Scientific Prevention and Control of Porcine Viral Diarrhea

A special issue of Veterinary Sciences (ISSN 2306-7381).

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2827

Special Issue Editors

Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China
Interests: swine enteric coronaviruses; diagnosis; prevention and control techniques of swine viral diarrhea diseases; development of vaccines against swine viral diarrhea pathogens
College of Animal Science and Technology, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou 311300, China
Interests: swine enteric coronaviruses; epidemiological investigation; antiviral drugs; vaccines

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Guest Editor
Department of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA
Interests: swine enteric coronaviruses; virus transmission and evolution; viral entry and replication; antiviral drugs and vaccines

Special Issue Information

Dear Colleagues,

The global swine industry is facing major new and old challenges caused by emerging and re-emerging viral infections. Virus-induced diarrhea is the foremost challenging factor restricting the healthy development of the swine industry. These swine enteric diarrhea viruses include porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), and porcine rotavirus (PoRV), as well as emerging viruses such as swine acute diarrhea syndrome-coronavirus (SADS-CoV), porcine deltacoronavirus (PDCoV), porcine kobuvirus (PkoV) and porcine bocavirus (PboV), etc. Given the contribution of swine production to food security, new measures and basic knowledge are needed when attempting to control the spread of these swine enteric diarrhea.

For this purpose, in this Special Issue we invite porcine virologists worldwide to submit their the latest research findings in the form of original research papers or communications, or to propose reviews related to the epidemiology, development and evaluation of diagnostic assays; virus discovery; transmission pathways; virulence; clinical aspects and vaccines. These research findings will help to address the future challenges for the global swine industry.

Dr. Da Shi
Dr. Mingjun Su
Dr. Jialin Zhang
Guest Editors

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Keywords

  • porcine vaccines
  • animal models for vaccine evaluation
  • vaccines for emerging disease
  • vaccines against novel virus
  • novel vaccine adjuvant
  • novel vaccine technology

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Published Papers (1 paper)

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Review

12 pages, 1556 KiB  
Review
A Systematic Review: Is Porcine Kobuvirus Causing Gastrointestinal Disease in Young Pigs?
by Esben Østergaard Eriksen
Vet. Sci. 2023, 10(4), 286; https://doi.org/10.3390/vetsci10040286 - 11 Apr 2023
Cited by 3 | Viewed by 1884
Abstract
Since porcine kobuvirus (PKV) was first described in 2008, researchers have speculated whether the virus is of clinical importance. This systematic literature review answers the question: Is porcine kobuvirus a cause of gastrointestinal disease in young pigs? A case-control study showed that PKV [...] Read more.
Since porcine kobuvirus (PKV) was first described in 2008, researchers have speculated whether the virus is of clinical importance. This systematic literature review answers the question: Is porcine kobuvirus a cause of gastrointestinal disease in young pigs? A case-control study showed that PKV was not associated with neonatal diarrhea. A cohort study suffered from a very small sample size (n = 5), and in an experimental trial, the effect of PKV inoculation could not be separated from the effect of being inoculated with porcine epidemic diarrhea virus. In 13 poorly defined observational studies, more than 4000 young pigs had been assigned a diarrhea status and their feces analyzed for PKV. Unfortunately, the studies lacked well-characterized unbiased samples, and thus the strongest possible inference from these studies was that a very strong association between PKV and diarrhea is unlikely. PKV was commonly detected in non-diarrheic pigs, and this could indicate that PKV is not a sufficient cause in itself or that reinfection of individuals with some immunological protection due to previous infections is common. Conclusively, there is a lack of good evidence of PKV being a cause of gastrointestinal disease, but the sparse available evidence suggests that PKV is of limited clinical importance. Full article
(This article belongs to the Special Issue Scientific Prevention and Control of Porcine Viral Diarrhea)
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