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19 pages, 1709 KB  
Article
Advanced Vector Extensions 512 Acceleration of LSH and LEA-GCM
by Seung-Won Lee, Min-Ho Song, Ha-Gyeong Kim, Ui-Jae Kim, Si-Woo Eum and Hwa-Jeong Seo
Appl. Sci. 2026, 16(14), 6846; https://doi.org/10.3390/app16146846 - 8 Jul 2026
Viewed by 252
Abstract
This paper presents high-performance Advanced Vector Extensions 512 (AVX-512) implementations of two Korean standard cryptographic algorithms: the Lightweight Secure Hash (LSH) function and Lightweight Encryption Algorithm–Galois/Counter Mode (LEA-GCM) authenticated encryption. For LSH, we apply three optimization strategies: single-message processing using AVX-512 512-bit vector [...] Read more.
This paper presents high-performance Advanced Vector Extensions 512 (AVX-512) implementations of two Korean standard cryptographic algorithms: the Lightweight Secure Hash (LSH) function and Lightweight Encryption Algorithm–Galois/Counter Mode (LEA-GCM) authenticated encryption. For LSH, we apply three optimization strategies: single-message processing using AVX-512 512-bit vector registers, dual-message parallel processing through register interleaving, and multi-core parallelization using a dynamic queue-based pthread thread pool. For LEA-GCM, we propose an end-to-end optimization that replaces scalar counter-mode (CTR) encryption with 16-block AVX-512 parallel processing and Streaming SIMD Extensions(SSE)-based Galois Hash (GHASH) authentication with VPCLMULQDQ-based four-block parallel processing. Performance evaluation on an Intel Core i7-1165G7 (Tiger Lake) processor shows that LSH-256 achieves an average of 1.16× throughput improvement and LSH-512 achieves an average of 1.61× improvement over the Korea Internet and Security Agency (KISA) AVX2 reference implementation. Dual-message interleaving achieves an average superlinear speedup of 2.28×, driven by instruction-level parallelism (ILP), and the thread pool delivers speedups of 3.73× to 5.13× across eight logical cores (four physical cores with hyperthreading). The optimized LEA-GCM implementation achieves a 3.26× throughput improvement over the KISA SSE-based reference and a 12.1× improvement over the pure software implementation for 4096-byte inputs, with correctness verified against KISA official test vectors. Full article
(This article belongs to the Special Issue Recent Advances in Secure Software Engineering)
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36 pages, 2534 KB  
Article
A Lightweight Key Agreement Protocol for V2X Communications Based on Kyber and Saber
by Yinfei Dai, Qi Wang, Xiao Song and Shaoqiang Wang
Sensors 2025, 25(22), 6938; https://doi.org/10.3390/s25226938 - 13 Nov 2025
Cited by 4 | Viewed by 1900
Abstract
This paper proposes a post-quantum secure key agreement protocol tailored for vehicular networks (V2X), addressing the dual challenges of quantum resistance and lightweight deployment. The hybrid scheme integrates two lattice-based Key Encapsulation Mechanisms (KEMs)—Kyber and Saber—to construct a dual-path handshake framework that enhances [...] Read more.
This paper proposes a post-quantum secure key agreement protocol tailored for vehicular networks (V2X), addressing the dual challenges of quantum resistance and lightweight deployment. The hybrid scheme integrates two lattice-based Key Encapsulation Mechanisms (KEMs)—Kyber and Saber—to construct a dual-path handshake framework that enhances cryptographic redundancy and ensures robustness against quantum attacks. The protocol achieves secure and authenticated key exchange through RSU public-key broadcasting, OBU dual-path encapsulation, and session-key derivation using HMAC and timestamps. To support efficient execution in embedded vehicular environments, several algorithm-level optimizations are incorporated, including Number Theoretic Transform (NTT) acceleration for Kyber, AVX2-based parallelism for Saber, and integer inner-product techniques to minimize computational overhead. Experimental validation on a Veins + SUMO vehicular simulation platform demonstrates that the proposed protocol reduces handshake latency by nearly 60% compared with RSA, achieves delay performance comparable to ECDH, and lowers total resource consumption by around 40%. These results confirm that the Kyber + Saber hybrid protocol provides a practical, scalable, and quantum-resistant solution for secure V2X communication in dynamic, resource-constrained, and latency-sensitive environments. Full article
(This article belongs to the Section Vehicular Sensing)
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26 pages, 1099 KB  
Article
Effects of Obesity and Feeding Avocado Extract on Gut Microbiota and Fecal Metabolomic Profile in Overweight/Obese Cats
by Roman Husnik, Jon Fletcher, Rachel Pilla, Donald Ingram, Frederic Gaschen, George Roth, Chih-Chun Chen and Jan Suchodolski
Microbiol. Res. 2025, 16(8), 190; https://doi.org/10.3390/microbiolres16080190 - 14 Aug 2025
Cited by 1 | Viewed by 4012
Abstract
Background/Objectives: Obesity is a growing problem in the feline population worldwide. An extract of unripe avocado (AvX) has been shown to attenuate gains in body weight and body fat in mice fed a high-fat diet. The aim of this study was to evaluate [...] Read more.
Background/Objectives: Obesity is a growing problem in the feline population worldwide. An extract of unripe avocado (AvX) has been shown to attenuate gains in body weight and body fat in mice fed a high-fat diet. The aim of this study was to evaluate the effects of overweight/obesity and AvX on gut microbiota (GM) and fecal metabolomics in cats with natural overweight/obesity. Methods: Ten naturally overweight/obese and ten lean purpose-bred domestic shorthair cats were included in this study. In a prospective, randomized, double-blind study, one group of overweight/obese cats received AvX, while the second group received maltodextrin for 16 weeks. Fecal samples were collected after spontaneous defecation at specific time points and submitted for analysis. Fecal samples of overweight/obese cats collected before administration of AvX/maltodextrin were also compared to fecal samples of lean cats. Results: There was a significant difference in the clustering of GM over time in the AvX group and between lean and overweight/obese cats. The abundance of Firmicutes in the group of cats receiving AvX decreased compared to baseline. AvX induced a trend toward an increased abundance of Dialister sp. and a trend of decreased abundances of SMB53, Roseburia sp., Blautia producta, Acidaminococcus sp., Akkermansia sp., Adlercreutzia sp., and Collinsella aerofaciens. The metabolites that significantly differed after AvX administration included tryptophan, indole-3-acetate, nicotinamine, and glycyl-proline. At the species level, abundances of Prevotella sp., Turicibacter sp., Clostridium sp., Veillonella sp., Dialister sp., Catenibacterium sp., Eubacterium biforme, Desulfovibrio sp., and Campylobacter sp. were significantly higher in lean cats. Abundances of Coriobacterium sp. and Ruminococcus gnavus were significantly higher in overweight/obese cats. Additionally, LEfSe analysis identified Dialister as the genus associated with AvX administration and Dialister, Prevotella, Ruminococcus, Campylobacter, Catenibacterium, Clostridium, Helicobacter, Eubacterium, Pseudoramibacter, Veillonella, S247, Turicibacter, and Phascolarctobacterium as bacteria associated with the lean state. Genus Coriobacterium and Enterococcus were associated with overweight/obesity. A correlation between the concentration of metabolites significantly different between the AvX/placebo groups and the abundances of detected bacterial taxa at the genus level was assessed and described. Conclusions: There are significant differences in the GM between lean and overweight/obese cats. AvX consumption appears to affect the composition of GM and fecal metabolite concentrations in naturally overweight/obese cats. Full article
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18 pages, 6242 KB  
Article
Analysis of Tribological Properties of Engine Lubricants Used in Hybrid Vehicles
by Daria Skonieczna, Oleksandr Vrublevskyi, Michał Janulin and Piotr Szczyglak
Materials 2024, 17(21), 5304; https://doi.org/10.3390/ma17215304 - 31 Oct 2024
Cited by 4 | Viewed by 1948
Abstract
A problem has been noted regarding the admixture of fuel to a low viscosity lubricant in hybrid electric vehicles (HEVs). This is very detrimental to the wear and tear of engine operating components. In this study, the operating conditions of HEVs were analysed. [...] Read more.
A problem has been noted regarding the admixture of fuel to a low viscosity lubricant in hybrid electric vehicles (HEVs). This is very detrimental to the wear and tear of engine operating components. In this study, the operating conditions of HEVs were analysed. Using X-ray fluorescence spectrometry (XRF), engine oils of two different viscosity classes were compared after the operating process and these data were compared with fresh reference samples. Attention was paid to the content of elements such as Ca, Zn, Mo, Sn, Cd, Fe Pb, Si, Cu, and Ni. The depletion of anti-wear additives, as well as the higher content of metallic wear products relative to the operated 5W30 (engine oil), contributed to the overall assessment of the lubricity of the 0W30 oil, as well as to the tribological results. Then, under laboratory conditions, oil samples contaminated with up to 1 to 8% fuel were subjected to rheological (mini AV-X viscometer) and tribological (four-ball tester) tests. The dependence of the local pressure at the metal-to-metal contact point in the kinematic node on viscosity showed the dissimilar nature of the used and fresh oil and the divergence of the domains for the two groups of samples. Increasing the fuel contamination of used oil above 4% drastically reduces the pressure responsible for maintaining the oil film. In order to improve lubricant performance during HEV operation in urban conditions, it was proposed to carry out extra-urban traffic driving in order to evaporate the fuel from the engine oil. A shorter oil change interval is also recommended. Full article
(This article belongs to the Section Mechanics of Materials)
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12 pages, 1724 KB  
Article
Histological Variations in Cucumber Grafted Plants and Their Effect on Yield
by Valentín Robledo-Torres, Areli González-Cortés, Laura Raquel Luna-García, Rosalinda Mendoza-Villarreal, Miguel Ángel Pérez-Rodríguez and Neymar Camposeco-Montejo
Agronomy 2024, 14(7), 1377; https://doi.org/10.3390/agronomy14071377 - 26 Jun 2024
Cited by 10 | Viewed by 2685
Abstract
Cucumber is a vegetable crop of economic importance in Mexico. In 2023, fresh or frozen cucumber and pickle international sales reached USD 783M, placing Mexico in second rank among countries with the highest currency inflow in the world. This crop is mostly grown [...] Read more.
Cucumber is a vegetable crop of economic importance in Mexico. In 2023, fresh or frozen cucumber and pickle international sales reached USD 783M, placing Mexico in second rank among countries with the highest currency inflow in the world. This crop is mostly grown under protected environments with new production technologies, including rootstocks that are tolerant to biotic and abiotic factors that limit the yield and quality of the harvest. Therefore, the goal of this work was to assess three cucurbits as rootstocks (Cucurbita maxima, Cucurbita moschata and Citrullus lanatus), as well as studying the response of cucumber crop to the tested rootstocks. The following treatments were assessed: T1:PSP = cucumber Cv. Paraizo F1 without rootstock; T2:P/MA = cucumber grafted over Cucurbita maxima; T3:P/MO = cucumber grafted over Cucurbita moschata; T4:P/CL = cucumber grafted over Citrullus lanatus Citroides Var. The assessed variables included the number of fruits per plant (NFPP), fruit weight per plant (PFPP), average fruit weight (PPF), plant dry weight (PSP), xylem vessel area (AVX), number of xylem vessels (NVX), vascular bundle area (AHV) and number of vascular bundles (NHV) in roots (R), basal stalk (TB) and apical stalk (AT). Significant differences among treatments were found in the results for variables: NFPP, highlighting that T2:P/MA was superior by 46.15% versus T1:PSP and by 67.69% versus T3:P/MO. Regarding PFPP, T2:P/MA achieved the highest weight (5445 g), as it proved superior by 99.45% than the cucumber without rootstock (T1:PSP). Regarding PSP, T2:P/MA achieved the highest weight (196.65 g), significantly exceeding T1 by 137.5%. Regarding AVXR, T4:P/CL had the highest value (30,063 µm2). Regarding NHVR, watermelon had (T4:P/CL) 39.33% more vascular bundles than the root system of cucumber (T1:PSP). Treatments T2:P/MA and T4:P/CL had the highest values at AVXTB, while for variable NVXTB, treatments T3:P/MO and T2:P/MA were almost equal, surpassing non-grafted cucumber by 175.47%. However, T2:P/MA showed the greatest AHVTB, and T1:PSP was significantly superior to T3:P/MO, by 34.93%, for NHVTB. Furthermore, positive and significant correlations were found among PFPP, AHVR, and AVXTB, as well as among PSP, AVXTB, and AHVTB. Therefore, we may say that having a larger area of vascular vessels in the roots and a larger area of xylem vessels in the basal stalk leads to higher fruit yields per plant. In the same vein, the use of rootstocks is a sustainable alternative to increase fruit yield. Full article
(This article belongs to the Section Horticultural and Floricultural Crops)
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21 pages, 1201 KB  
Article
Parallel Implementation of Lightweight Secure Hash Algorithm on CPU and GPU Environments
by Hojin Choi, SeongJun Choi and SeogChung Seo
Electronics 2024, 13(5), 896; https://doi.org/10.3390/electronics13050896 - 26 Feb 2024
Cited by 5 | Viewed by 5591
Abstract
Currently, cryptographic hash functions are widely used in various applications, including message authentication codes, cryptographic random generators, digital signatures, key derivation functions, and post-quantum algorithms. Notably, they play a vital role in establishing secure communication between servers and clients. Specifically, servers often need [...] Read more.
Currently, cryptographic hash functions are widely used in various applications, including message authentication codes, cryptographic random generators, digital signatures, key derivation functions, and post-quantum algorithms. Notably, they play a vital role in establishing secure communication between servers and clients. Specifically, servers often need to compute a large number of hash functions simultaneously to provide smooth services to connected clients. In this paper, we present highly optimized parallel implementations of Lightweight Secure Hash (LSH), a hash algorithm developed in Korea, on server sides. To optimize LSH performance, we leverage two parallel architectures: AVX-512 on high-end CPUs and NVIDIA GPUs. In essence, we introduce a word-level parallel processing design suitable for AVX-512 instruction sets and a data parallel processing design appropriate for the NVIDIA CUDA platform. In the former approach, we parallelize the core functions of LSH using AVX-512 registers and instructions. As a result, our first implementation achieves a performance improvement of up to 50.37% compared to the latest LSH AVX-2 implementation. In the latter approach, we optimize the core operation of LSH with CUDA PTX assembly and apply a coalesced memory access pattern. Furthermore, we determine the optimal number of blocks/threads configuration and CUDA streams for RTX 2080Ti and RTX 3090. Consequently, in the RTX 3090 architecture, our optimized CUDA implementation achieves about a 180.62% performance improvement compared with the initially ported LSH implementation to the CUDA platform. As far as we know, this is the first work on optimizing LSH with AVX-512 and NVIDIA GPU. The proposed implementation methodologies can be used alone or together in a server environment to achieve the maximum throughput of LSH computation. Full article
(This article belongs to the Special Issue Big Data and Cyber Security: Emerging Approaches and Applications)
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18 pages, 2575 KB  
Article
Improving Performance of Massive Text Real-Time Classification for Document Confidentiality Management
by Lingling Tan, Junkai Yi and Fei Yang
Appl. Sci. 2024, 14(4), 1565; https://doi.org/10.3390/app14041565 - 15 Feb 2024
Cited by 8 | Viewed by 2825
Abstract
For classified and sensitive electronic documents within the scope of enterprises and organizations, in order to standardize and strengthen the confidentiality management of enterprises and meet the actual needs of secret text classification, a document automatic classification optimization method based on keyword retrieval [...] Read more.
For classified and sensitive electronic documents within the scope of enterprises and organizations, in order to standardize and strengthen the confidentiality management of enterprises and meet the actual needs of secret text classification, a document automatic classification optimization method based on keyword retrieval and the kNN classification algorithm is proposed. The method supports keyword classification management, provides users with keywords of multiple risk levels, and then combines a matching scanning algorithm to label keywords of different levels. The text with labels is used as the training set of the kNN algorithm to classify the target text and realize the classification protection of text data. Aimed at solving the shortcomings of large feature vector dimension, low classification efficiency, and low accuracy in existing kNN text classification methods, an optimization method is proposed using a feature selection algorithm and a kNN algorithm based on an AVX instruction set to realize real-time classification of massive texts. By constructing a keyword dictionary and an optimized feature vector, parallel calculation of the feature vector weight and distance vector is realized, and the accuracy and efficiency of text classification are improved. The experimental results show that the multi-classification effect of the feature selection algorithm used in this paper, tf-DE, is better than that of the traditional tf-idf algorithm, and the classification effect of kNN is comparable to that of the support vector machine (SVM) algorithm. With the increase in feature vector dimensions, the classification effect of the text classification algorithm is improved and the classification time also increases linearly. The AVX-256 acceleration method takes about 55% of the time of the original version, thus verifying the effect of multi-classification of massive texts for document confidentiality management. Full article
(This article belongs to the Special Issue Cross-Applications of Natural Language Processing and Text Mining)
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15 pages, 2667 KB  
Article
Single-Instruction-Multiple-Data Instruction-Set-Based Heat Ranking Optimization for Massive Network Flow
by Lingling Tan, Yongyue Wang, Junkai Yi and Fei Yang
Electronics 2023, 12(24), 5026; https://doi.org/10.3390/electronics12245026 - 16 Dec 2023
Cited by 2 | Viewed by 1792
Abstract
In order to cope with the massive scale of traffic and reduce the memory overhead of traffic statistics, the traffic statistics method based on the Sketch algorithm has become a research hotspot for traffic statistics. This paper studies the problem of the top-k [...] Read more.
In order to cope with the massive scale of traffic and reduce the memory overhead of traffic statistics, the traffic statistics method based on the Sketch algorithm has become a research hotspot for traffic statistics. This paper studies the problem of the top-k flow statistics based on the Sketch algorithm and proposes a method to estimate the flow heat from massive network traffic using the Sketch algorithm and identify the kth flow with the highest heat by using a bitonic sort algorithm. In view of the performance difficulties of applying multiple hash functions in the implementation of the Sketch algorithm, the Single-Instruction-Multiple-Data (SIMD) instruction set is adopted to improve the performance of the Sketch algorithm so that SIMD instructions can process multiple fragments of data in a single step, implement multiple hash operations at the same time, compare and sort multiple flow tables at the same time. Thus, the throughput of the execution task is improved. Firstly, the elements of data flow are described and stored in the form of vectors, while the construction, analysis, and operation of data vectors are realized by SIMD instructions. Secondly, the multi-hash operation is simplified into a single vector operation, which reduces the CPU computing resource consumption of the Sketch algorithm. At the same time, the SIMD instruction set is used to optimize the parallel comparison operation of the flow table in a bitonic sort algorithm. Finally, the SIMD instruction set is used to optimize the functions in the Sketch algorithm and top-k sorting algorithm program, and the optimized code is tested and analyzed. The experimental results show that the time consumed by the advanced vector extensions (AVX)-instructions-optimized version has a significant reduction compared to the original version. When the length of KEY is 96 bytes, the instructions consumed by multiple hash functions account for less in the entire Sketch algorithm, and the time consumed by the optimized version of AVX is about 67.2% of that in the original version. As the length of KEY gradually increases to 256 bytes, the time consumed by the optimized version of AVX decreases to 53.8% of the original version. The simulation results show that the AVX optimization algorithm is effective in improving the measurement efficiency of network flow. Full article
(This article belongs to the Special Issue Recent Advances and Applications of Computational Intelligence)
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12 pages, 1542 KB  
Article
Effects of an Unripe Avocado Extract on Glycaemic Control in Individuals with Obesity: A Double-Blinded, Parallel, Randomised Clinical Trial
by Lijun Zhao, Donald K. Ingram, Eric Gumpricht, Trent De Paoli, Xiao Tong Teong, Bo Liu, Trevor A. Mori, Leonie K. Heilbronn and George S. Roth
Nutrients 2023, 15(22), 4812; https://doi.org/10.3390/nu15224812 - 17 Nov 2023
Cited by 5 | Viewed by 5266
Abstract
Background: Unripe avocados (Persea americana) are naturally enriched in mannoheptulose (MH), which is a candidate caloric restriction mimetic. Objectives: To evaluate the effects of a diet supplement made from unripe avocado on glucose tolerance, and cardiometabolic risk factors in free-living nondiabetic [...] Read more.
Background: Unripe avocados (Persea americana) are naturally enriched in mannoheptulose (MH), which is a candidate caloric restriction mimetic. Objectives: To evaluate the effects of a diet supplement made from unripe avocado on glucose tolerance, and cardiometabolic risk factors in free-living nondiabetic adults with obesity. Methods: In a double-blinded, randomised controlled trial, 60 adults (female n = 47, age 48 ± 13 years, BMI 34.0 ± 2.6 kg/m2) were stratified by sex and randomised to avocado extract (AvX, 10 g finely ground, freeze-dried unripe avocado) or placebo (10 g finely ground cornmeal plus 5% spinach powder) daily, for 12 weeks. The primary outcome was a change in glucose area under the curve (AUC) in response to a 75 g oral glucose tolerance test. A post-hoc analysis was subsequently performed in a subgroup with insulin AUC above the median of baseline values after removal of participants >2 SD from the mean. Results: There were no between-group differences in glucose AUC (p = 0.678), insulin AUC (p = 0.091), or cardiovascular outcomes. In the subgroup analysis, insulin AUC was lower in AxV versus placebo (p = 0.024). Conclusions: Daily consumption of unripe avocado extract enriched in MH did not alter glucose tolerance or insulin sensitivity in nondiabetic adults with obesity, but the data provided preliminary evidence for a benefit in insulin AUC in a subgroup of participants with elevated baseline postprandial insulin levels. Full article
(This article belongs to the Section Nutrition and Obesity)
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15 pages, 1452 KB  
Article
K-XMSS and K-SPHINCS+: Enhancing Security in Next-Generation Mobile Communication and Internet Systems with Hash Based Signatures Using Korean Cryptography Algorithms
by Minjoo Sim, Siwoo Eum, Gyeongju Song, Yujin Yang, Wonwoong Kim and Hwajeong Seo
Sensors 2023, 23(17), 7558; https://doi.org/10.3390/s23177558 - 31 Aug 2023
Cited by 7 | Viewed by 3768
Abstract
As Mobile Communication and Internet Systems (MCIS) have rapidly developed, security issues related to MCIS have become increasingly important. Therefore, the development and research of security technologies for mobile communication and internet systems are actively being conducted. Hash-Based Signature (HBS) uses a hash [...] Read more.
As Mobile Communication and Internet Systems (MCIS) have rapidly developed, security issues related to MCIS have become increasingly important. Therefore, the development and research of security technologies for mobile communication and internet systems are actively being conducted. Hash-Based Signature (HBS) uses a hash function to construct a digital signature scheme, where its security is guaranteed by the collision resistance of the hash function used. To provide sufficient security in the post-quantum environment, the length of hash should be satisfied for the security requirement. Modern HBS can be classified into stateful and stateless schemes. Two representative stateful and stateless HBS are eXtended Merkle Signature Scheme(XMSS) and SPHINCS+, respectively. In this paper, we propose two HBS schemes: K-XMSS and K-SPHINCS+, which replace internal hash functions of XMSS and SPHINCS+ with Korean cryptography algorithms. K-XMSS is a stateful signature, while K-SPHINCS+ is its stateless counterpart. We showcase the reference implementation of K-XMSS and K-SPHINCS+ employing Lightweight Secure Hash (LSH) and two hash functions based on block ciphers (i.e., CHAM and LEA) as the internal hash function. In addition, K-XMSS and K-SPHINCS+ using Advanced Vector Extensions 2 (AVX2) have been provided, demonstrating that they can be optimized for better performance using advanced implementation techniques than previous approaches. Full article
(This article belongs to the Collection Cryptography and Security in IoT and Sensor Networks)
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10 pages, 257 KB  
Article
Acceleration of Particle Swarm Optimization with AVX Instructions
by Jakub Safarik and Vaclav Snasel
Appl. Sci. 2023, 13(2), 734; https://doi.org/10.3390/app13020734 - 4 Jan 2023
Cited by 2 | Viewed by 3026
Abstract
Parallel implementations of algorithms are usually compared with single-core CPU performance. The advantage of multicore vector processors decreases the performance gap between GPU and CPU computation, as shown in many recent pieces of research. With the AVX-512 instruction set, there will be another [...] Read more.
Parallel implementations of algorithms are usually compared with single-core CPU performance. The advantage of multicore vector processors decreases the performance gap between GPU and CPU computation, as shown in many recent pieces of research. With the AVX-512 instruction set, there will be another performance boost for CPU computations. The availability of parallel code running on CPUs made them much easier and more accessible than GPUs. This article compares the performances of parallel implementations of the particle swarm optimization algorithm. The code was written in C++, and we used various techniques to obtain parallel execution through Advanced Vector Extensions. We present the performance on various benchmark functions and different problem configurations. The article describes and compares the performance boost gained from parallel execution on CPU, along with advantages and disadvantages of parallelization techniques. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
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9 pages, 705 KB  
Article
Energy Efficiency of a New Parallel PIC Code for Numerical Simulation of Plasma Dynamics in Open Trap
by Igor Chernykh, Igor Kulikov, Vitaly Vshivkov, Ekaterina Genrikh, Dmitry Weins, Galina Dudnikova, Ivan Chernoshtanov and Marina Boronina
Mathematics 2022, 10(19), 3684; https://doi.org/10.3390/math10193684 - 8 Oct 2022
Cited by 6 | Viewed by 2356
Abstract
The generation of energy-efficient parallel scientific codes became very important in the time of carbon footprint reduction. In this paper, we briefly present our latest particle-in-cell code with the results of a numerical simulation of plasma dynamics in an open trap. This code [...] Read more.
The generation of energy-efficient parallel scientific codes became very important in the time of carbon footprint reduction. In this paper, we briefly present our latest particle-in-cell code with the results of a numerical simulation of plasma dynamics in an open trap. This code can be auto-vectorized by the Fortran compiler for Intel Xeon processors with AVX-512 instructions such as Intel Xeon Phi and the highest series of all generations of Intel Xeon Scalable processors. Efficient use of processor architecture is the main feature of an energy-efficient solution. We present a step-by-step methodology of energy consumption calculation using Intel hardware features and Intel VTune software. We also give an estimated value of carbon footprint with the impact of high-performance water cooled hardware. The Power Usage Effectiveness (PUE) in the case of high-performance water cooled hardware is equal to 1.03–1.05, and is up to 1.3 in the case of air-cooled systems. This means that power consumption of liquid cooled systems is lower than that air-cooled ones by up to 25%. All these factors play an important role in the carbon footprint reduction problem. Full article
(This article belongs to the Special Issue Parallel Computing and Applications)
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12 pages, 1097 KB  
Article
OMPEGAS: Optimized Relativistic Code for Multicore Architecture
by Elena N. Akimova, Vladimir E. Misilov, Igor M. Kulikov and Igor G. Chernykh
Mathematics 2022, 10(14), 2546; https://doi.org/10.3390/math10142546 - 21 Jul 2022
Cited by 2 | Viewed by 2433
Abstract
The paper presents a new hydrodynamical code, OMPEGAS, for the 3D simulation of astrophysical flows on shared memory architectures. It provides a numerical method for solving the three-dimensional equations of the gravitational hydrodynamics based on Godunov’s method for solving the Riemann problem and [...] Read more.
The paper presents a new hydrodynamical code, OMPEGAS, for the 3D simulation of astrophysical flows on shared memory architectures. It provides a numerical method for solving the three-dimensional equations of the gravitational hydrodynamics based on Godunov’s method for solving the Riemann problem and the piecewise parabolic approximation with a local stencil. It obtains a high order of accuracy and low dissipation of the solution. The code is implemented for multicore processors with vector instructions using the OpenMP technology, Intel SDLT library, and compiler auto-vectorization tools. The model problem of simulating a star explosion was used to study the developed code. The experiments show that the presented code reproduces the behavior of the explosion correctly. Experiments for the model problem with a grid size of 128×128×128 were performed on an 16-core Intel Core i9-12900K CPU to study the efficiency and performance of the developed code. By using the autovectorization, we achieved a 3.3-fold increase in speed in comparison with the non-vectorized program on the processor with AVX2 support. By using multithreading with OpenMP, we achieved an increase in speed of 2.6 times on a 16-core processor in comparison with the vectorized single-threaded program. The total increase in speed was up to ninefold. Full article
(This article belongs to the Special Issue Parallel Computing and Applications)
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16 pages, 3821 KB  
Article
An Avocado Extract Enriched in Mannoheptulose Prevents the Negative Effects of a High-Fat Diet in Mice
by Paul J. Pistell, Tadanobu Utsuki, Joseph Francis, Philip J. Ebenezer, Jennifer Terrebonne, George S. Roth and Donald K. Ingram
Nutrients 2022, 14(1), 155; https://doi.org/10.3390/nu14010155 - 29 Dec 2021
Cited by 9 | Viewed by 4252
Abstract
Beginning at 16 weeks of age and continuing for 44 weeks, male C57BL/6J were fed either a control (CON) diet; a high-fat (HF) diet (60% unsaturated); or the HF diet containing an extract of unripe avocados (AvX) enriched in the 7-carbon sugar mannoheptulose [...] Read more.
Beginning at 16 weeks of age and continuing for 44 weeks, male C57BL/6J were fed either a control (CON) diet; a high-fat (HF) diet (60% unsaturated); or the HF diet containing an extract of unripe avocados (AvX) enriched in the 7-carbon sugar mannoheptulose (MH), designed to act as a glycolytic inhibitor (HF + MH). Compared to the CON diet, mice on the HF diet exhibited higher body weights; body fat; blood lipids; and leptin with reduced adiponectin levels, insulin sensitivity, VO2max, and falls from a rotarod. Mice on the HF + MH diet were completely protected against these changes in the absence of significant diet effects on food intake. Compared to the CON diet, oxidative stress was also increased by the HF diet indicated by higher levels of total reactive oxygen species, superoxide, and peroxynitrite measured in liver samples by electron paramagnetic resonance spectroscopy, whereas the HF + MH diet attenuated these changes. Compared to the CON, the HF diet increased signaling in the mechanistic target of the rapamycin (mTOR) pathway, and the addition of the MH-enriched AvX to this diet attenuated these changes. Beyond generating further interest in the health benefits of avocados, these results draw further new attention to the effects of this rare sugar, MH, as a botanical intervention for preventing obesity. Full article
(This article belongs to the Section Nutrition and Obesity)
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16 pages, 5461 KB  
Article
Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
by Nur Mahammad, Felicity J. Ashcroft, Astrid J. Feuerherm, Samah Elsaadi, Esten N. Vandsemb, Magne Børset and Berit Johansen
Molecules 2021, 26(24), 7447; https://doi.org/10.3390/molecules26247447 - 9 Dec 2021
Cited by 5 | Viewed by 4583
Abstract
Cytosolic phospholipase A2α (cPLA2α) is the rate-limiting enzyme in releasing arachidonic acid and biosynthesis of its derivative eicosanoids. Thus, the catalytic activity of cPLA2α plays an important role in cellular metabolism in healthy as well as cancer cells. There is mounting evidence suggesting [...] Read more.
Cytosolic phospholipase A2α (cPLA2α) is the rate-limiting enzyme in releasing arachidonic acid and biosynthesis of its derivative eicosanoids. Thus, the catalytic activity of cPLA2α plays an important role in cellular metabolism in healthy as well as cancer cells. There is mounting evidence suggesting that cPLA2α is an interesting target for cancer treatment; however, it is unclear which cancers are most relevant for further investigation. Here we report the relative expression of cPLA2α in a variety of cancers and cancer cell lines using publicly available datasets. The profiling of a panel of cancer cell lines representing different tissue origins suggests that hematological malignancies are particularly sensitive to the growth inhibitory effect of cPLA2α inhibition. Several hematological cancers and cancer cell lines overexpressed cPLA2α, including multiple myeloma. Multiple myeloma is an incurable hematological cancer of plasma cells in the bone marrow with an emerging requirement of therapeutic approaches. We show here that two cPLA2α inhibitors AVX420 and AVX002, significantly and dose-dependently reduced the viability of multiple myeloma cells and induced apoptosis in vitro. Our findings implicate cPLA2α activity in the survival of multiple myeloma cells and support further studies into cPLA2α as a potential target for treating hematological cancers, including multiple myeloma. Full article
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