of Culture Conditions and Medium Compositions on the Production of Bacteriocin-Like Inhibitory Substances by Lactococcus lactis Gh1

  • Roslina Jawan,
  • Sahar Abbasiliasi,
  • Joo Shun Tan,
  • Shuhaimi Mustafa,
  • Murni Halim and
  • Arbakariya B. Ariff

Antibacterial peptides or bacteriocins produced by many strains of lactic acid bacteria have been used as food preservatives for many years without any known adverse effects. Bacteriocin titres can be modified by altering the physiological and nutrit...

  • Article
  • Open Access
2 Citations
1,652 Views
19 Pages

28 February 2025

Due to the barriers imposed by the restriction–modification (RM) system, Nisin-producing industrial strains of Lactococcus lactis often encounter low transformation efficiency, which seriously hinders the widespread application of genetic engin...

  • Article
  • Open Access
24 Citations
5,609 Views
21 Pages

23 August 2022

The gut microbiota is responsible for differential anticancer drug efficacies by modulating the host immune system and the tumor microenvironment. Interestingly, this differential effect is highly strain-specific. For example, certain strains can dir...

  • Article
  • Open Access
3 Citations
2,344 Views
16 Pages

The main purpose of the present study was to evaluate the anti-inflammatory activity of Lactococcus lactis BL52 and isolate active substances responsible for anti-inflammatory activity. Head-kidney (HK) macrophages were used for in vitro bioassay-gui...

  • Article
  • Open Access
15 Citations
3,853 Views
15 Pages

14 January 2021

As a multifunctional polypeptide, epidermal growth factor (EGF) increases growth performance or enhances resistance to diseases in commercial broilers under adverse conditions. In this study, a recombinant Lactococcus lactis was established to produc...

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