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Excess nutrients in wastewater pose significant environmental risks, highlighting the need for low-cost treatment strategies that enable their removal. This study evaluated the adsorption capacity of woodchip biochar, a widely available waste material, for phosphate (PO₄³⁻), nitrate (NO₃⁻), and ammonium (NH₄⁺) in raw and secondary-treated wastewater, and compared the results against those obtained using synthetic solutions. Approach to equilibrium was reached quicker for NH₄⁺ (≈20 min) than for NO₃⁻and PO₄³⁻ (≈40 min), with NH₄⁺ removal reaching up to 80% at a dosage of 20 g/L. Nutrient adsorption kinetics were best described by the pseudo-second-order model for the anionic species (NO₃⁻and PO₄³⁻), while the pseudo-first-order model provided a better fit for the cationic species NH₄⁺. The Freundlich isotherm provided a good fit to the equilibrium data for all species, indicating the presence of heterogeneous adsorption sites. SEM–EDX and FTIR analyses confirmed nutrient adsorption onto the biochar surface and highlighted the involvement of carboxyl and hydroxyl functional groups, with FTIR showing the greatest spectral changes for NH₄⁺. Adsorption tests using secondary-treated wastewater showed high removal efficiencies (100% PO₄³⁻, 25.4% NO₃⁻, 89.5% NH₄⁺), whereas performance in raw wastewater was poor (maximum 32% NH₄⁺). Overall, woodchip biochar demonstrates strong potential as a tertiary treatment material, and its nutrient-saturated form may be reused as fertiliser, supporting nutrient recovery within a circular-economy framework. Full article

Background/Objectives: Blood renin and electrolyte levels are associated with blood pressure and hypertension. While sex-specific effects of such factors have been investigated, exact comparisons of the factors between the sexes have been scarce. Methods: Using cohort data from the Korean Genome and Environmental Study (KoGES), the study population that did not receive any interventions for blood pressure was determined. Blood levels of renin and electrolytes, including sodium, potassium, chloride, and calcium, were used to test their relationship with hypertension and blood pressure. Confounding variables, including age, body mass index (BMI), waist-to-hip ratio, family history of hypertension, alcohol consumption, smoking, blood urea nitrogen, creatinine, protein, and albumin levels, were used for adjustment in the multiple regression analysis. Results: In the single-variable analysis, sodium levels were significantly higher in the female population, and showed strong associations in the multiple regression analysis. Blood potassium levels showed no significant sex-specific differences. Among these factors, renin showed the greatest significance in both the total population and sex-specific groups. Moreover, in the development of hypertension, the effect size of renin was significantly different between sexes. Additionally, BMI tended to show stronger associations in females. Conclusions: This study identified sex-specific differential effects of renin and other electrolytes that are important in the pathophysiology of blood pressure. These findings provide clues for the more precise management of hypertension. Full article

Background/Objectives: Socioeconomic stressors, such as financial strain, rising living costs, and perceived price burden, have gained relevance in the post-pandemic period and may adversely affect adolescent mental health. This study examined the association between subjective financial stress and symptoms of depression, anxiety, and emotional/behavioral difficulties among adolescents in Northern Italy. Methods: Data were obtained from the 2025 Corona and Psyche South Tyrol (COP-S) population survey. A total of 2554 adolescents aged 11–19 years and their parents participated; 1598 adolescents provided complete data for analyses of socioeconomic stressors (parent-reported Family Affluence Scale III, adolescent self-reported and parent proxy and self-reported burden due to price increases). Mental health outcomes included depressive symptoms (PHQ-2), generalized anxiety (SCARED-GAD), and emotional/behavioral difficulties (SDQ). Associations were assessed using chi-square tests, Kendall’s tau correlations, and two-factor ANOVA models. Results: Elevated depressive symptoms were present in 10.7% of adolescents, emotional/behavioral difficulties in 13.9%, and anxiety symptoms in 27.9% of adolescents. Female adolescents consistently showed higher symptom levels in all domains. Self-reported financial burden was the strongest and most consistent correlate of mental health problems, demonstrating small-to-moderate positive correlations with depressive symptoms (τ = 0.20, p < 0.001), emotional/behavioral difficulties (τ = 0.14, p < 0.001), and anxiety (τ = 0.25, p < 0.001). Parent-reported burden showed weaker and less consistent associations, and the Family Affluence Scale III was not significantly related to any of the mental health outcomes. ANOVA models indicated that adolescents’ own perception of financial burden significantly predicted anxiety levels in both age groups (11–14 and 15–19 years), whereas discrepancies between adolescent and parent burden perceptions were particularly relevant among younger adolescents. Conclusions: In this affluent European region, subjective financial strain, especially adolescents’ perception of burden due to rising prices, is a stronger determinant of depressive symptoms, anxiety, and psychosocial difficulties than parental burden reports or structural affluence indicators. Adolescents, especially females, appear to be particularly vulnerable. These findings underscore the importance of addressing subjective financial stress in adolescent mental health and public health strategies. Full article

The Finite State Model Predictive Control (FSMPC) of variable speed drives is the subject of many works in the recent literature. Many variants of FSMPC exist, each aiming at an aspect such as the complexity of the cost function, switching frequency, current quality, etc. In the case of multiphase drives, two popular variants are the monovector and multivector techniques. Despite past efforts to compare different techniques, the field must still reach a consensus regarding the relative merits of each one. This paper presents a new method to compare two families of FSMPC. The method is based on a reduced set of figures of merit using the current modulation index as the variable. The comparison is made for the equal usage of the power converter in terms of commutations. The results point to better values for the figures of merit for the monovector that, in addition, portrays more flexibility and better DC link usage. Full article

Recent research has documented both questionable and responsible research practices in published psychology research, but it is unclear which research practices psychology students engage in when graduating from their master’s program. In this study, we documented the prevalence of responsible and questionable research practices in 300 psychology master’s theses from Tilburg University, the Netherlands, and associated these practices with supervisor’s grading of the theses. Compared to authors of published scientific manuscripts, master’s students seemed to engage more in responsible research practices, conducted more power analyses, used larger sample sizes, reported fewer statistically significant results, and provided more detailed reporting of their results. However, statistical reporting errors were almost as common in master’s theses as they are in the published literature. We found no relationship between thesis grades and any of the responsible or questionable research practices. We also found no relationships among practices, suggesting that there is no unidimensional construct of “responsible scientific behavior”. Full article

In comparison to traditional wired and wireless communication scenarios, the underwater channel is peculiar, being significantly more difficult for communication and presenting a unique set of features and impairments, thus necessitating special care in selecting ad hoc encoding and modulation technologies to achieve successful transmissions. This process can be aided by simulations, which can be effectively carried out only using a good, detailed channel model validated through sea measurements. This study presents the results of a sea measurement campaign run in May 2024 off the Gulf of La Spezia, Italy, characterized by challenging shallow water conditions and the presence of shadow zones. The collected data is then used to model a simulated channel as faithful as possible to the one experienced during the sea trial. The obtained channel is then used to carry out a comparison of different forward error correction (FEC) codes, highlighting each scheme’s performance in our working context. Conclusive results show that a satisfactory simulated channel was obtained and that a different choice of FEC schemes could have improved the performance of the underwater acoustic communication. Full article

Preeclampsia is a serious pregnancy disorder of unknown etiology. One of its cellular hallmarks is increased mitochondrial dysfunction in placental tissue. Further investigation into this aspect may help elucidate the molecular basis of preeclampsia. A total of 24 pregnant women who delivered by cesarean section participated in the study: n = 13 controls and n = 11 diagnosed with preeclampsia. Maternal blood samples were collected to assess the biochemical profile, and demographic and clinical data were recorded. Placental trophoblast samples were processed to isolate mitochondria and perform molecular biology assays. Women with preeclampsia exhibited the characteristic clinical features of the disease, along with biochemical alterations consistent with an inflammatory process. A significant decrease (73%) in mitochondrial DNA (mtDNA) copy number in trophoblastic tissue and a reduction in citrate synthase (CS) activity (−51%) in cytotrophoblast mitochondria-enriched fractions were observed in preeclampsia, indicating mitochondrial dysfunction accompanied by a loss of functional mitochondrial mass. In addition, we detected a marked decrease in MnSOD levels (−32%), together with an increase in the LC3II/LC3I ratio (47%) in cytotrophoblast mitochondria-enriched fractions, supporting the presence of mitochondrial alterations and suggesting the possible activation of mitophagy specifically in this cell type. Moreover, coenzyme Q₁₀ (CoQ₁₀) levels were elevated by 31% in trophoblastic villi. A pronounced 2.5-fold increase in CoQ₁₀ normalized to CS activity (CoQ₁₀/CS) was detected specifically in cytotrophoblasts from preeclamptic placentas. Importantly, we did not observe these alterations in the syncytiotrophoblast. In conclusion, preeclampsia is associated with mitochondrial dysfunction and increased CoQ₁₀ levels normalized to CS activity, specifically in cytotrophoblast mitochondria, with findings being consistent with a possible involvement of mitophagy in this cell type. These findings suggest that cytotrophoblast mitochondrial metabolism may be more affected in preeclampsia compared with syncytiotrophoblasts, and that CoQ₁₀ accumulation together with the possible activation of mitophagy may represent cellular defense mechanisms. Due to the limitations of the study, it should be considered exploratory and hypothesis-generating, and its results should be regarded as preliminary. Full article

As agricultural labor shifted toward non-farm sectors and the farming population aged, innovative production arrangements became essential to sustain land productivity. While partial agricultural production chain management (PAPM) was widespread, the productivity impact of whole-process agricultural production chain management (WAPM)—a comprehensive model integrating all production stages—remained empirically underexplored. Using nationally representative panel data from the China Labor-force Dynamics Survey (CLDS, 2014–2018) for grain-producing households, this study estimates the differential impacts of WAPM and PAPM with a two-way fixed-effects (TWFE) model, supplemented by propensity score matching (PSM) as a robustness check. The results show that WAPM significantly enhanced land productivity. Notably, the effect size of WAPM (coefficient: 0.486) is substantially larger than that of PAPM (coefficient: 0.214), indicating that systematic integration of service chains offers superior efficiency gains over fragmented outsourcing. Mechanism analysis suggests that WAPM improves productivity primarily by alleviating labor constraints and mitigating the disadvantages of small-scale farming. Furthermore, heterogeneity analysis demonstrated that these benefits are amplified in major grain-producing regions and hilly areas. These findings support policies that facilitate a transition from single-link outsourcing toward whole-process integrated service provision. Full article

Background/Objectives: Sex and diabetes are important determinants of risk in heart failure with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF), yet their combined effects have not been systematically evaluated. This study examined how sex–diabetes phenotypes influence clinical characteristics and the risk of heart failure rehospitalization. Methods: We retrospectively analyzed 1018 HFmrEF/HFpEF patients (2019–2023), classified into four sex–diabetes phenotypes, and performed group comparisons. The primary endpoint was heart failure rehospitalization. Results: Over a mean follow-up of 1463 ± 496 days, 307 patients (30.1%) were rehospitalized for heart failure decompensation. The four phenotypes differed significantly in age, renal function, LV mass, LV dimensions, glycemia, and comorbidity burden (all p < 0.05). Men—particularly those with diabetes—had greater structural remodeling and higher prevalence of smoking, hypercholesterolemia, and atrial fibrillation. In univariate analysis, male sex, diabetes, smoking, NYHA class, lower TAPSE, and lower LVEF were associated with increased risk of rehospitalization. After adjustment for LVEF and NYHA class, male sex (HR 1.28; p = 0.035) and diabetes (HR 1.28; p = 0.036) remained independent predictors. Kaplan–Meier curves demonstrated a clear gradient in event-free survival (log-rank p = 0.015), with women without diabetes showing the best prognosis and diabetic men the worst. Conclusions: Sex and diabetes interact to define distinct risk profiles in HFmrEF/HFpEF. Women without diabetes represent a low-risk phenotype, whereas diabetic men exhibit the highest risk of recurrent heart failure decompensation. These findings support incorporating sex–diabetes phenotyping into routine risk stratification and personalized management. Full article

This study quantifies energy consumption and tank-to-wheel (TTW) emissions of urban buses under varying traffic conditions and passenger loads in Osnabrück, Germany, to support emission-aware route assessment in sustainable mobility applications. Exemplary bus trajectories were modeled on a representative 6.17 km route of line M5 (18 m articulated bus; diesel and battery-electric) within a 22.31 km² traffic net using the Simulation of Urban MObility (SUMO) software, and were calibrated with traffic sensor data. To assess the influence of trajectories in different traffic situations, three different 90 min scenarios were compared (morning peak, noon, night). Trajectory-based energy consumption and greenhouse gas emissions were compared by using the SUMO-implemented emission models HBEFA and PHEMlight, as well as data from the literature. Both diesel and electric buses showed variations in energy consumption depending on the traffic conditions, with generally lower energy consumption for electric propulsion. Temporal differences in the TTW emissions of the diesel bus were modest, with slightly higher morning values, while spatial analysis showed PM peaks in pedestrian zones, NO_x peaks during acceleration phases, and CO₂ increases after stops and in low-speed areas. The results provide spatially resolved TTW factors for integration into routing applications, excluding upstream and non-exhaust processes in line with the defined system boundary. Full article

Network intrusion detection is a key technology for ensuring cybersecurity. However, current methods face two major challenges: reliance on manual feature engineering, which leads to the loss of discriminative information, and the vulnerability of deep learning models to adversarial sample attacks. To address these issues, this paper proposes STS-AT, a novel network intrusion detection method that integrates structured tensors with adversarial training. The method consists of three core components: first, structured tensor encoding, which fully converts raw hexadecimal traffic into a numerical representation; second, a hierarchical deep learning model that combines CNN and LSTM networks to simultaneously learn spatial and temporal features of the traffic; third, a multi-strategy adversarial training method that enhances model robustness by adaptively adjusting the mix of adversarial samples in different training phases. Experiments on the CICIDS2017 dataset show that the proposed method achieves an accuracy of 99.6% in normal traffic classification, significantly outperforming classical machine learning baselines such as Random Forest (93.1%) and Support Vector Machine (84.7%). Crucially, under various adversarial attacks (FGSM, PGD, and DeepFool), the accuracy of an undefended model drops to as low as 24.4%, whereas after multi-strategy adversarial training, the defense accuracy rises above 96.8%. Meanwhile, the total training time is reduced by approximately 67.6%. These results verify that structured tensor encoding effectively preserves original traffic information, the hierarchical model achieves comprehensive feature learning, and multi-strategy adversarial training significantly improves training efficiency while ensuring robust defense effectiveness. Full article

Listeria monocytogenes (LM) contamination constitutes a paramount global threat to food safety, necessitating the urgent development of advanced, rapid, and non-destructive detection methodologies to ensure food security. This study successfully synthesized Bi₂WO₆ nanoflowers through optimized feed ratios of raw materials and further functionalized them with noble metal Au to construct a high-performance Au-Bi₂WO₆ composite nanomaterial. The composite exhibited high sensing performance toward acetoin, including high sensitivity (R_a/R_g = 36.9@50 ppm), rapid response–recovery kinetics (13/12 s), and excellent selectivity. Through UV-Vis diffuse reflectance spectroscopy (UV-Vis DRS) and X-ray photoelectron spectroscopy (XPS) characterizations, efficient electron exchange between Au and Bi₂WO₆ was confirmed. This electron exchange increased the initial resistance of the material, effectively enhancing the response value toward the target gas. Furthermore, the chemical sensitization effect of Au significantly increased the surface-active oxygen content, promoted gas–solid interfacial reactions, and improved the adsorption capacity for target gases. Compared to conventional turbidimetry, the Au-Bi₂WO₆ nanoflower-based gas sensor demonstrates superior practical potential, offering a novel technological approach for non-destructive and rapid detection of foodborne pathogens. Full article