Search Results (751)

The rapid growth of e-commerce demands innovative solutions for resilient and sustainable supply chains. This study explores the role of AI-driven demand forecasting (AIDF) and AI-driven waste reduction (AIDWR) in enhancing supply chain efficiency, minimizing operational waste, and fostering sustainability. Analyzing data from 539 samples via PLS-SEM, the findings highlight how AIDF optimizes demand accuracy, reduces overproduction, and minimizes stockouts, while AIDWR lowers resource consumption and mitigates environmental impacts. Operational Waste Reduction mediates AI’s effectiveness, aligning efficiency with sustainability goals and promoting adaptable, environmentally conscious supply chains. These insights guide e-commerce managers in leveraging AI for resilience and sustainable growth. The study underscores the transformative potential of AI to meet dual objectives of operational excellence and sustainability. Full article

This study presents a comprehensive bibliographic and semantic analysis of 3957 scientific publications on artificial intelligence (AI) in government and public administration. Using an integrated text- and network-based approach, we identify the main thematic areas and conceptual orientations shaping this rapidly expanding field. The analysis reveals a research landscape that spans AI-driven administrative transformation, digital innovation, ethics and accountability, citizen trust, sustainability, and domain-specific applications such as healthcare and education. Across these themes, policy-oriented and conceptual contributions remain prominent, while empirical and technical studies are increasingly interwoven, reflecting growing interdisciplinarity and methodological consolidation. By clarifying how AI research aligns with governance values and institutional design, this study offers actionable insights for policymakers and public managers seeking to navigate responsible public-sector AI adoption. Overall, the findings indicate that AI-for-Government research is moving from fragmented debates toward a more integrated, implementation-relevant knowledge base centered on trustworthy and value-aligned digital-era governance. Full article

Machine Learning and Knowledge Extraction have evolved from algorithmic tools for pattern recognition into a unifying foundational scientific framework underpinning virtually all of today’s groundbreaking advances, enabling systematic discovery, interpretation and understanding across domains. This paper introduces a comprehensive research agenda that defines currently the future of innovation in Artificial Intelligence. We identify ten interrelated research frontiers that collectively map the transition from data-driven learning to knowledge-centric, trustworthy, and sustainable intelligence. These frontiers span the full spectrum of future AI research: from physics-informed and hybrid architectures that embed causality and domain knowledge, to multimodal and embedded intelligence that ground AI in real-world contexts; from interpretable and responsible design principles that ensure transparency and fairness, to safe and sustainable deployment in open-world environments. Together, these directions delineate a coherent roadmap toward AI systems that not only predict but also explain, reason, and collaborate. Future AI can be seen as a new member of your research lab, an active participant in knowledge creation, driven by interdisciplinary integration, global cooperation, ethical responsibility, and human oversight. By embedding principles of transparency, sustainability, and societal alignment from the outset, we envision AI as both a catalyst for scientific discovery and a cornerstone of responsible technological progress. Full article

The global transition from internal combustion engines (ICEs) to hybrid (HEVs) and electric vehicles (EVs) is fundamentally reshaping lubricant design requirements, driven by evolving thermal demands, electrical constraints, and material compatibility challenges. Conventional ICE lubricants are primarily formulated to withstand high operating temperatures, mechanical stresses, and combustion-derived contaminants through established additive chemistries such as zinc dialkyldithiophosphate (ZDDP), with thermal stability and wear protection as dominant considerations. In contrast, HEV lubricants must accommodate frequent start–stop operation, pronounced thermal cycling, and fuel dilution while maintaining performance across coupled mechanical and electrical subsystems. EV lubricants represent a paradigm shift, where requirements extend beyond tribological protection to include electrical insulation and conductivity control, thermal management of electric motors and battery systems, and compatibility with copper windings, polymers, elastomers, and advanced coatings, alongside mitigation of noise, vibration, and harshness (NVH). This review critically examines lubricant behavior, formulation strategies, and performance requirements across ICE, HEV, and EV powertrains, with specific emphasis on heat transfer, electrical performance, and lubricant–material interactions, covering mineral, synthetic, and bio-based fluids. Additionally, regulatory drivers, sustainability considerations, and emerging innovations such as nano-additives, multifunctional and smart lubricants, and AI-assisted formulation are discussed. By integrating recent research into industrial practice, this work highlights the increasingly interdisciplinary role of tribology in enabling efficient, durable, and sustainable mobility for next-generation automotive systems. Full article

Background: Artificial Intelligence (AI) has emerged as a transformative tool in in vitro fertilization (IVF) as it has done in other sectors. In IVF, AI offers advancements in embryo selection, treatment personalization, and outcome prediction. It does so by leveraging deep learning and computer vision, as well as AI-driven platforms such as ERICA, iDAScore, and IVY where the goal is to address the limitations of traditional embryo assessment. Key amongst them are the issues of subjectivity, labor intensity, and limited predictive power. Despite rapid technological progress, the integration of AI into routine IVF practice faces key challenges. These are issues related to clinical validation, ethical dilemmas, and workflow adaptation. Rationale/Objectives: This review synthesizes current evidence to evaluate the role of AI in IVF, focusing on six critical dimensions: (1) the evolution of AI from traditional embryology to algorithmic assessment, (2) clinical validation and regulatory considerations, (3) limitations and ethical challenges, (4) pathways for clinical integration, (5) real-world applications and outcomes, and (6) future directions and policy recommendations. The objective is to provide a comprehensive roadmap for the responsible adoption of AI in reproductive medicine. Outcomes: AI demonstrates significant potential to improve the precision and efficiency of IVF. Studies report that AI models can achieve 10 to 25% higher accuracy in predicting embryo viability and implantation potential compared to traditional morphological assessment by embryologists. This enhanced predictive power supports more consistent embryo ranking, facilitates elective single-embryo transfer (eSET) strategies, and is associated with 30 to 50% reductions in embryologist workload per embryo cohort. Early adopters report promising trends. However, large-scale randomized controlled trials have yet to conclusively demonstrate a statistically significant increase in live birth rates per transfer compared to expert embryologist selection. The most immediate and evidenced value of AI lies in hybrid decision-making models. This is where it augments embryologists by providing data-driven, objective support, thereby standardizing workflows and reducing subjectivity. Wider Implications: The sustainable integration of AI into IVF banks on three key aspects: robust evidence generation, interdisciplinary collaboration, and global standardization. To foster these, policymakers ought to establish regulatory frameworks for transparency and bias mitigation. On their part, clinicians need training to interpret AI outputs critically. Ethically, safeguarding patient trust and equity is non-negotiable. Future innovations, mainly AI-enhanced genomics and real-time monitoring, could further personalize care. However, their success depends on addressing current limitations. By balancing innovation with ethical vigilance, AI holds the potential to revolutionize IVF while upholding the highest standards of patient care. Full article

Artificial Intelligence plays an exponentially growing role in producing data-driven policy insights. In this policy-oriented case study, AI technology is examined as a necessary coordination node through evidence-based and data-enhanced policies, which can efficiently balance the processes of different and possibly competing sectors, such as agriculture and tourism. The focus is on the NUTS 1 region of the Aegean Islands and Crete (EL4) in Greece. The analysis aims to create a viable and resilient ecosystem of environmental, economic and social sustainability through innovation. Applying a “Growth Pole Theory” approach, key public administration frameworks like the European Interoperability Framework (EIF) and TAPIC (Transparency, Accountability, Participation, Integrity, Capacity) governance framework are discussed and analysed to structure the AI deployment and policy considerations for sustainable development. The paper argues in favour of AI’s transformative potential across both the agriculture and tourism sectors. Full article

Background: Recent advancements in blood transfusion and transfusion medicine have increasingly integrated innovative technologies, including artificial intelligence (AI), machine learning, and computational intelligence. Despite numerous reviews on these topics, a comprehensive synthesis of the existing evidence is lacking. Objective: This narrative review of reviews aims to summarize and critically appraise the current literature on AI-driven and emerging technological approaches in blood transfusion, providing a structured overview for researchers and clinicians. Methods: A total of 19 reviews were selected through a systematic search strategy. Studies were assessed for methodological quality, scope, and clinical relevance, using adapted criteria from narrative review checklists. Data were extracted regarding the type of technology, application in transfusion medicine, study population, and reported outcomes. Results: The included reviews highlight several key domains: AI-assisted prediction of transfusion requirements, automated blood typing and crossmatching, advanced monitoring of blood products, and integration of computational models in blood banking workflows. Most studies reported promising applications but revealed substantial heterogeneity in methods, limited clinical validation, and variable reporting quality. Conclusions: AI and emerging technologies offer significant potential to improve the safety, efficiency, and personalization of blood transfusion. However, standardization of study designs, comprehensive validation, and robust reporting are essential to translate these innovations into routine clinical practice. This review of reviews provides a structured synthesis to guide future research and implementation strategies in transfusion medicine. Full article

Background/Objectives: HER2-low breast cancer has emerged as a clinically meaningful category that challenges the historical HER2-positive versus HER2-negative classification. Although not defined as a distinct biological subtype, HER2-low tumors exhibit unique clinicopathological features and differential sensitivity to novel antibody–drug conjugates. Accurate identification remains difficult due to limitations in immunohistochemistry performance, inter-observer variability, intratumoral heterogeneity, and dynamic shifts in HER2 expression over time. This review synthesizes current evidence on the biological and clinical characteristics of HER2-low breast cancer and evaluates emerging diagnostic innovations, with emphasis on liquid biopsy approaches and evolving technologies that may enhance diagnostic accuracy and monitoring. Methods: A narrative literature review was conducted, examining tissue-based HER2 testing, liquid biopsy modalities, including circulating tumor cells, circulating nucleic acids, extracellular vesicles, and soluble HER2 extracellular domains, and applications of artificial intelligence (AI) across histopathology and multimodal diagnostic systems. Results: Liquid biopsy technologies offer minimally invasive, real-time assessment of HER2 dynamics and may overcome fundamental limitations of tissue-based assays. However, these platforms require rigorous analytical validation and face regulatory and standardization challenges before widespread clinical adoption. Concurrently, AI-enhanced histopathology and multimodal diagnostic systems improve reproducibility, refine HER2 classification, and enable more accurate prediction of treatment response. Emerging biosensor- and AI-enabled monitoring frameworks further support continuous disease evaluation. Conclusions: HER2-low breast cancer sits at the intersection of evolving pathology and technological innovation. Integrating liquid biopsy platforms with AI-driven diagnostics has the potential to advance precision stratification and guide personalized therapeutic strategies for this expanding patient subgroup. Full article

The causal analysis of historical aviation accidents documented in investigation reports is important for the design, manufacture, operation, and maintenance of aircraft. However, given that most accident data are unstructured or semi-structured, identifying and extracting causal information remain labor intensive and inefficient. This gap is further deepened by tasks, such as system identification from component information, that require extensive domain-specific knowledge. In addition, there is a consequential demand for causation pattern analysis across multiple accidents and the extraction of critical causation chains. To bridge those gaps, this study proposes an aviation accident causation and relation analysis framework that integrates prompt engineering with a retrieval-augmented generation approach. A total of 343 real-world accident reports from the NTSB were analyzed to extract causation factors and their interrelations. An innovative causation classification schema was also developed to cluster the extracted causations. The clustering accuracy for the four main causation categories—Human, Aircraft, Environment, and Organization—reached 0.958, 0.865, 0.979, and 0.903, respectively. Based on the clustering results, a causation knowledge graph for aviation accidents was constructed, and by designing a set of safety evaluation indicators, “pilot—decision error” and “landing gear system malfunction” are identified as high-risk causations. For each high-risk causation, critical combinations of causation chains are identified and “Aircraft operator—policy or procedural deficiency/pilot—procedural violation/Runway contamination → pilot—decision error → pilot procedural violation/32 landing gear/57 wings” was identified as the critical causation combinations for “pilot—decision error”. Finally, safety recommendations for organizations and personnel were proposed based on the analysis results, which offer practical guidance for aviation risk prevention and mitigation. The proposed approach demonstrates the potential of combining AI techniques with domain knowledge to achieve scalable, data-driven causation analysis and strengthen proactive safety decision-making in aviation. Full article

Enzyme engineering drives innovation in biotechnology, medicine, and industry, yet conventional approaches remain limited by labour-intensive workflows, high costs, and narrow sequence diversity. Artificial intelligence (AI) is revolutionising this field by enabling rapid, precise, and data-driven enzyme design. Machine learning and deep learning models such as AlphaFold2, RoseTTAFold, ProGen, and ESM-2 accurately predict enzyme structure, stability, and catalytic function, facilitating rational mutagenesis and optimisation. Generative models, including ProteinGAN and variational autoencoders, enable de novo sequence creation with customised activity, while reinforcement learning enhances mutation selection and functional prediction. Hybrid AI–experimental workflows combine predictive modelling with high-throughput screening, accelerating discovery and reducing experimental demand. These strategies have led to the development of synthetic “synzymes” capable of catalysing non-natural reactions, broadening applications in pharmaceuticals, biofuels, and environmental remediation. The integration of AI-based retrosynthesis and pathway modelling further advances metabolic and process optimisation. Together, these innovations signify a shift from empirical, trial-and-error methods to predictive, computationally guided design. The novelty of this work lies in presenting a unified synthesis of emerging AI methodologies that collectively define the next generation of enzyme engineering, enabling the creation of sustainable, efficient, and functionally versatile biocatalysts. Full article

Rare earth elements (REE) are vital for renewable energy, electronics, and advanced technologies; however, the process-related evolution of REE research has not been systematically quantified. This study conducts the first large-scale bibliometric analysis of 76,768 REE-related publications (1975–2024) from Web of Science, using the Cross-Disciplinary Publication Index (CDPI) and Technology–Economic Linkage Model (TELM). Results reveal three development phases: publication growth from <300 (1975–1990) to >5000 after 2008, driven by China’s export restrictions and the global clean energy transition; China leads with 24.1% of publications, followed by the U.S. (11.7%) and Germany (6.4%). Interdisciplinary mapping identifies materials science as the central field (CDPI = 0.81) linked to nanotechnology (0.75) and environmental science (0.66). Four thematic clusters dominate: (i) deposit geology, (ii) material applications, (iii) green extraction technologies, and (iv) circular economy strategies. Recent emphasis on sustainable practices and unconventional sources—such as phosphorites, bauxite, coal fly ash, and urban mining—reflects a shift toward green innovation. The findings guide policies to diversify REE supply through unconventional deposits (~50 Mt coal-hosted REE), eco-friendly extraction, and recycling. Future priorities include AI-driven exploration, lifecycle assessment of secondary sources, and stronger global collaboration to secure resilient, sustainable REE supply chains. Full article

Taiwan’s strategic focus in digital healthcare has been officially integrated into national industrial policy and identified as a crucial application area for artificial intelligence (AI) and next-generation communication technologies. As the healthcare sector undergoes rapid digital transformation, digital healthcare technologies have emerged as essential tools for improving medical quality and efficiency. Leveraging the extensive coverage of its National Health Insurance (NHI) system and its strengths in Information and Communications Technology (ICT), Taiwan also benefits from the robust research capacity of universities and hospitals. Government-driven regulatory reforms and infrastructure initiatives are further accelerating the advancement of the NHI MediCloud system and the broader digital healthcare ecosystem. This article provides a comprehensive overview of smart healthcare development, highlighting government policy support and the R&D capabilities of universities, research institutes, and hospitals. It also examines the ICT industry’s participation in the development of smart healthcare ecosystems, such as Foxconn, Quanta, Acer, ASUS, Wistron, Qisda, etc. With strong data assets, technological expertise, and policy backing, Taiwan demonstrates significant potential in both AI innovation and smart healthcare applications, steadily positioning itself as a key player in the global healthcare market. Full article

Current food systems are highly complex, with interdependencies across regions, resources, and actors, and conventional food production is a major contributor to climate change. Transitioning to sustainable protein sources is therefore critical to meet the nutritional needs of a growing global population while reducing environmental pressures. Filamentous fungi present a promising solution by converting agro-industrial side streams into mycoproteins—nutrient-dense, sustainable proteins with a carbon footprint more than ten times lower than beef. This review evaluates the potential of mycoproteins derived from fungi cultivated on low-cost substrates, focusing on their role in advancing sustainable food systems. Evidence indicates that mycoproteins are rich in protein (13.6–71% dw), complete amino acids, fiber (4.8–25% dw), essential minerals, polyphenols, and vitamins while maintaining low fat and moderate carbohydrate content. Fermentation efficiency and product quality depend on substrate type, nutrient availability, and fungal strain, with advances in bioreactor design and AI-driven optimization enhancing scalability and traceability. Supported by emerging regulatory frameworks, mycoproteins can reduce reliance on animal-derived proteins, valorize agricultural by-products, and contribute to climate-resilient, nutritionally rich diets. Integration into innovative food products offers opportunities to meet consumer preferences while promoting environmentally sustainable, socially equitable, and economically viable food systems within planetary boundaries. Full article

The exponential growth in the usage of textual data across industries and data sharing across institutions underscores the critical need for frameworks that effectively balance data utility and privacy. This paper proposes an innovative agentic AI-based framework specifically tailored for textual data, integrating user-driven qualitative inputs, differential privacy, and generative AI methodologies. The framework comprises four interlinked topics: (1) A novel quantitative approach that translates qualitative user inputs, such as textual completeness, relevance, or coherence, into precise, context-aware utility thresholds through semantic embedding and adaptive metric mapping. (2) A differential privacy-driven mechanism optimizing text embedding perturbations, dynamically balancing semantic fidelity against rigorous privacy constraints. (3) An advanced generative AI approach to synthesize and augment textual datasets, preserving semantic coherence while minimizing sensitive information leakage. (4) An adaptable dataset-dependent optimization system that autonomously profiles textual datasets, selects dataset-specific privacy strategies (e.g., anonymization, paraphrasing), and adapts in real-time to evolving privacy and utility requirements. Each topic is operationalized via specialized agentic modules with explicit mathematical formulations and inter-agent coordination, establishing a robust and adaptive solution for modern textual data challenges. Full article

Smart Manufacturing Systems (SMSs) have evolved into intelligent, data-driven ecosystems that integrate cyber–physical systems, digital twins, and artificial intelligence to enhance efficiency, sustainability, and resilience. This review synthesises more than 250 recent studies across four domains: manufacturing technologies, systems management, sustainable production, and human–robot collaboration. In process optimisation, hybrid machine learning and genetic algorithms reduce surface roughness in machining by up to 35% and decrease energy use in additive manufacturing by 20–30%. In systems management, digital twins and reinforcement learning enable adaptive scheduling and predictive maintenance, increasing operational flexibility and reducing industrial downtime. Sustainability-oriented research shows that additive manufacturing can cut energy consumption by up to threefold compared with subtractive routes, while aluminium recycling and hot-forming processes lower life-cycle impacts. Furthermore, the integration of ISO 14001, ISO 50001, and ISO 14040 supports consistent environmental and energy performance assessment across sectors. Building on this evidence, the review critically examines recent developments in manufacturing technologies, systems management, sustainable practices, and human–robot collaboration, highlighting emerging paradigms such as explainable AI and human-centric design that strengthen safety, transparency, and resilience. Open challenges and research opportunities are outlined to guide future innovation toward intelligent, adaptive, and sustainable manufacturing systems. Full article