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Systems publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Scheduling and Optimization in Production and Transportation Systems

edited by

Peng Guo

and Sihan Huang

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1641 | Submission Open

Keywords: scheduling optimization; production systems; transportation systems; advanced scheduling algorithms; real-time data analytics; heuristic and metaheuristic methods; supply chain optimization; machine learning in scheduling; resilience in scheduling

(This special issue belongs to the Section Supply Chain Management)

Complex Systems Theory in Regional and Urban Marketing: Strategies for Resilient, Sustainable, and Smart Cities

edited by

Luis Manuel Cerdá Suárez

submission deadline 31 Dec 2025 | 1 articles | Viewed by 647 | Submission Open

Keywords: complex systems theory in social sciences; urban marketing; resilient cities; sustainable cities; smart cities; citizen participation in cities; agent-based simulation; urban planning; regional and urban development

(This special issue belongs to the Section Complex Systems and Cybernetics)

Operations Research in Optimization of Supply Chain Management

edited by

Farnaz Ghazi-Nezami

submission deadline 31 Dec 2025 | Viewed by 162 | Submission Open

Keywords: operations research; supply chain optimization; mathematical modeling; logistics and transportation

(This special issue belongs to the Section Supply Chain Management)

Navigating Complexity in a Changing World: Challenges and Opportunities for Sustainable and Resilient Supply Chains

edited by Jaeyoung Oh, Joonhwan In and

Minseok Park

submission deadline 31 Dec 2025 | Viewed by 139 | Submission Open

Keywords: sustainability; resilience; trade-offs and synergies; ESG strategies; data-driven decision-making; AI and machine leaning in supply chains; circular economy; supply chain risk management; supply chains for SMEs and service industries; policy and regulation for ESGs

(This special issue belongs to the Section Supply Chain Management)

Enterprise Sustainability: From Management System to Corporate Social Responsibility

edited by

Rute Maria Gomes Abreu

and

Hualiang Lu

submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open

Keywords: sustainability; management system; corporate social responsibility; business management; governance; ESG

(This special issue belongs to the Section Systems Practice in Social Science)

Sustainable Urban Transport Systems

edited by Konstantina Anastasiadou and

Nikolaos Gavanas

submission deadline 31 Dec 2025 | Viewed by 91 | Submission Open

Keywords: sustainable urban mobility; transport planning; urban planning; sustainability; urban transport systems; micromobility; sustainable transport

Intelligent Optimization and Business Analytics for Supply Chain and Logistics Management in the Age of Industry 4.0

edited by Young Sik Cho and Euisung Jung

submission deadline 31 Dec 2025 | Viewed by 64 | Submission Open

Keywords: intelligent optimization; supply chain management; logistics; AI; machine learning; big data; blockchain; business analytics

(This special issue belongs to the Section Supply Chain Management)

Emerging Disruptions in Healthcare Systems: How Digital Innovation Is Reshaping Policy, Practice, and Patient Outcomes

edited by

Dalibor Stanimirović

submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open

Keywords: patient-centered digital innovations (eHealth); service delivery; and treatment outcomes; AI and data-driven decision support systems in strategic planning; telemedicine; remote monitoring; and mobile health (mHealth); integration and interoperability of electronic health records (EHRs); digital health literacy and user engagement strategies; governance; policies; and regulatory challenges in digital health; data privacy; security; and ethics in digital healthcare ecosystems; digital tools for public health surveillance and emergency response; socio-technical barriers and enablers of digital transformation; cross-sectoral and interdisciplinary approaches to digital health; impacts of digital health innovations on institutional/system performance

Safety, Security, and Dependability in Embedded Systems

edited by

Yutaka Matsubara

submission deadline 31 Dec 2025 | Viewed by 35 | Submission Open

Keywords: embedded system; safety; security; dependability; resilience; system of systems

(This special issue belongs to the Section Systems Engineering)

Digital Engineering: Transformational Tools and Strategies

edited by

Lawrence Dale Thomas

Ana Wooley

and Hanumanthrao Kannan

submission deadline 20 Jan 2026 | Viewed by 30 | Submission Open

Keywords: digital engineering; digital transformation; digital engineering applications; digital engineering metrics; digital engineering maturity models; data integration and interoperability

(This special issue belongs to the Section Artificial Intelligence and Digital Systems Engineering)

Systems Approach to Innovation in Construction Projects

edited by

Fahim Ullah

Ahsen Maqsoom

, Khurram Iqbal Ahmad Khan and

Amir Ghanbaripour

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2478 | Submission Open

Keywords: complex systems; construction projects; construction project management; innovation; systems thinking; systems approach

(This special issue belongs to the Section Systems Engineering)

Business Process Management Based on Big Data Analytics

edited by

Jorge Oliveira e Sá

and José Luis Mota Pereira

submission deadline 31 Jan 2026 | Viewed by 394 | Submission Open

Keywords: business process management; big data; decision making; data analytics; AI integration

(This special issue belongs to the Section Systems Practice in Social Science)

Digital Engineering Strategies of Smart Production Systems

edited by

Khaled Benfriha

and Esma TALHI

submission deadline 31 Jan 2026 | Viewed by 380 | Submission Open

Keywords: smart production system; digital transition strategy; digitalization methods; integration technologies methods; data-driven control; cloud manufacturing; IIoT systems cyber– physical production systems; industrial distributed systems; smart manufacturing control systems; digital twin; mobile manipulators; state of research on digital engineering strategies; smart production features

(This special issue belongs to the Section Systems Engineering)

Economic System Management, Sustainability, and Innovation in Digital Environments

edited by Raquel Ibar-Alonso, Maria-Carmen García-Centeno and

Raquel Quiroga-Garcia

submission deadline 31 Jan 2026 | Viewed by 49 | Submission Open

Keywords: digital transformation; innovation; big data analytics; artificial intelligence; disruptive technologies; resource optimization; sustainability; competitiveness

(This special issue belongs to the Section Systems Practice in Social Science)

Uncertainty-Aware Decision Making in Supply Chain and Logistics: Integration of Fuzzy, Stochastic, and Analytical Approaches

edited by Omid Jadidi and Fatemeh Firouzi

submission deadline 31 Jan 2026 | Viewed by 46 | Submission Open

Keywords: supply chain uncertainty; fuzzy and stochastic optimization; decision support systems; resilient and sustainable supply chains; data-driven decision making; hybrid modeling approaches

Operations Management in Healthcare Systems

edited by

Aydin Teymourifar

submission deadline 28 Feb 2026 | Viewed by 516 | Submission Open

Keywords: healthcare systems; system design; system dynamics; simulation and modelling; contract mechanisms in healthcare systems; estimation; time series model; machine learning; decision-making; productivity and efficiency

(This special issue belongs to the Section Systems Practice in Social Science)

Servitization and Product–Service Systems (PSS): Design, Management, and Ethics for Human Well-Being

edited by

Bach Quang Ho

, Yutaro Nemoto and

Kentaro Watanabe

submission deadline 28 Feb 2026 | Viewed by 82 | Submission Open

Keywords: product– service systems; servitization; well-being; service design; social sustainability; digital technologies; extended producer responsibility

(This special issue belongs to the Section Systems Practice in Social Science)

Systems Approaches in E-Commerce and Business Intelligence: Innovations and Applications

edited by Jong-min Kim and

Rob Kim Marjerison

submission deadline 28 Feb 2026 | Viewed by 44 | Submission Open

Keywords: e-commerce; AI Systems; innovation; recent technological advances; competitive advantage; systems approaches

Smarter Infrastructure System Design for Sustainability

edited by Nilupa Herath and

Madhuwanthi Rupasinghe

submission deadline 28 Feb 2026 | Viewed by 5 | Submission Open

Keywords: smart infrastructure; sustainable design; digital technologies; resilient systems; sustainable materials

(This special issue belongs to the Section Systems Engineering)

Applying Systems Science to Place-Based Systems Change Efforts: Theoretical and Methodological Advances

edited by Therese Riley

submission deadline 28 Feb 2026 | Viewed by 1 | Submission Open

Keywords: place-based systems change; systems theory; systems approaches; place-based approaches; complex social problems; monitoring and evaluation

Model-Based Systems Engineering and Integration

edited by

Lawrence Dale Thomas

submission deadline 28 Feb 2026 | Submission Open

Keywords: model-based systems engineering; systems engineering; systems integration; verification; validation; test planning; system test

(This special issue belongs to the Section Systems Engineering)

Public Value and Public Service: Reconsidering Humans in a Vuca-D Society

edited by Giuseppe Modarelli, Mouna Nasr, Seda Çeken and