Search Results (37)

In response to the plastic pollution crisis, bioplastics emerged as a sustainable alternative. However, low degradation rate and abiotic decomposition generate micro- and nanoplastics. These particles enter the food chain, establishing oral intake as a key route of human exposure. This review gathered studies on the biotransformation of bioplastics in the gastrointestinal tract and on their toxicity in human cells and murine models. Most studies focused on polylactic acid particles due to widespread use in food packaging. Under simulated gastrointestinal conditions in vitro, particles were modulated, resulting in cavity and pore formation, fragmentation, lipase competition, protein corona formation, and alterations in the gut microbiota (including Selenomonadaceae, Bifidobacterium, and Prevotellaceae). Also, particle breakdown increases surface area, enhancing interactions with biomolecules and causing higher in vitro and in vivo toxicity. Indeed, pro-inflammatory cytokine secretion, oxidative stress induction, and redox imbalance were found in both models. In mice, alterations in gut microbiota involving Bacillales indirectly mediated hepatotoxicity, leading to uric acid and triglyceride accumulation. Furthermore, microbiota adaptation over time was suggested with an increase in microorganisms and the potential conversion of L-lactic into harmful D-lactic acid. Despite limited studies, this review highlighted that ingested bioplastic-derived micro- and nanoplastics can lead to toxic effects. Full article

Background: During the global outbreak of coronavirus disease 2019 (COVID-19), the Kingdom of Saudi Arabia (KSA) ranked second in terms of the highest rate of confirmed cases among the Arab Gulf countries. This situation significantly impacted its population, economy, and healthcare system, especially the psychological well-being of frontline healthcare workers, including frontline nurses. However, there is lack of studies on this topic, particularly on the experiences of frontline expatriate nurses in the KSA, necessitating the utilization of descriptive phenomenological design. Objective: This study aimed to explore the experiences of frontline expatriate nurses and their influence on psychological well-being while delivering care to patients with COVID-19. Methods: The study employed a qualitative, descriptive phenomenological design that adhered to the key features of Husserl’s phenomenological approach and purposive sampling to select 17 frontline expatriate nurses. They participated in face-to-face semi-structured interviews. Prior to the 17 semi-structured interviews, written consent was obtained from each of the frontline expatriate nurses. The qualitative data collected were analyzed through thematic analysis and rigor was ensured in this qualitative investigation. Results: Two primary themes were identified from the interviews: (1) psychological effects due to fear of contracting the corona virus, which included two sub-themes pertaining to organizational stressors resulting in having anxiety, depression, fear, mental stress, and stigmatization; and (2) resilience to cope with the challenges brought by the pandemic, which was characterized by three sub-themes focusing on the importance of accurate information, presence of family and social support, and maintaining good health. The expatriate status of frontline nurses is a key factor influencing in their psychological well-being and resilience. Conclusions: Findings indicated that the psychological well-being of frontline expatriate nurses was adversely affected during the pandemic while caring for COVID-19 patients. Consequently, targeted interventions aimed at alleviating the negative psychological impacts of the pandemic are urgently needed to bolster the resilience of frontline expatriate nurses in emergency situations such as the COVID-19 crisis to cope with the associated psychological challenges during the peak of the pandemic, particularly among expatriate nurses. Full article

The COVID-19 pandemic represents a major global health crisis, with clinical manifestations ranging from asymptomatic infection to fatal outcomes. While all individuals are susceptible, specific populations, particularly those with pre-existing medical conditions, face a heightened risk of severe disease. This study aimed to assess the prevalence of severe COVID-19 among hospitalized patients with comorbidities in the Central Region of Romania, and to analyze the association between these conditions and mortality. We conducted a retrospective cohort study using data from the Corona Forms platform (2020–2022), encompassing hospitalized cases across three Romanian counties. A total of 1458 patients with confirmed SARS-CoV-2 infection and documented comorbidities were included. Demographic characteristics, comorbid conditions, and hospitalization outcomes were analyzed. The overall mortality rate among comorbid patients was 89.3%. Renal, neurologic, hepatic disease, cardiovascular conditions, obesity, type 2 diabetes mellitus, and cerebrovascular accidents are significant risk factors for death outcomes in the SARS-CoV-2-infected study population. The strength of their association varies, with odds ratios ranging from 25.32 to 1. The findings underscore the critical impact of comorbidities on COVID-19 severity and mortality among the Central Romanian population, emphasizing the necessity of targeted clinical interventions and public health strategies to protect high-risk populations. Full article

Religious leaders are highly influential actors in many societies across the globe. In the singular global crisis brought upon by the COVID-19 pandemic, their perspective on the pandemic itself but also the post-pandemic future is of high relevance. Against this background, we conducted the Religious Leaders’ Perspectives on Corona Survey, a comprehensive survey of 1200 religious leaders globally, in 2020/2021. Its aim was to investigate the role of religious communities and religious leaders during the COVID-19 pandemic. This article provides an in-depth outline and discussion of the survey methodology and the resultant dataset, thereby paving the way for future research using the survey data. Moreover, the first set of key results is highlighted. It emerges that the COVID-19 pandemic was not primarily a health crisis. Rather, in terms of its consequences, COVID-19 had the characteristics of a primarily economic crisis in the Global South and a primarily psychosocial crisis in the Global North. Moreover, the pandemic has had a fundamental impact on religious practice across the globe. This impact, however, seems to be highly unequal between the Global South and North. Religious communities are shown to have had an important role as civil society actors in the pandemic, providing both psychosocial and material support. Regarding the post-pandemic world, religious leaders envision a more equitable society and emphasize the need for environmental sustainability. Full article

The coronavirus crisis hit both the world and national economies hard. By using a structural equation modelling (SEM) approach and microlevel data from the Community Innovation Survey (CIS2020) on a representative sample of 6437 Norwegian firms comprising a set of COVID-19-related questions, this paper explores the role of firms’ innovation capabilities and strategic agility in times of crises. Our main hypothesis is that these two concepts are interrelated. More specifically, this paper investigates the ‘push’ and ‘pull’-mechanisms of the pandemic on firms’ innovation strategies, as well as which firms were most agile, adapted quickly, introduced innovation due to the COVID-19 crisis rapidly and became more effective with respect to their pre-crisis innovation capabilities. The results indicate that both mechanisms were active during the coronavirus crisis, and most of the firms carried out strategic reactions and changed their business operations on along-term basis. However, the results for innovation output and efficiency improvements vary significantly. “Process developers”, “active R&D doers” and “radical innovators” (the firms that are persistent innovators with the highest score on performing in-house R&D continuously and on innovating in the pre-crisis period) are found to be most agile during the pandemic. They had both introduced innovation and improved their efficiency in quick response to COVID-19. However, firms with low innovation capabilities demonstrated poorer performance during the crisis. These results imply that pre-existing innovation capabilities are important for firms’ strategic flexibility during crises and their ability to respond to changes quickly and efficiently. Full article

This article is based on ethnographic research conducted in Kukljica on the island of Ugljan (Croatia) beginning in August 2020 for the purpose of the author’s doctoral thesis. The complexity of initiating research in a new locality was further burdened by the pandemic, which inevitably affected the outset of fieldwork in this case. This article is thus intended to demonstrate how ethnographic research was conducted during the COVID-19 pandemic and present an image of “corona reality“ in the context of a local-scale pilgrimage. Through the example of the author’s research in Kukljica, this article shows how the research community adapted to the prevailing situation, which was characterized by restrictions and the introduction of new rules, and demonstrates the continuity of local religious practice in a global crisis during the COVID-19 pandemic. Full article

The COVID-19 pandemic has led to various challenges in German health care, including pregnancy care. This paper aims to provide an overview of the pandemic-related challenges faced by pregnant women, new mothers, and their families in maternal and newborn care. A literature review was performed by including international literature as well as recommendations of institutions and official stakeholders. These challenges refer to restrictions at all stages of pregnancy, including wearing masks during labour, limitations of a companion of choice during birth, and restrictions of unvaccinated women from attending, e.g., antenatal classes. Compared with the general population, COVID-19 vaccination of pregnant women was recommended later, as pregnant women were initially excluded from clinical trials. Women who gave birth during the COVID-19 pandemic also reported mental health issues. The findings stress the importance of the inclusion of pregnant women in clinical trials. This might also help to overcome vaccine hesitancy among pregnant women and women seeking family planning. Taking the COVID-19 pandemic as an example, one must weigh the changes and restrictions associated with the potential disadvantages for mothers, newborns, and their families in pregnancy care against the measures to control the pandemic. Full article

It is well known that uncertainty and various measures implemented by the government, such as lockdown, social distancing, and travel restrictions during the COVID-19 pandemic, severely impacted low-income households in Bangladesh. This situation forced them to put forward various mechanisms to cope with the devastating situation caused by the pandemic. This paper focuses on the impact of the COVID-19 epidemic on the quality of life (QoL) of low-income households, their survival coping mechanisms, and the impact of the coping mechanisms on their QoL. From 1 October 2021 to 30 December 2021, primary data from 1279 households were collected through online and offline surveys from different divisions of Bangladesh, and were used to analyze the income-generation, transfer, and cost-minimization practices adopted by the households during the pandemic. The Statistical Package for Social Science (SPSS) version 25 was utilized for data analysis. We employed multivariate and regression statistical techniques to achieve the study objectives. The investigation found that QoL declined significantly due to the COVID-19 crisis. The findings also confirmed that coping mechanisms adopted by households varied according to demographic characteristics, and the QoL deteriorated significantly more in those households that adopted more coping mechanisms relative to others, regardless of socio-demographic features. The findings emphasize the importance of recording grounded survey data to track and gather information on the QoL of low-income households during the pandemic, and of constructing evidence-based policy responses. Furthermore, the study contributes to enriching the existing literature on the impact of the corona pandemic, and can serve as a source for potential studies. This study contributes to a clearer picture of the effects of COVID-19 trauma. This survey-based empirical study provides an understanding of the initial micro-level effects of COVID-19 in Bangladesh. This study gives a synopsis of the extent to which Bangladeshi households adopted mechanisms to deal with the COVID-19 crisis and the effects of the adoption of these mechanisms on quality of life. Full article

Our aim was to assess sleep quality in different subgroups of preclinical medical students, and then to identify specific lifestyle factors, academic and social factors as well as Corona virus related factors that were associated with poor sleeping quality and poor psychological health. Study participants were all medical students at King Saud University of Medical Sciences in the first and second years (648 students), and the study was conducted from December 2021 to January 2022. We administered the survey on paper as well as online. We used three types of questionnaires in this study. The first was a self-administered questionnaire, the second was a validated Insomnia Severity Index (ISI) for finding sleeping problems, and the third was a validated DASS 10 for determining Depression, Anxiety, and Stress. A total of 361 pre-clinical medical students consisted of 146 (40.4%) males and 215 (59.5%) females. The majority of the students, 246 (68.1%), were in their second year. Furthermore, in the current study, students who had poor academic performance (15.8%), satisfactory academic performance (21.3%), or good academic performance (30.7%) had significant sleeping problems found (χ² = 19.4; p = 0.001), among them poor academic performance students 21.6%, satisfactory academic performance students (29.3%), and good academic performance students (29.3%) had moderate to severe levelled sleeping problems. Similarly, poor, satisfactory, and good academic performers experienced the highest levels of anxiety (poor = 21.5%; satisfactory = 22.1%; and good = 22.8%); stress (poor = 22.4%; satisfactory = 25.2%; and good = 22.4%); and depression (poor = 40.5%; satisfactory = 40.5%; and good = 11.9%). The majority of students (64.8%) reported that during the pandemic crisis their anxiety levels were high. Additionally, students reported significantly high sleeping issues (χ² = 10.6; p = 0.001) and also serious psychological issues (Anxiety = 34.9 (0.000); Stress = 32.5 (0.000); and Depression = 5.42 (0.01)). There was a high prevalence of sleep issues, anxiety, stress, and depression among the pre-clinical medical students, with significantly higher sleeping disorders, anxiety, stress, and depression levels among those medical students who struggle with their academic performances, poor lifestyle factor, and poor Social and COVID management. Full article

The corona crisis has affected not only the economic sphere, but also the sphere of health, health care, employment, safety, and health protection in the workplace, shopping habits, and future expectations, to which people adapt their decisions in various areas of daily life. The COVID-19 pandemic, called a global health crisis, was an unpredictable risk of global proportions that paralyzed the entire world. The main aim of this paper is to quantify the impacts of the COVID-19 pandemic on the construction sector, which is considered a crucial sector of the Slovak economy, to evaluate changes in the development of key indicators using adequate quantitative methods. First, a sample of 2000 businesses were analyzed using the 12 financial indicators that were chosen. Second, using the non-parametric Friedman test, a more thorough study was carried out with a focus on analyzing the existence of statistically significant variations in the values of computed indicators as a result of changes in the development of key financial ratios. The Bonferroni adjustments were employed to pinpoint the areas of stochastic dominance at the conclusion of the study. A detailed analysis of the calculated financial indicators showed that the arrival of the pandemic had a negative impact on many aspects of business in the construction sector and affected the financial and economic situation of companies in the construction sector of the Slovak Republic. However, due to the fact that this sector is characterized by slower reactions to changes in the economy, the most significant impacts will be even more noticeable in the future. Full article

Respiratory viruses known as coronaviruses infect people and cause death. The multiple crown-like spikes on the virus’s surface give them the name “corona”. The pandemic has resulted in a global health crisis and it is expected that every year we will have to fight against different COVID-19 variants. In this critical situation, the existence of COVID-19 vaccinations provides hope for mankind. Despite severe vaccination campaigns and recommendations from health experts and the government, people have perceptions regarding vaccination risks and share their views and experiences on social media platforms. Social attitudes to these types of vaccinations are influenced by their positive and negative effects. The analysis of such opinions can help to determine social trends and formulate policies to increase vaccination acceptance. This study presents a methodology for sentiment analysis of the global perceptions and perspectives related to COVID-19 vaccinations. The research is performed on five vaccinations that include Sinopharm, Pfizer, Moderna, AstraZeneca, and Sinovac on the Twitter platform extracted using Twitter crawling. To effectively perform this research, tweets datasets are categorized into three groups, i.e., positive, negative and natural. For sentiment classification, different machine learning classifiers are used such as Random Forest (RF), Naive Bayes (NB), Decision Tree (DT), Logistic Regression (LR), and Support Vector Machine (SVM). It should be noted that the Decision tree classifier achieves the highest classification performance in all datasets as compared to the other machine learning algorithms. For COVID-19 Vaccine Tweets with Sentiment Annotation (CVSA), the highest accuracy obtained is 93.0%, for the AstraZeneca vaccine dataset 90.94%, for the Pfizer vaccine dataset 91.07%, 88.01% accuracy for the Moderna vaccine dataset, for the Sinovac vaccine dataset 92.8% accuracy, and 93.87% accuracy for the Sinopharm vaccine dataset, respectively. The quantitative comparisons demonstrate that the proposed research achieves better accuracy as compared to state-of-the-art research. Full article

Previous research has focused mainly on the association between working from home (WFH) and physical activity, establishing that physical activity diminished among people WFH during the COVID-19 pandemic. In our study, we investigated the association between WFH and specifically sports participation (competitive and non-competitive). We theorized that WFH would offer individuals additional opportunities to practice sports during the pandemic. Governmental restrictions at the time constrained opportunities to participate in organized sports and in sports with others. We, therefore, expected sports participation during the pandemic to be largely restricted to individual participation and participation at home or in the public space. By means of descriptive analyses and adjusted analyses of variance (n = 1506), we found positive associations between WFH and various aspects of sports participation. Lower-educated individuals, in particular, seem to be benefiting from WFH related to their sports participation in the public space, and economically deprived individuals also seem to be benefiting from WFH in regard to their sports participation at home. Our findings extend the literature on physical activity and sports participation among people who worked from home during the COVID-19 pandemic while offering implications for policies on WFH, sports opportunities in public space and physical activity-friendly environments. Full article

The corona crisis caused discontinuity within the financial sector, which has further increased the importance of innovation for sustainability and the capability to manage discontinuity. The aim of this research is to investigate how the corona crisis affected the relationship between sustainability-oriented innovation, sustainable entrepreneurial orientation, and absorptive capacity in the financial sector. Empirical research was carried out in the Dutch financial sector during the corona crisis by means of semi-structured interviews with senior managers, semi-structured group interviews with employees, observations, and documentation. The results of this qualitative exploratory case-study research show that the corona crisis has caused discontinuity for the case organization, which has led to an increase in uncertainty and a decrease in risk appetite. However, the degree of proactivity, innovativeness, knowledge adaptation, knowledge acquisition, knowledge exploitation, and knowledge transformation have also increased as a result of the corona crisis. Therefore, the case organization was able to manage discontinuity and realize more sustainability-oriented innovation. Findings seem to indicate that for the case organization, the corona crisis had a predominantly positive effect on (the relationship between) sustainability-oriented innovation, sustainable entrepreneurial orientation, and absorptive capacity. This research has several theoretical and practical implications and contains recommendations for further research and practice. Full article

Background: Little is known about psychiatric patients’ experiences during the COVID-19 pandemic. The purpose of this study was to investigate associations of coping strategies, social support and loneliness with mental health symptoms among these patients. Methods: We recruited 164 patients from Community Mental Health Centers in June–July 2020. Participants responded to an online questionnaire on corona-related questions, Brief Coping Orientation to Problems Experience, Crisis Support Scale, a 3-item Loneliness Scale, and Hopkins Symptom Checklist-25. We used linear regression models to investigate associations between these and symptoms of depression and anxiety. Results: Almost 51% were aged 31–50 years and 77% were females. Forty-six (28%) participants reported worsened overall mental health due to the pandemic. The reported rates of clinical depression and anxiety were 84% and 76%, respectively. Maladaptive coping was independently associated with both depression and anxiety symptoms. Loneliness was independently associated with depression symptoms. Conclusions: Patients in Community Mental Health Centers in Norway reported high rates of depression and anxiety symptoms. Many of them reported worsening of their mental health due to the pandemic, even at a time when COVID-19 infections and restrictive measures were relatively low. Maladaptive coping strategies and loneliness may be possible explanations for more distress. Full article

Background: Stroke is a chronic disease that requires stroke survivors to be supported long-term by their families. This is especially because of the inaccessibility to post-stroke rehabilitation outside hospitals. The Corona Virus Disease 2019 (COVID-19) crisis and the pandemic restrictions in Malaysia are expected to exponentially increase the demand from family caregivers in supporting stroke survivors. Thus, this study aims to explore the burden, experience, and coping mechanism of the family caregivers supporting stroke survivors during the COVID-19 pandemic. Methodology: A phenomenological qualitative study was conducted from November 2020 to June 2021 in Malaysia. A total of 13 respondents were recruited from two public rehabilitation centers in Kota Bharu, Kelantan. In-depth interviews were conducted with the participants. Comprehensive representation of perspectives from the respondents was achieved through purposive sampling. The interviews were conducted in the Kelantanese dialect, recorded, transcribed, and analyzed using thematic analysis. Results: Three themes on burdens and experiences were identified. They were worsening pre-existing issues, emerging new issues, and fewer burdens and challenges. Two themes on coping strategies were also identified. They were problem-focused engagement and emotion-focused engagement. Conclusions: The COVID-19 pandemic has changed the entire system of stroke management. While family caregivers mostly faced the extra burden through different experiences, they also encountered some positive impacts from the pandemic. The integrated healthcare system, especially in the era of digitalization, is an important element to establish the collaborative commitment of multiple stakeholders to compensate burden and sustain the healthcare of stroke survivors during the pandemic. Full article