New Advances in Optical Coherence Tomography Angiography (OCTA)

A special issue of Tomography (ISSN 2379-139X).

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 4304

Special Issue Editor


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Guest Editor
Department of Ophthalmology, University of Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Interests: ophthalmology; imaging; retina; choroid; pole-to-pole surgery

Special Issue Information

Dear Colleagues,

It is my pleasure to present a Special Issue on the topic of new advances in optical coherence tomography angiography (OCTA). We are witnessing a new era of technical progress in ophthalmic imaging, in which OCTA is increasingly becoming an important pillar for our daily clinical approach. OCTA has been proven to be a highly sensitive tool to detect microvascular abnormalities in ocular, but also systemic diseases. There is growing interest in the potential use of OCTA-based biomarkers. The present Special Issue focuses on a broad range of research and clinical applications to which OCTA can be applied, according to the most updated developments. Both original research papers and review articles are welcome.

Dr. Mahdy Ranjbar
Guest Editor

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Keywords

  • OCTA
  • retina
  • choroid
  • biomarker
  • imaging
  • diagnostics
  • ophthalmology

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Published Papers (2 papers)

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Research

9 pages, 2004 KiB  
Article
Vascular Choroidal Alterations in Uncomplicated Third-Trimester Pregnancy
by Jan A. M. Sochurek, Michael Gembicki, Salvatore Grisanti and Mahdy Ranjbar
Tomography 2022, 8(5), 2609-2617; https://doi.org/10.3390/tomography8050218 - 18 Oct 2022
Cited by 3 | Viewed by 1697
Abstract
(1) Purpose: To evaluate the anatomy and perfusion of choroidal substructures in third-trimester pregnant women using optical coherence tomography (OCT) and OCT angiography (OCTA) imaging. (2) Methods: In this cross-sectional study, women in their third trimester of uncomplicated pregnancy and non-pregnant age-matched women [...] Read more.
(1) Purpose: To evaluate the anatomy and perfusion of choroidal substructures in third-trimester pregnant women using optical coherence tomography (OCT) and OCT angiography (OCTA) imaging. (2) Methods: In this cross-sectional study, women in their third trimester of uncomplicated pregnancy and non-pregnant age-matched women were recruited. Participants underwent enhanced depth imaging (EDI) OCT and OCTA. Subfoveal choroidal thickness (SFCT), as well as choroidal sublayer perfusion, were compared between groups. (3) Results: In total, 26 eyes of 26 pregnant and 26 eyes of 26 non-pregnant women were included. The median age in both groups was 29 years. The median SFCT was 332 (211–469) µm in the pregnant group and 371.5 (224–466) µm in the non-pregnant cohort (p = 0.018). The median choriocapillaris perfusion (CCP) was significantly lower in the pregnant group (46% vs. 48%, p = 0.039). Moreover, Haller’s layer perfusion correlated significantly with mean arterial pressure in non-pregnant women (CC = 0.430, p = 0.028) but not in pregnant ones (CC = 0.054, p = 0.792). (4) Conclusions: SFCT was found to be thinner and CCP was lower in third-trimester pregnant women. Hormonal changes during pregnancy and consecutive impacts on autoregulation of small choroidal vessels might play an important role. Therefore, altered choroidal measurements during third-trimester pregnancy should be carefully evaluated as, to some extent, it could be a normal physiological change. Full article
(This article belongs to the Special Issue New Advances in Optical Coherence Tomography Angiography (OCTA))
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7 pages, 222 KiB  
Article
Impact of Silicone Oil Removal on Macular Perfusion
by Michelle Prasuhn, Felix Rommel, Armin Mohi, Salvatore Grisanti and Mahdy Ranjbar
Tomography 2022, 8(4), 1735-1741; https://doi.org/10.3390/tomography8040146 - 6 Jul 2022
Cited by 4 | Viewed by 1605
Abstract
(1) Background: Silicone oil (SO) can be used as an endotamponade during vitreoretinal surgery for retinal detachment. There is emerging evidence that SO filling of the vitreous cavity and its removal may impact macular perfusion. So far, studies have not focused on choroidal [...] Read more.
(1) Background: Silicone oil (SO) can be used as an endotamponade during vitreoretinal surgery for retinal detachment. There is emerging evidence that SO filling of the vitreous cavity and its removal may impact macular perfusion. So far, studies have not focused on choroidal sublayer perfusion, yet. (2) Methods: Optical coherence tomography angiography was applied in 19 patients with SO endotamponade before and four weeks after removal of SO. (3) Results: Perfusion of choriocapillaris increased significantly after SO removal, while perfusion of Haller’s and Sattler’s layer decreased significantly. (4) Conclusions: Removal of SO impacts choroidal perfusion and leads to a perfusion shift within choroidal sublayers. This study underlines that it is worth to conduct larger prospective studies that evaluate the choroidal perfusion and its functional implications in more detail. Full article
(This article belongs to the Special Issue New Advances in Optical Coherence Tomography Angiography (OCTA))
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