State-of-the-Art Research and Emerging Innovations in Plastic and Aesthetic Surgery

A special issue of Surgeries (ISSN 2673-4095).

Deadline for manuscript submissions: 30 September 2026 | Viewed by 2678

Special Issue Editor


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Guest Editor
Department of Plastic, Reconstructive and Aesthetic Surgery, Brussels University Hospital (UZ Brussel), Brussels, Belgium
Interests: plastic surgery; aesthetic surgery; breast reconstruction

Special Issue Information

Dear Colleagues,

Plastic and aesthetic surgery continues to evolve rapidly, driven by technological advances, refined surgical techniques, and an ever-growing emphasis on patient-centred outcomes. This Special Issue will bring together state-of-the-art research highlighting both clinical and scientific progress across the field. Topics of interest include reconstructive strategies, advances in microsurgery, innovations in breast and facial surgery, body contouring, regenerative medicine, and novel applications of technology such as artificial intelligence and computer-assisted planning.

We also welcome contributions addressing perioperative care, complication management, and long-term outcome assessment, as well as review articles synthesising current evidence and outlining future directions. By encompassing both reconstructive and aesthetic domains, this Special Issue aims to showcase the breadth of modern practice and the integration of innovation into everyday surgical care.

Our goal is to provide an international platform for surgeons and researchers to share expertise, stimulate academic discussion, and shape the next generation of developments in plastic and aesthetic surgery.

Dr. Ayush K. Kapila
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Surgeries is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plastic surgery
  • aesthetic surgery
  • artificial intelligence

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Published Papers (3 papers)

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Research

15 pages, 1656 KB  
Article
Immediate Breast Reconstruction in Skin-Reducing Mastectomy Using Prepectoral Approach with Porcine-Derived Dermal Matrix and Autologous Dermal Sling: A Retrospective Observational Study
by Luca Galassi, Simone Scotti, Federica Facchinetti and Roberta Gilardi
Surgeries 2026, 7(1), 41; https://doi.org/10.3390/surgeries7010041 - 23 Mar 2026
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Abstract
Background: Immediate prepectoral implant-based breast reconstruction (IBR) following skin-reducing mastectomy (SRM) preserves the pectoralis major muscle, improving recovery and aesthetics. A dual-layer technique combining porcine-derived acellular dermal matrix (ADM) with an inferior autologous dermal sling may enhance implant support, vascularization, and lower-pole stability, [...] Read more.
Background: Immediate prepectoral implant-based breast reconstruction (IBR) following skin-reducing mastectomy (SRM) preserves the pectoralis major muscle, improving recovery and aesthetics. A dual-layer technique combining porcine-derived acellular dermal matrix (ADM) with an inferior autologous dermal sling may enhance implant support, vascularization, and lower-pole stability, particularly in patients with macromastia or ptosis. Methods: This retrospective single-center study included 20 patients (24 breasts) who underwent SRM with immediate prepectoral IBR using the dual-layer technique between January 2023 and May 2025. Demographic, oncologic, and perioperative data were collected prospectively. Complications were classified by severity, and patient-reported outcomes were evaluated using the BREAST-Q scale preoperatively and at 1, 3, 6, and 12 months postoperatively. Statistical analysis included paired t-tests, Shapiro–Wilk tests, and effect size estimation (Cohen’s dz). Results: Mean age was 42 ± 6.3 years and BMI 26.1 ± 3.2 kg/m2. Mean mastectomy specimen weight was 432.5 ± 120.8 g, and implant volume 375 ± 60 cc. No reconstruction failures or infections occurred. Early complications were reported in 20.8% of breasts, including superficial nipple–areola complex epidermolysis (8.3%), seroma (4.2%), and hematoma (4.2%), all managed conservatively. At 12 months, BREAST-Q scores improved significantly: satisfaction with breasts increased from 63 ± 8 to 89 ± 11 (p < 0.001); psychosocial well-being from 60 ± 10 to 81 ± 11 (p < 0.001); and physical well-being from 62 ± 7 to 82 ± 10 (p < 0.001). Conclusions: Dual-layer prepectoral reconstruction using porcine ADM and autologous dermal sling is safe, provides durable implant stability, and significantly improves patient satisfaction and quality of life following SRM. Full article
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10 pages, 991 KB  
Article
Is Lipofilling Predictable? Factors Associated with Delayed Lipofilling for Rippling After Prepectoral Direct-to-Implant Breast Reconstruction
by Marco Franchello, Gianluca Marcaccini, Claudia Chiarini, Roberto Cuomo and Diletta Maria Pierazzi
Surgeries 2026, 7(1), 18; https://doi.org/10.3390/surgeries7010018 - 26 Jan 2026
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Abstract
Background/Objectives: Prepectoral direct-to-implant reconstruction is widely used, but implant rippling often necessitates lipofilling. This study aimed to identify preoperative and perioperative factors associated with delayed lipofilling. Methods: A retrospective cohort of consecutive patients who underwent immediate prepectoral implant reconstruction (April 2023–September 2024) was [...] Read more.
Background/Objectives: Prepectoral direct-to-implant reconstruction is widely used, but implant rippling often necessitates lipofilling. This study aimed to identify preoperative and perioperative factors associated with delayed lipofilling. Methods: A retrospective cohort of consecutive patients who underwent immediate prepectoral implant reconstruction (April 2023–September 2024) was analyzed. Demographic data, BMI, smoking, comorbidities, oncologic treatments, surgical factors, and tumor location were recorded. Patients were divided according to whether delayed lipofilling was required. Univariate analysis was performed using Mann–Whitney U and Fisher’s exact tests. Results: Fifty-eight patients were included; approximately one-third required lipofilling. Patients who underwent lipofilling were younger and had lower BMI than those who did not. Tumor location was strongly associated with the outcome: upper inner quadrant tumors were consistently linked to delayed lipofilling, whereas upper outer quadrant tumors were more frequently observed in the group not requiring revision. Smoking history and planned radiotherapy showed nonsignificant trends toward higher lipofilling rates. No differences were found for diabetes or corticosteroid therapy. Conclusions: Younger age, low BMI, and tumor location, particularly in the upper inner quadrant, were key factors associated with delayed lipofilling after prepectoral reconstruction. These variables may support preoperative counseling and follow-up planning to better anticipate secondary procedures and optimize aesthetic outcomes. Full article
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13 pages, 3446 KB  
Article
Incidental Carcinomas and Lesions with Uncertain Malignant Potential (B3) Discovered During Symmetrization Mammoplasty in Breast Cancer Patients—Retrospective Single-Center Experience
by Daciana Grujic, Horia Cristian, Alis Dema, Mihai Iliescu Glaja, Teodora Hoinoiu, Fabiana Simion, Daniel Pit, Isabela Caizer-Găitan and Cristina Oprean
Surgeries 2026, 7(1), 10; https://doi.org/10.3390/surgeries7010010 - 4 Jan 2026
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Abstract
Although occult breast carcinomas and lesions with uncertain malignant potential are rare, their incidental discovery during symmetrizing mammoplasty can significantly alter the treatment approaches and cancer staging. In the context of oncoplastic surgery, the systematic evaluation of the contralateral breast is a clinical [...] Read more.
Although occult breast carcinomas and lesions with uncertain malignant potential are rare, their incidental discovery during symmetrizing mammoplasty can significantly alter the treatment approaches and cancer staging. In the context of oncoplastic surgery, the systematic evaluation of the contralateral breast is a clinical priority that has been underexplored in Eastern Europe. Background/Objectives: This study aimed to assess the incidence and histological characteristics of incidental carcinomas and B 3 lesions detected during contralateral symmetry mammoplasty in patients with breast cancer. Methods: This retrospective study was conducted at the Plastic and Reconstructive Surgery Clinic of the “Pius Brînzeu” County Emergency Clinical Hospital in Timisoara, Romania, over six years (2018–2024), and included 180 of 256 patients who underwent contralateral breast symmetrization. Results: Among the 180 patients, 21 (11.66%) had incidental findings: eight (4.44%) had contralateral carcinomas, and 13 (7.22%) had B3 lesions. The histopathological types identified were invasive ductal carcinoma NST (one case), ductal carcinoma in situ (one case), invasive lobular carcinoma (five cases), and mucinous/papillary carcinoma (one case). Compared to the reported international range of 2–10%, our observed incidence of 11.66% reflects the unique aspects of our patient cohort and the thoroughness of our histological analyses. Conclusions: Detection of contralateral carcinomas and B3 lesions during symmetry mammoplasties underscores the importance of a multidisciplinary approach, comprehensive bilateral screening, and detailed histopathological examination of specimens. Full article
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