Orthopaedic Radiology: Establishing Radiologic Measurements as Diagnostic Tools and Criteria for Treatment

A special issue of Tomography (ISSN 2379-139X).

Deadline for manuscript submissions: 31 December 2026 | Viewed by 1433

Editor


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Guest Editor
Department of Orthopedic Surgery and Neurosurgery, Duke University Medical Center, Durham, NC, USA
Interests: MRI; CT; diagnostic imaging; orthopaedic radiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We recently completed a Tomography Special Issue titled “Orthopaedic Radiology: Clinical Diagnosis and Application”. The topic is considered impactful and has endless possibilities. We have just scratched the surface; there is more work to be done. Thus, we feel the need to continue to publish on this topic. Radiographic modalities are integral to the diagnoses of orthopaedic and spine diseases, yet they are still considered by many to be secondary to clinical presentation. The pitfall to this thinking, however, is that the myriad of symptomologies and physical presentations can lead to a lack of objectivity and reproducibility. Radiologic measurements and established thresholds may improve diagnoses and ultimately have a greater impact on overall patient care.

This Special Issue is titled “Orthopaedic Radiology: Establishing Radiologic Measurements as Diagnostic Tools and Criteria for Treatment”. Again, we seek to highlight innovations in MSK imaging that refine diagnostic accuracy and expand the role of imaging. We invite original research, comprehensive reviews, and case-based studies exploring advances in MSK imaging techniques. We emphasize research that can aid in establishing objective radiologic criteria for diagnosing conditions that traditionally place greater emphasis on clinical presentation.

This issue aims to expand the work published in the previous Special Issue and highlight the diagnostic use of advanced imaging as a standardized evaluation and treatment tool. We welcome contributions that help establish MSK radiology as a precise diagnostic instrument.

Dr. Olumide A. Danisa
Guest Editor

Manuscript Submission Information

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Keywords

  • advanced imaging
  • CT—computerized tomography
  • MRI—magnetic resonance imaging
  • fluoroscopy
  • diagnosis

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Published Papers (3 papers)

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Research

9 pages, 3799 KB  
Article
Relationship Between Cervical Central Canal and Neural Foraminal Dimensions in a Normative Population
by Kai Nguyen, Zachary Brandt, David Shin, Carson Cummings, Rohan Kubba, Jacob Razzouk, Davis Carter, Mei Carter, Wayne Cheng and Olumide Danisa
Tomography 2026, 12(6), 86; https://doi.org/10.3390/tomography12060086 - 12 Jun 2026
Viewed by 117
Abstract
Background/Objectives: The relationship between cervical central canal and neural foraminal dimensions remains undefined. This study examined correlations between these structures in a young adult CT cohort screened to exclude apparent cervical spinal pathology. Methods: We retrospectively reviewed computed tomography images of 1000 patients [...] Read more.
Background/Objectives: The relationship between cervical central canal and neural foraminal dimensions remains undefined. This study examined correlations between these structures in a young adult CT cohort screened to exclude apparent cervical spinal pathology. Methods: We retrospectively reviewed computed tomography images of 1000 patients aged 18 to 35 years screened to exclude apparent cervical spinal pathology. Central canal dimensions included anteroposterior diameter, interpedicular distance, and cross-sectional area. Neural foraminal dimensions included axial width, craniocaudal height, and area. Pearson correlation tests were used to assess associations between the central canal and neural foraminal dimensions. Results: Neural foraminal area showed the most consistent associations with interpedicular distance bilaterally, though these relationships were modest-to-moderate in magnitude. Axial width and craniocaudal height exhibited no consistent correlations with central canal dimensions. No strong correlations were observed between any combination of central canal and neural foraminal dimensions at any disc level. Conclusions: In this young adult CT cohort without apparent cervical spinal pathology, cervical central canal and neural foraminal dimensions demonstrated no strong correlations across levels. These findings suggest that central canal dimensions should not be used as a surrogate for neural foraminal dimensions in quantitative morphometric assessment. Full article
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14 pages, 1259 KB  
Article
Quantitative CT-Derived Volumetric Bone Mineral Density Threshold for Predicting Cage Subsidence After Oblique Lumbar Interbody Fusion
by Ji-Le Jiang, Teng-Hui Ge, Zhong-Ning Xu, Jing-Ye Wu and Yu-Qing Sun
Tomography 2026, 12(5), 72; https://doi.org/10.3390/tomography12050072 - 14 May 2026
Viewed by 298
Abstract
Background: Cage subsidence (CS) is among the main complications after oblique lumbar interbody fusion (OLIF) and may lead to the failure of indirect decompression. Accurate preoperative bone quality assessment is critical for risk stratification, yet the optimal imaging modality and diagnostic threshold remain [...] Read more.
Background: Cage subsidence (CS) is among the main complications after oblique lumbar interbody fusion (OLIF) and may lead to the failure of indirect decompression. Accurate preoperative bone quality assessment is critical for risk stratification, yet the optimal imaging modality and diagnostic threshold remain unclear. Objectives: This study aimed to determine a quantitative computed tomography (QCT)-derived volumetric bone mineral density (vBMD) threshold for predicting CS after OLIF with posterior fixation. Methods: Patients undergoing OLIF with posterior fixation between July 2017 and March 2020 were retrospectively enrolled. Preoperative vBMD was measured using QCT as the average L2–L4 trabecular volumetric BMD. CS was defined as a loss of more than 2 mm of disk height on sagittal midline CT views between 3 days postoperatively and the last follow-up. Clinical and radiographic parameters including gender, age, body mass index, vBMD, number of operative levels, cage dimensions, disk height, segmental lordosis, intraoperative endplate injury, and fusion status were analyzed. Results: 86 patients (107 operative levels) with a mean follow-up of 20.6 months were included; 25 levels (23.4%) developed CS. Multivariate logistic regression identified vBMD (p < 0.001; OR 0.947; 95% CI 0.923–0.972) and intraoperative endplate injury (p = 0.031; OR 3.640; 95% CI 1.125–11.776) as independent risk factors. The area under the receiver operating characteristic curve (AUC) for vBMD was 0.847 (95% CI, 0.762–0.932), with an optimal threshold of 83.0 mg/cm3 (sensitivity 84.0%, specificity 76.8%). This threshold closely aligns with the American College of Radiology QCT criterion for osteoporosis (80 mg/cm3); however, given that it was derived from a single-center retrospective cohort, external validation in multi-center studies is warranted before broad clinical adoption. Fusion rates differed significantly between CS and non-CS groups (84.0% vs. 96.3%, p = 0.029). Conclusions: QCT-derived vBMD provides a phantom-calibrated, protocol-standardized metric for preoperative risk stratification of cage subsidence after OLIF. Full article
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17 pages, 1595 KB  
Article
Radiographic Evaluation of Spinopelvic Sagittal Alignment Anatomy in Juvenile and Adolescent Idiopathic Scoliosis Patients
by Ozden Bedre Duygu, Figen Govsa, Anil Murat Ozturk and Gokhan Gokmen
Tomography 2026, 12(4), 52; https://doi.org/10.3390/tomography12040052 - 7 Apr 2026
Viewed by 687
Abstract
Background and Objectives: The association between spinal and pelvic alignment significantly impacts sagittal balance in adults. This study, that is retrospective, aims to investigate sagittal alignment anatomy of the pelvis and spine in juvenile idiopathic scoliosis (JIS) and adolescent idiopathic scoliosis (AIS) [...] Read more.
Background and Objectives: The association between spinal and pelvic alignment significantly impacts sagittal balance in adults. This study, that is retrospective, aims to investigate sagittal alignment anatomy of the pelvis and spine in juvenile idiopathic scoliosis (JIS) and adolescent idiopathic scoliosis (AIS) patients. Materials and Methods: We evaluated nine sagittal parameters from lateral radiographs of 100 JIS and AIS patients, including thoracic kyphosis (TKA), lumbar lordosis (LLA), pelvic tilt (PTA), pelvic incidence (PIA), spinosacral (SSA), sacral slope (SSLA), C7 tilt angles (C7-TA), sagittal vertical axis length (SVAL), and odontoid process hip axis angle (OPHAA) using the ImageJ program. Participants were classified based on their coronal curve group. Analysis of variance compared parameters between curve groups, and Pearson coefficients assessed the relationship between all parameters (p < 0.05). Results: Female participants had an average age of 13.4, and male participants had an average age of 13.0. Female participants had an average scoliosis degree of 19.3, while male participants had 15.2. PIA, PTA, SSLA, and SSA values were significantly higher in women participants than in men participants (p < 0.05). Additionally, PIA, PTA, SSLA, SSA, and OPHAA values were significantly lower in participants with a lower scoliosis degree (p < 0.05). We observed a moderately positive association between LLA and TKA, PIA, SSA, and C7-TA. There was also a moderate positive association between spinopelvic alignment parameters and the degree of scoliosis in participants. Conclusions: Easily measured values such as PIA, PTA, SSLA, SSA, and OPHAA may be related to severity of vertebral column deformities in patients, making them valuable for monitoring scoliosis patients. Full article
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