Pharmacology and Toxicology in Veterinary Paediatrics

A special issue of Veterinary Sciences (ISSN 2306-7381).

Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 5676

Special Issue Editor


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Guest Editor
Department of Veterinary Science, University of Turin, 10095 Grugliasco, Italy
Interests: pharmacology; pharmacodynamics; pets; new companion animals; cell culture; nsaids; antibiotics; antimicrobial resistance; pharmacovigilance; pharmacosurveillance
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Special Issue Information

Dear Colleagues,

Pets are more and more considered as family members and it is not unusual to listen to people speak about puppies as “babies”. A simple reality is hidden behind this curious statement: people expect the same high-quality medical assistance for their pets as they expect for themselves. Considering specifically veterinary pediatrics, a lot of therapeutic protocols and information are anecdotical and derived from human medicine. Twenty years after its first edition, “Veterinary pediatrics: dogs and cats from birth to six months” by J.D. Hoskins still represents the sole milestone not only for clinicians but also for pharmacologists and toxicologists. According to these concepts, it seems clear that it is necessary to improve the knowledge about pharmacology and toxicology in veterinary pediatrics. Veterinary Sciences has organized a Special Issue related to these topics, in which I hope that clinicians and researchers will collaborate and share their knowledge providing reviews, original papers, and short communications contributing to setting a new milestone for veterinary pediatrics.

Dr. Cristina Vercelli
Guest Editor

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Keywords

  • puppies
  • pharmacology
  • veterinary pediatrics
  • toxicology
  • therapeutics

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Published Papers (1 paper)

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7 pages, 1671 KiB  
Case Report
Suspected Drinking Water Poisoning in a Domestic Kitten with Methemoglobinemia
by Francesca Fidanzio, Andrea Corsini, Kevin Pascal Spindler and Serena Crosara
Vet. Sci. 2021, 8(11), 243; https://doi.org/10.3390/vetsci8110243 - 20 Oct 2021
Cited by 2 | Viewed by 4869
Abstract
A 4-month-old male indoor cat was referred for dyspnea, mental dullness and weakness, which appeared two days earlier. The cat had been adopted at 3 months of age. Physical exam showed cyanosis, dyspnea and mild hypothermia. The “spot test” was supportive of methemoglobinemia. [...] Read more.
A 4-month-old male indoor cat was referred for dyspnea, mental dullness and weakness, which appeared two days earlier. The cat had been adopted at 3 months of age. Physical exam showed cyanosis, dyspnea and mild hypothermia. The “spot test” was supportive of methemoglobinemia. Co-oximetry blood gas analysis revealed severe methemoglobinemia (81.40%), severe hyperchloremia and mild hyponatremia. CBC, biochemistry and urinalysis were within normal limits, blood smear showed the presence of Heinz bodies. Treatment was instituted with oxygen therapy, methylene blue 1% solution, ascorbic acid, intravenous fluid therapy. The clinical course was favorable with rapid improvement of cyanosis and methemoglobinemia (4.2%). Acquired methemoglobinemia was hypothesized. Two weeks after discharge the cat was asymptomatic but mild methemoglobinemia (15.60%) and hyperchloremia were evident. Exposure to oxidants contained in drinking water was suspected so the owners were instructed to use bottled water only. One month later the cat was asymptomatic, and methemoglobinemia and chloremia were within normal limits. Even if a congenital form due to cytochrome b5 reductase deficiency cannot be ruled out, drinking water intoxication is the most likely cause of methemoglobinemia in this cat. Full article
(This article belongs to the Special Issue Pharmacology and Toxicology in Veterinary Paediatrics)
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