1st Free Webinar on Biomolecules: Molecular Aspects of Cellular Dysfunction in Alzheimer's Disease—1 July 2020

Prof. Dr. Dmitry Lim

Guest Editor of Special Issue "Molecular Aspects of Cellular Dysfunction in Alzheimer's Disease"

Interests: calcium signaling; biosensors for calcium; neuroscience; neurodegeneration; Alzheimer’s disease; glial cells; astrocytes; CNS homeostasis

Dr. Sara Merlo

Guest Editor of Special Issue "Molecular Aspects of Cellular Dysfunction in Alzheimer's Disease"

Interests: Alzheimer’s disease; beta-amyloid toxicity; neurodegeneration; neuroinflammation; glial–neuron crosstalk; microglia; sirtuins; melatonin; estrogens

Dr. Simona Federica Spampinato

Guest Editor of Special Issue "Molecular Aspects of Cellular Dysfunction in Alzheimer's Disease"

Interests: neurodegeneration; neuroinflammation; BBB; astrocytes; endothelial cells; glial cells; beta amyloid; estrogens; sphingosine 1-phosphate; metabotropic glutamate receptors

Mr. Shun Fat Lau

Shun Fat Lau is currently a second-year Ph.D. student with the laboratory of Prof. Nancy Ip (The Hong Kong University of Science and Technology—HKUST). His research focuses on the functional roles of neuroimmunity in neurodegenerative diseases, such as Alzheimer’s disease (AD). Specifically, he investigates how modulating cytokine milieus, such as through interleukin-33 administration, in the central nervous system drives the functional state transition of microglia, resulting in the amelioration of AD pathology.

Dr. Maria Grazia Morgese

Maria Grazia Morgese is a Tenure Track Assistant Professor of Pharmacology with the Department of Clinical and Experimental Medicine of the University of Foggia, Italy. Her main research interests include the neurochemistry of neurodegenerative diseases. She is interested in the pharmacological modulation of neurotransmitter systems and the role of oxidative stress in neuropsychiatric disorders. More recently, she started investigating the preventive role of n-3 polyunsaturated fatty acids in these pathologies.

Dr. Eleni K. Argyrousi

Eleni K. Argyrousi is a Postdoctoral Research Scientist with the laboratory of Prof. Ottavio Arancio, Taub Institute, Columbia University, USA. Her main research interests are neurodegenerative diseases, pathogenesis in Alzheimer’s disease, phosphodiesterase inhibitors, tau pathology, memory processes, and plasticity mechanisms.

Presentation

Time

Chair Introduction: Prof. Dr. Dmitry Lim

3:00 p.m. (CEST)

Dr. Sara Merlo:

"Beta-amyloid and microglia: mechanisms for neuroprotection"

3:05 p.m. (CEST)

Q&A

3:25 p.m. (CEST)

Mr. Shun Fat Lau:

"The functional roles of IL33/ST2 signaling in modulating microglial phenotypes in Alzheimer's disease"

3:30 p.m. (CEST)

Q&A

3:50 p.m. (CEST)

Dr. Maria Grazia Morgese:

"Depressive like behavior associated with amyloid beta: protective role of n-3 polyunsaturated fatty acids"

3:55 p.m. (CEST)

Q&A

4:15 p.m. (CEST)

Dr. Eleni K. Argyrousi:

"Amyloid-beta-induced impairment of long-term synaptic plasticity and memory is tau independent"

4:20 p.m. (CEST)

Q&A

4:40 p.m. (CEST)

Concluding remarks

4.45 p.m. (CEST)