Search Results (2,712)

Avocado (Persea americana), originally from Mesoamerica, has emerged as a focus of intense scientific and industrial interest due to its unique combination of nutritional richness, bioactive potential, and technological versatility. Its pulp, widely consumed across the globe, is notably abundant in monounsaturated fatty acids, especially oleic acid, which can comprise over two-thirds of its lipid content. In addition, it provides significant levels of dietary fiber, fat-soluble vitamins such as A, D, E and K, carotenoids, tocopherols, and phytosterols like β-sitosterol. These constituents are consistently associated with antioxidant, anti-inflammatory, glycemic regulatory, and cardioprotective effects, supported by a growing body of experimental and clinical evidence. This review offers a comprehensive and critical synthesis of the chemical composition and functional properties of avocado, with particular emphasis on its lipid profile, phenolic compounds, and phytosterols. It also explores recent advances in environmentally sustainable extraction techniques, including ultrasound-assisted and microwave-assisted processes, as well as the application of natural deep eutectic solvents. These technologies have demonstrated improved efficiency in recovering bioactives while aligning with the principles of green chemistry. The use of avocado-derived ingredients in nanostructured delivery systems and their incorporation into functional foods, cosmetics, and health-promoting formulations is discussed in detail. Additionally, the potential of native cultivars and the application of precision nutrition strategies are identified as promising avenues for future innovation. Taken together, the findings underscore the avocado’s relevance as a high-value matrix for sustainable development. Future research should focus on optimizing extraction protocols, clarifying pharmacokinetic behavior, and ensuring long-term safety in diverse applications. Full article

This study investigated white wastewater (WW) as a potential source of antimicrobial peptides, employing hydrolysis with Pronase E followed by separation through electrodialysis with ultrafiltration membranes (EDUF) to increase the value of dairy components within a circular economy framework. The WW hydrolysate was divided into two key fractions: the cationic recovery compartment (CRC) and the anionic recovery compartment (ARC). The EDUF process effectively separated peptides, with peptide migration rates reaching 6.83 ± 0.59 g/m²·h for CRC and 6.19 ± 0.66 g/m²·h for ARC. Furthermore, relative energy consumption (REC) increased from 1.15 Wh/g to 2.05 Wh/g over three hours, in line with trends observed in recent studies on electrodialysis energy use. Although 29 peptides were statistically selected from the CRC (20) and ARC (9) compartments, no antibacterial activity was exhibited against Clostridium tyrobutyricum and Pseudomonas aeruginosa; however, antifungal activity was observed in the feed and ARC compartments. Peptides from the ARC demonstrated activity against Mucor racemosus (MIC = 0.156 mg/mL) and showed selective antifungal effects against Penicillium commune (MIC = 0.156 mg/mL). This innovative approach paves the way for improving the recovery of anionic peptides through further optimization of the EDUF process. Future perspectives include synthesizing selected peptides and evaluating their antifungal efficacy against these and other microbial strains, offering exciting potential for applications in food preservation and beyond. Full article

As the body of knowledge on feline mammary tumors (FMTs) continues to grow, their histological classification and grading systems have undergone revisions and updates to better reflect the biological behavior of these tumors. In this review, the historical evolution of these frameworks is traced and later revisited in the context of their prognostic relevance. Numerous studies have investigated clinicopathological prognostic factors in feline mammary carcinomas (FMCs); however, the heterogeneity in assessment methods, inclusion criteria for survival analysis, and the clinical endpoints considered can often complicate direct comparisons across different studies and may contribute to seemingly conflicting results. Furthermore, the small cohort size of many studies limits the robustness and transferability of their findings. This paper provides an updated overview of the epidemiological, clinical, and pathological prognostic factors of these tumors, while also highlighting current challenges, methodological limitations, and areas for future improvement. Full article

The preparation and use of iron oxide magnetic nanoparticles for water remediation is a widely investigated research field. To improve the efficacy of such nanomaterials, different synthetic processes and functionalization methods have been developed in the framework of green chemistry to exploit their magnetic properties and adsorption capacity in a sustainable way. In this work, iron oxide magnetic nanoparticles embedded in cross-linked sodium alginate beads designed to clean water from metal ions were magnetically characterized. In particular, the effect of copper adsorption on their magnetic properties was investigated. The magnetic characterization in a DC field of the beads before adsorption showed the presence of a superparamagnetic state at 300 K—a state that was also preserved after copper adsorption. The main differences in terms of magnetic properties before and after Cu²⁺ adsorption were the reduction of the magnetic signal (observed by comparing the saturation magnetization) and a different shape of the blocking temperature distribution obtained by magnetization versus temperature measurements. The evaluation of the reduction in magnetization can be important from the application perspective since it can affect the efficiency of the beads’ removal from the water medium after treatment. Full article

This mini-review emphasizes the potential of biomass-derived materials as sustainable components for next-generation electrochemical energy storage systems. Biomass obtained from abundant and renewable natural resources can be transformed into carbonaceous materials. These materials typically possess hierarchical porosities, adjustable surface functionalities, and inherent heteroatom doping. These physical and chemical characteristics provide the structural and chemical flexibility needed for various electrochemical applications. Additionally, biomass-derived materials offer a cost-effective and eco-friendly alternative to traditional components, promoting green chemistry and circular resource utilization. This review provides a systematic overview of synthesis methods, structural design strategies, and material engineering approaches for their use in lithium-ion batteries (LIBs), lithium–sulfur batteries (LSBs), and supercapacitors (SCs). It also highlights key challenges in these systems, such as the severe volume expansion of anode materials in LIBs and the shuttle effect in LSBs and discusses how biomass-derived carbon can help address these issues. Full article

The development of non-toxic silver nanoparticles (AgNPs) for medical and other diverse applications is steadily increasing. However, this study specifically aims to determine the cytotoxic effects of AgNPs synthesized via a green chemistry approach using aqueous-ethanol and ethyl acetate extracts of Artemisia terrae-albae. The photophysical, morphological, and size distribution characteristics of the synthesized AgNPs are analyzed using UV-Vis spectroscopy and transmission electron microscopy (TEM). A modified Allium cepa assay is employed to evaluate biological responses, including root growth, root number, and mitotic index. In this assay, the cell cycles of onion bulbs are synchronized and pre-incubated at 4 °C for 72 h prior to treatment. This study reveals that the AgNPs synthesized from the ethanol extract exhibit notable stability and higher cytotoxicity activity, with a root length of 0.6 ± 0.13 cm, root number of 16 ± 6.88, and mitotic index of 25.0 ± 2.6. These values are significantly more cytogenotoxic than those observed for the ethyl-acetate-derived nanoparticles, which show a root length of 0.8 ± 0.17 cm, root number of 18 ± 6.27, and mitotic index of 36 ± 3.6. These findings highlight the potential of green-synthesized AgNPs as effective cytotoxic agents, especially those obtained from ethanol extract, possibly due to a greater influence of the quantity of diverse phenolic compounds present in the complex mixtures than in the ethyl acetate extract, which otherwise enhanced their morphology, shape, and size. These, overall, contributed to the biological activity. Full article

Construction and demolition byproducts include substantial amounts of wood panel waste (WPW) that pose environmental challenges. They also create opportunities for sustainable resource recovery. This study investigates the potential of WPW-derived biochar as an efficient adsorbent for phenol removal from aqueous solutions. Biochar was produced via pyrolysis at 450 °C and subsequent activation at 750, 850, and 950 °C. The biochar’s physicochemical properties, including surface area, pore volume, and elemental composition, were characterized using advanced methods, including BET analysis, elemental analysis, and adsorption isotherm analysis. Activated biochar demonstrated up to nine times higher adsorption capacity than raw biochar, with a maximum of 171.9 mg/g at 950 °C under optimal conditions: pH of 6 at 25 °C, initial phenol concentration of 200 mg/L, and biochar dosage of 1 g/L of solution for 48 h. Kinetic and isotherm studies revealed that phenol adsorption followed a pseudo-second-order model and fit the Langmuir isotherm, indicating chemisorption and monolayer adsorption mechanisms. Leaching tests confirmed the biochar’s environmental safety, with heavy metal concentrations well below regulatory limits. Based on these findings, WPW biochar offers a promising, eco-friendly solution for wastewater treatment in line with circular economy and green chemistry principles. Full article

Groundwater is one of the main water sources for consumption, domestic use, agriculture, and tourism in coastal communities. However, high total dissolved solids (TDS) levels in the water (700–2000 mg L⁻¹ TDS) and electrical conductivity (3000–5000 µS cm⁻¹) threaten the health and economic growth opportunities for residents. This research aims to evaluate the performance of a laboratory-scale electrodialysis system as a technology for desalinating brackish water. For this purpose, water samples were collected from real groundwater sources. Batch experiments were conducted with varying operational parameters, such as voltage (2–10 V), feed volume (100–1600 mL), recovery rate (50–80%), and cros-flow velocity (1.3–5.1 cm s⁻¹) to determine the electrodialysis system setup that meets the requirements for drinking water in terms of TDS and energy efficiency. A total specific energy consumption of 1.65 kWh m⁻³, including pumping energy, was achieved at a laboratory scale. The conditions were as follows: flow velocity of 5.14 cm s⁻¹, applied voltage of 6 V, feed volume of 1.6 L, and a water recovery of 66%. Furthermore, increasing the flow velocity and the applied voltage enhanced the desalination kinetics and salt removal. Additionally, the system presented opportunities for scalability. This research aims to evaluate a sustainable membrane-based treatment technology for meeting the growing demand for water resources in coastal communities, particularly in developing countries in South America. Full article

This study reports the development of a sustainable biocatalyst system for free fatty acid (FFA) production from cocoa bean shell (CBS) oil using Burkholderia cepacia lipase (BCL). CBS was explored as both a support material and a reaction substrate. Six immobilized systems were prepared using organic (CBS), inorganic (silica), and hybrid (CBS–silica) supports via physical adsorption or covalent binding. Among them, the covalently immobilized enzyme on CBS (ORG-CB) showed the most balanced performance, achieving a catalytic efficiency (Ke) of 0.063 mM⁻¹·min⁻¹ (18.6% of the free enzyme), broad pH–temperature tolerance, and over 50% activity retention after eight reuse cycles. Thermodynamic analysis confirmed enhanced thermal resistance for ORG-CB (Ed = 32.3 kJ mol⁻¹; ΔH‡ = 29.7 kJ mol⁻¹), while kinetic evaluation revealed that its thermal deactivation occurred faster than for the free enzyme under prolonged heating. In application trials, ORG-CB reached 60.1% FFA conversion from CBS oil, outperforming the free enzyme (49.9%). These findings validate CBS as a dual-function material for enzyme immobilization and valorization of agro-industrial waste. The results also reinforce the impact of immobilization chemistry and support composition on the operational and thermal performance of biocatalysts, contributing to the advancement of green chemistry strategies in enzyme-based processing. Full article

The contamination of water bodies by industrial dyes poses a significant environmental challenge on a global scale. Conventional wastewater treatment methods often suffer from limitations related to high cost, limited efficiency, and potential secondary environmental impacts. Recent advances in photocatalytic technologies have highlighted the potential of metal sulfide-based photocatalysts, particularly those synthesized through environmentally friendly, plant-mediated approaches, as promising alternatives for efficient and sustainable dye degradation. However, despite their promising potential, metal sulfide photocatalysts often suffer from limitations such as photocorrosion, low stability under irradiation, and rapid recombination of charge carriers, which restrict their long-term applicability. In light of these challenges, this review provides a comprehensive examination of the physicochemical characteristics, synthetic strategies, and photocatalytic applications of metal sulfides. Particular emphasis is placed on green synthesis routes employing plant-derived extracts, which offer environmentally benign and sustainable alternatives to conventional methods. Moreover, the review elucidates various modification approaches, most notably, the formation of heterostructures, as viable strategies to enhance photocatalytic efficiency and mitigate the aforementioned drawbacks. The green synthesis of metal sulfides, aligned with the principles of green chemistry, offers a promising route toward the development of sustainable and environmentally friendly water treatment technologies. Full article

Polycyclic aromatic compounds can often be made by a sequence featuring an initial Diels–Alder [4 + 2] cycloaddition reaction, followed by cheletropic extrusion of carbon monoxide. These reactions normally require heating the diene and dieneophile in petrochemical-derived aromatic hydrocarbon solvents, such as xylenes or diphenyl ether. This article summarizes the results of attempts to use renewable solvents in place of those currently in use to prepare pentaphenylbenzene and 1,2,4-triphenyltriphenylene. Dihydrolevoglucosenone, p-cymene, ethyl lactate, diethyl carbonate, and cyclopentyl methyl ether have all been successfully evaluated as renewable solvent alternatives in Diels–Alder/cheletropic reaction sequences. An analysis of the products from the reactions investigated did not show evidence of oxidative degradation of the diene reactants. Furthermore, norbornadien-7-one intermediates were not isolated from any of the reactions tested. Full article

This study aimed to assess the emergence and/or re-emergence of Tick-borne Diseases (TBD) in Portugal by linking the hemoparasite burden in companion animals to vector-borne disease dynamics through a One Health approach. Between 2015 and 2024, 1169 clinically suspected animals with hemoparasite infections, treated at the Hospital Veterinário de Santarém (HVS), underwent serological confirmation for Rickettsia conorii, Babesia canis, Ehrlichia spp., and Haemobartonella spp. A total of 3791 serological tests (3.2 tests per animal) were performed and 437 animals tested positive for at least one of the four hemoparasites under investigation. From 2020 to 2024, tests nearly tripled from 894 to 2883, raising positive cases and prevalence from 29.5% to 39.9%, especially for rickettsiosis and hemobartonellosis, indicating an increased circulation of their vectors. A national vector surveillance initiative identified Hyalomma spp., Rhipicephalus sanguineus, Ixodes ricinus, and Dermacentor sp. as primary tick vectors in Portugal for the hemoparasites mentioned above and for other agents like arbovirus, such as Crimean-Congo Hemorrhagic Fever Virus (CCHFV) and tick-borne encephalitis virus (TBEV). This study found that the vectors responsible for transmitting hemoparasitosis, given the high number of serologically positive cases detected in the HVS, represent an increasing risk for TBD. These findings highlight the relevance of companion animal monitoring as an early-warning component within a One Health surveillance approach. Full article

The exponential increase in electronic waste (e-waste) from end-of-life electrical and electronic equipment presents a growing environmental challenge. E-waste contains high concentrations of rare earth elements (REEs), which are classified as critical raw materials (CRMs). Their removal and recovery from contaminated systems not only mitigate pollution but also support resource sustainability within a circular economy framework. The present study proposed the use of hazelnut shells as a biosorbent to reduce water contamination and recover REEs. The sorption capabilities of this lignocellulosic material were assessed and optimized using the response surface methodology (RSM) combined with a Box–Behnken Design (three factors, three levels). Factors such as pH (4 to 8), salinity (0 to 30), and biosorbent dose (0.25 to 0.75 g/L) were evaluated in a complex mixture containing 9 REEs (Y, La, Ce, Pr, Nd, Eu, Gd, Tb and Dy; equimolar concentration of 1 µmol/L). Salinity was found to be the factor with greater significance for REEs sorption efficiency, followed by water pH and biosorbent dose. At a pH of 7, salinity of 0, biosorbent dose of 0.75 g/L, and a contact time of 48 h, optimal conditions were observed, achieving removals of 100% for Gd and Eu and between 81 and 99% for other REEs. Optimized conditions were also predicted to maximize the REEs concentration in the biosorbent, which allowed us to obtain values (total REEs content of 2.69 mg/g) higher than those in some ores. These results underscore the high potential of this agricultural waste with no relevant commercial value to improve water quality while providing an alternative source of elements of interest for reuse (circular economy). Full article

As eco-friendly processes become central to modern organic synthesis, plant-based materials are emerging as attractive alternatives for both nanoparticle fabrication and catalysis. In this study, we explore the use of clove extract, a natural and renewable resource, for the green synthesis of copper oxide (CuO) nanoparticles and their subsequent application in organic transformations. Clove extract was employed to reduce copper chloride via a simple co-precipitation method under mild conditions, yielding CuO nanoparticles characterized by XRD, FTIR, and SEM-EDX techniques. These nanoparticles were then used as catalysts in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) to afford eugenol-based 1,2,3-triazoles in excellent yields. This dual use of clove extract exemplifies a sustainable approach that merges natural product valorization with efficient catalysis for triazole synthesis. Full article

Narcotics trafficking is a fundamental part of organized crime, posing significant and evolving challenges for forensic investigations. Addressing these challenges requires rapid, precise, and scientifically validated analytical methods for reliable identification of illicit substances. Over the past five years, forensic drug testing has advanced considerably, improving detection of traditional drugs—such as tetrahydrocannabinol, cocaine, heroin, amphetamine-type stimulants, and lysergic acid diethylamide—as well as emerging new psychoactive substances (NPS), including synthetic cannabinoids (e.g., 5F-MDMB-PICA), cathinones (e.g., α-PVP), potent opioids (e.g., carfentanil), designer psychedelics (e.g., 25I-NBOMe), benzodiazepines (e.g., flualprazolam), and dissociatives (e.g., 3-HO-PCP). Current technologies include colorimetric assays, ambient ionization mass spectrometry, and chromatographic methods coupled with various detectors, all enhancing accuracy and precision. Vibrational spectroscopy techniques, like Raman and Fourier transform infrared spectroscopy, have become essential for non-destructive identification. Additionally, new sensors with disposable electrodes and miniaturized transducers allow ultrasensitive on-site detection of drugs and metabolites. Advanced chemometric algorithms extract maximum information from complex data, enabling faster and more reliable identifications. An important emerging trend is the adoption of green analytical methods—including direct analysis, solvent-free extraction, miniaturized instruments, and eco-friendly chromatographic processes—that reduce environmental impact without sacrificing performance. This review provides a comprehensive overview of innovations over the last five years in forensic drug analysis based on the ScienceDirect database and highlights technological trends shaping the future of forensic toxicology. Full article