Integration of Animal Models and Omics Technologies for Exploring Toxicity Mechanisms
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Novel Methods in Toxicology Research".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 230
Special Issue Editor
Interests: toxicity; animal models; proteomics; metabolomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Toxics is pleased to announce this Special Issue, which will focus on advancing our mechanistic understanding of toxic outcomes through innovative experimental designs and integrative analytical frameworks. We invite submissions that employ diverse animal models—spanning vertebrates, invertebrates, and alternative model systems—to elucidate tissue‑specific, developmental, or systemic toxicity. Special emphasis will be placed on studies that combine high‑throughput multi‑omics technologies (e.g., transcriptomics, proteomics, metabolomics) with classical toxicological endpoints to uncover novel mechanistic pathways and robust biomarker signatures.
We welcome original research and reviews on the following topics:
- Cutting‑edge in vivo or ex vivo models to dissect toxicity mechanisms beyond apical observations;
- Applications of integrative omics to identify predictive biomarker panels for early detection or mechanistic classification;
- Cross‑species comparisons to enhance translational relevance.
This Special Issue aims to showcase interdisciplinary studies that bridge molecular phenotyping with functional toxicity assessment, fostering the development of more predictive and mechanism‑based safety evaluation paradigms.
Dr. Liang Chen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- toxicity
- animal models
- biomarker
- multi‑omics
- mechanistic toxicology
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