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14 pages, 269 KiB  
Article
Problematic Media Use and Anxiety Symptoms in Adolescents: The Role of Age and Gender
by Inmaculada Concepción Rodríguez-Rojo, Raquel Luengo-González, Cecilia Peñacoba-Puente, Montserrat García-Sastre, Ernesto Espín-Lorite, Daniel Cuesta-Lozano, Ángel Asenjo-Esteve and Concepción Noriega-Matanza
Healthcare 2025, 13(3), 281; https://doi.org/10.3390/healthcare13030281 - 31 Jan 2025
Cited by 1 | Viewed by 1473
Abstract
Background: Adolescence is a critical biopsychosocial adjustment period, with increased susceptibility to problematic media use (PMU) and associated risk-taking behaviors. The aim of the present study consisted of identifying the relationship between PMU (i.e., videogames, mobile phones, internet, and television) and anxiety in [...] Read more.
Background: Adolescence is a critical biopsychosocial adjustment period, with increased susceptibility to problematic media use (PMU) and associated risk-taking behaviors. The aim of the present study consisted of identifying the relationship between PMU (i.e., videogames, mobile phones, internet, and television) and anxiety in adolescents, considering the moderating effect of gender and age. Methods: A descriptive study using a national survey was conducted on a sample of 4034 participants. Results: Significant gender mean differences were found in PMU and anxiety, with large and moderate effect sizes for PMU (videogames) in males (d = 0.86) and anxiety in females (d = 0.67). Additionally, a direct positive relationship between age and anxiety was observed. Furthermore, PMU significantly predicted anxiety after controlling for age and gender in all cases. Gender had a significant and stronger moderating effect on PMU (television) and anxiety for the male subgroup. The moderating effect of age on PMU and anxiety was statistically significant and more pronounced at younger ages. Conclusions: This research demonstrates the association between PMU and anxiety in adolescents, highlighting the need to further explore other moderating factors influencing mental health symptoms beyond age and gender. It is important to emphasize that mental health is a shared responsibility and not solely the domain of mental health professionals. Therefore, initiatives should be promoted to engage educators, parents, and policymakers in addressing this collective challenge. Full article
20 pages, 3875 KiB  
Article
Multi-Objective Power Supply Restoration in Distribution Networks Based on Graph Calculation and Information Collected by Multi-Source Sensors
by Jian Dang, Shaopeng Zhang, Yile Wang, Yunjiang Yan, Rong Jia and Guangyi Liu
Sensors 2025, 25(3), 768; https://doi.org/10.3390/s25030768 - 27 Jan 2025
Cited by 1 | Viewed by 826
Abstract
With the increasing complexity of the distribution network structure, enhancing the efficiency and reliability during fault restoration has become a focal point. Based on the multi-source information collected by traditional sensors, such as CT and PT, and intelligent sensors, such as D-PMU, and [...] Read more.
With the increasing complexity of the distribution network structure, enhancing the efficiency and reliability during fault restoration has become a focal point. Based on the multi-source information collected by traditional sensors, such as CT and PT, and intelligent sensors, such as D-PMU, and the graph calculation model, the fault recovery problem of a multi-objective distribution network is studied. Firstly, a power flow calculation model and operation constraint adaptable to topology changes are proposed under the graph calculation framework. The minimum spanning tree theory is utilized to define the blackout range and recovery path set. Secondly, the intelligent sensor D-PMU is configured to collect fault information to ensure that at least one of any two connected load vertices is configured with D-PMU. Thirdly, a topological evolution model is established that considers repeated primary and secondary transfer in outage areas while exploring possible recovery strategies deeply. Finally, a distribution network in Shaanxi Province is taken as an example to verify the model. The experiment shows that the strategy in this paper dynamically adjusts the recovery strategy through four means—one transfer, one repeat transfer in the outage area, two transfers, and cutting off part of the outage load—and the overall recovery rate is increased by more than 20%. Full article
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14 pages, 2364 KiB  
Article
A Multi-Mode Recognition Method for Broadband Oscillation Based on CS-OMP and Adaptive VMD
by Jinggeng Gao, Honglei Xu, Yong Yang, Xujun Zhang, Xiangde Mao and Haiying Dong
Energies 2024, 17(23), 5821; https://doi.org/10.3390/en17235821 - 21 Nov 2024
Cited by 1 | Viewed by 723
Abstract
Due to the application of power electronics and wind power generation equipment in power systems, broadband oscillation events constantly appear, which makes broadband oscillation difficult to detect due to the limitations of communication bandwidth and the sampling theorem. To ensure the safety and [...] Read more.
Due to the application of power electronics and wind power generation equipment in power systems, broadband oscillation events constantly appear, which makes broadband oscillation difficult to detect due to the limitations of communication bandwidth and the sampling theorem. To ensure the safety and stability of the system, and to detect and recognize the broadband oscillation information timely and accurately, this paper presents a multi-mode recognition method of broadband oscillation based on compressed sensing (CS) and the adaptive Variational Mode Decomposition (VMD) algorithm. Firstly, the high-dimensional oscillation signal data collected by the Phasor Measurement Unit (PMU) is compressed and sampled by a Gaussian random matrix, and the obtained low-dimensional data are uploaded to the main station. Secondly, the orthogonal matching pursuit (OMP) algorithm of the master station is used to reconstruct the low-dimension signal, and the original high-dimension signal data are recovered without losing the main features of the signal. Finally, an adaptive VMD algorithm with energy loss minimization as a threshold is used to decompose the reconstructed signal, and the Intrinsic Mode Function (IMF) components with broadband oscillation information are obtained. By constructing oscillating signals with different frequencies, Gaussian white noise with a signal-to-noise ratio of 10 dB to 30 dB is added successively. After the signal is compressed and reconstructed by the proposed method, the signal-to-noise ratio can reach 18.8221 dB to 40.0794 dB, etc., and the oscillation frequency and amplitude under each signal-to-noise ratio can be accurately identified. The results show that the proposed method not only has good robustness to noise, but also has good denoising effect to noise. By using the simulation measurement model, the original oscillation signal is compressed and reconstructed, and the reconstruction error is 0.1263. The basic characteristics of the signal are restored, and the frequency and amplitude of the oscillation mode are accurately identified, which proves that the method is feasible and accurate. Full article
(This article belongs to the Special Issue Clean and Efficient Use of Energy: 2nd Edition)
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27 pages, 2230 KiB  
Article
Multilevel Distributed Linear State Estimation Integrated with Transmission Network Topology Processing
by Dulip Madurasinghe and Ganesh Kumar Venayagamoorthy
Appl. Sci. 2024, 14(8), 3422; https://doi.org/10.3390/app14083422 - 18 Apr 2024
Cited by 2 | Viewed by 1319
Abstract
State estimation (SE) is an important energy management system application for power system operations. Linear state estimation (LSE) is a variant of SE based on linear relationships between state variables and measurements. LSE estimates system state variables, including bus voltage magnitudes and angles [...] Read more.
State estimation (SE) is an important energy management system application for power system operations. Linear state estimation (LSE) is a variant of SE based on linear relationships between state variables and measurements. LSE estimates system state variables, including bus voltage magnitudes and angles in an electric power transmission network, using a network model derived from the topology processor and measurements. Phasor measurement units (PMUs) enable the implementation of LSE by providing synchronized high-speed measurements. However, as the size of the power system increases, the computational overhead of the state-of-the-art (SOTA) LSE grows exponentially, where the practical implementation of LSE is challenged. This paper presents a distributed linear state estimation (D-LSE) at the substation and area levels using a hierarchical transmission network topology processor (H-TNTP). The proposed substation-level and area-level D-LSE can efficiently and accurately estimate system state variables at the PMU rate, thus enhancing the estimation reliability and efficiency of modern power systems. Network-level LSE has been integrated with H-TNTP based on PMU measurements, thus enhancing the SOTA LSE and providing redundancy to substation-level and area-level D-LSE. The implementations of D-LSE and enhanced LSE have been investigated for two benchmark power systems, a modified two-area four-machine power system and the IEEE 68 bus power system, on a real-time digital simulator. The typical results indicate that the proposed multilevel D-LSE is efficient, resilient, and robust for topology changes, bad data, and noisy measurements compared to the SOTA LSE. Full article
(This article belongs to the Special Issue New Insights into Power System Resilience)
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13 pages, 1720 KiB  
Article
A Fault Location Method for Medium Voltage Distribution Network Based on Ground Fault Transfer Device
by Guanqun Sun, Wang Ma, Shuqing Wei, Defu Cai, Wenzhuo Wang, Chaozheng Xu, Ke Zhang and Yikai Wang
Electronics 2023, 12(23), 4790; https://doi.org/10.3390/electronics12234790 - 26 Nov 2023
Cited by 3 | Viewed by 1787
Abstract
The arc suppression device based on ground fault transfer (GFT) has been preliminarily applied in the medium voltage distribution network (MVDN). An accurate travelling wave (TW) fault location method is proposed to extend the use of the ground fault transfer device. D-PMU is [...] Read more.
The arc suppression device based on ground fault transfer (GFT) has been preliminarily applied in the medium voltage distribution network (MVDN). An accurate travelling wave (TW) fault location method is proposed to extend the use of the ground fault transfer device. D-PMU is used as a travelling wave detection tool to record the transient voltage travelling waves of fault grounding and bus active grounding during arc suppression. Then, the faulty section is identified through the time difference of travelling wave arrival at the upstream and downstream measurement points. On this basis, the fault location equations of the arrival time and distance of the upstream travelling wave are established, and an accurate fault location method based on the arrival time difference of the travelling wave is proposed. The simulation model is established by PSCAD/EMTDC, and the results show that the method has high location accuracy, and the absolute error is less than 30 m. It is not affected by the TW velocity, the fault conditions, or the distributed power sources. Full article
(This article belongs to the Section Power Electronics)
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16 pages, 1842 KiB  
Article
Accurate Fault Location Method Based on Time-Domain Information Estimation for Medium-Voltage Distribution Network
by Guanqun Sun, Rusi Chen, Zheyu Han, Haiguang Liu, Meiyuan Liu, Ke Zhang, Chaozheng Xu and Yikai Wang
Electronics 2023, 12(23), 4733; https://doi.org/10.3390/electronics12234733 - 22 Nov 2023
Cited by 4 | Viewed by 1292
Abstract
The sampling rate of the wide-area synchronous phasor measuring device (D-PMU) in the distribution network is insufficient, and the localization sensitivity of the traditional localization method based on the time-domain Bergeron equation in the distribution network is insufficient. In this paper, an accurate [...] Read more.
The sampling rate of the wide-area synchronous phasor measuring device (D-PMU) in the distribution network is insufficient, and the localization sensitivity of the traditional localization method based on the time-domain Bergeron equation in the distribution network is insufficient. In this paper, an accurate location method of the distribution line grounding fault based on the time-domain’ synchronous information calculation is proposed to solve the problem of limited location accuracy caused by a low sampling rate and the insufficient sensitivity of traditional methods. The method preprocesses the measurement data through low-frequency time-domain signal reconstruction and cubic spline interpolation. The fault current’s different location criterion is constructed by using the voltage and current constraints at the fault point. By calculating the fault current difference at a limited number of calculated points, the accurate fault location under a low sampling rate is realized, which is beneficial to the rapid maintenance of faults and the shortening of the power outage time. Full article
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42 pages, 35310 KiB  
Article
Realistic μPMU Data Generation for Different Real-Time Events in an Unbalanced Distribution Network
by Abdul Haleem Medattil Ibrahim, Madhu Sharma and Vetrivel Subramaniam Rajkumar
Energies 2023, 16(9), 3842; https://doi.org/10.3390/en16093842 - 29 Apr 2023
Cited by 2 | Viewed by 2040
Abstract
Monitoring, protection, and control processes are becoming more complex as distributed energy resources (DERs) penetrate distribution networks (DNs). This is due to the inherent nature of power DNs and the bi-directional flow of current from various sources to the loads. To improve the [...] Read more.
Monitoring, protection, and control processes are becoming more complex as distributed energy resources (DERs) penetrate distribution networks (DNs). This is due to the inherent nature of power DNs and the bi-directional flow of current from various sources to the loads. To improve the system’s situational awareness, the grid dynamics of the entire DER integration processes must be carefully monitored using synchronized high-resolution real-time measurement data from physical devices installed in the DN. μPMUs have been introduced into the DN to help with this. In comparison to traditional measurement devices, μPMUs can measure voltage, current, and their phasors, in addition to frequency and rate of frequency change (ROCOF). In this study, an approach to generating realistic event data for a real utility DN utilizing strategically installed μPMUs is proposed. The method employs an IEEE 34 test feeder with 12 μPMUs installed in strategic locations to generate real-time events-based realistic μPMU data for various situational awareness applications in an unbalanced DN. The node voltages and line currents were used to analyze the various no-fault and fault events. The author generated the data as part of his PhD research project, utilizing his real-time utility grid operation experience to be used for various situational awareness and fault location studies in a real unbalanced DN. The DN was modeled in DIgSILENT PowerFactory (DP) software. The generated realistic μPMU data can be utilized for developing data-driven algorithms for different event-detection, classification and section-identification research works. Full article
(This article belongs to the Special Issue Modeling and Analysis of Active Distribution Networks and Smart Grids)
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16 pages, 2959 KiB  
Article
Multi-Source Information Fusion Technology and Its Application in Smart Distribution Power System
by Xi He, Heng Dong, Wanli Yang and Wei Li
Sustainability 2023, 15(7), 6170; https://doi.org/10.3390/su15076170 - 3 Apr 2023
Cited by 14 | Viewed by 3308
Abstract
Compared to traditional measurement devices, the micro-synchrophasor measurement unit (D-PMU or μPMU) in the distribution power system has great differences in data acquisition frequency, data format, data dimension, time-stamped information, etc. Hence, it is imperative to research the integration mechanism of heterogeneous data [...] Read more.
Compared to traditional measurement devices, the micro-synchrophasor measurement unit (D-PMU or μPMU) in the distribution power system has great differences in data acquisition frequency, data format, data dimension, time-stamped information, etc. Hence, it is imperative to research the integration mechanism of heterogeneous data from multiple sources. Based on the analysis of the current technology of multi-source information fusion, this paper proposes a novel approach, which considers two aspects: the interoperability of multi-source data and the real-time processing of large-scale streaming data. To solve the problem of data interoperability, we have modified the model of D-PMU data and established a unified information model. Meanwhile, an advanced distributed processing technology has been deployed to solve the problem of real-time processing of streaming data. Based on this approach, a smart distribution power system wide-area measurement and control station can be established, and the correctness and practicality of the proposed method are verified by an on-field project. Full article
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16 pages, 1035 KiB  
Review
A Review of Distribution System State Estimation Methods and Their Applications in Power Systems
by Joddumahanthi Vijaychandra, Bugatha Ram Vara Prasad, Vijaya Kumar Darapureddi, Bathina Venkateswara Rao and Łukasz Knypiński
Electronics 2023, 12(3), 603; https://doi.org/10.3390/electronics12030603 - 26 Jan 2023
Cited by 20 | Viewed by 7417
Abstract
This paper summarizes a review of the distribution system state estimation (DSSE) methods, techniques, and their applications in power systems. In recent years, the implementation of a distributed generation has affected the behavior of the distribution networks. In order to improve the performance [...] Read more.
This paper summarizes a review of the distribution system state estimation (DSSE) methods, techniques, and their applications in power systems. In recent years, the implementation of a distributed generation has affected the behavior of the distribution networks. In order to improve the performance of the distribution networks, it is necessary to implement state estimation methods. As transmission networks and distribution networks are not similar due to variations in line parameters, buses, and measuring instruments, transmission state estimation cannot be implemented in distribution state estimation. So, some aspects, such as accuracy, computational time, and efficiency, should be taken into account when designing distribution state estimation methods. In this paper, the traditional methods are reviewed and analyzed with data-driven techniques in order to present the advantages and disadvantages of the various methods. Full article
(This article belongs to the Special Issue Recent Advances in Power Quality Improvement)
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10 pages, 5745 KiB  
Communication
A 5.42~6.28 GHz Type-II PLL with Dead-Zone Programmability and Charge Pump Mismatch Trimming
by Li Kang, Juncai Lv and Xu Cheng
Electronics 2022, 11(24), 4153; https://doi.org/10.3390/electronics11244153 - 13 Dec 2022
Viewed by 1832
Abstract
This paper proposed a 5.42~6.28 GHz type-II phase locked loop (PLL) for the sake of both loop filter switching capability and extensive programmability. An on-chip loop filter is used in conjunction with off-chip one to form a switching filter pair for diverse application [...] Read more.
This paper proposed a 5.42~6.28 GHz type-II phase locked loop (PLL) for the sake of both loop filter switching capability and extensive programmability. An on-chip loop filter is used in conjunction with off-chip one to form a switching filter pair for diverse application scenarios. In order to strike a balance between dead-zone elimination and noise contribution minimization, a 3-bit programmable reset time ranging from 25 ps to 200 ps with a step of 25 ps is brought into PFD (phase frequency detector) design while CP (charge pump) current is programmable from 200 μA to 900 μA with a 100 μA/step digital control. Power management units (PMU) including bandgap and low dropout regulators (LDO) are integrated on-chip with resistor string trimming which effectively counteracts fabrication variations. In addition, a piecewise linear VCO with 3-bit control is designed with a fully digital 6-bit multi-modulus divider (MMD) chain cascaded. The proposed PLL is implemented in a 40-nm bulk CMOS process and the power consumption is 8 mA@1.2 V, in which around 5 mA@1.2 V is consumed by output buffers. The fabricated PLL chip achieves a frequency tuning range of 5.42~6.28 GHz, a phase noise ranging from −107.2~−110.4 dBc/Hz@1 MHz offset from carrier, a reference spur of lower than −70 dBc when on-chip active loop filter bandwidth is set to be around 500 KHz. Its FoM is approximately −176.98~−180.18 dBc/Hz while FoMT is approximately −180.32~−183.52 dBc/Hz@1 MHz offset from carrier. Its most specifications are comparable to or better than most existing literature. Full article
(This article belongs to the Section Microwave and Wireless Communications)
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18 pages, 9972 KiB  
Article
A Multifunctional Battery-Free Bluetooth Low Energy Wireless Sensor Node Remotely Powered by Electromagnetic Wireless Power Transfer in Far-Field
by Alassane Sidibe, Gaël Loubet, Alexandru Takacs and Daniela Dragomirescu
Sensors 2022, 22(11), 4054; https://doi.org/10.3390/s22114054 - 27 May 2022
Cited by 16 | Viewed by 4586
Abstract
This paper presents a multifunctional battery-free wireless sensing node (SN) designed to monitor physical parameters (e.g., temperature, humidity and resistivity) of reinforced concrete. The SN, which is intended to be embedded into a concrete cavity, is autonomous and can be wirelessly powered thanks [...] Read more.
This paper presents a multifunctional battery-free wireless sensing node (SN) designed to monitor physical parameters (e.g., temperature, humidity and resistivity) of reinforced concrete. The SN, which is intended to be embedded into a concrete cavity, is autonomous and can be wirelessly powered thanks to the wireless power transmission technique. Once enough energy is stored in a capacitor, the active components (sensor and transceiver) are supplied with the harvested power. The data from the sensor are then wirelessly transmitted via the Bluetooth Low Energy (BLE) technology in broadcasting mode to a device configured as an observer. The feature of energy harvesting (EH) is achieved thanks to an RF-to-DC converter (a rectifier) optimized for a low power input level. It is based on a voltage doubler topology with SMS7630-005LF Schottky diode optimized at −15 dBm input power and a load of 10 kΩ. The harvested DC power is then managed and boosted by a power management unit (PMU). The proposed system has the advantage of presenting two different power management units (PMUs) and two rectifiers working in different European Industrial, Scientific and Medical (ISM) frequency bands (868 MHz and 2.45 GHz) depending on the available power density. The PMU interfaces a storage capacitor to store the harvested power and then power the active components of the sensing node. The low power digital sensor HD2080 is selected to provide accurate humidity and temperature measurements. Resistivity measurement (not reported in this paper) can also be achieved through a current injection on the concrete probes. For wireless communications, the QN9080 system-on-chip (SoC) was chosen as a BLE transceiver thanks to its attractive features: a small package size and extremely low power consumption. For low power consumption, the SN is configured in broadcasting mode. The measured power consumption of the SN in a deep-sleep mode is 946 µJ for four advertising events (spaced at 250 ms maximum) after the functioning of sensors. It also includes voltage offset cancelling functionality for resistivity measurement. Far-field measurement operated in an anechoic chamber with the most efficient PMU (AEM30940) gives a first charging time of 48 s (with an empty capacitor) and recharge duration of 27 s for a complete measurement and data transmission cycle. Full article
(This article belongs to the Special Issue Wireless Energy Harvesting for the Internet of Things (IoT))
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21 pages, 3207 KiB  
Article
Multi-Objective Optimal D-PMU Placement for Fast, Reliable and High-Precision Observations of Active Distribution Networks
by Yuce Sun, Wei Hu, Xiangyu Kong, Yu Shen and Fan Yang
Appl. Sci. 2022, 12(9), 4677; https://doi.org/10.3390/app12094677 - 6 May 2022
Cited by 8 | Viewed by 2597
Abstract
The distribution-level phasor measurement unit(D-PMU), as a new type of measurement equipment, can support the fast and high-precision observations of active distribution networks. This paper presents a new D-PMU optimal placement method that can be used to reconcile investments with the reliability of [...] Read more.
The distribution-level phasor measurement unit(D-PMU), as a new type of measurement equipment, can support the fast and high-precision observations of active distribution networks. This paper presents a new D-PMU optimal placement method that can be used to reconcile investments with the reliability of high-precision observation systems. The multi-objective optimization model primarily considers the influence of topology changes and N-1 contingencies on observation reliability. Its objectives include minimizing the number of D-PMUs, maximizing network measurement redundancy (NMR) and the average number of observable buses under N-1 contingencies (ANOBC). The model is extended to a form of multi-topology weighting and is combined with zero-injection buses and other measurements. We take the observability of high-weight topology set as the constraint. The model can be solved using the non-dominated sorting genetic algorithm-III (NSGA-III), which gives the set of Pareto optimal solutions. Then, the D-PMU placement order determination method based on the spatial electrical distance is proposed to improve the effect of state estimation faster. IEEE standard systems are taken to verify the effectiveness of the proposed method. With the same number of D-PMUs, this method derives more ANOBC and NMR than other methods. When considering topology changes, the proposed method can use fewer additional D-PMUs to substantially increase the ANOBC and NMR. Full article
(This article belongs to the Topic Power Distribution Systems)
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16 pages, 676 KiB  
Perspective
Smart Grid in China, EU, and the US: State of Implementation
by Paolo Sospiro, Lohith Amarnath, Vincenzo Di Nardo, Giacomo Talluri and Foad H. Gandoman
Energies 2021, 14(18), 5637; https://doi.org/10.3390/en14185637 - 8 Sep 2021
Cited by 22 | Viewed by 6224
Abstract
Depletion of fossil fuel deposits is the main current issue related to the world’s power generation. Renewable energy sources integrated with energy efficiency represent an effective solution. The electrification of end-use coupled with renewable power generation integration is considered as an important tool [...] Read more.
Depletion of fossil fuel deposits is the main current issue related to the world’s power generation. Renewable energy sources integrated with energy efficiency represent an effective solution. The electrification of end-use coupled with renewable power generation integration is considered as an important tool to achieve these tasks. However, the current electric power system does not currently have the suitable features to allow this change. Therefore, in the future, it has to allow two-way direction power flows, communication, and automated controls to fully manage the system and customers. The resulting system is defined as the smart grid. This article analyses the smart grid state of play within China, the US, and the EU, assessing the completion state of each smart grid technology and integrated asset. The analysis related to these countries presented here shows that the smart grid overall state of play in China, the US, and the EU are equal to 18%, 15%, and 13%, respectively, unveiling the need related to further efforts and investments in these countries for the full smart grid development. Full article
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12 pages, 3282 KiB  
Article
D-PMU and 5G-Network-Based Coordination Control Method for Three-Phase Imbalance Mitigation Units in the LVDN
by Mengmeng Xiao, Shaorong Wang and Zia Ullah
Energies 2021, 14(10), 2754; https://doi.org/10.3390/en14102754 - 11 May 2021
Cited by 6 | Viewed by 2226
Abstract
Three-phase imbalance is a long-term issue existing in low-voltage distribution networks (LVDNs), which consequently has an inverse impact on the safe and optimal operation of LVDNs. Recently, the increasing integration of single-phase distributed generations (DGs) and flexible loads has increased the probability of [...] Read more.
Three-phase imbalance is a long-term issue existing in low-voltage distribution networks (LVDNs), which consequently has an inverse impact on the safe and optimal operation of LVDNs. Recently, the increasing integration of single-phase distributed generations (DGs) and flexible loads has increased the probability of imbalance occurrence in LVDNs. To overcome the above challenges, this paper proposes a novel methodology based on the concept of “Active Asymmetry Energy-Absorbing (AAEA)” utilizing loads with a back-to-back converter, denoted as “AAEA Unit” in this paper. AAEA Units are deployed and coordinated to actively absorb asymmetry power among three phases for imbalance mitigation in LVDNs based on the high-precision, high-accuracy, and real-time distribution-level phasor measurement unit (D-PMU) data acquisition system and the 5th generation mobile networks (5G) communication channels. Furthermore, the control scheme of the proposed method includes three control units. Specifically, the positive-sequence control unit is designed to maintain the voltage of the DC-capacitor of the back-to-back converter. Likewise, the negative-sequence and zero-sequence control units are expected to mitigate the imbalanced current components. A simple imbalanced LVDN is modeled and tested in Simulink/Matlab (MathWorks, US). The obtained results demonstrate the effectiveness of the proposed methodology. Full article
(This article belongs to the Section F: Electrical Engineering)
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12 pages, 2322 KiB  
Article
Haplotypes of the Mutated SIRT2 Promoter Contributing to Transcription Factor Binding and Type 2 Diabetes Susceptibility
by Xiao Zheng, Jiajun Li, Jie Sheng, Yang Dai, Yue Wang, Jinbiao Liu and Yao Xu
Genes 2020, 11(5), 569; https://doi.org/10.3390/genes11050569 - 19 May 2020
Cited by 9 | Viewed by 3047
Abstract
Genetic variability is an important causative factor for susceptibility and pathogenesis of type 2 diabetes (T2D). Histone deacetylase, sirtuin 2 (SIRT2), plays regulatory roles in glucose metabolism and insulin sensitivity. However, whether the SIRT2 variants or haplotypes contribute to T2D risk remain to [...] Read more.
Genetic variability is an important causative factor for susceptibility and pathogenesis of type 2 diabetes (T2D). Histone deacetylase, sirtuin 2 (SIRT2), plays regulatory roles in glucose metabolism and insulin sensitivity. However, whether the SIRT2 variants or haplotypes contribute to T2D risk remain to be elucidated. In this study, we first detected three novel polymorphisms (P-MU1, P-MU2, and P-MU3) in the promoter of SIRT2 in the Chinese population. All pairwise sets of the three loci were strongly in linkage disequilibrium. Next, we constructed the haplotype block structure, and found H1-GGC and H2-CCA accounted for the most (total 91.8%) in T2D. The haplotype combination H1-H1-GGGGCC displayed a high risk for T2D (OR = 2.03, 95% CI = 1.12–3.72). By association analysis, we found the individuals carrying H1-H1-GGGGCC had significantly higher fasting plasma glucose and glycated hemoglobin. The haplotype H1-GGC presented a 6.74-fold higher promoter activity than H2-CCA, which was consistent with the correlation results. Furthermore, we clarified the mechanism whereby the C allele of both the P-MU1 and P-MU2 loci disrupted the signal transducer and activator of transcription 1 (STAT1) binding sites, leading to the attenuation of the SIRT2 transcription. Together, these data suggest that the linked haplotype GGC could be considered as a promising marker for T2D diagnosis and therapy assessment. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
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