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Correlative Light and Electron Microscopy Using Frozen Section Obtained Using Cryo-Ultramicrotomy
- Hong-Lim Kim,
- Tae-Ryong Riew,
- Jieun Park,
- Youngchun Lee and
- In-Beom Kim
Immuno-electron microscopy (Immuno-EM) is a powerful tool for identifying molecular targets with ultrastructural details in biological specimens. However, technical barriers, such as the loss of ultrastructural integrity, the decrease in antigenicity...