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The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials
- Jean Claude Didelot Tomani,
- Vedaste Kagisha,
- Alembert Tiabou Tchinda,
- Olivia Jansen,
- Allison Ledoux,
- Luc Vanhamme,
- Michel Frederich,
- Raymond Muganga and
- Jacob Souopgui
The activation of NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome and/or its components is associated with the physio-pathogenesis of many respiratory diseases including asthma, COPD (chronic obstructive pulmonary disease), SAR...