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Search Results (1,721)

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17 pages, 504 KB  
Article
Challenge and Opportunity? Arab Teachers’ Perspectives on Teacher Training in a Hebrew-Speaking Program
by Anat Reuter and Dolly Eliyahu-Levi
Educ. Sci. 2026, 16(2), 178; https://doi.org/10.3390/educsci16020178 - 23 Jan 2026
Abstract
The academic encounter between Jews and Arabs in Israel carries tensions stemming from a prolonged historical conflict, yet at the same time offers opportunities for authentic engagement that deepens mutual understanding between the groups. This study is grounded in contact theory and multiculturalism, [...] Read more.
The academic encounter between Jews and Arabs in Israel carries tensions stemming from a prolonged historical conflict, yet at the same time offers opportunities for authentic engagement that deepens mutual understanding between the groups. This study is grounded in contact theory and multiculturalism, focusing on the integration process of Arab women teachers in a Hebrew-speaking track at an academic college of education. The research explores the participants’ experiences against the backdrop of national tensions, asking how they perceive their teacher education journey in the Hebrew-speaking track in terms of challenges and benefits. The study is based on a qualitative–phenomenological approach, collecting data through interviews with 12 graduates who shared their experiences and reflections. The analysis reveals the participants’ explicit and implicit attitudes, the barriers they faced, and the gains they reported during their studies. Full article
(This article belongs to the Special Issue Teacher Preparation in Multicultural Contexts)
15 pages, 315 KB  
Article
Investigation of Feeding Problems and Their Associated Factors in Children with Developmental Disabilities in Saudi Arabia
by Walaa Abdullah Mumena, Sara Zaher, Maha Althowebi, Manar Alharbi, Reuof Alharbi, Maram Aloufi, Najlaa Alqurashi, Rana Qadhi, Sawsan Faqeeh, Arwa Alnezari, Ghadi A. Aljohani and Hebah Alawi Kutbi
Nutrients 2026, 18(2), 356; https://doi.org/10.3390/nu18020356 - 22 Jan 2026
Abstract
Background/Objectives: Children with developmental disabilities (DD) may experience feeding problems that increase their risk of malnourishment. However, data concerning factors linked to feeding problems in children with DD are lacking. The present study aimed to investigate feeding problems and their associated factors in [...] Read more.
Background/Objectives: Children with developmental disabilities (DD) may experience feeding problems that increase their risk of malnourishment. However, data concerning factors linked to feeding problems in children with DD are lacking. The present study aimed to investigate feeding problems and their associated factors in children with DD who are fed orally. This cross-sectional study included data from 160 children with DD aged 2–18 years, recruited from 9 disability centers and schools located in Madinah, Saudi Arabia. Methods: A total of 666 envelopes were distributed randomly to children to take home. Caregivers were asked to provide sociodemographic, health, and nutrition information. Feeding problems were assessed using a validated screening tool for eating/feeding problems (STEP-AR), which included 17 items divided into 5 subdomains (Aspiration risk, Food refusal, Food selectivity, Nutrition behaviors, and Skill). Phone interviews were conducted with caregivers within two weeks of data collection for dietary assessment. Results: The most frequently reported feeding problems involved feeding skills and food selectivity, with 39.3% unable to feed themselves, 33.1% showing overeating behavior, and 31.2% exhibiting pica-like behavior. Chewing difficulties (28.7%), limited food intake (25.6%), and swallowing challenges (21.2%) were moderately reported, while aspiration-related problems were less common. Multiple linear regression analysis revealed significant positive associations between feeding problems and caregiver education level, family income, caregiver’s relationship to the child, and the child’s living arrangement. Dietary intake was not associated with feeding problems. Conclusions: The findings of this study indicate a range of feeding problems and key sociodemographic factors associated with feeding problems in children with DD. These results highlight the need for targeted interventions such as behavioral support and caregiver education to effectively address and manage feeding challenges in children. Full article
(This article belongs to the Special Issue Clinical Nutrition in Newborns and Children with Disabilities)
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21 pages, 23996 KB  
Article
The Relationship Between Representational Culture of Decorative Walls in Subway Stations and Commuters’ Spatial Perception: A Case Study of Ping’anli Station in Beijing
by Zhifen Cheng and Yuliang Guo
Appl. Sci. 2026, 16(2), 1107; https://doi.org/10.3390/app16021107 - 21 Jan 2026
Abstract
Previous research on subway stations has emphasized indexicality, functionality, comfort, aesthetics, etc., while cultural representation has been neglected. Notably, however, cultural representations in subway stations shape the city image and affects residents’ sense of identity and belonging. In particular, cultural representations on the [...] Read more.
Previous research on subway stations has emphasized indexicality, functionality, comfort, aesthetics, etc., while cultural representation has been neglected. Notably, however, cultural representations in subway stations shape the city image and affects residents’ sense of identity and belonging. In particular, cultural representations on the decorative walls of subway stations play a crucial role. Therefore, the following questions can be asked: Do passengers perceive the representational culture in these subway stations? What is the relationship between the cultural representations on the decorative walls in subway stations and commuters’ spatial perception? Using a case study of the Ping’anli station in Beijing, in response to the research conducted by Xu Y.J. and other scholars, and adopting the method of data triangulation performed through content analysis, social media, and questionnaires, this paper analyses whether and how cultural representations on the decorative walls of subway stations affect commuters’ spatial perceptions. This study provides new insights into the influence of cultural representations in subway stations on commuters’ spatial perceptions. The findings reveal that cultural representations on decorative walls in subway stations do not fully align with commuters’ spatial perception. These findings can offer references for urban planning as well as the planning and design of decorative walls in subway stations. Full article
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22 pages, 1347 KB  
Article
Multi-Source Data Fusion for Anime Pilgrimage Recommendation: Integrating Accessibility, Seasonality, and Popularity
by Yusong Zhou and Yuanyuan Wang
Electronics 2026, 15(2), 419; https://doi.org/10.3390/electronics15020419 - 18 Jan 2026
Viewed by 85
Abstract
Anime pilgrimage refers to the act of fans visiting real-world locations featured in anime works, offering visual familiarity alongside cultural depth. However, existing studies on anime tourism provide limited computational support for selecting pilgrimage sites based on contextual and experiential factors. This study [...] Read more.
Anime pilgrimage refers to the act of fans visiting real-world locations featured in anime works, offering visual familiarity alongside cultural depth. However, existing studies on anime tourism provide limited computational support for selecting pilgrimage sites based on contextual and experiential factors. This study proposes an intelligent recommendation framework based on multi-source data fusion that integrates three key elements: transportation accessibility, seasonal alignment between the current environment and the anime’s depicted scene, and a Cross-Platform Popularity Index (CPPI) derived from major global platforms. We evaluate each pilgrimage location using route-based accessibility analysis, season-scene discrepancy scoring, and robustly normalized popularity metrics. These factors are combined into a weighted Multi-Criteria Decision Making (MCDM) model to generate context-aware recommendations. To rigorously validate the proposed approach, a user study was conducted using a ranking task involving popular destinations in Tokyo. Participants were presented with travel conditions, spatial relationships, and popularity scores and then asked to rank their preferences. We used standard ranking-based metrics to compare system-generated rankings with participant choices. Furthermore, we conducted an ablation study to quantify the individual contribution of accessibility, seasonality, and popularity. The results demonstrate strong alignment between the model and user preferences, confirming that incorporating these three dimensions significantly enhances the reliability and satisfaction of real-world anime pilgrimage planning. Full article
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15 pages, 246 KB  
Article
Laying the Foundation for an Elementary School Sleep Education Program
by Alzena Ilie, Peyton Williams, Gabrielle Rigney, Shelly K. Weiss, Sarah Bluden and Penny V. Corkum
Children 2026, 13(1), 138; https://doi.org/10.3390/children13010138 - 18 Jan 2026
Viewed by 84
Abstract
Background/Objectives: Many elementary school-aged children (i.e., 5 to 12 years old) experience sleep difficulties that negatively impact their daytime functioning. Despite this high prevalence, sleep education is rarely included in school curricula and evidence-based interventions are limited. To better understand this gap, a [...] Read more.
Background/Objectives: Many elementary school-aged children (i.e., 5 to 12 years old) experience sleep difficulties that negatively impact their daytime functioning. Despite this high prevalence, sleep education is rarely included in school curricula and evidence-based interventions are limited. To better understand this gap, a needs assessment was conducted to inform the development of a sleep education program. Method: Semi-structured virtual interviews were conducted with 14 elementary school teachers in Nova Scotia, Canada. Participants were asked 20 questions about their students’ sleep and its impact, teachers’ needs and practices in sleep education, what a sleep education program would look like, and how it could be delivered. During the interview, participants watched the online ABCs of SLEEPING storybook as a potential foundation for developing a sleep education program, and interview themes were analyzed using deductive thematic analysis. Results: All teachers identified poor sleep as an issue impacting students’ behavior and learning, and reported that they had a lack of resources to teach sleep education. Teachers believed the storybook could be used with their students and integrated into the curriculum. Recommended modifications include making the storybook available for families, adding interactive activities and student discussions, providing teacher resources, and tailoring the content to be suitable for both lower and upper elementary school-aged students. Most teachers indicated that the storybook could be adapted for upper elementary students with more age-appropriate vocabulary and visuals. Conclusions: The findings from this needs assessment will inform the development of an elementary school sleep education program using the ABCs of SLEEPING storybook as the foundation of the program, while noting limitations such as sample diversity. Full article
(This article belongs to the Special Issue Children’s Well-Being and Mental Health in an Educational Context)
24 pages, 792 KB  
Article
The Mediating Role of Motivational Self-Regulation in the Relationship Between Perceived Support from Family and Teachers and Academic Achievement
by Zeltia Martínez-López, José Eulogio Real Deus, Mª Emma Mayo, Natalia Silva and Carolina Tinajero
Educ. Sci. 2026, 16(1), 138; https://doi.org/10.3390/educsci16010138 - 16 Jan 2026
Viewed by 226
Abstract
Perceived social support is considered essential for enhancing the inner academic motivational resources of students, in particular motivational self-regulation. We aimed to examine the possible associative mediation of motivational regulation strategies in the relationship between perceived support from family and teachers and academic [...] Read more.
Perceived social support is considered essential for enhancing the inner academic motivational resources of students, in particular motivational self-regulation. We aimed to examine the possible associative mediation of motivational regulation strategies in the relationship between perceived support from family and teachers and academic achievement. A convenience sample of secondary education students was recruited. The students were asked to complete self-report questionnaires on perceived social support and motivational self-regulation strategies, and their academic grades were also recorded. Mediation regression analysis was used to test the mediation model proposed in the study. Three motivational regulation strategies mediated the relationship between perceived support and academic achievement: work-avoidance self-talk, self-efficacy enhancement, and enhancement of situational interest. Different support provisions were found to have cumulative positive and negative associations with the strategies. The findings suggest that perceived social support is associated with more autonomous forms of motivational regulation and lower levels of work-avoidance among students. Full article
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19 pages, 2514 KB  
Article
Making It Work: The Invisible Work of Mothers in Pursuit of Inclusion in School Settings
by Jessica A. Harasym, Paige Reeves and Shanon K. Phelan
Soc. Sci. 2026, 15(1), 43; https://doi.org/10.3390/socsci15010043 - 14 Jan 2026
Viewed by 241
Abstract
Inclusive education is at the forefront of transnational policy agendas. Yet, normative, deficit-oriented disability discourses and institutional gaps continue to shape how inclusion is enacted in schools, often displacing extensive and unacknowledged labour onto families, especially mothers. Drawing on feminist theories of invisible [...] Read more.
Inclusive education is at the forefront of transnational policy agendas. Yet, normative, deficit-oriented disability discourses and institutional gaps continue to shape how inclusion is enacted in schools, often displacing extensive and unacknowledged labour onto families, especially mothers. Drawing on feminist theories of invisible work, this article critically examines the everyday labour performed by mothers of disabled children as they navigate inclusive education systems in Alberta, Canada. Situated within a broader collective case study, this analysis asks: What forms of invisible work do mothers undertake in pursuit of inclusion within education systems labelled as inclusive? Semi-structured interviews were conducted with nine mothers of disabled children. Reflexive thematic analysis illuminated four intersecting dimensions of invisible work: (1) working within the system, (2) working to fit the system, (3) crafting system workarounds, and (4) working above and beyond the system. These forms of work reveal how inclusive education systems rely on mothers to bridge the gap between policy rhetoric and lived experiences. Findings illuminate how mothers’ invisible work simultaneously sustains, negotiates, and resists systemic ableism, highlighting the need to recognize and redistribute this work and reimagine inclusion as a shared structural responsibility rather than an individual, maternal pursuit. Full article
(This article belongs to the Special Issue Towards Equity: Services for Disabled Children and Youth)
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17 pages, 1244 KB  
Article
The Research on the Handwriting Stability in Different Devices and Conditions
by Hsiang-Ju Lai, Long-Huang Tsai, Kung-Yang Hsu and Wen-Chao Yang
Sensors 2026, 26(2), 538; https://doi.org/10.3390/s26020538 - 13 Jan 2026
Viewed by 208
Abstract
With the rapid advancement of technology in recent years, signatures on contracts and documents have increasingly shifted from traditional handwritten forms on paper to digital handwritten signatures executed on devices (hereafter referred to as digital tablets). This transition introduces new challenges for forensic [...] Read more.
With the rapid advancement of technology in recent years, signatures on contracts and documents have increasingly shifted from traditional handwritten forms on paper to digital handwritten signatures executed on devices (hereafter referred to as digital tablets). This transition introduces new challenges for forensic document examination due to the differences in writing instruments. According to the European Network of Forensic Science Institutes (ENFSI), a Digital Capture Signature (DCS) refers to data points captured during the writing process on digital devices such as tablets, smartphones, or signature pads. In addition to retaining the visual image of the signature, DCS provides more information previously unavailable, including pen pressure, stroke order, and writing speed. These features possess potential forensic value and warrant further study and evaluation. This study employs three devices—Samsung Galaxy Tab S10, Apple iPad Pro, and Apple iPad Mini—together with their respective styluses as experimental tools. Using custom-developed handwriting capture software for both Android and iOS platforms, we simulated signature-writing scenarios common in the financial and insurance industries. Thirty participants were asked to provide samples of horizontal Chinese, English, and number writings (FUJ-IRB NO: C113187), which were subsequently normalized and segmented into characters. For analysis, we adopted distance-based time-series alignment algorithms (FastDTW and SC-DTW) to match writing data across different instances (intra- and inter-writer). The accumulated distances between corresponding data points, such as coordinates and pressure, were used to assess handwriting stability and to study the differences between same-writer and different-writer samples. The findings indicate that preprocessing through character centroid alignment, followed by the analysis, substantially reduces the average accumulated distance of handwriting. This procedure quantifies the stability of an individual’s handwriting and enables differentiation between same-writer and different-writer scenarios based on the distribution of DCS distances. Furthermore, the use of styluses provides more precise distinctions between same- and different-writer samples compared with direct finger-based writing. In the context of rapid advancements in artificial intelligence and emerging technologies, this preliminary study aims to contribute foundational insights into the forensic application of digital signature examination. Full article
(This article belongs to the Special Issue Digital Image Processing and Sensing Technologies—Second Edition)
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23 pages, 11150 KB  
Article
Preference Evaluation of Reverberation Times for Traditional Inner Mongolian Musical Instruments in Performance Spaces
by Xiaoyun Yue, Shuonan Ni, Zhongzheng Qu, Zifan Xu, Da Yang and Xiangdong Zhu
Buildings 2026, 16(2), 331; https://doi.org/10.3390/buildings16020331 - 13 Jan 2026
Viewed by 110
Abstract
As unique forms of intangible cultural heritage of Inner Mongolia, traditional musical instruments from the region have undergone significant changes alongside socioeconomic development and evolving performance styles. The performance environment has transitioned from early outdoor and non-fixed venues to professional concert halls. Existing [...] Read more.
As unique forms of intangible cultural heritage of Inner Mongolia, traditional musical instruments from the region have undergone significant changes alongside socioeconomic development and evolving performance styles. The performance environment has transitioned from early outdoor and non-fixed venues to professional concert halls. Existing research has demonstrated a correlation between the acoustic quality of performance halls and their objective architectural acoustic parameters. However, no studies have been conducted in China on the acoustic parameters suitable for the performance environments of traditional Inner Mongolian musical instruments. This study determined the optimal acoustic environment for performances of traditional musical instruments, unique to Inner Mongolia, by employing computer simulations and subjective listening experiments in representative performance spaces. Participants were asked to select preferred audio samples of different reverberation times, generated by convolving the impulse responses of simulated spatial models with dry recordings of the instruments. Statistical analysis of the results revealed that the optimal reverberation times for traditional Inner Mongolian instruments are 1.2 s and 1.4 s in a theater space, and 0.9 s and 1.1 s in a rectangular space. Furthermore, under the influence of different factors, the four instruments exhibited distinct preferences for optimal reverberation values in the sampled spaces. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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15 pages, 251 KB  
Article
Ethical Decision-Making and Clinical Ethics Support in Italian Neonatal Intensive Care Units: Results from a National Survey
by Clara Todini, Barbara Corsano, Simona Giardina, Simone S. Masilla, Costanza Raimondi, Pietro Refolo, Dario Sacchini and Antonio G. Spagnolo
Healthcare 2026, 14(2), 181; https://doi.org/10.3390/healthcare14020181 - 11 Jan 2026
Viewed by 248
Abstract
Background/Objectives: Neonatal Intensive Care Units (NICUs) constitute a highly complex clinical environment characterized by patient fragility and frequent ethically sensitive decisions. To date, systematic studies investigating how Italian NICUs address these challenges and what forms of ethics support are effectively available are lacking. [...] Read more.
Background/Objectives: Neonatal Intensive Care Units (NICUs) constitute a highly complex clinical environment characterized by patient fragility and frequent ethically sensitive decisions. To date, systematic studies investigating how Italian NICUs address these challenges and what forms of ethics support are effectively available are lacking. The aim of this study is therefore to assess how ethical issues are managed in Italian NICUs, with particular attention to the availability, use, and perceived usefulness of clinical ethics support in everyday practice. Methods: A 25-item questionnaire was developed by adapting an existing tool for investigating clinical ethics activities to the neonatal context. Following expert review by the GIBCE (Gruppo Interdisciplinare di Bioetica Clinica e Consulenza Etica in ambito sanitario), the final instrument covered four areas (general data, experience with ethical dilemmas, tools and procedures, opinions and training needs). A manual web search identified all Italian NICUs and their clinical directors, who were asked to disseminate the survey among staff. Participation was voluntary and anonymous. Data collection was conducted via Google Forms and analyzed through qualitative thematic analysis. Results: A total of 217 questionnaires were collected. The most frequent ethical dilemmas concern quality of life with anticipated multiple or severe disabilities (72.4%) and decisions to withdraw or withhold life-sustaining treatments (64.5%). Major challenges include fear of medico-legal repercussions (57.6%) and communication divergences between physicians and nurses (49.8%). More than half of respondents (52.1%) reported no formal training in clinical ethics, and 68.7% had never developed a Shared Care Plan (Shared Document for healthcare ethics planning) as defined by the Italian Law 219/2017. Conclusions: Findings highlight marked fragmentation in ethical practices across Italian NICUs. On this basis, establishing structured and accessible CEC services could help promote consistency, reinforce shared ethical standards, and support transparent and equitable decision-making in critical neonatal care. Full article
23 pages, 895 KB  
Article
Genealogy and Law Without Borders: Comparative Nationality Regimes and the Global Circulation of Descent
by Oluwaseyi B. Ayeni, Oluwajuwon M. Omigbodun and Oluwakemi T. Onibalusi
Genealogy 2026, 10(1), 11; https://doi.org/10.3390/genealogy10010011 - 6 Jan 2026
Viewed by 235
Abstract
Citizenship is not only a legal status but also a form of recognition. Every state defines who belongs by tracing lines of descent, yet the way ancestry is proven differs widely. This study compares nationality laws in Europe, Africa, and North America to [...] Read more.
Citizenship is not only a legal status but also a form of recognition. Every state defines who belongs by tracing lines of descent, yet the way ancestry is proven differs widely. This study compares nationality laws in Europe, Africa, and North America to show how evidence shapes access to citizenship. It asks what kinds of proof states require and what happens when those forms of proof are missing. The analysis draws on nationality laws, constitutional texts, case decisions, and administrative practice. The findings show that Europe relies on documents and registration systems that treat records as truth, while African states face gaps in documentation that leave many citizens unrecognised. In North America, technology and DNA testing have made biology a new measure of belonging. Across these regions, the law of descent has become a law of evidence. Documents and DNA dominate, while oral and community genealogy have lost authority. These evidentiary habits travel across borders, shaping how migrants and diasporas prove identity in a world that equates paperwork with legitimacy. The study concludes that certainty and fairness can exist together if states accept multiple paths to proof. When documents, sworn statements, and community testimony are combined, the law can recognise descent without excluding those who lack official records. Belonging should rest not only on what is written or tested but also on what is known and trusted. Full article
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15 pages, 287 KB  
Article
Identities of Female Entrepreneurs from Different Periods
by Lučka Klanšek and Boštjan Antončič
Adm. Sci. 2026, 16(1), 24; https://doi.org/10.3390/admsci16010024 - 4 Jan 2026
Viewed by 318
Abstract
This article explores how female entrepreneurs construct and negotiate entrepreneurial identities across socialist, transition, and post-socialist periods in Slovenia. Drawing on feminist, post-structuralist, and identity-theory perspectives, we ask what determines women’s entrepreneurial identities and how multiple roles and changing institutions shape them. Using [...] Read more.
This article explores how female entrepreneurs construct and negotiate entrepreneurial identities across socialist, transition, and post-socialist periods in Slovenia. Drawing on feminist, post-structuralist, and identity-theory perspectives, we ask what determines women’s entrepreneurial identities and how multiple roles and changing institutions shape them. Using a qualitative multiple-case design, we analyze 15 information-rich cases selected through purposive sampling and based on in-depth semi-structured interviews and supporting documents. Qualitative content analysis and cross-case comparison identified patterns within and across the three periods. Results show that women’s motives combine economic, autonomy, and mission-driven goals; that entrepreneurial identity is closely intertwined with motherhood, partnership, and community roles; and that evolving ecosystems offer increasing but still fragmented support. Identity work intensifies at transitions between employment and entrepreneurship and when growth ambitions confront care responsibilities. We conclude that female entrepreneurial identities in Slovenia are historically and institutionally embedded and that gender-integrative, context-sensitive ecosystem measures are needed to support diverse entrepreneurial pathways and long-term, socially responsible growth. Full article
13 pages, 779 KB  
Article
Culture Growth Phase-Dependent Influence of Extracellular Vesicles Derived from Stem Cells from Human Exfoliated Deciduous Teeth on Oral Mucosa Cells Proliferation in Paracrine Co-Culture with Urethral Epithelium: Implication for Urethral Reconstruction
by Tsuyoshi Kawaharada, Daisuke Watanabe, Kazuki Yanagida, Kashia Goto, Ailing Hu, Yuhei Segawa, Madoka Higuchi, Masayuki Shinchi, Akio Horiguchi, Tatsuya Takagi and Akio Mizushima
Int. J. Mol. Sci. 2026, 27(1), 314; https://doi.org/10.3390/ijms27010314 - 27 Dec 2025
Viewed by 336
Abstract
Urethral stricture is a disease of fibrotic narrowing that compromises the urethral mucosa and spongiosum. Oral mucosal graft urethroplasty delivers excellent outcomes in complex cases, yet its procedural demands restrict availability beyond specialized centers. Endoscopic transplantation of oral mucosa has been proposed; while [...] Read more.
Urethral stricture is a disease of fibrotic narrowing that compromises the urethral mucosa and spongiosum. Oral mucosal graft urethroplasty delivers excellent outcomes in complex cases, yet its procedural demands restrict availability beyond specialized centers. Endoscopic transplantation of oral mucosa has been proposed; while feasibility is shown, clinical efficacy remains suboptimal. We asked whether extracellular vesicles from stem cells of human exfoliated deciduous teeth (SHED-EVs) promote oral mucosa fibroblast (OMF) growth under urethra-mimetic paracrine conditions and whether culture growth phase tunes EV function. SHED-EVs were collected during logarithmic (SHED-EV-L) or stationary (SHED-EV-S) phases under xeno-free conditions, isolated by a standardized workflow, and characterized by nanoparticle tracking analysis. miRNA cargo was profiled with a human miRNA microarray platform and normalized for comparative analyses. OMF proliferation was quantified in a horizontal indirect co-culture with urethral epithelial cells using incubator-based time-lapse imaging. SHED-EV-L produced a sustained pro-proliferative effect across 24–96 h, whereas SHED-EV-S showed a weaker early effect with a late catch-up; both exceeded vehicle at 96 h. Fibrosis-related miRNA heat maps showed culture growth phase-dependent patterns: SHED-EV-L displayed relatively higher signals for miR-31-3p, miR-146b-3p, several let-7 members, and selected miR-181 isoforms, whereas SHED-EV-S showed a marked relative increase of miR-486-3p; miR-21, miR-99/100, and miR-205 were broadly comparable between phases. These findings indicate that culture growth phase is a practical design lever that orients SHED-EV cargo and function, supporting phase-matched formulations for adjunctive transurethral applications and motivating in vivo validation and manufacturing-oriented quality controls. Full article
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19 pages, 2893 KB  
Article
Reconstructing Historical Atmospheres: Creating Sensory Trails for Heritage Sites
by Jieling Xiao and Michael Butler
Architecture 2026, 6(1), 3; https://doi.org/10.3390/architecture6010003 - 24 Dec 2025
Viewed by 322
Abstract
Trails in heritage sites are useful ways to engage visitors with the place. Sensory trails proposed in this paper, engaged with the sensory walking method, are designed purposefully to engage the multi-sensory features onsite with prompts to link to the historic sensory elements [...] Read more.
Trails in heritage sites are useful ways to engage visitors with the place. Sensory trails proposed in this paper, engaged with the sensory walking method, are designed purposefully to engage the multi-sensory features onsite with prompts to link to the historic sensory elements that have historic and cultural meanings to the heritage sites. Two questions are asked: (1) What process can we follow to design sensory heritage trails? (2) What criteria can be used to evaluate and guide the sensory features on site and from historic documentations? Taking design research as the overarching methodology, this paper reflects on the creation of two sensory trails, Sensing Beyond the Roundhouse and Sensing Around the Anglesey Column, following the Double Diamond framework developed by UK Design Council. An iterative design framework was developed, beginning with the identification of constraints and sensory opportunities through site observations, document analysis, and stakeholder interviews, which leads to interpretations of sensory features to shape storylines and route planning informed by user analysis. It is followed by representing the trails through sensory maps and other low-cost creative formats and then validating proposed trails with communities and stakeholders via pilot walks and feedback sessions. Four criteria are generated to assess sensory features based on engagement and authenticity: their contribution to the authentic historic atmosphere of the site; their ability to trigger imagination and evoke nostalgia; their distinctiveness and relevance to the site’s heritage narratives; and their capacity to encourage physical interaction and embodied engagement. The discussion part argues that sensory trails can be used as place-based strategies to inform urban planning and development around the heritage site through three pathways: catalyst for improvements and developments, connect isolated heritage sites, generate place-based knowledge. Full article
(This article belongs to the Special Issue Atmospheres Design)
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34 pages, 1353 KB  
Article
Wayfinding with Impaired Vision: Preferences for Cues, Strategies, and Aids (Part II—Perspectives from Orientation and Mobility Instructors)
by Dominique P. H. Blokland, Maartje J. E. van Loef, Nathan van der Stoep, Albert Postma and Krista E. Overvliet
Brain Sci. 2026, 16(1), 6; https://doi.org/10.3390/brainsci16010006 - 20 Dec 2025
Viewed by 377
Abstract
Background/Objectives: People with visual impairments can participate in orientation and mobility (O&M) training to learn how to navigate to their desired destinations. Instructors adapt their approach to each individual client. However, assessments of client characteristics and resulting instructional adaptations are not standardised and [...] Read more.
Background/Objectives: People with visual impairments can participate in orientation and mobility (O&M) training to learn how to navigate to their desired destinations. Instructors adapt their approach to each individual client. However, assessments of client characteristics and resulting instructional adaptations are not standardised and may therefore vary. This study aimed to identify which individual differences instructors consider during O&M training and why. Methods: We conducted semi-structured qualitative interviews with 10 O&M instructors. Participants were asked to describe how they prepare for a training trajectory, and to describe a route they taught a specific client. Thematic analysis was used to determine instructional choices and the relevant client-specific factors. Results: We observed a common four-step instructional process in which clients are taught to notice, interpret, act upon, and anticipate relevant sensory cues until a destination is reached. Four main themes captured the individual differences impacting this process: Sensory modalities, Capacities and limits, Personal contextual characteristics, and Training approach. Conclusions: Instructors perceive route learning to be shaped by clients’ sensory abilities (even fluctuating within sensory modalities), mental and physical capacities (especially concentration and energy), and personal characteristics (especially age and anxiety). The dynamic social context in which training takes place (e.g., the instructor–client relationship) is shaped by individual differences between both clients and instructors. We speculate that trust-related themes (e.g., building confidence) may explain why certain client characteristics are emphasised by instructors, as they are associated with training outcomes. Full article
(This article belongs to the Special Issue Neuropsychological Exploration of Spatial Cognition and Navigation)
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