Endocrine Disruptors and Persistent Organic Pollutants: Their Impact on the Environment and Human Health

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Exposome Analysis and Risk Assessment".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 90

Special Issue Editors


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Guest Editor
Department of Chemistry, University of Crete, 70013 Heraklion, Greece
Interests: environmental analytical chemistry of toxic organic compounds; DBPs; endocrine disruptors; POPs; human exposure studies of legacy and emerging toxic organic contaminants and endocrine disruptors

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Guest Editor
Department of Surgery and Cancer, Imperial College London, London, UK
Interests: volatolomics; biomarker discovery; bioanalytical chemistry/method development and validation/trace analysis; mass spectrometry hyphenated with (multidimensional) chromatography; environmental exposure and risk assessment
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Special Issue Information

Dear Colleagues,

Endocrine disruptors (EDCs) and persistent organic pollutants (POPs) are environmental contaminants that persist in ecosystems and bioaccumulate through food chains. EDCs disrupt hormone functions, leading to reproductive and developmental disorders, cardiovascular diseases, and cancer. POPs are linked to diabetes, cancer, neurodevelopmental issues, and reproductive disorders.

Key EDCs include BPA, phthalates, parabens, triclosan, and PFAS, which are found in personal care products and plastics. Key POPs include organochlorine pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs), which are used as flame retardants.

Human exposure to these substances occurs through environmental contact, food, and product use, primarily via inhalation, skin contact, and ingestion. Persistent EDCs like PFAS accumulate in the blood, requiring repeated measurements to be taken during pregnancy and early childhood.

Research and review articles are needed to support the regulatory efforts essential to mitigate the environmental and health impacts of EDCs and POPs. Understanding their mechanisms of action and long-term effects is crucial for developing effective protection strategies.

Prof. Dr. Euripides G. Stephanou
Dr. Antonis Myridakis
Guest Editors

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Keywords

  • biomonitoring of EDCs and POPs
  • Prenatal exposure to mixtures of endocrine-disrupting chemicals and respiratory health in children
  • exposure to POPs and emotional and behavioral outcomes from early childhood to adolescence

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Published Papers

This special issue is now open for submission.
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