Environmental Chemicals Exposure’s Impact on Reproductive and Developmental Health: Comprehensive Evidence for Risk Assessment

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Reproductive and Developmental Toxicity".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 68

Special Issue Editors


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Guest Editor
School of Public Health, Nanjing Medical University, Nanjing, China
Interests: environmental health; reproductive toxicology; emerging contaminants; exposome; metabolome; microbiome
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Lawrence Berkeley National Laboratory, Biological Systems and Engineering Division, Berkeley, CA 94720, USA
Interests: cancer biomarkers; radiation toxicology; environmental carcinogenesis; genetic susceptibility

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Guest Editor Assistant
School of Environmental Science and Engineering, Hainan University, Haikou 570228, China
Interests: environmental health; toxicological mechanisms; emerging contaminants; organoid models; metabolic epigenetics

Special Issue Information

Dear Colleagues,

The rapid development and widespread application of environmental chemicals have raised significant concerns regarding their potential impacts on human health, particularly those of reproductive toxicity on fertility, fetal development, and long-term population health. Although extensive data from environmental monitoring, epidemiological studies, and toxicology tests are available, these evidence streams are often evaluated separately, which can lead to biased conclusions and uncertainties in risk assessment. Integrating diverse lines of evidence is essential to comprehensively understand chemical hazards, reduce uncertainties, and achieve robust, science-based conclusions.

Therefore, this Special Issue will focus on comprehensive evidence integration from human populations, animal models, and in vitro systems, aiming to advance risk assessment frameworks for chemical exposures affecting reproductive and developmental health. Research areas may include but are not limited to the following areas:

  • developing innovative methodologies for integrating multiple kinds of evidence;
  • the application of new evidence integration strategies in reproductive and developmental toxicology;
  • the utilization of alternative testing methods and computational toxicology tools in hazard characterization and
  • the establishment of standardized, science-based frameworks for toxicity evaluation and chemical risk management.

In this Special Issue, high-quality original articles and reviews are welcomed. We look forward to receiving your contributions.

Prof. Dr. Yankai Xia
Dr. Jamie L. Inman
Guest Editors

Dr. Ruijia Zhang
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • environmental chemicals
  • reproductive toxicology
  • developmental toxicology
  • risk assessment
  • evidence integration
  • hazard identification

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