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  • Article
  • Open Access
3 Citations
1,780 Views
15 Pages

Theoretical Assessment of the Ligand/Metal/Quadruplex Recognition in the Non-Canonical Nucleic Acids Structures

  • Nikoleta Kircheva,
  • Stefan Dobrev,
  • Vladislava Petkova,
  • Snezhana Bakalova,
  • Jose Kaneti and
  • Silvia Angelova

17 August 2023

Quadruplexes (GQs), peculiar DNA/RNA motifs concentrated in specific genomic regions, play a vital role in biological processes including telomere stability and, hence, represent promising targets for anticancer therapy. GQs are formed by folding gua...