Special Issue "Pathogenesis and Potential Antiviral Targets of SARS-CoV-2"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "SARS-CoV-2 and COVID-19".

Deadline for manuscript submissions: closed (31 August 2021).

Special Issue Editor

Dr. Anne Goffard
E-Mail Website
Guest Editor
Centre d'Infection et d'Immunité de Lille, Lille, France
Interests: Virologie, Virologie Médicale, Coronavirus, Virus respiratoires, Emergence

Special Issue Information

Dear Colleagues,

At the end of 2019, SARS-CoV-2 emerged in the human population leading to the pandemic we are experiencing today. Very quickly, physicians mobilized to take care of patients. Over the past year, they have learned how to improve patient management to limit the after-effects and reduce mortality. At the same time, the scientific community has been mobilized to design diagnostic tools, vaccines and try to find treatments.

For the virology community, this emergence represents an extraordinary challenge: understanding how a coronavirus emerges, evolves and adapts to the human population, exploring interactions with the immune system and cellular machinery to explain the inflammatory attacks observed, characterizing viral proteins and enzymes to help design specific and effective antivirals. More than a year after the emergence of CoV-2-SARS, this special issue proposes to take stock of the emergence of SARS-CoV-2 and its variability, the characterization of viral proteins and enzymes, and potential therapeutic targets. 

Dr. Anne Goffard
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • SARS-CoV-2
  • emergence
  • variability
  • antiviral drugs
  • structural proteins and glycoproteins
  • RNA dependent RNA polymerase
  • protease

Published Papers (1 paper)

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Research

Article
Disinfection of SARS-CoV-2 Contaminated Surfaces of Personal Items with UVC-LED Disinfection Boxes
Viruses 2021, 13(4), 598; https://doi.org/10.3390/v13040598 - 31 Mar 2021
Cited by 1 | Viewed by 978
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted from person to person by close contact, small aerosol respiratory droplets, and potentially via contact with contaminated surfaces. Herein, we investigated the effectiveness of commercial UVC-LED disinfection boxes in inactivating SARS-CoV-2-contaminated surfaces of [...] Read more.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted from person to person by close contact, small aerosol respiratory droplets, and potentially via contact with contaminated surfaces. Herein, we investigated the effectiveness of commercial UVC-LED disinfection boxes in inactivating SARS-CoV-2-contaminated surfaces of personal items. We contaminated glass, metal, and plastic samples representing the surfaces of personal items such as smartphones, coins, or credit cards with SARS-CoV-2 formulated in an organic matrix mimicking human respiratory secretions. For disinfection, the samples were placed at different distances from UVC emitting LEDs inside commercial UVC-LED disinfection boxes and irradiated for different time periods (up to 10 min). High viral loads of SARS-CoV-2 were effectively inactivated on all surfaces after 3 min of irradiation. Even 10 s of UVC-exposure strongly reduced viral loads. Thus, UVC-LED boxes proved to be an effective method for disinfecting SARS-CoV-2-contaminated surfaces that are typically found on personal items. Full article
(This article belongs to the Special Issue Pathogenesis and Potential Antiviral Targets of SARS-CoV-2)
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