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30 pages, 5026 KiB  
Article
Integration and Symbiosis: Medievalism in Giulio Aleni’s Translation of Catholic Liturgy in Late Imperial China
by Chen Cui
Religions 2025, 16(8), 1006; https://doi.org/10.3390/rel16081006 (registering DOI) - 2 Aug 2025
Abstract
This essay provides a fine-grained analysis of selected passages of Giulio Aleni (艾儒略 1582–1649)’s translation of Catholic liturgy into classical Chinese in late imperial China. It focuses on the hitherto underexplored relationships between Aleni’s resort to medieval Aristotelianism and Thomism, as well as [...] Read more.
This essay provides a fine-grained analysis of selected passages of Giulio Aleni (艾儒略 1582–1649)’s translation of Catholic liturgy into classical Chinese in late imperial China. It focuses on the hitherto underexplored relationships between Aleni’s resort to medieval Aristotelianism and Thomism, as well as his translation-based introduction of Catholic Eucharistic theology into China. The case studies here revolve around Aleni’s Chinese translation of Aristotelian-Thomistic hylomorphism, with a focus on his interpretation of “anima” (i.e., the soul, which corresponds largely to linghun 靈魂 in Chinese), which is a multifaceted Western concept that pertains simultaneously to Aristotelian-Thomistic philosophy and Eucharistic theology. It is argued that in his overarching project of introducing Western learnings (i.e., 西學) to sixteenth- and seventeenth-century China, Aleni’s attention is centered primarily on the body-soul and form-matter relationship. This is, as understood here, motivated to a great extent by his scholarly awareness that properly informing Chinese Catholics of the Aristotelian-Thomistic underpinning of Western metaphysics enacts an indispensable role in introducing Catholic liturgy into China, notably the mystery of the Eucharist and Transubstantiation that would not have been effectively introduced to China without having the Western philosophical underpinnings already made available to Chinese intellectuals. Aleni’s use of medieval European cultural legacy thus requires more in-depth analysis vis-à-vis his translational poetics in China. Accordingly, the intellectual and liturgical knowledge in Aleni’s Chinese œuvres shall be investigated associatively, and the medievalism embodied by Aleni offers a valid entry point and productive critical prism. Full article
(This article belongs to the Special Issue Studies on Medieval Liturgy and Ritual)
13 pages, 739 KiB  
Article
Improved Precision of COPD Exacerbation Detection in Night-Time Cough Monitoring
by Albertus C. den Brinker, Susannah Thackray-Nocera, Michael G. Crooks and Alyn H. Morice
J. Pers. Med. 2025, 15(8), 349; https://doi.org/10.3390/jpm15080349 (registering DOI) - 2 Aug 2025
Abstract
Background/Objectives: Targeting individuals with certain characteristics provides improved precision in many healthcare applications. An alert mechanism for COPD exacerbations has recently been validated. It has been argued that its efficacy improves considerably with stratification. This paper provides an in-depth analysis of the cough [...] Read more.
Background/Objectives: Targeting individuals with certain characteristics provides improved precision in many healthcare applications. An alert mechanism for COPD exacerbations has recently been validated. It has been argued that its efficacy improves considerably with stratification. This paper provides an in-depth analysis of the cough data of the stratified cohort to identify options for and the feasibility of improved precision in the alert mechanism for the intended patient group. Methods: The alert system was extended using a system complementary to the existing one to accommodate observed rapid changes in cough trends. The designed system was tested in a post hoc analysis of the data. The trend data were inspected to consider their meaningfulness for patients and caregivers. Results: While stratification was effective in reducing misses, the augmented alert system improved the sensitivity and number of early alerts for the acute exacerbation of COPD (AE-COPD). The combination of stratification and the augmented mechanism led to sensitivity of 86%, with a false alert rate in the order of 1.5 per year in the target group. The alert system is rule-based, operating on interpretable signals that may provide patients or their caregivers with better insights into the respiratory condition. Conclusions: The augmented alert system operating based on cough trends has the promise of increased precision in detecting AE-COPD in the target group. Since the design and testing of the augmented system were based on the same data, the system needs to be validated. Signals within the alert system are potentially useful for improved self-management in the target group. Full article
(This article belongs to the Section Personalized Therapy and Drug Delivery)
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20 pages, 392 KiB  
Article
Johannes Althusius: The First Federalist in Early Modern Times
by Lingkai Kong
Histories 2025, 5(3), 35; https://doi.org/10.3390/histories5030035 (registering DOI) - 2 Aug 2025
Abstract
Johannes Althusius (1563–1638) was a pioneer of early modern federalism. Opposing Jean Bodin’s theory of absolute sovereignty, his theory, centered on association and symbiosis, laid the groundwork for later concepts such as associationalism, consociationalism, and the principle of subsidiarity. While his ideas have [...] Read more.
Johannes Althusius (1563–1638) was a pioneer of early modern federalism. Opposing Jean Bodin’s theory of absolute sovereignty, his theory, centered on association and symbiosis, laid the groundwork for later concepts such as associationalism, consociationalism, and the principle of subsidiarity. While his ideas have been rediscovered and reinterpreted by scholars since the 20th century, systematic research on his federalist framework, especially contrasting it with rival theories of that time, remains insufficient. This article addresses this research gap by systematically exploring Althusius’s federalism. It argues that Althusius’s covenant-based, multi-level associational/federal framework provided a counter-theory to the concept of absolute sovereignty. Systematically studying his federalism not only helps to restore his federalist ideas to their rightful place in the history of federalist thought, but also provides insights for contemporary governance paradigms struggling with modern pluralism. Full article
(This article belongs to the Section Political, Institutional, and Economy History)
34 pages, 1227 KiB  
Review
Beyond Cutting: CRISPR-Driven Synthetic Biology Toolkit for Next-Generation Microalgal Metabolic Engineering
by Limin Yang and Qian Lu
Int. J. Mol. Sci. 2025, 26(15), 7470; https://doi.org/10.3390/ijms26157470 (registering DOI) - 2 Aug 2025
Abstract
Microalgae, with their unparalleled capabilities for sunlight-driven growth, CO2 fixation, and synthesis of diverse high-value compounds, represent sustainable cell factories for a circular bioeconomy. However, industrial deployment has been hindered by biological constraints and the inadequacy of conventional genetic tools. The advent [...] Read more.
Microalgae, with their unparalleled capabilities for sunlight-driven growth, CO2 fixation, and synthesis of diverse high-value compounds, represent sustainable cell factories for a circular bioeconomy. However, industrial deployment has been hindered by biological constraints and the inadequacy of conventional genetic tools. The advent of CRISPR-Cas systems initially provided precise gene editing via targeted DNA cleavage. This review argues that the true transformative potential lies in moving decisively beyond cutting to harness CRISPR as a versatile synthetic biology “Swiss Army Knife”. We synthesize the rapid evolution of CRISPR-derived tools—including transcriptional modulators (CRISPRa/i), epigenome editors, base/prime editors, multiplexed systems, and biosensor-integrated logic gates—and their revolutionary applications in microalgal engineering. These tools enable tunable gene expression, stable epigenetic reprogramming, DSB-free nucleotide-level precision editing, coordinated rewiring of complex metabolic networks, and dynamic, autonomous control in response to environmental cues. We critically evaluate their deployment to enhance photosynthesis, boost lipid/biofuel production, engineer high-value compound pathways (carotenoids, PUFAs, proteins), improve stress resilience, and optimize carbon utilization. Persistent challenges—species-specific tool optimization, delivery efficiency, genetic stability, scalability, and biosafety—are analyzed, alongside emerging solutions and future directions integrating AI, automation, and multi-omics. The strategic integration of this CRISPR toolkit unlocks the potential to engineer robust, high-productivity microalgal cell factories, finally realizing their promise as sustainable platforms for next-generation biomanufacturing. Full article
(This article belongs to the Special Issue Developing Methods and Molecular Basis in Plant Biotechnology)
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21 pages, 258 KiB  
Article
Maraimalai Adigal: How to Understand His Reform of Tamil Shaivism?
by Martin Fárek and Arvind S. Kaushik
Religions 2025, 16(8), 1004; https://doi.org/10.3390/rel16081004 (registering DOI) - 1 Aug 2025
Abstract
Although there is growing agreement between scholars about the crucial role of Maraimalai Adigal in the early stage of the Tamil nationalist movement, the state of current understanding of this “religious phase of Tamil nationalism” is far from satisfactory. Authors of this article [...] Read more.
Although there is growing agreement between scholars about the crucial role of Maraimalai Adigal in the early stage of the Tamil nationalist movement, the state of current understanding of this “religious phase of Tamil nationalism” is far from satisfactory. Authors of this article focused on three important claims in the currently accepted view on the character and goals of Adigal’s religious reform. The first stance portrays his efforts for purification of the Tamil language from foreign influences as “anti-Aryan” and “anti-Sanskritic.” The second claim describes the reformer’s efforts as a move from polytheism to “Shaiva monotheism”, and builds on ideas of the early Orientalists and Christian missionaries in India who formulated the “Sanskritic hegemony” thesis. As an assumption running through the debates about Adigal’s reforms, there is conviction that the Tamil intellectual basically accepted the crystallizing Aryan Invasion Theory as true description of both Ancient India and roots of the social problems in Tamilnadu of his times. In their thorough analysis of Adigal’s work and scholarly debates, authors of this article disclose the role of unexamined assumption about religious competition being the main form of cultural encounters in India, and argue for very different understanding of Adigal’s efforts to revive Shaivism. Full article
12 pages, 230 KiB  
Article
Islamic Modernity and the Question of Secularism: Revisiting the Political Thought of Jamāl al-Dīn al-Afghānī
by Fiona Fu and Jan Gresil Kahambing
Religions 2025, 16(8), 1003; https://doi.org/10.3390/rel16081003 (registering DOI) - 1 Aug 2025
Abstract
This article explores Jamāl al-Dīn al-Afghānī’s political thought in relation to modern debates on secularism and Islamic reform. While often invoked by Islamist thinkers to support their anti-secular stance, al-Afghānī’s reflections on reason, religion, and constitutional politics show that he engaged with modernity [...] Read more.
This article explores Jamāl al-Dīn al-Afghānī’s political thought in relation to modern debates on secularism and Islamic reform. While often invoked by Islamist thinkers to support their anti-secular stance, al-Afghānī’s reflections on reason, religion, and constitutional politics show that he engaged with modernity in a more nuanced way than is commonly recognized. This article examines al-Afghānī’s writings and their reception. It argues that his thought was not about choosing a side between religion and secularism. Instead, his thought is better understood as a pragmatic anti-colonial strategy aimed at the revival of Muslim civilization. This reframing challenges the widely cited genealogical narrative that links him to later Islamists. His attempt to reconcile religious traditions with the imperative for reform provides valuable insights into the responses of Muslim reformers to modernity—insights that remain highly relevant today. Full article
29 pages, 1125 KiB  
Article
Orchestrating Power: The Cultural–Institutional Nexus and the Rise of Digital Innovation Ecosystems in Great Power Rivalry
by Deganit Paikowsky, Dmitry Payson and Yaacov Falkov
Systems 2025, 13(8), 643; https://doi.org/10.3390/systems13080643 (registering DOI) - 1 Aug 2025
Abstract
This article examines how digital innovation ecosystems have emerged as strategic institutions of power in contemporary world politics. It argues that, unlike Cold War technological rivalries driven by centralized, state-led control, today’s digital competition depends on states’ capacity to orchestrate scalable, multistakeholder ecosystems. [...] Read more.
This article examines how digital innovation ecosystems have emerged as strategic institutions of power in contemporary world politics. It argues that, unlike Cold War technological rivalries driven by centralized, state-led control, today’s digital competition depends on states’ capacity to orchestrate scalable, multistakeholder ecosystems. Using a cultural–institutional framework, we explain how differences in strategic culture and institutional governance impact the ecosystem’s vitality and performance. A qualitative comparative analysis of the United States, China, and Russia reveals that constructive orchestration, aligning state institutions with generative, commercial-to-national innovation flows, enhances digital leadership, whereas rigid, obstructive governance limits it. This highlights ecosystem governance as a critical dimension of statecraft in the digital age. The findings underscore that the positions of great powers in the global technological hierarchy depend not only on resources or capabilities but also on the effectiveness of ecosystem governance as an evolving instrument of geopolitical power. Full article
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28 pages, 352 KiB  
Article
Algorithm Power and Legal Boundaries: Rights Conflicts and Governance Responses in the Era of Artificial Intelligence
by Jinghui He and Zhenyang Zhang
Laws 2025, 14(4), 54; https://doi.org/10.3390/laws14040054 (registering DOI) - 31 Jul 2025
Abstract
This study explores the challenges and theoretical transformations that the widespread application of AI technology in social governance brings to the protection of citizens’ fundamental rights. By examining typical cases in judicial assistance, technology-enabled law enforcement, and welfare supervision, it explains how AI [...] Read more.
This study explores the challenges and theoretical transformations that the widespread application of AI technology in social governance brings to the protection of citizens’ fundamental rights. By examining typical cases in judicial assistance, technology-enabled law enforcement, and welfare supervision, it explains how AI characteristics such as algorithmic opacity, data bias, and automated decision-making affect fundamental rights including due process, equal protection, and privacy. The article traces the historical evolution of privacy theory from physical space protection to informational self-determination and further to modern data rights, pointing out the inadequacy of traditional rights-protection paradigms in addressing the characteristics of AI technology. Through analyzing AI-governance models in the European Union, the United States, Northeast Asia, and international organizations, it demonstrates diverse governance approaches ranging from systematic risk regulation to decentralized industry regulation. With a special focus on China, the article analyzes the special challenges faced in AI governance and proposes specific recommendations for improving AI-governance paths. The article argues that only within the track of the rule of law, through continuous theoretical innovation, institutional construction, and international cooperation, can AI technology development be ensured to serve human dignity, freedom, and fair justice. Full article
11 pages, 226 KiB  
Entry
Gender and Digital Technologies
by Eduarda Ferreira and Maria João Silva
Encyclopedia 2025, 5(3), 111; https://doi.org/10.3390/encyclopedia5030111 - 31 Jul 2025
Viewed by 32
Definition
This entry explores the multifaceted intersections of gender and digital technologies, offering a comprehensive analysis of how structural inequalities are reproduced, contested, and transformed in digital contexts. It is structured into six interrelated sections that collectively address key dimensions of gendered digital contexts. [...] Read more.
This entry explores the multifaceted intersections of gender and digital technologies, offering a comprehensive analysis of how structural inequalities are reproduced, contested, and transformed in digital contexts. It is structured into six interrelated sections that collectively address key dimensions of gendered digital contexts. It begins by addressing the gender digital divide, particularly in the Global South, emphasizing disparities in access, literacy, and sociocultural constraints. The second section examines gendered labor in the tech industry, highlighting persistent inequalities in Science, Technology, Engineering, and Mathematics (STEM) education, employment, and platform-based work. The third part focuses on gender representation in digital spaces, revealing how algorithmic and platform design perpetuate biases. The fourth section discusses gender bias in AI and disinformation, underscoring the systemic nature of digital inequalities. This is followed by an analysis of online gender-based violence, particularly its impact on marginalized communities and participation in digital life. The final section considers the potentials and limitations of digital activism in advancing gender justice. These sections collectively argue for an intersectional, inclusive, and justice-oriented approach to technology policy and design, calling for coordinated global efforts to create equitable digital futures. Full article
(This article belongs to the Collection Encyclopedia of Social Sciences)
6 pages, 198 KiB  
Opinion
Relation Between Diffusion Equations and Boundary Conditions in Bounded Systems
by Fabio Sattin and Dominique Franck Escande
Foundations 2025, 5(3), 26; https://doi.org/10.3390/foundations5030026 (registering DOI) - 31 Jul 2025
Viewed by 44
Abstract
Differential equations need boundary conditions (BCs) for their solution. It is widely acknowledged that differential equations and BCs are representative of independent physical processes, and no correlations between them are required. Two recent studies by Hilhorst, Chung et al. argue instead that, in [...] Read more.
Differential equations need boundary conditions (BCs) for their solution. It is widely acknowledged that differential equations and BCs are representative of independent physical processes, and no correlations between them are required. Two recent studies by Hilhorst, Chung et al. argue instead that, in the specific case of diffusion equations (DEs) in bounded systems, BCs are uniquely constrained by the form of transport coefficients. In this paper, we revisit how DEs emerge as fluid limits out of a picture of stochastic transport. We point out their limits of validity and argue that, in most physical systems, BCs and DEs are actually uncorrelated by virtue of the failure of diffusive approximation near the system’s boundaries. When, instead, the diffusive approximation holds everywhere, we show that the correct chain of reasoning goes in the direction opposite to that conjectured by Hilhorst and Chung: it is the choice of the BCs that determines the form of the DE in the surroundings of the boundary. Full article
(This article belongs to the Section Physical Sciences)
23 pages, 1461 KiB  
Article
Interfacing Programming Language Semantics and Pragmatics: What Does “Hello, World” Mean?
by Warren Sack
Philosophies 2025, 10(4), 86; https://doi.org/10.3390/philosophies10040086 (registering DOI) - 31 Jul 2025
Viewed by 44
Abstract
In 1978, Brian Kernighan and Dennis Ritchie insisted that the first program to write in a new language is one to print the words “hello, world.” From then until now, “hello, world” has frequently been the first exercise in introductory programming courses. On [...] Read more.
In 1978, Brian Kernighan and Dennis Ritchie insisted that the first program to write in a new language is one to print the words “hello, world.” From then until now, “hello, world” has frequently been the first exercise in introductory programming courses. On one hand, this does seem like a good first program because it makes something familiar—a greeting—appear on the screen. On the other hand, it is extremely strange. How can it be understood as a greeting? Who is greeting whom? Unfortunately, the bulk of formal means for defining programming languages provides very little help for assigning a meaning to the “hello, world” program. It is argued that the weakness of older theories and methods of programming language semantics is due to the historical, disciplinary segregation (in logic, semiotics, and linguistics) of semantics as a study apart from syntax and pragmatics. Drawing from both more recent work in programming language semantics that addresses side effects and on speech-act-based programming language design, this paper proposes a possible reintegration of semantics and pragmatics in order to better define the meaning of “hello, world” and the programming languages used to produce speech acts more generally. Full article
(This article belongs to the Special Issue Semantics and Computation)
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13 pages, 213 KiB  
Article
From Skepticism to Story: Reclaiming the Bible’s Metanarrative for Postmodern Audiences
by Bob C. Greene
Religions 2025, 16(8), 996; https://doi.org/10.3390/rel16080996 (registering DOI) - 31 Jul 2025
Viewed by 178
Abstract
This article examines the epistemological and homiletical implications of postmodernity for Christian preaching. It addresses the communicative crisis introduced by postmodern skepticism toward metanarratives. It proposes a constructive theological response through the re-articulation of the gospel as a coherent, storied, and transformative metanarrative. [...] Read more.
This article examines the epistemological and homiletical implications of postmodernity for Christian preaching. It addresses the communicative crisis introduced by postmodern skepticism toward metanarratives. It proposes a constructive theological response through the re-articulation of the gospel as a coherent, storied, and transformative metanarrative. Drawing on interdisciplinary scholarship in theology, homiletics, epistemology, and cultural theory, this study argues that a thoughtful engagement with postmodern critique can serve as a catalytic force for ecclesial renewal. The article advocates for a homiletic method that re-engages Scripture’s narrative form while emphasizing relational epistemology, incarnational witness, and contextual sensitivity. By utilizing narrative theology, post-critical epistemologies, and performative models of preaching, this study proposes a recalibrated approach to gospel proclamation, adapted for fragmented and skeptical audiences, while safeguarding theological orthodoxy. Full article
11 pages, 226 KiB  
Article
“Setting the Bible out of the Question”—Pursuing Justice: The (Non) Use of Scripture in John Wesley’s Antislavery Argument and Its Relevance for the Contemporary Pursuit of Justice
by David Nugent Field and Wessel Bentley
Religions 2025, 16(8), 994; https://doi.org/10.3390/rel16080994 - 30 Jul 2025
Viewed by 235
Abstract
One of the core sources for Christian justification or critique of social justice matters is the Bible. One would think that a leading historic Christian figure, like John Wesley, whose theology was closely bound to biblical interpretation, would have used the Bible extensively [...] Read more.
One of the core sources for Christian justification or critique of social justice matters is the Bible. One would think that a leading historic Christian figure, like John Wesley, whose theology was closely bound to biblical interpretation, would have used the Bible extensively to argue against an important matter such as (anti-)slavery. However, we find that his argument lacks his usual biblical-centeredness. This article explores this phenomenon and attempts to understand Wesley’s reasoning and argument in light of his limited use of scripture in this instance. Full article
(This article belongs to the Section Religions and Theologies)
16 pages, 235 KiB  
Article
Populist Radical Right: Illiberal Erosion or Liberal Decay? Assessing Theoretical Explanations in the Wake of the 2024 European Parliament Election
by Alfonso A. López-Rodríguez and Jesus M. Benitez-Baleato
Societies 2025, 15(8), 211; https://doi.org/10.3390/soc15080211 - 30 Jul 2025
Viewed by 253
Abstract
This article identifies the structural factors underlying the rise of the Populist Radical Right (PRR) in Europe and evaluates its implications for liberal democracies. Our research finds that the emergence of the PRR is driven by the decay of democratic institutions resulting from [...] Read more.
This article identifies the structural factors underlying the rise of the Populist Radical Right (PRR) in Europe and evaluates its implications for liberal democracies. Our research finds that the emergence of the PRR is driven by the decay of democratic institutions resulting from the neoliberal globalization that was catalyzed by the collapse of the Soviet Union. We argue that the electoral success of the PRR lies in its capacity to use emotionally charged, single-issue narratives that resonate with the political demands of orphaned electorates, who engage in protest voting to express their frustrated expectations. Far from being an ephemeral phenomenon, we show that the PRR reflects structural transformations of the liberal political architecture, and is capable to further eroding democratic institutions by procedurally adopting liberal norms as a means to undermine them. A critical reassessment of the liberal perspective is necessary to address the dysfunctions of democratic institutions. Full article
22 pages, 274 KiB  
Article
The Cosmos as a World City: A Hylomorphic Foundation for Civic Renewal
by William M. R. Simpson
Religions 2025, 16(8), 991; https://doi.org/10.3390/rel16080991 - 30 Jul 2025
Viewed by 228
Abstract
This paper contends that the West’s civic crisis is, at root, a cosmological crisis: civic renewal requires metaphysical repair. It is insufficient to endorse virtue ethics and demand civic virtues without a deeper account of reality that can sustain them. What is needed [...] Read more.
This paper contends that the West’s civic crisis is, at root, a cosmological crisis: civic renewal requires metaphysical repair. It is insufficient to endorse virtue ethics and demand civic virtues without a deeper account of reality that can sustain them. What is needed is a cosmology—one informed by contemporary science—in which nature, personhood, and political community are meaningfully situated within an ordered whole. Drawing on the Platonic isomorphism between soul, city, and cosmos, I outline a hylomorphic framework with the potential to integrate key elements of neo-Aristotelian, Stoic, and Thomist metaphysics with developments in contemporary physics. Against the dominant atomistic and holistic paradigms, I argue that hylomorphism offers a more adequate account of personhood, the polis, and the cosmos itself as an intelligible whole. Full article
(This article belongs to the Special Issue Aquinas and the Sciences: Exploring the Past, Present, and Future)
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