Search Results (46)

Objectives: This study aimed to characterize the basic structure of sialylated glycopeptide (SCP) from edible bird’s nest, and to explore the intervention effect and mechanism of SCP based on a mouse lung inflammation model induced by lipopolysaccharide (LPS). Methods: C57BL/6 mice were randomly divided into the control group (CON), model group (LPS), EBN group, SCP group, and SA group. Results: The results showed that SCP had the typical structures of polypeptides and carbohydrates. SCP effectively intervened in the lung inflammation response. The number of neutrophils (Neu) in BALF decreased by 41.3%, the level of tumor necrosis factor-α (TNF-α) decreased by 36.4%, and the W/D ratio of lung tissues decreased by 27.2%, effectively preventing pathological changes in lung tissues. A total of 40 differential metabolites such as choline, linolenic acid, and xanthine were screened between the SCP group and the LPS group. These differential metabolites were mainly enriched in the metabolic pathways of glycerophospholipids, alpha-linolenic acid, and purines. Conclusions: The research results support that SCP, as the active substance of edible bird’s nest, can effectively improve lung inflammation, providing theoretical guidance for the development of functional edible bird’s nest products. Full article

Cardiovascular disease (CVD) remains a leading cause of mortality worldwide, with dyslipidemia, obesity, diabetes mellitus, and hypertension being major modifiable risk factors. Functional foods with antioxidant and anti-inflammatory properties have gained attention for their potential for reducing CVD risk. Edible bird’s nest (EBN), a functional food rich in bioactive compounds such as sialic acid, lactoferrin, and glycoproteins, has been shown to exhibit antioxidant and anti-inflammatory effects. This review explores the potential of EBN in mitigating CVD risk factors, focusing on its role in improving lipid profiles, managing obesity, and enhancing glucose metabolism. EBN has been shown to improve the lipid profile by regulating the hepatic cholesterol metabolism and gut–liver axis interactions. Additionally, EBN reduces body weight gain and visceral fat accumulation, improves adipokine regulation, and enhances insulin sensitivity, which may collectively support cardiovascular health. Despite promising findings, clinical evidence remains limited. Future research should focus on clinical trials to validate its efficacy, determine optimal dosages, and assess its long-term safety. Additionally, further studies on EBN’s effects on hypertension and its interaction with conventional therapies could enhance its potential role in CVD prevention and management. Full article

The goal of this study was to determine the composition of olive oils from four North Moroccan provinces (Larache, Chefchaouen, Ouazzane and Tetouan), one of the main productive zones nationwide. For this purpose, we evaluate the quality parameters, phenolic compounds, oxidative stability, fatty acids, sterols, uvaol + erytrodiol, carotenoids and chlorophylls of three varieties (‘Picholine marocaine’, ‘Haouzia’ and ‘Menara’) in three campaigns (2019/2020 to 2021/2022) and in three harvesting periods. Another aim was to research the effect of natural microtalc (NMT) on the compounds of olive oils, and to evaluate whether the addition of microtalc to olive pastes during the malaxation stage influences in the quality of olive oils. From the results, it was observed that industrial yields increase when natural microtalcs were used during the oil production. Considering the quality parameters, the olive oils produced with NMT showed lower values when compared with those obtained without any addition. Also, oils produced with NMT showed a higher content in phenolic compounds as well as a greater oxidative stability. It is worth highlighting that the maximum content in phenolic compounds, adding NMT during the extraction process, was determined in oils obtained from the ‘Picholine marocaine’ variety from Chefchaouen, harvested in the 2019/2020 campaign, with 848.71 mg/kg oil, with a value of oxidative stability of 78.68 h. Full article

Background: Emerging evidence suggests that emotions significantly influence clinical decision-making among healthcare professionals. Given that evidence-based nursing (EBN) relies heavily on clinical reasoning, and emotions play a critical role in shaping its quality, exploring the relationship between emotional competence and EBN is essential. Objective: This scoping review aims to map and synthesize existing knowledge on the relationship between nurses’ emotional competence and EBN, while identifying research methodologies and integration challenges. Methods: Following the Joanna Briggs Institute (JBI) methodology and PRISMA-ScR guidelines, a scoping review was conducted. The search strategy included studies from databases such as Scopus and CINAHL, as well as grey literature. Eligibility criteria included primary and secondary research articles in Portuguese, English, Spanish, and French, published since 1990, focusing on the relationship between emotional competence and EBN in nurses. Data were synthesized thematically. Results: Of 751 publications identified, 11 met the inclusion criteria. Three themes emerged: (1) the relationship between emotional competence and EBN in different healthcare contexts; (2) research methodologies used; and (3) integration challenges and suggestions. Findings suggest that nurses with higher emotional competence are more likely to adopt safer, evidence-based practices, facilitating EBN implementation and improving care quality and safety. Conclusions: The evidence highlights the importance of integrating emotional intelligence and EBN in nursing education and practice. Combined educational programs are recommended to enhance professional safety, performance, and well-being. Future research should further explore this relationship to develop practice models that reconcile emotional competencies with evidence-based nursing. Full article

The present study attempted to investigate the best conditions to use 2-(4-chlorophenyle)-1,4,5-triphenyle-H-imidazole as a corrosion inhibitor of mild steel in a 7% HCl and 20% H₂SO₄ pickling bath mixture, using chemical, electrochemical, and surface response methodologies in a spherical field. For this, a Doehlert matrix and two principal factors of the Pickling Process were examined. An experimental evaluation was carried out using weight loss, electrochemical impedance spectroscopy, and polarization curve measurements. Impedance diagrams and Bode plots for uninhibited and inhibited systems were analyzed and simulated using the Z-view program, the fitted data obtained closely followed the same pattern as the experimental results. This study demonstrates that the 2-(4-chlorophenyle)-1,4,5-triphenyle-H-imidazole compound is an effective inhibitor for mild steel in pickling bath solutions, and corrosion inhibition efficiency increases with increases in inhibitor concentration to attain 93.2% imidazole at 10⁻³ M. This is due to the absorbability of Cl⁻ and SO₄²⁻ present in the pickling bath solution and the synergistic effect between both elements. The response used in the exploitation of the design was the determination of inhibitor efficiency. This was assessed through weight loss measurements and electrochemical studies on samples in the absence and presence of 2-(4-chlorophenyle)-1,4,5-triphenyle-H-imidazole. It has been shown that the compound under investigation is an effective cathodic-type inhibitor of mild steel corrosion in pickling bath mixtures. Therefore, the inhibition efficiency was improved with the concentration of the inhibitor, which depended on the molecular structure. The optimal corrosion inhibition efficiency as a function of variation in 2-(4-chlorophenyle)-1,4,5-triphenyle-H-imidazole concentration and pickling bath temperature was simulated and demonstrated using canonical analysis; the obtained efficiency at 324 K for 6 h was 81.3% for the coded variable and 83.4% for the real variable. The experimental results are based on a real-time system and provide much more precise results than the simulated results. Full article

IMC has been reported to influence embryo implantation negatively in animals including rats. While EBN has been known to have a potential protective effect against reproductive toxicity, there is limited study on the effect of EBN on IMC toxicity in reproduction. This study aimed to ascertain whether pretreatment with a natural substance, Edible Bird’s Nest (EBN), will reduce IMC-induced toxicity in pregnant rats. Thirty Sprague-Dawley rats divided into five equal groups were treated with EBN and IMC as follows: G1 = Control, G2 = IMC (4.33 mg/kg), G3 = IMC + EBN (4.33 mg/kg + 60 mg/kg), G4 = IMC + EBN (4.33 mg/kg + 90 mg/kg), and G5 = IMC + EBN (4.33 mg/kg +120 mg/kg). EBN was administered once daily for 8 weeks while IMC was injected subcutaneously. On day 8 after mating, all rats were sacrificed for blood sampling and embryo implantation rate (EIR) assessment; the uterine tissues were also subjected to immunohistochemical and histological analyses. G5 recorded significantly higher EIR, fertility index, and expression of epidermal growth factor receptor (EGFR) in the uterine section, across stroma cells, the glandular epithelium, and the luminal epithelium compared to control and other groups. IMC-induced inflammatory alterations, endometrial atrophy, vacuolar degeneration, and atrophy were not detected in uterine tissue sections in G4 and G5, with the latter group demonstrating the highest EIR with protective effects on uterine tissues. Thus, EBN supplementation might be of great benefit in guarding the fertility of individuals who depend on IMC for the treatment of chronic inflammatory illness. Full article

Objectives: Our study investigated the effects and mechanisms of edible bird’s nest (EBN) and free sialic acids (SA) on LPS-induced brain inflammation in mice. Methods: The experiment divided the mice into four groups: control group (CON), lipopolysaccharide group (LPS), EBN intervention group (EBN, 200 mg/kg/d in dry EBN), and sialic acid intervention group (SA, dosage was calibrated based on the concentration of sialic acid in EBN). Results: The results showed that LPS caused a decrease followed by upregulation in body weight in female mice, and EBN exhibited renal protective effects. In the Morris water maze, the learning and memory abilities of mice in the LPS group first declined and then recovered. At the same time, the escape latency improved in the EBN and SA groups. In the Open field test, both the EBN and SA groups exhibited anti-anxiety and anti-depressive effects. Immunohistochemistry in the hippocampus showed significant cell damage in the LPS group, while the damage was alleviated in the EBN and SA groups. LPS promoted the expression of TICAM1 and MYD88 in the NF-κB pathway, while both the EBN and SA groups could inhibit the expression of TICAM1. Conclusions: The study has found that both EBN and SA exhibited noteworthy anti-inflammatory effects, indicating that the main active component in EBN that provides neuroprotective effects is SA. The bound SA in EBN confers additional effects, supporting the development of prevention and treatment strategies for brain inflammation. Full article

In order to improve the concealment and security of a point-to-point transparent forwarding satellite communication system, a signal structure based on aperiodic long code spread spectrum is designed in this paper. This structure can achieve reliable signal acquisition without special physical layer synchronization overhead, which can effectively shorten signal transmission time and improve the concealment of communication. In addition, the performance of burst spread spectrum signal acquisition is analyzed in detail by establishing a mathematical model, and the influencing factors and design criteria of the matching filter length for aperiodic long code acquisition are determined. On this basis, a matched filter acquisition method based on high-power clock multiplexing and an adaptive decision threshold design method based on an auxiliary channel are proposed. The above methods effectively reduce hardware complexity and resource consumption caused by long code acquisition, and realize reliable acquisition under the condition of low SNR. The simulation results show that under the condition of Eb/N0 = 3 dB, the transmission efficiency for a 128-symbol burst frame can be increased by 50%, thereby significantly reducing the burst communication time. Furthermore, the acquisition success probability can reach 99.99%. Full article

Background: In recent years, the advancement of computational chemistry has offered new insights into the rational design of molecularly imprinted polymers (MIPs). From this aspect, our study tried to give quantitative parameters for evaluating imprinting efficiency and exploring the formation mechanism of MIPs by combining simulation and experiments. Methods: The pre-polymerization system of sulfadimethoxine (SDM) was investigated using a combination of quantum chemical (QC) calculations and molecular dynamics (MD) simulations. MIPs were prepared on the surface of silica gel by a surface-initiated supplemental activator and reducing agent atom transfer radical polymerization (SI-SARA ATRP). Results: The results of the QC calculations showed that carboxylic monomers exhibited higher bonding energies with template molecules than carboxylic ester monomers. MD simulations confirmed the hydrogen bonding sites predicted by QC calculations. Furthermore, it was observed that only two molecules of monomers could bind up to one molecule of SDM, even when the functional monomer ratio was up to 10. Two quantitative parameters, namely, the effective binding number (EBN) and the maximum hydrogen bond number (HBN_Max), were defined. Higher values of EBN and HBN_Max indicated a higher effective binding efficiency. Hydrogen bond occupancies and RDF analysis were performed to analyze the hydrogen bond formation between the template and the monomer from different perspectives. Furthermore, under the influence of the EBN and collision probability of the template and the monomers, the experimental results show that the optimal molar ratio of template to monomer is 1:3. Conclusions: The method of monomer screening presented in this study can be extended to future investigations of pre-polymerization systems involving different templates and monomers. Full article

To tackle the problem of difficult signal detection and carrier frequency synchronization faced by wireless communication among stations of the multistatic passive detection system in interference environments, an adaptive signal detection and carrier frequency offset (CFO) estimation method based on a virtual array is proposed in this paper. This is a data-aided method that utilizes a training sequence composed of three segments of sub-training sequences with different symbols. This method first uses spatial spectrum estimation to obtain the coarse frequency estimations of interference signals and CFO from virtual array signals constructed from the first two sub-training sequences. Then, beamforming is conducted accordingly on the virtual array signals constructed from the third sub-training sequence to suppress the in-band interferences and protrude the expected signal. Finally, improved performance of signal detection and CFO estimation is obtained with the beamformed signals. Simulation experiments show that a missed detection probability as low as 1 × 10⁻⁴, with a false detection probability of 1 × 10⁻³, can be obtained under a signal-to-interference ratio (SIR) of −10 dB and E_b/N₀ of 1 dB. Moreover, the proposed method can also simultaneously achieve a CFO estimation error that is lower than 3%, with the condition of E_b/N₀ being as low as −5 dB under different SIRs. Simulation results validate the proposed method and demonstrate the promising application prospects of the proposed method in networked passive detection scenarios. Full article

Promising results were recently reported for hierarchical ion-exchange membranes, fabricated by the UV crosslinking of a thin functional coating on a porous substrate, on model NaCl solution demineralization by electrodialysis (ED). Hierarchical anion-exchange membranes (hAEMs) have never been tested with complex solutions to demonstrate their potential use in the biofood industry. The impact of three different crosslinking densities of the ion-exchange coating (EbN-1, EbN-2 and EbN-3) on the performances of whey demineralization by ED was investigated and compared with commercial AMX. The results showed that by increasing the coating crosslinking density, the membrane conductivity decreased, leading to an increase in the global system resistance during whey demineralization (from +28% to +64%). However, 18% sweet whey solutions were successfully treated until 70% demineralization for all membranes. The energy consumption (averaged EbN value of 14.8 vs. 15.1 Wh for AMX) and current efficiency (26.0 vs. 27.4%) were similar to the control. Potential fouling by non-protein nitrogen was detected by ATR-FTIR for hAEMs impacting some membranes properties and ED performances. Overall, EbN-1 obtained results were comparable with the benchmark and can be considered as an alternative membrane for whey demineralization by ED and other applications in the demineralization of complex products from the food industry. Full article

Derived from the denitrifying bacterium Aromatoleum aromaticum EbN1 (Azoarcus sp.), the enzyme S-1-(4-hydroxyphenyl)-ethanol dehydrogenase (S-HPED) belongs to the short-chain dehydrogenase/reductase family. Using research techniques like UV-Vis spectroscopy, dynamic light scattering, thermal-shift assay and HPLC, we investigated the catalytic and structural stability of S-HPED over a wide temperature range and within the pH range of 5.5 to 9.0 under storage and reaction conditions. The relationship between aggregation and inactivation of the enzyme in various pH environments was also examined and interpreted. At pH 9.0, where the enzyme exhibited no aggregation, we characterized thermally induced enzyme inactivation. Through isothermal and multitemperature analysis of inactivation data, we identified and confirmed the first-order inactivation mechanism under these pH conditions and determined the kinetic parameters of the inactivation process. Additionally, we report the positive impact of glucose as an enzyme stabilizer, which slows down the dynamics of S-HPED inactivation over a wide range of pH and temperature and limits enzyme aggregation. Besides characterizing the stability of S-HPED, the enzyme’s catalytic activity and high stereospecificity for 10 prochiral carbonyl compounds were positively verified, thus expanding the spectrum of substrates reduced by S-HPED. Our research contributes to advancing knowledge about the biocatalytic potential of this catalyst. Full article

An initial cross of V. darrowii ‘Johnblue’ (Darrow’s blueberry) × V. vitis-idaea ‘Red Sunset’ (lingonberry) produced more than 30 true intersectional diploid hybrids as confirmed by molecular markers. The most vigorous of these hybrids was extensively evaluated. This hybrid, US 2535-A, was floriferous and morphologically intermediate to the respective parents. Examination of pollen suggested low male fertility. Numerous crosses using the hybrid as a female reflected similarly low fertility and potential crossing barriers. Stylar examination suggested blockage of pollen tube growth in self-pollinations and significantly retarded growth in backcross pollinations. Nonetheless, two confirmed hybrid offspring were produced using the F₁ hybrid as a female in crosses with V. vitis-idaea and V. darrowii, respectively. In a second set of crosses utilizing additional V. darrowii and V. vitis-idaea genotypes, another 23 verified hybrids in seven parental combinations were produced. Hybrids such as the ones presented offer the potential for generating de novo interspecific fruit types in blueberry and/or broadening the adaptation of lingonberry. Full article

This study comprehensively characterizes synthesized phosphate materials, specifically A₂MnP₂O₇ (where A represents Na, K, or Li), utilizing the X-ray diffraction (XRD) and infrared (IR) spectroscopy techniques. The XRD results corroborate the crystalline nature of these compounds, while the IR spectra disclose pivotal structural characteristics, including the bent geometry of the POP bridge. A significant observation is the mismatch of specific IR bands, suggesting a non-centrosymmetric arrangement in the A₂MnP₂O₇ crystal lattice. The synthesized materials were evaluated as corrosion inhibitors for mild steel (MS) in 3 wt.% NaCl. Electrochemical assessments indicate that these materials act as mixed-type inhibitors, demonstrating high inhibition efficiencies (η%), reaching peak values of 88.3% for Na₂MnP₂O₇, 87% for K₂MnP₂O₇, and 86.7% for Li₂MnP₂O₇ at a concentration of 10⁻³ mol/L. The study also elucidates the thermodynamic and kinetic parameters dictating the inhibition phenomena. Additionally, scanning electron microscopy (SEM) was employed to examine the surface morphology of mild steel in the presence of these inhibitors. Full article

This study demonstrates robot technology for harvesting edible bird’s nests within swiftlet houses. A comprehensive manipulator’s movement analysis of harvesting operation with a separating tool is provided for precisely collecting swiftlet nests. A robotic manipulator mounted on a mobile platform with a vision system is also analyzed and evaluated in this study. The actual harvesting or separating the swiftlet nests is performed with visual servo feedback. The manipulator performs the gross motions of separating tools and removing the nests under computer control with velocity and position feedback. The separating principle between the objective nest and wooden frame has been applied to a demonstration removal of nests using a four-degrees-of-freedom manipulator to perform the gross movements of tool. The actual separations using this system are accomplished as fast as the manipulator can be controlled to perform the necessary deceleration and topping at the end of separating. This is typically 2.0 s. This efficiency underscores the system’s capability for swift and precise operation in harvesting an edible bird nest task. Full article