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28 Results Found

  • Review
  • Open Access
2 Citations
2,969 Views
12 Pages

What Are the Determinants of the Quality of Systematic Reviews in the International Journals of Occupational Medicine? A Methodological Study Review of Published Literature

  • Giuseppe La Torre,
  • Remigio Bova,
  • Rosario Andrea Cocchiara,
  • Cristina Sestili and ,
  • Anna Tagliaferri,
  • Simona Maggiacomo,
  • Camilla Foschi,
  • William Zomparelli,
  • Maria Vittoria Manai and
  • Alice Mannocci
  • + 9 authors+ 4 authors

Objective: The aim of this study was to evaluate the methodological quality of systematic reviews published in occupational medicine journals from 2014 to 2021. Methods: Papers edited between 2014 and 2021 in the 14 open access journals with the high...

  • Article
  • Open Access
16 Citations
5,114 Views
14 Pages

1 November 2020

Although earlier meta-analysis studies have provided evidence-based information useful for decision-making, debate regarding their quality continues. This study aimed to evaluate the quality of meta-analysis studies in the field of dance therapy (DT)...

(This article belongs to the Special Issue Physical Rehabilitation & Prevention in Sports Injuries)
  • Review
  • Open Access
5 Citations
6,710 Views
10 Pages

Impact of Extent of Resection on Overall Survival in Glioblastomas: An Umbrella Review of Meta-Analyses

  • Pemla Jagtiani,
  • Mert Karabacak,
  • Alejandro Carrasquilla,
  • Raymund Yong and
  • Konstantinos Margetis

25 October 2024

(1) Background: Glioblastoma (GBM) is the most common malignant brain tumor in adults. Due to a lack of level 1 evidence, there is no clear consensus on the optimal extent of resection to improve overall survival. This umbrella review aggregates exis...

  • Systematic Review
  • Open Access
10 Citations
5,800 Views
13 Pages

The Efficacy of Cognitive Remediation Therapy for Anorexia Nervosa: A Systematic Review of Systematic Reviews

  • Gloria Marchesi,
  • Davide Maria Cammisuli,
  • Michelle Semonella,
  • Gianluca Castelnuovo and
  • Giada Pietrabissa

24 January 2024

Background: Cognitive remediation therapy (CRT) for anorexia nervosa (AN) is an intervention specifically focused on addressing cognitive difficulties associated with the eating disorder. This systematic review of systematic reviews and meta-analysis...

(This article belongs to the Section Nutritional Neuroscience)
  • Article
  • Open Access
4 Citations
3,325 Views
15 Pages

Recommendations addressing screening for scoliosis differ substantially. Systematically developed guidelines are confronted by consensus and opinion-based statements. This paper elaborates on the issue of the standards of development and reporting of...

(This article belongs to the Section Adolescents)
  • Review
  • Open Access
20 Citations
8,361 Views
12 Pages

Outcome Comparison of Drug-Resistant Trigeminal Neuralgia Surgical Treatments—An Umbrella Review of Meta-Analyses and Systematic Reviews

  • Alessandro Rapisarda,
  • Marco Battistelli,
  • Alessandro Izzo,
  • Manuela D’Ercole and ,
  • Quintino Giorgio D’Alessandris,
  • Filippo Maria Polli,
  • Samuele Santi,
  • Renata Martinelli and
  • Nicola Montano
  • + 4 authors+ 0 author

Medical treatment for trigeminal neuralgia (TN) is not always a feasible option due to a lack of full response or adverse effects. Open surgery or percutaneous procedures are advocated in these cases. Several articles have compared the results among...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Review
  • Open Access
28 Citations
6,800 Views
15 Pages

2 December 2021

The purpose of this study was to summarize and evaluate evidence on the effectiveness of perioperative magnesium as an adjuvant for postoperative analgesia. We conducted an umbrella review of the evidence across systematic reviews and meta-analyses o...

(This article belongs to the Special Issue Individual Evaluation, Management and Outcome in Perioperative Medicine)
  • Review
  • Open Access
1,658 Views
11 Pages

25 January 2024

Background: Chronic conditions, especially pain conditions, have a very significant impact on quality of life and on workplaces. Workplace interventions for chronic conditions are heterogenous, multidimensional, and sometimes poorly evidenced. The Jo...

(This article belongs to the Special Issue Review Special Issue Series: Recent Advances in Anesthesiology)
  • Article
  • Open Access
18 Citations
6,312 Views
8 Pages

Association between Work and Chronic Obstructive Pulmonary Disease (COPD)

  • H. F. Van der Molen,
  • G. J. De Groene,
  • C. T. J. Hulshof and
  • M. H. W. Frings-Dresen

9 October 2018

To support occupational physicians in their assessment and notification of occupational diseases, diagnostic registration guidelines are developed with information about associations between work-related risk factors and diseases. The objective of th...

(This article belongs to the Special Issue Occupational Diseases: From Cure to Prevention)
  • Review
  • Open Access
11 Citations
5,770 Views
15 Pages

A Cross-Sectional Study Based on Forty Systematic Reviews of Foods with Function Claims (FFC) in Japan: Quality Assessment Using AMSTAR 2

  • Hiroharu Kamioka,
  • Hideki Origasa,
  • Kiichiro Tsutani,
  • Jun Kitayuguchi and ,
  • Takahiro Yoshizaki,
  • Mikiko Shimada,
  • Yasuyo Wada and
  • Hiromi Takano-Ohmuro
  • + 3 authors+ 0 author

24 April 2023

Background: The Foods with Function Claims (FFC) was introduced in Japan in April 2015 to make more products available that are labeled with health functions. The products’ functionality of function claims must be explained by scientific eviden...

(This article belongs to the Special Issue Databases, Nutrition and Human Health)
  • Review
  • Open Access
16 Citations
15,133 Views
17 Pages

Botulinum Toxin for Bruxism: An Overview

  • Manuella Salm Coelho,
  • Júlia Meller Dias de Oliveira,
  • Helena Polmann,
  • Patrícia Pauletto and ,
  • Cristine Miron Stefani,
  • Lara Catarine De Luca Maciel and
  • Graziela De Luca Canto
  • + 2 authors+ 0 author

16 May 2025

This overview aimed at assessing botulinum toxin type A (BoNT-A)’s effectiveness in managing bruxism compared to a placebo, the absence of treatment, or other interventions in adults. Only systematic reviews (SRs), with or without a meta-analys...

(This article belongs to the Section Bacterial Toxins)
  • Systematic Review
  • Open Access
2 Citations
5,807 Views
16 Pages

Systematic Review and Meta-Analysis of Cardiac MRI T1 and ECV Measurements in Pre-Heart Failure Populations

  • Robert S. Doyle,
  • Ross Walsh,
  • Jamie Walsh,
  • Hugo C. Temperley and ,
  • John McCormick and
  • Gerard Giblin
  • + 1 author+ 0 author

13 August 2025

Background/Objectives: Heart failure (HF) often develops from a prolonged asymptomatic phase where early detection could prevent progression. Pre-heart failure (pre-HF) populations—those with risk factors (Stage A) or subclinical myocardial cha...

(This article belongs to the Topic Biomarkers in Cardiovascular Disease—Chances and Risks, 2nd Volume)
  • Review
  • Open Access
12 Citations
16,127 Views
16 Pages

The Effectiveness of Community Occupational Therapy Interventions: A Scoping Review

  • Maria-Francesca Estrany-Munar,
  • Miguel-Ángel Talavera-Valverde,
  • Ana-Isabel Souto-Gómez,
  • Luis-Javier Márquez-Álvarez and
  • Pedro Moruno-Miralles

Background: This review aims to evaluate the level of scientific evidence for the effectiveness of Community Occupational Therapy interventions. Methods: A systematic review was used to analyze and synthesize the studies collected. The databases of C...

  • Systematic Review
  • Open Access
1,122 Views
15 Pages

14 May 2026

Background: Growing evidence suggests that vitamin D plays a role in the pathophysiology of childhood asthma. However, its effectiveness in reducing asthma exacerbations and improving asthma-related outcomes remains controversial. Methods: We systema...

(This article belongs to the Special Issue Vitamins and Human Health: 3rd Edition)
  • Review
  • Open Access
5 Citations
1,145 Views
24 Pages

Sustainability of Oral Healthcare Services: A Mapping Review

  • Diego R. Aguilar,
  • Nathalia S. Guimarães,
  • Alex Junio S. Cruz,
  • Andre Luiz Brasil V. Pinto and ,
  • Isabela A. Pordeus and
  • Mauro Henrique N. G. Abreu
  • + 1 author+ 0 author

22 November 2025

Background/Objectives: Environmental sustainability is increasingly recognized as a key component of healthcare governance, and dentistry represents a high-impact subsector due to its intensive use of materials, resources, and biosafety-driven dispos...

  • Systematic Review
  • Open Access
2 Citations
2,040 Views
30 Pages

This study reviews 33 meta-analyses and systematic reviews on Computational Thinking (CT), focusing on research quality, intervention effectiveness, and content. Quality assessment of included studies was conducted using the AMSTAR 2 tool. The meta-a...

  • Feature Paper
  • Review
  • Open Access
15 Citations
9,287 Views
17 Pages

The Impact of Ketamine on Outcomes in Acute Pain Management: An Umbrella Review

  • Dmitriy Viderman,
  • Diyara Mukazhan,
  • Kamilla Kapessova,
  • Meiram Tungushpayev and
  • Rafael Badenes

17 December 2024

Background/Objectives: Ketamine offers effective pain relief with fewer side effects than traditional analgesics, making it a promising alternative for acute pain treatment. However, further research is needed to fully assess its role in perioperativ...

(This article belongs to the Special Issue Advances in Postoperative Pain Management and Chronic Postoperative Pain: Part II)
  • Review
  • Open Access
43 Views
33 Pages

4 November 2026

Generative artificial intelligence (GenAI) promises personalized support, feedback and efficiency in higher education, but raises concerns about cognitive dependency, unequal capability, assessment validity, privacy, environmental cost and commercial...

(This article belongs to the Special Issue Generative AI and the Future of Pedagogical Sustainability: Balancing Creative Innovation with Ethical Fairness)
  • Review
  • Open Access
15 Citations
24,212 Views
19 Pages

Omega-3 Polyunsaturated Fatty Acids and Cognitive Decline in Adults with Non-Dementia or Mild Cognitive Impairment: An Overview of Systematic Reviews

  • Maria Inês Barros,
  • Teresa Brandão,
  • Susana Couto Irving,
  • Paula Alves and ,
  • Filomena Gomes and
  • Marta Correia
  • + 1 author+ 0 author

19 September 2025

Background/Objectives: As global aging accelerates, prevalence of mild cognitive impairment (MCI) continues to rise, challenging healthcare systems and diminishing older adults’ quality of life. There is great interest in better understanding t...

(This article belongs to the Special Issue Food as Medicine for Brain and Other Tissues)
  • Review
  • Open Access
35 Citations
6,792 Views
19 Pages

Quality of Systematic Reviews of the Foods with Function Claims in Japan: Comparative Before- and After-Evaluation of Verification Reports by the Consumer Affairs Agency

  • Hiroharu Kamioka,
  • Kiichiro Tsutani,
  • Hideki Origasa,
  • Takahiro Yoshizaki and ,
  • Jun Kitayuguchi,
  • Mikiko Shimada,
  • Yasuyo Wada and
  • Hiromi Takano-Ohmuro
  • + 3 authors+ 0 author

12 July 2019

Background: In Japan, a new type of foods with health claims, called Foods with Function Claims (FFC), was introduced in April 2015 in order to make more products available that are clearly labeled with certain health functions. Regarding substantiat...

  • Systematic Review
  • Open Access
4 Citations
2,393 Views
29 Pages

A Literature Review and Meta-Analysis on the Potential Use of miR-150 as a Novel Biomarker in the Detection and Progression of Multiple Sclerosis

  • Vasile Calin Arcas,
  • Anca Maria Fratila,
  • Doru Florian Cornel Moga,
  • Iulian Roman-Filip and ,
  • Ana-Maria Cristina Arcas,
  • Corina Roman-Filip and
  • Mihai Sava
  • + 2 authors+ 0 author

31 July 2024

Background: MicroRNA-150 (miR-150) plays a critical role in immune regulation and has been implicated in autoimmune diseases like Multiple Sclerosis (MS). This review aims to evaluate miR-150’s potential as a biomarker for MS, necessitating thi...

(This article belongs to the Special Issue Clinical Updates and Challenges of Multiple Sclerosis and Related Disorders)
  • Systematic Review
  • Open Access
22 Citations
7,312 Views
14 Pages

Redefining Knee Arthroplasty: Does Robotic Assistance Improve Outcomes Beyond Alignment? An Evidence-Based Umbrella Review

  • Fernando García-Sanz,
  • María Dolores Sosa-Reina,
  • Gonzalo Jaén-Crespo,
  • Ángel González-de-la-Flor and ,
  • Jorge Hugo Villafañe and
  • Carlos Romero-Morales
  • + 1 author+ 0 author

9 April 2025

Background: Robotic-assisted total knee arthroplasty (rTKA) has been introduced to improve surgical precision and alignment in knee replacement procedures. However, its impact on clinical outcomes, pain relief, and cost-effectiveness remains debated....

(This article belongs to the Special Issue Musculoskeletal Imaging and Intervention)
  • Review
  • Open Access
15 Citations
7,867 Views
13 Pages

Robot-Assisted Upper Limb Training for Patients with Multiple Sclerosis: An Evidence-Based Review of Clinical Applications and Effectiveness

  • Sofia Straudi,
  • Marco Tramontano,
  • Emanuele Francesco Russo,
  • Luca Perrero and ,
  • Michela Agostini,
  • Marialuisa Gandolfi,
  • Irene Aprile,
  • Matteo Paci,
  • Emanuela Casanova and
  • Working Group Upper Limb “CICERONE” Italian Consensus Conference on Robotic Rehabilitation
  • + 35 authors+ 30 authors

27 December 2021

Upper extremities limitation is a common functional impairment in patients with Multiple Sclerosis (PwMS). Novel technological devices are increasingly used in neurorehabilitation to support motor function improvement and the quantitative assessment...

(This article belongs to the Special Issue The Present and Future of Robotic Technology in Rehabilitation)
  • Systematic Review
  • Open Access
32 Citations
7,727 Views
16 Pages

Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review

  • Giovanni Morone,
  • Alessandro de Sire,
  • Alex Martino Cinnera,
  • Matteo Paci and ,
  • Luca Perrero,
  • Marco Invernizzi,
  • Lorenzo Lippi,
  • Michela Agostini,
  • Irene Aprile and
  • Sofia Straudi
  • + 36 authors+ 31 authors

10 December 2021

The upper extremities limitation represents one of the essential functional impairments in patients with cervical spinal cord injury. Electromechanics assisted devices and robots are increasingly used in neurorehabilitation to help functional improve...

(This article belongs to the Special Issue Innovations in Neurorehabilitation and Neuroplasticity)
  • Review
  • Open Access
7 Citations
4,190 Views
22 Pages

Actual Data on Essential Trace Elements in Parkinson’s Disease

  • Cristina Popescu,
  • Constantin Munteanu,
  • Aura Spînu,
  • Ioana Andone and ,
  • Roxana Bistriceanu,
  • Ruxandra Postoiu,
  • Andreea Suciu,
  • Sebastian Giuvara,
  • Andreea-Iulia Vlădulescu-Trandafir and
  • Gelu Onose
  • + 8 authors+ 3 authors

29 May 2025

“Sola dosis facit venenum” (Paracelsus). Essential trace elements, crucial for maintaining neuronal function, have their dysregulation increasingly correlated with neurodegenerative disorders, particularly Parkinson’s disease (PD)....

(This article belongs to the Special Issue Trace Minerals in Human Health: Hot Topics and Information Update)
  • Review
  • Open Access
77 Views
44 Pages

Background: Unplanned ICU readmissions are associated with adverse outcomes, including mortality. However, evidence on risk factors for readmission remains inconclusive. This scoping review was conducted to summarize risk factors for unplanned ICU re...

(This article belongs to the Section Molecular and Translational Medicine)
  • Systematic Review
  • Open Access
4 Citations
1,586 Views
16 Pages

Reconsidering Anesthesia in Lumbar Surgery: An Umbrella Review of Awake Versus General Anesthesia

  • Favour C. Ononogbu-Uche,
  • Carl Tchoumi,
  • Nolan M. Stubbs,
  • Arnav Sharma and ,
  • Raymond J. Gardocki,
  • Alok Sharan,
  • Muhammad M. Abd-El-Barr,
  • Ernest E. Braxton and
  • Awake Spine Research Group
  • + 4 authors+ 0 author

24 November 2025

Background/Objectives: Lumbar degenerative disease drives numerous elective spine surgeries, and anesthetic choice significantly influences airway risk, hemodynamics, analgesia, mobilization, and recovery. Interest in awake lumbar surgery, typically...

(This article belongs to the Special Issue New Concepts in Minimally Invasive Spine Surgery)
  • Review
  • Open Access
4 Citations
1,574 Views
29 Pages

Percutaneous Cryoneurolysis for Upper Limb Spasticity: A Systematic Scoping Review of Current Evidence, Safety Profile, and Implications for Hand and Upper Extremity Practice

  • Marco Passiatore,
  • Luciano Maria Bissolotti,
  • Marta Starnoni,
  • Luca Pecori and ,
  • Anna Paola D’Apolito,
  • Francesco De Santis and
  • Rocco De Vitis
  • + 2 authors+ 0 author

Background/Objectives: Percutaneous cryoneurolysis (CNL) has emerged as a minimally invasive neuromodulatory technique for focal spasticity management, with growing international clinical adoption since 2018. Its application to upper limb motor nerve...

(This article belongs to the Special Issue Innovation in Hand Surgery)